Efeitos agudos e crônicos do exercício isométrico de preensão manual nas variáveis hemodinâmicas, neuromusculares e bioquímicas em idosos institucionalizados
Ano de defesa: | 2019 |
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Autor(a) principal: | |
Orientador(a): | |
Banca de defesa: | |
Tipo de documento: | Tese |
Tipo de acesso: | Acesso aberto |
Idioma: | por |
Instituição de defesa: |
Universidade Católica de Brasília
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Programa de Pós-Graduação: |
Programa Stricto Sensu em Educação Física
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Departamento: |
Escola de Saúde e Medicina
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País: |
Brasil
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Palavras-chave em Português: | |
Palavras-chave em Inglês: | |
Área do conhecimento CNPq: | |
Resumo em Inglês: | The objective of this study was to verify the acute and chronic effect of isometric handgrip (IHG) exercise on the hemodynamic and biochemical variables in the prehypertensive and hypertensive elderly subjects. Two studies were performed: 1º Ten hypertensive elderly (♀ = 7), 73.2 ± 2.2 years, 13.2 ± 3.1 years of hypertension, systolic blood pressure (SBP) 135.1 ± 6.5 mm Hg and diastolic blood pressure (DBP) of 76.6 ± 3.4 mm Hg were submitted to two acute sessions, a 3% control and another to 30% of maximal isometric voluntary contraction (MIVC) using a handgrip hydraulic dynamometer (Jamar, IL, USA). Participants completed eight sets of one minute isometric contraction, bilaterally, with one-minute pause. Blood pressure (BP) and heart rate (HR) were measured at rest and at 1, 5, 10, 15, 30, 45 and 60 min postexercise. Blood lactate and salivary nitric oxide (NO-) were collected at rest, 0, 30 and 60 min after exercise. 2º Thirty-three elderly (♀ = 15), 75.6 ± 1.2 years, were divided into three groups: hypertensive control (CG, n = 11), prehypertensive (PHG, n = 10) and hypertensive (HG = 12). Isometric handgrip training (IHT) was performed for 8 weeks, 3 times a week on non-consecutive days. The intensity and volume of the IHT were the same as in study 1. There was a non-exercise period after the 4- week IHT. Anthropometric and biochemical variables were evaluated before and after IHT. Hemodynamic and neuromuscular variables were measured before, during and after IHT. In study 1 there was a reduction of SBP after the session of 30% MVIC from the 10th min post-exercise (p < 0.05). At 60 minutes post-exercise, SBP was lower in the 30% vs. 3% MVIC (p = 0.006). There was no difference for the other variables (p > 0.05). In study 2, IHT reduced SBP and HR in both trained groups (PHG and HG). DBP and mean BP decreased only in HG (p < 0.05). Reductions in pressure levels induced by IHT were maintained during the period without IHG exercise. There was an inverse association of ΔTrolox/TBARS and Δlactate in relation to ΔSBP (p < 0.05). ΔTBARS was positively associated with reductions in DBP and HR after IHT (p < 0.05). IHT induced increase in NO- concentrations (p < 0.05). The Δ increase in absolute handgrip strength was associated with the reduction of ΔSBP, ΔDBP, ΔHR and with increase in ΔTrolox/TBARS and ΔNO- after IHT (p < 0.05). In conclusion, study 1 demonstrated that IHG exercise induced postisometric exercise hypotension in hypertensive elderly, with no association with lactate and NO- concentrations. In study 2, IHT also induced a reduction in BP and HR levels in prehypertensive and hypertensive elderly subjects. Endotheliumdependent flow mediated vasodilation and improvement in the redox state may be the possible mechanisms involved. |
Link de acesso: | https://bdtd.ucb.br:8443/jspui/handle/tede/2598 |
