Avaliação clínica da aplicação local de gel de lorexidina com microbrush no tratamento de bolsas periodontais residuais

Detalhes bibliográficos
Ano de defesa: 2015
Autor(a) principal: Gonçalves, Elonice Melo de Sousa lattes
Orientador(a): Lopes, Beatriz Maria Valério lattes
Banca de defesa: Não Informado pela instituição
Tipo de documento: Tese
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade do Sagrado Coração
Programa de Pós-Graduação: Biologia Oral
Departamento: Ciências da Saúde e Biológicas
País: Brasil
Palavras-chave em Português:
PCR
Palavras-chave em Inglês:
PRC
Área do conhecimento CNPq:
Link de acesso: http://tede2.usc.br:8080/jspui/handle/tede/282
Resumo: Topical application of antibiotics and antibacterials in the treatment of nonresponders located sites can overcome the shortcomings of scaling and root planning (SRP) therapy. The purpose of this split-mouth study, was to evaluate the clinical and microbiological effects, in short time, the chlorhexidine gel 0.2% in control of subgingival plaque in 20 patients with chronic periodontitis previously treated with SRP. All 4 patients had residual periodontal pockets with probing depth (PD) ≥ 5 mm and bleeding on probing and were randomly divided into groups: negative control (C), positive control (SRP), SRP + chlorhexidine (SRPC) and chlorhexidine test (CLX). The visible plaque index (PI), gingival bleeding index (GI), probing depth (PD), bleeding on probing (BOP), gingival recession (GR) and clinical attachment level (CAL) clinical parameters were evaluated by a calibrated and trained researcher who performed the periodontal monitoring at baseline, 30, 90 and 180 days after treatments. The presence of periodontal pathogens Aggregatibacter actinomycetemcomitans (Aa), Porphyromonas gingivalis (Pg), Prevotella intermedia (Pi) and Tannerella forsythia (Tf) was assessed by means of PRC. Data were statistically analyzed by softawe Boestat 5.0. The level of significance was 5%. Six months after treatment, PI and GI reduced for all groups (p <0.05); SRP, SRPC and CLX groups showed a reduction in BOP and also significantly reduced the BOP when compared to C (p <0.05). The PD was reduced to SRP, SRPC and CLX (p <0.05) groups; CAL increased for SRPC and SRP (p <0.05) and GR increased to SRP C and CLX (p <0.05). The SRPC and CLX groups showed significant reduction in the percentage of sites with presence of some bacteria (p <0.05). The RARC group showed the lowest prevalence of bacteria compared differences between groups. The use of chlorhexidine gel with microbrush, with or without the SRP, as an alternative for the treatment of residual periodontal pockets promotes microbiological benefits without providing significant clinical changes.
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spelling Lopes, Beatriz Maria Valério14963720850http://lattes.cnpq.br/694427162796804347928522349http://lattes.cnpq.br/8164848932834538Gonçalves, Elonice Melo de Sousa2016-01-28T12:58:02Z2015-02-23GONCALVES, Elonice Melo de Sousa. Avaliação clínica da aplicação local de gel de lorexidina com microbrush no tratamento de bolsas periodontais residuais. 2015. 58 f. Tese (Doutorado em Biologia Oral) - Universidade do Sagrado Coração, Bauru, 2015.http://tede2.usc.br:8080/jspui/handle/tede/282Topical application of antibiotics and antibacterials in the treatment of nonresponders located sites can overcome the shortcomings of scaling and root planning (SRP) therapy. The purpose of this split-mouth study, was to evaluate the clinical and microbiological effects, in short time, the chlorhexidine gel 0.2% in control of subgingival plaque in 20 patients with chronic periodontitis previously treated with SRP. All 4 patients had residual periodontal pockets with probing depth (PD) ≥ 5 mm and bleeding on probing and were randomly divided into groups: negative control (C), positive control (SRP), SRP + chlorhexidine (SRPC) and chlorhexidine test (CLX). The visible plaque index (PI), gingival bleeding index (GI), probing depth (PD), bleeding on probing (BOP), gingival recession (GR) and clinical attachment level (CAL) clinical parameters were evaluated by a calibrated and trained researcher who performed the periodontal monitoring at baseline, 30, 90 and 180 days after treatments. The presence of periodontal pathogens Aggregatibacter actinomycetemcomitans (Aa), Porphyromonas gingivalis (Pg), Prevotella intermedia (Pi) and Tannerella