Perfil epidemiologico das neoplasias do colo uterino (in situ e invasoras) diagnosticadas na cidade de goiânia: análise de 17 anos (1988-2004)
Ano de defesa: | 2010 |
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Autor(a) principal: | |
Orientador(a): | |
Banca de defesa: | |
Tipo de documento: | Dissertação |
Tipo de acesso: | Acesso aberto |
Idioma: | por |
Instituição de defesa: |
Universidade Federal de Goiás
|
Programa de Pós-Graduação: |
Mestrado em Ciências da Saúde
|
Departamento: |
Ciências da Saúde - Medicina
|
País: |
BR
|
Palavras-chave em Português: | |
Palavras-chave em Inglês: | |
Área do conhecimento CNPq: | |
Link de acesso: | http://repositorio.bc.ufg.br/tede/handle/tde/1731 |
Resumo: | Determine the epidemiological profile of in situ and invasive neoplasias of the uterus cervix in Goiânia during the period from 1988 to 2004. Methodology: The cases were identified in the Population Base Register of Cancer database of Goiânia. The studied variables were: age, histological type, extension of the disease and mortality. Analysis was done by central tendency in which the incidence rates were calculated by age, extension of the disease using Census population data and the standard population of Segi; for the mortality analysis the data were extracted from Mortality Information System. Results: We identified 4446 cases of in situ and invasive neoplasias of the uterus from the period of 1988 to 2004. Histopathology was used in 91,9% of the cases; average age was 40 years old for the in situ neoplasias and 52 years for the invasive ones (DP ± 13 and 14 years old, respectively). There were 2213 (58,28%) in situ cases, 1603 invasives (41,8%) and, in 633 cases (14,2%), it was not possible to verify their extension. The annual rate of percentage change (AAPC) for the in situ incidence was 13.08% (IC 95% 9.75 16.50; p<0.0000) per year and1.27% (IC95% -1.74 4.37; p<0.3862) for the invasive cases. The standard mortality rate was 12.2 and 8.2 per 100,000 in 1988 and 2004 respectively, with an AAPC of -3.02 (IC95% -5,36 -0,62; p<0,0172). Squamous cell carcinoma was found to be the predominant histologic type. A reduction of the Adenocarcinoma incidence in situ was not found nor was found a significant change of the Adenocarcinoma invasive; the squamous invasive cancer did present a considerable reduction of 2,85 per year. Conclusion: It was observed that the most frequent invasive tumors were the squamous cell carcinomas and Adenocarcinomas. Data did not demonstrate a rise in the diagnosis of invasive neoplasia, although there occurred an increase of diagnoses of in situ neoplasias. Mortality has demonstrated a tendency of reduction, suggesting that improvements of the tracking programs have changed the incidence or uterine cancer, though it has not yet accomplished all its objectives. Keywords: cervical cancer, uterus, epidemiology, frequency, extension, incidence, Goiânia, Brazil. |
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MOREIRA, Marise Amaral Rebouçashttp://lattes.cnpq.br/6390358577348486http://lattes.cnpq.br/9184054265912992ALMEIDA, Fábio Marques de2014-07-29T15:29:11Z2012-02-242010-10-28ALMEIDA, Fábio Marques de. Epidemiological profile of cancer of the cervix (in situ and invasive) diagnosed in the city of goiânia: analysis of 17 years (1988-2004). 2010. 126 f. Dissertação (Mestrado em Ciências da Saúde - Medicina) - Universidade Federal de Goiás, Goiânia, 2010.http://repositorio.bc.ufg.br/tede/handle/tde/1731Determine the epidemiological profile of in situ and invasive neoplasias of the uterus cervix in Goiânia during the period from 1988 to 2004. Methodology: The cases were identified in the Population Base Register of Cancer database of Goiânia. The studied variables were: age, histological type, extension of the disease and mortality. Analysis was done by central tendency in which the incidence rates were calculated by age, extension of the disease using Census population data and the standard population of Segi; for the mortality analysis the data were extracted from Mortality Information System. Results: We identified 4446 cases of in situ and invasive neoplasias of the uterus from the period of 1988 to 2004. Histopathology was used in 91,9% of the cases; average age was 40 years old for the in situ neoplasias and 52 years for the invasive ones (DP ± 13 and 14 years old, respectively). There were 2213 (58,28%) in situ cases, 1603 invasives (41,8%) and, in 633 cases (14,2%), it was not possible to verify their extension. The annual rate of percentage change (AAPC) for the in situ incidence was 13.08% (IC 95% 9.75 16.50; p<0.0000) per year and1.27% (IC95% -1.74 4.37; p<0.3862) for the invasive cases. The standard mortality rate was 12.2 and 8.2 per 100,000 in 1988 and 2004 respectively, with an AAPC of -3.02 (IC95% -5,36 -0,62; p<0,0172). Squamous cell carcinoma was found to be the predominant histologic type. A reduction of the Adenocarcinoma incidence in situ was not found nor was found a significant change of the Adenocarcinoma invasive; the squamous invasive cancer did present a considerable reduction of 2,85 per year. Conclusion: It was observed that the most frequent invasive tumors were the squamous cell carcinomas and Adenocarcinomas. Data did not demonstrate a rise in the diagnosis of invasive neoplasia, although there occurred an increase of diagnoses of in situ neoplasias. Mortality has demonstrated a tendency of reduction, suggesting that improvements of the tracking programs have changed the incidence or uterine cancer, though it has not yet accomplished all its objectives. Keywords: cervical cancer, uterus, epidemiology, frequency, extension, incidence, Goiânia, Brazil.Determinar o perfil de incidência e mortalidade das mulheres portadoras de neoplasias (in situ e invasoras) do colo uterino, na Cidade de Goiânia, no período de 1988 a 2004. Metodologia: Estudo de base populacional dos casos coletados no banco de dados do Registro de Câncer de Base Populacional de Goiânia. As variáveis estudadas foram: idade, tipo histológico, extensão da doença. A análise foi feita pela tendência central, onde foram calculadas as taxas de incidência por idade e pela extensão da doença, utilizando-se a população censitária e intercensitária, coletada do Instituto Brasileiro de Geografia e Estatística, e a população padrão de Segi; e para a análise de mortalidade os dados foram extraídos do Sistema de Informação sobre Mortalidade. Resultados: Nos resultados foram identificados 4446 casos de neoplasias do colo uterino (in situ e invasoras), no período de 1988 a 2004. A base diagnóstica empregada foi a histopatológica em 91,9% dos casos e o pico de incidência para as neoplasias in situ foi de 30 anos de idade e para as invasoras de 45 anos. O número de casos in situ foi de 2213 (58,28%), de invasores 1603 (41,8%) e, em 633 casos (14,2%), não foi possível identificar a sua extensão. A taxa de mudança percentual anual (AAPC) para a incidência das neoplasias in situ foi de 13,08% (p<0,001) ao ano e de 1,27% (p=0,386) para as invasoras. A taxa padronizada de mortalidade foi de 12,2 e de 8,2/10000, em 1988 e 2004, respectivamente, e a AAPC de -3,02% (p=0,017) ao ano. Verificou-se que o carcinoma espinocelular (CEC) foi o tipo histológico predominante e que o CEC invasor e o adenocarcinoma invasor não apresentaram tendência de redução. Conclusão: Não houve redução significativa na incidência do câncer de colo uterino invasor no período analisado; entretanto, a taxa de incidência das lesões in situ aumentou significativamente no mesmo período. O adenocarcinoma e o CEC provavelmente permaneceram estáveis nos últimos 10 anos. Quanto à mortalidade foi demonstrada uma tendência de queda. Esses resultados sugerem que a melhoria dos programas de rastreamento tem modificado a evolução do câncer do colo uterino, embora nem todos os objetivos tenham sido atingidos. Unitermos: Neoplasias do colo uterino, epidemiologia, tendências, estudo de séries temporais, Goiânia, Brasil.Made available in DSpace on 2014-07-29T15:29:11Z (GMT). No. of bitstreams: 1 Dissertacao Mestrado Fabio Marques de Almeida.pdf: 2048558 bytes, checksum: 5dff3bcad8868258e748980ec17d407d (MD5) Previous issue date: 2010-10-28application/pdfhttp://repositorio.bc.ufg.br/TEDE/retrieve/4579/Dissertacao%20Mestrado%20Fabio%20Marques%20de%20Almeida.pdf.jpgporUniversidade Federal de GoiásMestrado em Ciências da SaúdeUFGBRCiências da Saúde - Medicinacancer do colo uterinoepidemiologiafrequenciaextensãoincidenciagoianiagoiascancer of the cervixepidemiologyfrequencyextensionincidencelondongrooveCNPQ::CIENCIAS DA SAUDEPerfil epidemiologico das neoplasias do colo uterino (in situ e invasoras) diagnosticadas na cidade de goiânia: análise de 17 anos (1988-2004)Epidemiological profile of cancer of the cervix (in situ and invasive) diagnosed in the city of goiânia: analysis of 17 years (1988-2004)info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFGinstname:Universidade Federal de Goiás (UFG)instacron:UFGORIGINALDissertacao Mestrado Fabio Marques de Almeida.pdfapplication/pdf2048558http://repositorio.bc.ufg.br/tede/bitstreams/55b24d5b-c54a-47aa-8d18-afc2de834fc9/download5dff3bcad8868258e748980ec17d407dMD51THUMBNAILDissertacao Mestrado Fabio Marques de Almeida.pdf.jpgDissertacao Mestrado Fabio Marques de Almeida.pdf.jpgGenerated Thumbnailimage/jpeg4256http://repositorio.bc.ufg.br/tede/bitstreams/c6e70d66-4986-4c78-acd8-b9285f3948f3/download81baba4176aef3b40cefd71ec02f82c0MD52tde/17312014-07-30 03:15:03.311open.accessoai:repositorio.bc.ufg.br:tde/1731http://repositorio.bc.ufg.br/tedeRepositório InstitucionalPUBhttp://repositorio.bc.ufg.br/oai/requesttasesdissertacoes.bc@ufg.bropendoar:2014-07-30T06:15:03Repositório Institucional da UFG - Universidade Federal de Goiás (UFG)false |
dc.title.por.fl_str_mv |
Perfil epidemiologico das neoplasias do colo uterino (in situ e invasoras) diagnosticadas na cidade de goiânia: análise de 17 anos (1988-2004) |
dc.title.alternative.eng.fl_str_mv |
Epidemiological profile of cancer of the cervix (in situ and invasive) diagnosed in the city of goiânia: analysis of 17 years (1988-2004) |
title |
Perfil epidemiologico das neoplasias do colo uterino (in situ e invasoras) diagnosticadas na cidade de goiânia: análise de 17 anos (1988-2004) |
spellingShingle |
Perfil epidemiologico das neoplasias do colo uterino (in situ e invasoras) diagnosticadas na cidade de goiânia: análise de 17 anos (1988-2004) ALMEIDA, Fábio Marques de cancer do colo uterino epidemiologia frequencia extensão incidencia goiania goias cancer of the cervix epidemiology frequency extension incidence london groove CNPQ::CIENCIAS DA SAUDE |
title_short |
Perfil epidemiologico das neoplasias do colo uterino (in situ e invasoras) diagnosticadas na cidade de goiânia: análise de 17 anos (1988-2004) |
title_full |
Perfil epidemiologico das neoplasias do colo uterino (in situ e invasoras) diagnosticadas na cidade de goiânia: análise de 17 anos (1988-2004) |
title_fullStr |
Perfil epidemiologico das neoplasias do colo uterino (in situ e invasoras) diagnosticadas na cidade de goiânia: análise de 17 anos (1988-2004) |
title_full_unstemmed |
Perfil epidemiologico das neoplasias do colo uterino (in situ e invasoras) diagnosticadas na cidade de goiânia: análise de 17 anos (1988-2004) |
title_sort |
Perfil epidemiologico das neoplasias do colo uterino (in situ e invasoras) diagnosticadas na cidade de goiânia: análise de 17 anos (1988-2004) |
author |
ALMEIDA, Fábio Marques de |
author_facet |
ALMEIDA, Fábio Marques de |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
MOREIRA, Marise Amaral Rebouças |
dc.contributor.advisor1Lattes.fl_str_mv |
http://lattes.cnpq.br/6390358577348486 |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/9184054265912992 |
dc.contributor.author.fl_str_mv |
ALMEIDA, Fábio Marques de |
contributor_str_mv |
MOREIRA, Marise Amaral Rebouças |
dc.subject.por.fl_str_mv |
cancer do colo uterino epidemiologia frequencia extensão incidencia goiania goias |
topic |
cancer do colo uterino epidemiologia frequencia extensão incidencia goiania goias cancer of the cervix epidemiology frequency extension incidence london groove CNPQ::CIENCIAS DA SAUDE |
dc.subject.eng.fl_str_mv |
cancer of the cervix epidemiology frequency extension incidence london groove |