Resumo: | The objective of this study was to verify the acute and chronic effect of isometric handgrip (IHG) exercise on the hemodynamic and biochemical variables in the prehypertensive and hypertensive elderly subjects. Two studies were performed: 1º Ten hypertensive elderly (♀ = 7), 73.2 ± 2.2 years, 13.2 ± 3.1 years of hypertension, systolic blood pressure (SBP) 135.1 ± 6.5 mm Hg and diastolic blood pressure (DBP) of 76.6 ± 3.4 mm Hg were submitted to two acute sessions, a 3% control and another to 30% of maximal isometric voluntary contraction (MIVC) using a handgrip hydraulic dynamometer (Jamar, IL, USA). Participants completed eight sets of one minute isometric contraction, bilaterally, with one-minute pause. Blood pressure (BP) and heart rate (HR) were measured at rest and at 1, 5, 10, 15, 30, 45 and 60 min postexercise. Blood lactate and salivary nitric oxide (NO-) were collected at rest, 0, 30 and 60 min after exercise. 2º Thirty-three elderly (♀ = 15), 75.6 ± 1.2 years, were divided into three groups: hypertensive control (CG, n = 11), prehypertensive (PHG, n = 10) and hypertensive (HG = 12). Isometric handgrip training (IHT) was performed for 8 weeks, 3 times a week on non-consecutive days. The intensity and volume of the IHT were the same as in study 1. There was a non-exercise period after the 4- week IHT. Anthropometric and biochemical variables were evaluated before and after IHT. Hemodynamic and neuromuscular variables were measured before, during and after IHT. In study 1 there was a reduction of SBP after the session of 30% MVIC from the 10th min post-exercise (p < 0.05). At 60 minutes post-exercise, SBP was lower in the 30% vs. 3% MVIC (p = 0.006). There was no difference for the other variables (p > 0.05). In study 2, IHT reduced SBP and HR in both trained groups (PHG and HG). DBP and mean BP decreased only in HG (p < 0.05). Reductions in pressure levels induced by IHT were maintained during the period without IHG exercise. There was an inverse association of ΔTrolox/TBARS and Δlactate in relation to ΔSBP (p < 0.05). ΔTBARS was positively associated with reductions in DBP and HR after IHT (p < 0.05). IHT induced increase in NO- concentrations (p < 0.05). The Δ increase in absolute handgrip strength was associated with the reduction of ΔSBP, ΔDBP, ΔHR and with increase in ΔTrolox/TBARS and ΔNO- after IHT (p < 0.05). In conclusion, study 1 demonstrated that IHG exercise induced postisometric exercise hypotension in hypertensive elderly, with no association with lactate and NO- concentrations. In study 2, IHT also induced a reduction in BP and HR levels in prehypertensive and hypertensive elderly subjects. Endotheliumdependent flow mediated vasodilation and improvement in the redox state may be the possible mechanisms involved. |
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Moraes, Milton Rocha dehttp://lattes.cnpq.br/1690322593621016http://lattes.cnpq.br/7231951956450623Souza, Luiz Humberto Rodrigues2019-06-04T12:43:10Z2019-02-26SOUZA, Luiz Humberto Rodrigues. Efeitos agudos e crônicos do exercício isométrico de preensão manual nas variáveis hemodinâmicas, neuromusculares e bioquímicas em idosos institucionalizados. 2019. 139 f. Tese (Programa Stricto Sensu em Educação Física) - Universidade Católica de Brasília, Brasília, 2019.https://bdtd.ucb.br:8443/jspui/handle/tede/2598The objective of this study was to verify the acute and chronic effect of isometric handgrip (IHG) exercise on the hemodynamic and biochemical variables in the prehypertensive and hypertensive elderly subjects. Two studies were performed: 1º Ten hypertensive elderly (♀ = 7), 73.2 ± 2.2 years, 13.2 ± 3.1 years of hypertension, systolic blood pressure (SBP) 135.1 ± 6.5 mm Hg and diastolic blood pressure (DBP) of 76.6 ± 3.4 mm Hg were submitted to two acute sessions, a 3% control and another to 30% of maximal isometric voluntary contraction (MIVC) using a handgrip hydraulic dynamometer (Jamar, IL, USA). Participants completed eight sets of one minute isometric contraction, bilaterally, with one-minute pause. Blood pressure (BP) and heart rate (HR) were measured at rest and at 1, 5, 10, 15, 30, 45 and 60 min postexercise. Blood lactate and salivary nitric oxide (NO-) were collected at rest, 0, 30 and 60 min after exercise. 