Câncer de próstata : incidência, mortalidade e sobrevida de residentes em Cuiabá e Várzea Grande

Detalhes bibliográficos
Ano de defesa: 2022
Autor(a) principal: Evangelista, Flávio de Macêdo
Orientador(a): Não Informado pela instituição
Banca de defesa: Não Informado pela instituição
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Federal de Mato Grosso
Brasil
Instituto de Saúde Coletiva (ISC)
UFMT CUC - Cuiabá
Programa de Pós-Graduação em Saúde Coletiva
Programa de Pós-Graduação: Não Informado pela instituição
Departamento: Não Informado pela instituição
País: Não Informado pela instituição
Palavras-chave em Português:
Link de acesso: http://ri.ufmt.br/handle/1/5894
Resumo: Prostate cancer was the second most frequent and the fifth leading cause of cancer death among men in 2020 worldwide. It is important to know the epidemiological picture of cancer so that we can advance in prevention and control. Objective: To analyze the incidence, mortality and survival from prostate cancer in men living in Cuiabá and Várzea Grande, from 2000 to 2016. Methods: Study carried out in the cities of Cuiabá and Várzea Grande that analyzed the incidence, mortality and survival of prostate cancer. Data were obtained through the Population-Based Cancer Registry (RCBP) and Mortality Information System (SIM), from an extension project developed at the Instituto de Saúde Coletiva of the Federal University of Mato Grosso and entitled “Cancer and Its Diseases”. Associated Factors: Analysis of Population-Based and Hospital Registry of Mato Grosso”. Incidence and mortality rates for prostate cancer were calculated by year (2000 to 2016) and by age group, dividing the number of new cases by the population and multiplying by 100,000 inhabitants. Joinpoint method, calculating the annual percentage change (APC) and Average Annual Percentage Change (AAPC) using the Jointpoint Regression Program software. To calculate survival, a probabilistic relationship was performed between the cases registered in the RCBP between 2008 and 2012 and in the SIM between 2008 and 2017, using the RecLink III software. The Kaplan-Meier estimator method was used to analyze the survival curves and the semiparametric Cox proportional hazards model to estimate the hazard functions (H(t)), with the hazard ratio (HR) and their respective intervals of confidence (95%CI), according to age group. The analysis was performed using Stata software version 16.0. Results: From 2000 to 2016, 3,671 new cases and 892 deaths from prostate cancer were recorded in Cuiabá and Várzea Grande. The average of rates in the period (100,000 inhabitants) was 87.96 for incidence and 20.22 for mortality. There was a downward trend in the incidence rate for all ages from 2006 to 2016 (APC=-3.2%) and for men aged 80 years and over from 2000 to 2016 (APC=-3.0%), as well as increasing trend in the mortality rate in men aged 60–69 years from 2000 to 2009 (APC=3.2%). The probability of specific survival at five years was 79.6% (95%CI: 77.2; 81.9) and decreased with increasing age (HR=2.43; 95%CI: 1.5; 3.9 for those aged 70 to 79 years and HR=7.20; 95%CI: 4.5;11.5 for those aged 80 years and over). Final considerations: The present study advanced in describing the indicators of incidence, mortality and survival of prostate cancer in the municipalities of Cuiabá and Várzea Grande. A reduction in the incidence rate and stability of mortality was observed, as well as a higher specific survival probability than in other Brazilian studies, although lower than that observed in developed countries. From the analyzes carried out, it is possible to conclude that, despite advances in diagnosis and treatment, prostate cancer requires confrontation.