dc.subject.cnpq.fl_str_mv |
CNPQ::CIENCIAS DA SAUDE |
description |
Determine the epidemiological profile of in situ and invasive neoplasias of the uterus cervix in Goiânia during the period from 1988 to 2004. Methodology: The cases were identified in the Population Base Register of Cancer database of Goiânia. The studied variables were: age, histological type, extension of the disease and mortality. Analysis was done by central tendency in which the incidence rates were calculated by age, extension of the disease using Census population data and the standard population of Segi; for the mortality analysis the data were extracted from Mortality Information System. Results: We identified 4446 cases of in situ and invasive neoplasias of the uterus from the period of 1988 to 2004. Histopathology was used in 91,9% of the cases; average age was 40 years old for the in situ neoplasias and 52 years for the invasive ones (DP ± 13 and 14 years old, respectively). There were 2213 (58,28%) in situ cases, 1603 invasives (41,8%) and, in 633 cases (14,2%), it was not possible to verify their extension. The annual rate of percentage change (AAPC) for the in situ incidence was 13.08% (IC 95% 9.75 16.50; p<0.0000) per year and1.27% (IC95% -1.74 4.37; p<0.3862) for the invasive cases. The standard mortality rate was 12.2 and 8.2 per 100,000 in 1988 and 2004 respectively, with an AAPC of -3.02 (IC95% -5,36 -0,62; p<0,0172). Squamous cell carcinoma was found to be the predominant histologic type. A reduction of the Adenocarcinoma incidence in situ was not found nor was found a significant change of the Adenocarcinoma invasive; the squamous invasive cancer did present a considerable reduction of 2,85 per year. Conclusion: It was observed that the most frequent invasive tumors were the squamous cell carcinomas and Adenocarcinomas. Data did not demonstrate a rise in the diagnosis of invasive neoplasia, although there occurred an increase of diagnoses of in situ neoplasias. Mortality has demonstrated a tendency of reduction, suggesting that improvements of the tracking programs have changed the incidence or uterine cancer, though it has not yet accomplished all its objectives. Keywords: cervical cancer, uterus, epidemiology, frequency, extension, incidence, Goiânia, Brazil. |
publishDate |
2010 |
dc.date.issued.fl_str_mv |
2010-10-28 |
dc.date.available.fl_str_mv |
2012-02-24 |
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2014-07-29T15:29:11Z |
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info:eu-repo/semantics/publishedVersion |
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masterThesis |
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publishedVersion |
dc.identifier.citation.fl_str_mv |
ALMEIDA, Fábio Marques de. Epidemiological profile of cancer of the cervix (in situ and invasive) diagnosed in the city of goiânia: analysis of 17 years (1988-2004). 2010. 126 f. Dissertação (Mestrado em Ciências da Saúde - Medicina) - Universidade Federal de Goiás, Goiânia, 2010. |
dc.identifier.uri.fl_str_mv |
http://repositorio.bc.ufg.br/tede/handle/tde/1731 |
identifier_str_mv |
ALMEIDA, Fábio Marques de. Epidemiological profile of cancer of the cervix (in situ and invasive) diagnosed in the city of goiânia: analysis of 17 years (1988-2004). 2010. 126 f. Dissertação (Mestrado em Ciências da Saúde - Medicina) - Universidade Federal de Goiás, Goiânia, 2010. |
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http://repositorio.bc.ufg.br/tede/handle/tde/1731 |
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por |
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Universidade Federal de Goiás |
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Mestrado em Ciências da Saúde |
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UFG |
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BR |
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Ciências da Saúde - Medicina |
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Universidade Federal de Goiás |
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