forsythia (Tf) was assessed by means of PRC. Data were statistically analyzed by softawe Boestat 5.0. The level of significance was 5%. Six months after treatment, PI and GI reduced for all groups (p <0.05); SRP, SRPC and CLX groups showed a reduction in BOP and also significantly reduced the BOP when compared to C (p <0.05). The PD was reduced to SRP, SRPC and CLX (p <0.05) groups; CAL increased for SRPC and SRP (p <0.05) and GR increased to SRP C and CLX (p <0.05). The SRPC and CLX groups showed significant reduction in the percentage of sites with presence of some bacteria (p <0.05). The RARC group showed the lowest prevalence of bacteria compared differences between groups. The use of chlorhexidine gel with microbrush, with or without the SRP, as an alternative for the treatment of residual periodontal pockets promotes microbiological benefits without providing significant clinical changes.A aplicação tópica de antibióticos e antibacterianos no tratamento localizado de sítios não respondentes pode superar as deficiências da terapia de raspagem e alisamento radicular (RAR). O objetivo do presente estudo, de boca dividida, foi avaliar clínica e microbiologicamente o efeito, em curto período, do gel de clorexidina 0,2% no controle de placa subgengival em 20 pacientes portadores de periodontite crônica previamente tratados com RAR. Todos os pacientes apresentavam 4 bolsas periodontais residuais com profundidade de sondagem (PS) ≥ 5mm e sangramento à sondagem e foram divididos aleatoriamente em grupos: controle negativo (C), controle positivo (RAR), RAR+clorexidina (RARC) e clorexidina teste (CLX). Os parâmetros clínicos índice de placa visível (IP), índice de sangramento gengival (IG), profundidade de sondagem (PS), sangramento à sondagem (SS), recessão gengival (RG) e nível de inserção clínica (NI) foram avaliados por um pesquisador calibrado e treinado que realizou o acompanhamento periodontal no baseline, 30, 90 e 180 dias após os tratamentos. A presença dos periodontopatógenos Aggregatibacter actinomycetemcomitans (Aa), Porphyromonas gingivalis (Pg), Prevotella intermedia (Pi) e Tannerella forsythia (Tf) foi avaliada pela técnica de PCR. Os dados foram tabulados e analisados estatisticamente pelo software Bioestat 5.0. O nível de significância considerado foi de 5%. Cento e oitenta dias após os tratamentos, IP e IG reduziram para todos os grupos (p<0,05); os grupos RAR, RARC e CLX apresentaram redução no SS e ainda, reduziram significantemente o SS quando comparados ao C (p<0,05). A PS reduziu para os grupos RAR, RARC e CLX (p<0,05); o NI aumentou para RAR e RARC (p<0,05) e RG aumentou para RARC e CLX (p<0,05). Os grupos RARC e CLX demonstraram redução significante na porcentagem de sítios com presença de alguma bactéria (p<0,05). O grupo RARC foi o que apresentou menor prevalência de bactérias presentes quando comparadas as diferenças entre os grupos. O uso de gel clorexidina com microbrush, associado ou não a raspagem, como alternativa para o tratamento de bolsas periodontais residuais promove benefícios microbiológicos sem contudo apresentar alterações clínicas significativas.Submitted by Valquiria Tavares (valquiria.tavares@usc.br) on 2016-01-28T12:58:02Z No. of bitstreams: 1 tese_elonice_goncalves.pdf: 1614572 bytes, checksum: 38af94d5d589741f892ce6667a0ec6ca (MD5)Made available in DSpace on 2016-01-28T12:58:02Z (GMT). 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dc.title.eng.fl_str_mv Avaliação clínica da aplicação local de gel de lorexidina com microbrush no tratamento de bolsas periodontais residuais
dc.title.alternative.eng.fl_str_mv Clinical evaluation of local application of chlorhexidine gel with microbrush in the treatment of periodontal pockets waste
title Avaliação clínica da aplicação local de gel de lorexidina com microbrush no tratamento de bolsas periodontais residuais
spellingShingle Avaliação clínica da aplicação local de gel de lorexidina com microbrush no tratamento de bolsas periodontais residuais
Gonçalves, Elonice Melo de Sousa
Periodontite
Clorexidina
Microbrush
PCR
Análise Microbiológica
Periodontitis
Chlorhexidine
Microbrush
PRC
Microbiological analysis
CIENCIAS DA SAUDE::ODONTOLOGIA
title_short Avaliação clínica da aplicação local de gel de lorexidina com microbrush no tratamento de bolsas periodontais residuais
title_full Avaliação clínica da aplicação local de gel de lorexidina com microbrush no tratamento de bolsas periodontais residuais
