Biocerâmica de fosfato de cálcio nano-estruturado micro-macro porosa em grânulos de absorção rápida no preenchimento de defeito crítico em radio de coelhos (Oryctolagus cuniculus)

Detalhes bibliográficos
Ano de defesa: 2013
Autor(a) principal: Jessica Alejandra Castro Varon
Orientador(a): Não Informado pela instituição
Banca de defesa: Não Informado pela instituição
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Federal de Minas Gerais
Programa de Pós-Graduação: Não Informado pela instituição
Departamento: Não Informado pela instituição
País: Não Informado pela instituição
Palavras-chave em Português:
Fosfato de cálcio
Materiais biomédicos
Ortopedia veterinaria
Coelho Cirurgia
Ossos Regeneração
coelho
defeito critico
biocerâmica
radio
Link de acesso: https://hdl.handle.net/1843/SMOC-9HXP2S
Resumo: The objective of this study was to evaluate by radiography , histology and bone densitometry the effect of HA / TCP granules for rapid absorption in critical bone defect in radio rabbits ( Oryctolagus cuniculus ) . 35 rabbits were used in which a critical defect was performed on left and right radios . The animals were divided into GI , GII autograft and HA / TCP granules for rapid absorption . Radiographic examinations were made before surgery, immediately after the eighth , 15, 30 , 45, 60 , 90 and 120 days. At the end of each period, the animals were euthanized by anesthetic overdose and radios were harvested for histological assessment and densitometry . There was a significant difference between the treated and control groups when comparing bone mineral density obtained over the entire study period . It was verified histologically formation of a vascular network of the pores of bioceramic from the first time rating (eight days). Formation of primary bone tissue and trabeculae from preexisting bone tissue , were identified from the 30 days after implantation . At 60 days , the last time histological evaluation , we observed the presence of bone matrix from preexisting bone segments , featuring the centripetal bone formation . The bioceramic calcium phosphate nano - structured micro - macro porous granules for rapid absorption allows cell proliferation and invasion and thus promotes bone regeneration , thus becoming a suitable implant for filling bone defects criticism
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spelling Biocerâmica de fosfato de cálcio nano-estruturado micro-macro porosa em grânulos de absorção rápida no preenchimento de defeito crítico em radio de coelhos (Oryctolagus cuniculus)Fosfato de cálcioMateriais biomédicosOrtopedia veterinariaCoelho CirurgiaOssos Regeneraçãocoelhodefeito criticobiocerâmicaradioThe objective of this study was to evaluate by radiography , histology and bone densitometry the effect of HA / TCP granules for rapid absorption in critical bone defect in radio rabbits ( Oryctolagus cuniculus ) . 35 rabbits were used in which a critical defect was performed on left and right radios . The animals were divided into GI , GII autograft and HA / TCP granules for rapid absorption . Radiographic examinations were made before surgery, immediately after the eighth , 15, 30 , 45, 60 , 90 and 120 days. At the end of each period, the animals were euthanized by anesthetic overdose and radios were harvested for histological assessment and densitometry . There was a significant difference between the treated and control groups when comparing bone mineral density obtained over the entire study period . It was verified histologically formation of a vascular network of the pores of bioceramic from the first time rating (eight days). Formation of primary bone tissue and trabeculae from preexisting bone tissue , were identified from the 30 days after implantation . At 60 days , the last time histological evaluation , we observed the presence of bone matrix from preexisting bone segments , featuring the centripetal bone formation . The bioceramic calcium phosphate nano - structured micro - macro porous granules for rapid absorption allows cell proliferation and invasion and thus promotes bone regeneration , thus becoming a suitable implant for filling bone defects criticismUniversidade Federal de Minas Gerais2019-08-14T02:31:56Z2025-09-09T01:06:30Z2019-08-14T02:31:56Z2013-01-25info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisapplication/pdfhttps://hdl.handle.net/1843/SMOC-9HXP2SJessica Alejandra Castro Varoninfo:eu-repo/semantics/openAccessporreponame:Repositório Institucional da UFMGinstname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMG2025-09-09T01:06:30Zoai:repositorio.ufmg.br:1843/SMOC-9HXP2SRepositório InstitucionalPUBhttps://repositorio.ufmg.br/oairepositorio@ufmg.bropendoar:2025-09-09T01:06:30Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)false