2º Thirty-three elderly (♀ = 15), 75.6 ± 1.2 years, were divided into three groups: hypertensive control (CG, n = 11), prehypertensive (PHG, n = 10) and hypertensive (HG = 12). Isometric handgrip training (IHT) was performed for 8 weeks, 3 times a week on non-consecutive days. The intensity and volume of the IHT were the same as in study 1. There was a non-exercise period after the 4- week IHT. Anthropometric and biochemical variables were evaluated before and after IHT. Hemodynamic and neuromuscular variables were measured before, during and after IHT. In study 1 there was a reduction of SBP after the session of 30% MVIC from the 10th min post-exercise (p < 0.05). At 60 minutes post-exercise, SBP was lower in the 30% vs. 3% MVIC (p = 0.006). There was no difference for the other variables (p > 0.05). In study 2, IHT reduced SBP and HR in both trained groups (PHG and HG). DBP and mean BP decreased only in HG (p < 0.05). Reductions in pressure levels induced by IHT were maintained during the period without IHG exercise. There was an inverse association of ΔTrolox/TBARS and Δlactate in relation to ΔSBP (p < 0.05). ΔTBARS was positively associated with reductions in DBP and HR after IHT (p < 0.05). IHT induced increase in NO- concentrations (p < 0.05). The Δ increase in absolute handgrip strength was associated with the reduction of ΔSBP, ΔDBP, ΔHR and with increase in ΔTrolox/TBARS and ΔNO- after IHT (p < 0.05). In conclusion, study 1 demonstrated that IHG exercise induced postisometric exercise hypotension in hypertensive elderly, with no association with lactate and NO- concentrations. In study 2, IHT also induced a reduction in BP and HR levels in prehypertensive and hypertensive elderly subjects. Endotheliumdependent flow mediated vasodilation and improvement in the redox state may be the possible mechanisms involved.O objetivo deste estudo foi verificar o efeito agudo e crônico do exercício isométrico de preensão manual (EIPM) sobre as variáveis hemodinâmicas e bioquímicas em idosos pré-hipertensos e hipertensos. Foram realizados dois estudos: 1º Dez idosos hipertensos (♀ = 7), 73,2 ± 2,2 anos, 13,2 ± 3,1 anos de hipertensão, pressão arterial sistólica (PAS) 135,1 ± 6,5 mm Hg e pressão arterial diastólica (PAD) 76,6 ± 3,4 mm Hg foram submetidos a duas sessões agudas, uma controle a 3% e outra a 30% da contração voluntária isométrica máxima (CVIM) utilizando um dinamômetro de preensão manual hidráulico (Jamar, IL, USA). Os participantes completaram oito séries de um minuto de contração isométrica, bilateralmente, com pausa de um minuto. A pressão arterial (PA) e a frequência cardíaca (FC) foram mensuradas em repouso e 1, 5, 10, 15, 30, 45 e 60- min pós-exercício. O lactato sanguíneo e o óxido nítrico (NO-) salivar foram coletados em repouso, 0, 30 e 60- min pós-exercício. 2º Trinta e três idosos (♀ = 15), 75,6 ± 1,2 anos, foram divididos em 3 grupos: controle hipertenso (GC, n = 11), pré-hipertenso (GPH, n = 10) e hipertenso (GH, n = 12). O treinamento isométrico de preensão manual (TIPM) foi realizado durante 8 semanas, 3 vezes por semana em dias não consecutivos. A intensidade e o volume do TIPM foram os mesmos do estudo 1. Houve um período sem exercício após o TIPM de 4 semanas. As variáveis antropométricas e bioquímicas foram avaliadas pré e pós- TIPM. As variáveis hemodinâmicas e neuromusculares foram mensuradas antes, durante e após o TIPM. No estudo 1 houve uma redução da PAS após a sessão de 30% CVIM a partir do 10º min pós-exercício (p < 0,05). Aos 60 minutos pósexercício, a PAS foi menor na sessão 30% vs. 3% CVIM (p = 0,006). Não houve diferença para as demais variáveis (p > 0,05). No estudo 2, o TIPM reduziu a PAS e a FC em ambos os grupos treinados (GPH e GH). A PAD e a PA média diminuíram apenas no GH (p < 0,05). As reduções dos níveis pressóricos induzidas pelo TIPM foram mantidas