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spelling Câncer de próstata : incidência, mortalidade e sobrevida de residentes em Cuiabá e Várzea GrandeCâncer de próstataIncidênciaMortalidadeSobrevidaCNPQ::CIENCIAS DA SAUDE::SAUDE COLETIVAProstate cancerIncidenceMortalitySurvivalProstate cancer was the second most frequent and the fifth leading cause of cancer death among men in 2020 worldwide. It is important to know the epidemiological picture of cancer so that we can advance in prevention and control. Objective: To analyze the incidence, mortality and survival from prostate cancer in men living in Cuiabá and Várzea Grande, from 2000 to 2016. Methods: Study carried out in the cities of Cuiabá and Várzea Grande that analyzed the incidence, mortality and survival of prostate cancer. Data were obtained through the Population-Based Cancer Registry (RCBP) and Mortality Information System (SIM), from an extension project developed at the Instituto de Saúde Coletiva of the Federal University of Mato Grosso and entitled “Cancer and Its Diseases”. Associated Factors: Analysis of Population-Based and Hospital Registry of Mato Grosso”. Incidence and mortality rates for prostate cancer were calculated by year (2000 to 2016) and by age group, dividing the number of new cases by the population and multiplying by 100,000 inhabitants. Joinpoint method, calculating the annual percentage change (APC) and Average Annual Percentage Change (AAPC) using the Jointpoint Regression Program software. To calculate survival, a probabilistic relationship was performed between the cases registered in the RCBP between 2008 and 2012 and in the SIM between 2008 and 2017, using the RecLink III software. The Kaplan-Meier estimator method was used to analyze the survival curves and the semiparametric Cox proportional hazards model to estimate the hazard functions (H(t)), with the hazard ratio (HR) and their respective intervals of confidence (95%CI), according to age group. The analysis was performed using Stata software version 16.0. Results: From 2000 to 2016, 3,671 new cases and 892 deaths from prostate cancer were recorded in Cuiabá and Várzea Grande. The average of rates in the period (100,000 inhabitants) was 87.96 for incidence and 20.22 for mortality. There was a downward trend in the incidence rate for all ages from 2006 to 2016 (APC=-3.2%) and for men aged 80 years and over from 2000 to 2016 (APC=-3.0%), as well as increasing trend in the mortality rate in men aged 60–69 years from 2000 to 2009 (APC=3.2%). The probability of specific survival at five years was 79.6% (95%CI: 77.2; 81.9) and decreased with increasing age (HR=2.43; 95%CI: 1.5; 3.9 for those aged 70 to 79 years and HR=7.20; 95%CI: 4.5;11.5 for those aged 80 years and over). Final considerations: The present study advanced in describing the indicators of incidence, mortality and survival of prostate cancer in the municipalities of Cuiabá and Várzea Grande. A reduction in the incidence rate and stability of mortality was observed, as well as a higher specific survival probability than in other Brazilian studies, although lower than that observed in developed countries. From the analyzes carried out, it is possible to conclude that, despite advances in diagnosis and treatment, prostate cancer requires confrontation.CAPESO câncer de próstata foi o segundo mais frequente e a quinta principal causa de morte por câncer entre os homens em 2020 no mundo. Faz-se importante conhecer o quadro epidemiológico do câncer para que se possa avançar na prevenção e controle. Objetivo: Analisar a incidência, mortalidade e sobrevida por câncer de próstata em homens residentes em Cuiabá e Várzea Grande, no período de 2000 a 2016. Métodos: Estudo realizado nas cidades de Cuiabá e Várzea Grande que analisou a incidência, mortalidade e sobrevida de câncer de próstata. Os dados foram obtidos por meio do Registro de Câncer de Base Populacional (RCBP) e Sistema de Informação de Mortalidade (SIM), provenientes de um projeto de extensão desenvolvido no Instituto de Saúde Coletiva da Universidade Federal de Mato Grosso e intitulado “Câncer e Seus Fatores Associados: Análises de Registro Base Populacional e Hospitalar De Mato Grosso”. As taxas de incidência e mortalidade por câncer de próstata foram calculadas por ano (2000 a 2016) e por faixa etária, dividindo-se o número de casos novos pela população e multiplicando-se por 100.000 habitantes A análise da tendência das taxas foi feita pelo método Joinpoint, calculadas a variação percentual anual (APC) e Variação Percentual Média Anual (AAPC) com a utilização do software Jointpoint Regression Program. Para o cálculo de sobrevida, foi realizado relacionamento probabilístico entre os casos registrados no RCBP entre 2008 a 2012 e no SIM entre 2008 a 2017, pelo software RecLink III. Foi utilizado o método de estimador Kaplan-Meier