dc.title.none.fl_str_mv Biocerâmica de fosfato de cálcio nano-estruturado micro-macro porosa em grânulos de absorção rápida no preenchimento de defeito crítico em radio de coelhos (Oryctolagus cuniculus)
title Biocerâmica de fosfato de cálcio nano-estruturado micro-macro porosa em grânulos de absorção rápida no preenchimento de defeito crítico em radio de coelhos (Oryctolagus cuniculus)
spellingShingle Biocerâmica de fosfato de cálcio nano-estruturado micro-macro porosa em grânulos de absorção rápida no preenchimento de defeito crítico em radio de coelhos (Oryctolagus cuniculus)
Jessica Alejandra Castro Varon
Fosfato de cálcio
Materiais biomédicos
Ortopedia veterinaria
Coelho Cirurgia
Ossos Regeneração
coelho
defeito critico
biocerâmica
radio
title_short Biocerâmica de fosfato de cálcio nano-estruturado micro-macro porosa em grânulos de absorção rápida no preenchimento de defeito crítico em radio de coelhos (Oryctolagus cuniculus)
title_full Biocerâmica de fosfato de cálcio nano-estruturado micro-macro porosa em grânulos de absorção rápida no preenchimento de defeito crítico em radio de coelhos (Oryctolagus cuniculus)
title_fullStr Biocerâmica de fosfato de cálcio nano-estruturado micro-macro porosa em grânulos de absorção rápida no preenchimento de defeito crítico em radio de coelhos (Oryctolagus cuniculus)
title_full_unstemmed Biocerâmica de fosfato de cálcio nano-estruturado micro-macro porosa em grânulos de absorção rápida no preenchimento de defeito crítico em radio de coelhos (Oryctolagus cuniculus)
title_sort Biocerâmica de fosfato de cálcio nano-estruturado micro-macro porosa em grânulos de absorção rápida no preenchimento de defeito crítico em radio de coelhos (Oryctolagus cuniculus)
author Jessica Alejandra Castro Varon
author_facet Jessica Alejandra Castro Varon
author_role author
dc.contributor.author.fl_str_mv Jessica Alejandra Castro Varon
dc.subject.por.fl_str_mv Fosfato de cálcio
Materiais biomédicos
Ortopedia veterinaria
Coelho Cirurgia
Ossos Regeneração
coelho
defeito critico
biocerâmica
radio
topic Fosfato de cálcio
Materiais biomédicos
Ortopedia veterinaria
Coelho Cirurgia
Ossos Regeneração
coelho
defeito critico
biocerâmica
radio
description The objective of this study was to evaluate by radiography , histology and bone densitometry the effect of HA / TCP granules for rapid absorption in critical bone defect in radio rabbits ( Oryctolagus cuniculus ) . 35 rabbits were used in which a critical defect was performed on left and right radios . The animals were divided into GI , GII autograft and HA / TCP granules for rapid absorption . Radiographic examinations were made before surgery, immediately after the eighth , 15, 30 , 45, 60 , 90 and 120 days. At the end of each period, the animals were euthanized by anesthetic overdose and radios were harvested for histological assessment and densitometry . There was a significant difference between the treated and control groups when comparing bone mineral density obtained over the entire study period . It was verified histologically formation of a vascular network of the pores of bioceramic from the first time rating (eight days). Formation of primary bone tissue and trabeculae from preexisting bone tissue , were identified from the 30 days after implantation . At 60 days , the last time histological evaluation , we observed the presence of bone matrix from preexisting bone segments , featuring the centripetal bone formation . The bioceramic calcium phosphate nano - structured micro - macro porous granules for rapid absorption allows cell proliferation and invasion and thus promotes bone regeneration , thus becoming a suitable implant for filling bone defects criticism
publishDate 2013
dc.date.none.fl_str_mv 2013-01-25
2019-08-14T02:31:56Z
2019-08-14T02:31:56Z
2025-09-09T01:06:30Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://hdl.handle.net/1843/SMOC-9HXP2S
url https://hdl.handle.net/1843/SMOC-9HXP2S
dc.language.iso.fl_str_mv por
language por
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Federal de Minas Gerais
publisher.none.fl_str_mv Universidade Federal de Minas Gerais
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFMG
instname:Universidade Federal de Minas Gerais (UFMG)
instacron:UFMG
instname_str Universidade Federal de Minas Gerais (UFMG)
instacron_str UFMG
institution UFMG
reponame_str Repositório Institucional da UFMG
collection Repositório Institucional da UFMG
repository.name.fl_str_mv Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)
repository.mail.fl_str_mv repositorio@ufmg.br
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