durante o período sem o EIPM. Verificou-se uma associação inversa do ΔTrolox/TBARS e Δlactato em relação ao ΔPAS (p < 0,05). O ΔTBARS apresentou associação positiva com as reduções da PAD e da FC após o TIPM (p < 0,05). O TIPM induziu aumento nas concentrações do NO- plasmático (p < 0,05). O Δ de aumento na força de preensão manual absoluta foi associado com a redução do ΔPAS, ΔPAD, ΔFC e com o aumento no ΔTrolox/TBARS e ΔNO- após o TIPM (p < 0,05). Concluindo, o estudo 1 demonstrou que o EIPM induziu uma hipotensão pós-exercício isométrico em idosos hipertensos, sem associação com as concentrações de lactato e NO-. No estudo 2, o TIPM também induziu uma redução dos níveis pressóricos e da FC em idosos pré-hipertensos e hipertensos. vasodilatação mediada pelo fluxo dependente do endotélio e a melhora no estado redox podem ser os possíveis mecanismos envolvidos.Submitted by Sara Ribeiro (sara.ribeiro@ucb.br) on 2019-06-04T12:43:02Z No. of bitstreams: 1 LuizHumbertoRodriguesSouzaTese2019.pdf: 6040274 bytes, checksum: a438379b8bffad1cbd723172d289b555 (MD5)Approved for entry into archive by Sara Ribeiro (sara.ribeiro@ucb.br) on 2019-06-04T12:43:10Z (GMT) No. of bitstreams: 1 LuizHumbertoRodriguesSouzaTese2019.pdf: 6040274 bytes, checksum: a438379b8bffad1cbd723172d289b555 (MD5)Made available in DSpace on 2019-06-04T12:43:10Z (GMT). No. of bitstreams: 1 LuizHumbertoRodriguesSouzaTese2019.pdf: 6040274 bytes, checksum: a438379b8bffad1cbd723172d289b555 (MD5) Previous issue date: 2019-02-26application/pdfhttps://bdtd.ucb.br:8443/jspui/retrieve/6486/LuizHumbertoRodriguesSouzaTese2019.pdf.jpgporUniversidade Católica de BrasíliaPrograma Stricto Sensu em Educação FísicaUCBBrasilEscola de Saúde e MedicinaHipertensãoHemodinâmicaEnvelhecimentoPreensão manualEstresse oxidativoOxidative stressHemodynamicHypertensionHandgripAgingCNPQ::CIENCIAS DA SAUDE::EDUCACAO FISICAEfeitos agudos e crônicos do exercício isométrico de preensão manual nas variáveis hemodinâmicas, neuromusculares e bioquímicas em idosos institucionalizadosinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/doctoralThesisinfo:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da UCBinstname:Universidade Católica de Brasíliainstacron:UCBTHUMBNAILLuizHumbertoRodriguesSouzaTese2019.pdf.jpgLuizHumbertoRodriguesSouzaTese2019.pdf.jpgimage/jpeg6059https://bdtd.ucb.br:8443/jspui/bitstream/tede/2598/4/LuizHumbertoRodriguesSouzaTese2019.pdf.jpg16d704d1e0fcd47accbc44bcece934ceMD54TEXTLuizHumbertoRodriguesSouzaTese2019.pdf.txtLuizHumbertoRodriguesSouzaTese2019.pdf.txttext/plain219834https://bdtd.ucb.br:8443/jspui/bitstream/tede/2598/3/LuizHumbertoRodriguesSouzaTese2019.pdf.txteaede97a47eaac1d05dc3120cf406b33MD53ORIGINALLuizHumbertoRodriguesSouzaTese2019.pdfLuizHumbertoRodriguesSouzaTese2019.pdfapplication/pdf6040274https://bdtd.ucb.br:8443/jspui/bitstream/tede/2598/2/LuizHumbertoRodriguesSouzaTese2019.pdfa438379b8bffad1cbd723172d289b555MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-81831https://bdtd.ucb.br:8443/jspui/bitstream/tede/2598/1/license.txtd7d5e5ec75089f122abe937645a56120MD51tede/2598oai:bdtd.ucb.br:tede/25982019-06-05 01:05:38.779Biblioteca Digital de Dissertações da Universidade Católica de Brasília - UCBsdi@ucb.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 |
dc.title.por.fl_str_mv |
Efeitos agudos e crônicos do exercício isométrico de preensão manual nas variáveis hemodinâmicas, neuromusculares e bioquímicas em idosos institucionalizados |
title |
Efeitos agudos e crônicos do exercício isométrico de preensão manual nas variáveis hemodinâmicas, neuromusculares e bioquímicas em idosos institucionalizados |
spellingShingle |
Efeitos agudos e crônicos do exercício isométrico de preensão manual nas variáveis hemodinâmicas, neuromusculares e bioquímicas em idosos institucionalizados Souza, Luiz Humberto Rodrigues Hipertensão Hemodinâmica Envelhecimento Preensão manual Estresse oxidativo Oxidative stress Hemodynamic Hypertension Handgrip Aging CNPQ::CIENCIAS DA SAUDE::EDUCACAO FISICA |