na análise das curvas de sobrevivência e o modelo semiparamétrico de riscos proporcionais de Cox para estimar as funções de risco (H(t)), com apresentação do hazard ratio (HR) e seus respectivos intervalos de confiança (IC95%), segundo faixa etária. A análise foi realizada no software Stata versão 16.0. Resultados: De 2000 a 2016, foram registrados 3.671 casos novos e 892 óbitos por câncer de próstata em Cuiabá e Várzea Grande. A média das taxas no período (100.000 habitantes) foi de 87,96 para incidência e 20,22 para mortalidade. Verificou-se tendência decrescente da taxa de incidência para todas as idades de 2006 a 2016 (APC=-3,2%) e para homens com 80 anos ou mais de 2000 a 2016 (APC=-3,0%), bem como tendência crescente da taxa de mortalidade nos homens de 60–69 anos de 2000 a 2009 (APC=3,2%). A probabilidade de sobrevida específica em cinco anos foi de 79,6% (IC95%: 77,2; 81,9) e diminuiu com o aumento da faixa etária (HR=2,43; IC95%: 1,5; 3,9 para aqueles de 70 a 79 anos e HR= 7,20; IC95%: 4,5;11,5 para aqueles de 80 anos ou mais). Considerações finais: O presente estudo avançou ao descrever os indicadores de incidência, mortalidade e sobrevida de câncer de próstata nos municípios de Cuiabá e Várzea Grande. Foi observado redução na taxa de incidência e estabilidade da mortalidade, e uma probabilidade de sobrevida específica maior do que em outros estudos brasileiros, entretanto menor do que observado em países desenvolvidos. A partir das análises realizadas é possível concluir que, apesar dos avanços no diagnóstico e tratamento, o câncer de próstata requer enfrentamento.Universidade Federal de Mato GrossoBrasilInstituto de Saúde Coletiva (ISC)UFMT CUC - CuiabáPrograma de Pós-Graduação em Saúde ColetivaAndrade, Amanda Cristina de SouzaMelanda, Francine Nesellohttp://lattes.cnpq.br/1832895922286506http://lattes.cnpq.br/2405137871559865Andrade, Amanda Cristina de Souza076.194.226-25Neuciani Ferreira da Silva Sousahttp://lattes.cnpq.br/2405137871559865Sousa, Neuciani Ferreira da Silva003.175.551-89http://lattes.cnpq.br/9222165448119998076.194.226-25058.216.809-05Loch, Mathias Roberto007.043.829-38http://lattes.cnpq.br/4936998732163718Evangelista, Flávio de Macêdo2024-09-09T14:03:14Z2022-08-252024-09-09T14:03:14Z2022-07-25info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisEVANGELISTA, Flávio de Macêdo. Câncer de próstata: incidência, mortalidade e sobrevida de residentes em Cuiabá e Várzea Grande. 2022. 80 f. Dissertação (Mestrado em Saúde Coletiva) - Universidade Federal de Mato Grosso, Instituto de Saúde Coletiva, Cuiabá, 2022.http://ri.ufmt.br/handle/1/5894porinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMTinstname:Universidade Federal de Mato Grosso (UFMT)instacron:UFMT2024-09-16T07:01:14Zoai:localhost:1/5894Repositório InstitucionalPUBhttp://ri.ufmt.br/oai/requestjordanbiblio@gmail.comopendoar:2024-09-16T07:01:14Repositório Institucional da UFMT - Universidade Federal de Mato Grosso (UFMT)false
dc.title.none.fl_str_mv Câncer de próstata : incidência, mortalidade e sobrevida de residentes em Cuiabá e Várzea Grande
title Câncer de próstata : incidência, mortalidade e sobrevida de residentes em Cuiabá e Várzea Grande
spellingShingle Câncer de próstata : incidência, mortalidade e sobrevida de residentes em Cuiabá e Várzea Grande
Evangelista, Flávio de Macêdo
Câncer de próstata
Incidência
Mortalidade
Sobrevida
CNPQ::CIENCIAS DA SAUDE::SAUDE COLETIVA
Prostate cancer
Incidence
Mortality
Survival
title_short Câncer de próstata : incidência, mortalidade e sobrevida de residentes em Cuiabá e Várzea Grande
title_full Câncer de próstata : incidência, mortalidade e sobrevida de residentes em Cuiabá e Várzea Grande
title_fullStr Câncer de próstata : incidência, mortalidade e sobrevida de residentes em Cuiabá e Várzea Grande
title_full_unstemmed Câncer de próstata : incidência, mortalidade e sobrevida de residentes em Cuiabá e Várzea Grande
title_sort Câncer de próstata : incidência, mortalidade e sobrevida de residentes em Cuiabá e Várzea Grande
author Evangelista, Flávio de Macêdo
author_facet Evangelista, Flávio de Macêdo
author_role author
dc.contributor.none.fl_str_mv Andrade, Amanda Cristina de Souza
Melanda, Francine Nesello
http://lattes.cnpq.br/1832895922286506
http://lattes.cnpq.br/2405137871559865
Andrade, Amanda Cristina de Souza
076.194.226-25Neuciani Ferreira da Silva Sousa
http://lattes.cnpq.br/2405137871559865
Sousa, Neuciani Ferreira da Silva
003.175.551-89
http://lattes.cnpq.br/9222165448119998
076.194.226-25
058.216.809-05
Loch, Mathias Roberto
007.043.829-38
http://lattes.cnpq.br/4936998732163718
dc.contributor.author.fl_str_mv Evangelista, Flávio de Macêdo
dc.subject.por.fl_str_mv Câncer de próstata
Incidência
Mortalidade
Sobrevida
CNPQ::CIENCIAS DA SAUDE::SAUDE COLETIVA
Prostate cancer
Incidence
Mortality
Survival
topic Câncer de próstata
Incidência
Mortalidade
