Avaliação osteossonográfica da densidade mineral de crianças e adolescentes com doença celíaca

• Ano de defesa: 2014
• Autor(a) principal: Paula Valladares Povoa Guerra
• Tipo de documento: Tese
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de Minas Gerais; UFMG
• Palavras-chave em Português: Osteossonografia; Doença celíaca; Osteopatia; Crianças; Composição corporal; Osteogênese imperfeita; Enteropatias; Osteoprotegerina; Hipersensibilidade alimentar; Osteopontina; Criança; Adolescente
• Link de acesso: http://hdl.handle.net/1843/BUOS-9UHQ88

Introduction: The most gain in bone mass occurs during childhood and adolescence. Celiac disease (CD) may impair bone mineralization. The gluten-free diet prevents and / or reduces this morbidity in these patients. Objective: Compare, through quantitative ultrasound of phalanxes, bone density of children and adolescents with CD on a gluten-free diet and controls. Methods: 31 participants with a diagnosis of CD on a gluten-free diet for at least one year and 31 controls were selected. Patients using drugs, vitamins and dietary supplements were excluded. All participants underwent medical, nutritional, biochemical avaliation and quantitative ultrasound. Results: Due to positive transglutaminase antibody in seven patients with CD, a third group was created - CD without treatment. There were no difference between all groups in relation to gender, calcium intake, sun exposure, physical activity and anthropometric data. Calcium intake was low for all groups. There were no statistical differences between all groups in laboratory tests (calcium, phosphorus and parathyroid hormone), as well as data such as amplitude dependent speed of sound and bone transmission time by quantitative ultrasound. Conclusion: Children and adolescents with CD, on a gluten-free diet for at least one year, have normal bone mineral density assessed by quantitative ultrasound.