title_short |
Efeitos agudos e crônicos do exercício isométrico de preensão manual nas variáveis hemodinâmicas, neuromusculares e bioquímicas em idosos institucionalizados |
title_full |
Efeitos agudos e crônicos do exercício isométrico de preensão manual nas variáveis hemodinâmicas, neuromusculares e bioquímicas em idosos institucionalizados |
title_fullStr |
Efeitos agudos e crônicos do exercício isométrico de preensão manual nas variáveis hemodinâmicas, neuromusculares e bioquímicas em idosos institucionalizados |
title_full_unstemmed |
Efeitos agudos e crônicos do exercício isométrico de preensão manual nas variáveis hemodinâmicas, neuromusculares e bioquímicas em idosos institucionalizados |
title_sort |
Efeitos agudos e crônicos do exercício isométrico de preensão manual nas variáveis hemodinâmicas, neuromusculares e bioquímicas em idosos institucionalizados |
author |
Souza, Luiz Humberto Rodrigues |
author_facet |
Souza, Luiz Humberto Rodrigues |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Moraes, Milton Rocha de |
dc.contributor.advisor1Lattes.fl_str_mv |
http://lattes.cnpq.br/1690322593621016 |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/7231951956450623 |
dc.contributor.author.fl_str_mv |
Souza, Luiz Humberto Rodrigues |
contributor_str_mv |
Moraes, Milton Rocha de |
dc.subject.por.fl_str_mv |
Hipertensão Hemodinâmica Envelhecimento Preensão manual Estresse oxidativo |
topic |
Hipertensão Hemodinâmica Envelhecimento Preensão manual Estresse oxidativo Oxidative stress Hemodynamic Hypertension Handgrip Aging CNPQ::CIENCIAS DA SAUDE::EDUCACAO FISICA |
dc.subject.eng.fl_str_mv |
Oxidative stress Hemodynamic Hypertension Handgrip Aging |
dc.subject.cnpq.fl_str_mv |
CNPQ::CIENCIAS DA SAUDE::EDUCACAO FISICA |
dc.description.abstract.eng.fl_txt_mv |
The objective of this study was to verify the acute and chronic effect of isometric handgrip (IHG) exercise on the hemodynamic and biochemical variables in the prehypertensive and hypertensive elderly subjects. Two studies were performed: 1º Ten hypertensive elderly (♀ = 7), 73.2 ± 2.2 years, 13.2 ± 3.1 years of hypertension, systolic blood pressure (SBP) 135.1 ± 6.5 mm Hg and diastolic blood pressure (DBP) of 76.6 ± 3.4 mm Hg were submitted to two acute sessions, a 3% control and another to 30% of maximal isometric voluntary contraction (MIVC) using a handgrip hydraulic dynamometer (Jamar, IL, USA). Participants completed eight sets of one minute isometric contraction, bilaterally, with one-minute pause. Blood pressure (BP) and heart rate (HR) were measured at rest and at 1, 5, 10, 15, 30, 45 and 60 min postexercise. Blood lactate and salivary nitric oxide (NO-) were collected at rest, 0, 30 and 60 min after exercise. 2º Thirty-three elderly (♀ = 15), 75.6 ± 1.2 years, were divided into three groups: hypertensive control (CG, n = 11), prehypertensive (PHG, n = 10) and hypertensive (HG = 12). Isometric handgrip training (IHT) was performed for 8 weeks, 3 times a week on non-consecutive days. The intensity and volume of the IHT were the same as in study 1. There was a non-exercise period after the 4- week IHT. Anthropometric and biochemical variables were evaluated before and after IHT. Hemodynamic and neuromuscular variables were measured before, during and after IHT. In study 1 there was a reduction of SBP after the session of 30% MVIC from the 10th min post-exercise (p < 0.05). At 60 minutes post-exercise, SBP was lower in the 30% vs. 3% MVIC (p = 0.006). There was no difference for the other variables (p > 0.05). In study 2, IHT reduced SBP and HR in both trained groups (PHG and HG). DBP and mean BP decreased only in HG (p < 0.05). Reductions in pressure levels induced by IHT were maintained during the period without IHG exercise. There was an inverse association of ΔTrolox/TBARS and Δlactate in relation to ΔSBP (p < 0.05). ΔTBARS was positively associated with reductions in DBP