Sobrevida
CNPQ::CIENCIAS DA SAUDE::SAUDE COLETIVA
Prostate cancer
Incidence
Mortality
Survival
description Prostate cancer was the second most frequent and the fifth leading cause of cancer death among men in 2020 worldwide. It is important to know the epidemiological picture of cancer so that we can advance in prevention and control. Objective: To analyze the incidence, mortality and survival from prostate cancer in men living in Cuiabá and Várzea Grande, from 2000 to 2016. Methods: Study carried out in the cities of Cuiabá and Várzea Grande that analyzed the incidence, mortality and survival of prostate cancer. Data were obtained through the Population-Based Cancer Registry (RCBP) and Mortality Information System (SIM), from an extension project developed at the Instituto de Saúde Coletiva of the Federal University of Mato Grosso and entitled “Cancer and Its Diseases”. Associated Factors: Analysis of Population-Based and Hospital Registry of Mato Grosso”. Incidence and mortality rates for prostate cancer were calculated by year (2000 to 2016) and by age group, dividing the number of new cases by the population and multiplying by 100,000 inhabitants. Joinpoint method, calculating the annual percentage change (APC) and Average Annual Percentage Change (AAPC) using the Jointpoint Regression Program software. To calculate survival, a probabilistic relationship was performed between the cases registered in the RCBP between 2008 and 2012 and in the SIM between 2008 and 2017, using the RecLink III software. The Kaplan-Meier estimator method was used to analyze the survival curves and the semiparametric Cox proportional hazards model to estimate the hazard functions (H(t)), with the hazard ratio (HR) and their respective intervals of confidence (95%CI), according to age group. The analysis was performed using Stata software version 16.0. Results: From 2000 to 2016, 3,671 new cases and 892 deaths from prostate cancer were recorded in Cuiabá and Várzea Grande. The average of rates in the period (100,000 inhabitants) was 87.96 for incidence and 20.22 for mortality. There was a downward trend in the incidence rate for all ages from 2006 to 2016 (APC=-3.2%) and for men aged 80 years and over from 2000 to 2016 (APC=-3.0%), as well as increasing trend in the mortality rate in men aged 60–69 years from 2000 to 2009 (APC=3.2%). The probability of specific survival at five years was 79.6% (95%CI: 77.2; 81.9) and decreased with increasing age (HR=2.43; 95%CI: 1.5; 3.9 for those aged 70 to 79 years and HR=7.20; 95%CI: 4.5;11.5 for those aged 80 years and over). Final considerations: The present study advanced in describing the indicators of incidence, mortality and survival of prostate cancer in the municipalities of Cuiabá and Várzea Grande. A reduction in the incidence rate and stability of mortality was observed, as well as a higher specific survival probability than in other Brazilian studies, although lower than that observed in developed countries. From the analyzes carried out, it is possible to conclude that, despite advances in diagnosis and treatment, prostate cancer requires confrontation.
publishDate 2022
dc.date.none.fl_str_mv 2022-08-25
2022-07-25
2024-09-09T14:03:14Z
2024-09-09T14:03:14Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.uri.fl_str_mv EVANGELISTA, Flávio de Macêdo. Câncer de próstata: incidência, mortalidade e sobrevida de residentes em Cuiabá e Várzea Grande. 2022. 80 f. Dissertação (Mestrado em Saúde Coletiva) - Universidade Federal de Mato Grosso, Instituto de Saúde Coletiva, Cuiabá, 2022.
http://ri.ufmt.br/handle/1/5894
identifier_str_mv EVANGELISTA, Flávio de Macêdo. Câncer de próstata: incidência, mortalidade e sobrevida de residentes em Cuiabá e Várzea Grande. 2022. 80 f. Dissertação (Mestrado em Saúde Coletiva) - Universidade Federal de Mato Grosso, Instituto de Saúde Coletiva, Cuiabá, 2022.
url http://ri.ufmt.br/handle/1/5894
dc.language.iso.fl_str_mv por
language por
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Universidade Federal de Mato Grosso
Brasil
Instituto de Saúde Coletiva (ISC)
UFMT CUC - Cuiabá
Programa de Pós-Graduação em Saúde Coletiva
publisher.none.fl_str_mv Universidade Federal de Mato Grosso
Brasil
Instituto de Saúde Coletiva (ISC)
UFMT CUC - Cuiabá
Programa de Pós-Graduação em Saúde Coletiva
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFMT
instname:Universidade Federal de Mato Grosso (UFMT)
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instname_str Universidade Federal de Mato Grosso (UFMT)
instacron_str UFMT
institution UFMT
reponame_str Repositório Institucional da UFMT
collection Repositório Institucional da UFMT
repository.name.fl_str_mv Repositório Institucional da UFMT - Universidade Federal de Mato Grosso (UFMT)
repository.mail.fl_str_mv jordanbiblio@gmail.com
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