title_fullStr Avaliação clínica da aplicação local de gel de lorexidina com microbrush no tratamento de bolsas periodontais residuais
title_full_unstemmed Avaliação clínica da aplicação local de gel de lorexidina com microbrush no tratamento de bolsas periodontais residuais
title_sort Avaliação clínica da aplicação local de gel de lorexidina com microbrush no tratamento de bolsas periodontais residuais
author Gonçalves, Elonice Melo de Sousa
author_facet Gonçalves, Elonice Melo de Sousa
author_role author
dc.contributor.advisor1.fl_str_mv Lopes, Beatriz Maria Valério
dc.contributor.advisor1ID.fl_str_mv 14963720850
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/6944271627968043
dc.contributor.authorID.fl_str_mv 47928522349
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/8164848932834538
dc.contributor.author.fl_str_mv Gonçalves, Elonice Melo de Sousa
contributor_str_mv Lopes, Beatriz Maria Valério
dc.subject.por.fl_str_mv Periodontite
Clorexidina
Microbrush
PCR
Análise Microbiológica
topic Periodontite
Clorexidina
Microbrush
PCR
Análise Microbiológica
Periodontitis
Chlorhexidine
Microbrush
PRC
Microbiological analysis
CIENCIAS DA SAUDE::ODONTOLOGIA
dc.subject.eng.fl_str_mv Periodontitis
Chlorhexidine
Microbrush
PRC
Microbiological analysis
dc.subject.cnpq.fl_str_mv CIENCIAS DA SAUDE::ODONTOLOGIA
description Topical application of antibiotics and antibacterials in the treatment of nonresponders located sites can overcome the shortcomings of scaling and root planning (SRP) therapy. The purpose of this split-mouth study, was to evaluate the clinical and microbiological effects, in short time, the chlorhexidine gel 0.2% in control of subgingival plaque in 20 patients with chronic periodontitis previously treated with SRP. All 4 patients had residual periodontal pockets with probing depth (PD) ≥ 5 mm and bleeding on probing and were randomly divided into groups: negative control (C), positive control (SRP), SRP + chlorhexidine (SRPC) and chlorhexidine test (CLX). The visible plaque index (PI), gingival bleeding index (GI), probing depth (PD), bleeding on probing (BOP), gingival recession (GR) and clinical attachment level (CAL) clinical parameters were evaluated by a calibrated and trained researcher who performed the periodontal monitoring at baseline, 30, 90 and 180 days after treatments. The presence of periodontal pathogens Aggregatibacter actinomycetemcomitans (Aa), Porphyromonas gingivalis (Pg), Prevotella intermedia (Pi) and Tannerella forsythia (Tf) was assessed by means of PRC. Data were statistically analyzed by softawe Boestat 5.0. The level of significance was 5%. Six months after treatment, PI and GI reduced for all groups (p <0.05); SRP, SRPC and CLX groups showed a reduction in BOP and also significantly reduced the BOP when compared to C (p <0.05). The PD was reduced to SRP, SRPC and CLX (p <0.05) groups; CAL increased for SRPC and SRP (p <0.05) and GR increased to SRP C and CLX (p <0.05). The SRPC and CLX groups showed significant reduction in the percentage of sites with presence of some bacteria (p <0.05). The RARC group showed the lowest prevalence of bacteria compared differences between groups. The use of chlorhexidine gel with microbrush, with or without the SRP, as an alternative for the treatment of residual periodontal pockets promotes microbiological benefits without providing significant clinical changes.
publishDate 2015
dc.date.issued.fl_str_mv 2015-02-23
dc.date.accessioned.fl_str_mv 2016-01-28T12:58:02Z
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dc.identifier.citation.fl_str_mv GONCALVES, Elonice Melo de Sousa. Avaliação clínica da aplicação local de gel de lorexidina com microbrush no tratamento de bolsas periodontais residuais. 2015. 58 f. Tese (Doutorado em Biologia Oral) - Universidade do Sagrado Coração, Bauru, 2015.
dc.identifier.uri.fl_str_mv http://tede2.usc.br:8080/jspui/handle/tede/282
identifier_str_mv GONCALVES, Elonice Melo de Sousa. Avaliação clínica da aplicação local de gel de lorexidina com microbrush no tratamento de bolsas periodontais residuais. 2015. 58 f. Tese (Doutorado em Biologia Oral) - Universidade do Sagrado Coração, Bauru, 2015.
url http://tede2.usc.br:8080/jspui/handle/tede/282
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dc.publisher.department.fl_str_mv Ciências da Saúde e Biológicas
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