and HR after IHT (p < 0.05). IHT induced increase in NO- concentrations (p < 0.05). The Δ increase in absolute handgrip strength was associated with the reduction of ΔSBP, ΔDBP, ΔHR and with increase in ΔTrolox/TBARS and ΔNO- after IHT (p < 0.05). In conclusion, study 1 demonstrated that IHG exercise induced postisometric exercise hypotension in hypertensive elderly, with no association with lactate and NO- concentrations. In study 2, IHT also induced a reduction in BP and HR levels in prehypertensive and hypertensive elderly subjects. Endotheliumdependent flow mediated vasodilation and improvement in the redox state may be the possible mechanisms involved. |
dc.description.abstract.por.fl_txt_mv |
O objetivo deste estudo foi verificar o efeito agudo e crônico do exercício isométrico de preensão manual (EIPM) sobre as variáveis hemodinâmicas e bioquímicas em idosos pré-hipertensos e hipertensos. Foram realizados dois estudos: 1º Dez idosos hipertensos (♀ = 7), 73,2 ± 2,2 anos, 13,2 ± 3,1 anos de hipertensão, pressão arterial sistólica (PAS) 135,1 ± 6,5 mm Hg e pressão arterial diastólica (PAD) 76,6 ± 3,4 mm Hg foram submetidos a duas sessões agudas, uma controle a 3% e outra a 30% da contração voluntária isométrica máxima (CVIM) utilizando um dinamômetro de preensão manual hidráulico (Jamar, IL, USA). Os participantes completaram oito séries de um minuto de contração isométrica, bilateralmente, com pausa de um minuto. A pressão arterial (PA) e a frequência cardíaca (FC) foram mensuradas em repouso e 1, 5, 10, 15, 30, 45 e 60- min pós-exercício. O lactato sanguíneo e o óxido nítrico (NO-) salivar foram coletados em repouso, 0, 30 e 60- min pós-exercício. 2º Trinta e três idosos (♀ = 15), 75,6 ± 1,2 anos, foram divididos em 3 grupos: controle hipertenso (GC, n = 11), pré-hipertenso (GPH, n = 10) e hipertenso (GH, n = 12). O treinamento isométrico de preensão manual (TIPM) foi realizado durante 8 semanas, 3 vezes por semana em dias não consecutivos. A intensidade e o volume do TIPM foram os mesmos do estudo 1. Houve um período sem exercício após o TIPM de 4 semanas. As variáveis antropométricas e bioquímicas foram avaliadas pré e pós- TIPM. As variáveis hemodinâmicas e neuromusculares foram mensuradas antes, durante e após o TIPM. No estudo 1 houve uma redução da PAS após a sessão de 30% CVIM a partir do 10º min pós-exercício (p < 0,05). Aos 60 minutos pósexercício, a PAS foi menor na sessão 30% vs. 3% CVIM (p = 0,006). Não houve diferença para as demais variáveis (p > 0,05). No estudo 2, o TIPM reduziu a PAS e a FC em ambos os grupos treinados (GPH e GH). A PAD e a PA média diminuíram apenas no GH (p < 0,05). As reduções dos níveis pressóricos induzidas pelo TIPM foram mantidas durante o período sem o EIPM. Verificou-se uma associação inversa do ΔTrolox/TBARS e Δlactato em relação ao ΔPAS (p < 0,05). O ΔTBARS apresentou associação positiva com as reduções da PAD e da FC após o TIPM (p < 0,05). O TIPM induziu aumento nas concentrações do NO- plasmático (p < 0,05). O Δ de aumento na força de preensão manual absoluta foi associado com a redução do ΔPAS, ΔPAD, ΔFC e com o aumento no ΔTrolox/TBARS e ΔNO- após o TIPM (p < 0,05). Concluindo, o estudo 1 demonstrou que o EIPM induziu uma hipotensão pós-exercício isométrico em idosos hipertensos, sem associação com as concentrações de lactato e NO-. No estudo 2, o TIPM também induziu uma redução dos níveis pressóricos e da FC em idosos pré-hipertensos e hipertensos. vasodilatação mediada pelo fluxo dependente do endotélio e a melhora no estado redox podem ser os possíveis mecanismos envolvidos. |
description |
The objective of this study was to verify the acute and chronic effect of isometric handgrip (IHG) exercise on the hemodynamic and biochemical variables in the prehypertensive and hypertensive elderly subjects. Two studies were performed: 1º Ten hypertensive elderly (♀ = 7), 73.2 ± 2.2 years, 13.2 ± 3.1 years of hypertension, systolic blood pressure (SBP) 135.1 ± 6.5 mm Hg and diastolic blood pressure (DBP) of 76.6 ± 3.4 mm Hg were submitted to two acute sessions, a 3% control and another to 30% of maximal isometric voluntary contraction (MIVC) using a handgrip hydraulic dynamometer (Jamar, IL, USA). Participants completed eight sets of one minute isometric contraction, bilaterally, with one-minute pause. Blood pressure (BP) and heart rate (HR) were measured at rest and at 1, 5, 10, 15, 30, 45 and 60 min postexercise. Blood lactate and salivary nitric oxide (NO-) were collected at rest, 0, 30 and 60 min after exercise. 2º Thirty-three elderly (♀ = 15), 75.6 ± 1.2 years, were divided into three groups: hypertensive control (CG, n = 11), prehypertensive (PHG, n = 10) and hypertensive (HG = 12). Isometric handgrip training (IHT) was performed for 8 weeks, 3 times a week on non-consecutive days. The intensity and volume of the IHT were the same as in study 1. There was a non-exercise period after the 4- week IHT. Anthropometric and biochemical variables were evaluated before and after IHT. Hemodynamic and neuromuscular variables were measured before, during and after IHT. In study 1 there was a reduction of SBP after the session of 30% MVIC from the 10th min post-exercise (p < 0.05). At 60 minutes post-exercise, SBP was lower in the 30% vs. 3% MVIC (p = 0.006). There was no difference for the other variables (p > 0.05). In study 2, IHT reduced SBP and HR in both trained groups (PHG and HG). DBP and mean BP decreased only in HG (p < 0.05). Reductions in pressure levels induced by IHT were maintained during the period without IHG exercise. There was an inverse association of ΔTrolox/TBARS and Δlactate in relation to ΔSBP (p < 0.05). ΔTBARS was positively associated with reductions in DBP and HR after IHT (p < 0.05). IHT induced increase in NO- concentrations (p < 0.05). The Δ increase in absolute handgrip strength was associated with the reduction of ΔSBP, ΔDBP, ΔHR and with increase in ΔTrolox/TBARS and ΔNO- after IHT (p < 0.05). In conclusion, study 1 demonstrated that IHG exercise induced postisometric exercise hypotension in hypertensive elderly, with no association with lactate and NO- concentrations. In study 2, IHT also induced a reduction in BP and HR levels in prehypertensive and hypertensive elderly subjects. Endotheliumdependent flow mediated vasodilation and improvement in the redox state may be the possible mechanisms involved. |
publishDate |
2019 |
dc.date.accessioned.fl_str_mv |
2019-06-04T12:43:10Z |
dc.date.issued.fl_str_mv |
2019-02-26 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/doctoralThesis |
status_str |
publishedVersion |
format |
doctoralThesis |
dc.identifier.citation.fl_str_mv |
SOUZA, Luiz Humberto Rodrigues. Efeitos agudos e crônicos do exercício isométrico de preensão manual nas variáveis hemodinâmicas, neuromusculares e bioquímicas em idosos institucionalizados. 2019. 139 f. Tese (Programa Stricto Sensu em Educação Física) - Universidade Católica de Brasília, Brasília, 2019. |
dc.identifier.uri.fl_str_mv |
https://bdtd.ucb.br:8443/jspui/handle/tede/2598 |
identifier_str_mv |
SOUZA, Luiz Humberto Rodrigues. Efeitos agudos e crônicos do exercício isométrico de preensão manual nas variáveis hemodinâmicas, neuromusculares e bioquímicas em idosos institucionalizados. 2019. 139 f. Tese (Programa Stricto Sensu em Educação Física) - Universidade Católica de Brasília, Brasília, 2019. |
url |
https://bdtd.ucb.br:8443/jspui/handle/tede/2598 |
dc.language.iso.fl_str_mv |
por |
language |
por |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Católica de Brasília |
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Programa Stricto Sensu em Educação Física |
dc.publisher.initials.fl_str_mv |
UCB |
dc.publisher.country.fl_str_mv |
Brasil |
dc.publisher.department.fl_str_mv |
Escola de Saúde e Medicina |
publisher.none.fl_str_mv |
Universidade Católica de Brasília |
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