Avaliação clínica da aplicação local de gel de lorexidina com microbrush no tratamento de bolsas periodontais residuais
Ano de defesa: | 2015 |
---|---|
Autor(a) principal: | |
Orientador(a): | |
Banca de defesa: | |
Tipo de documento: | Tese |
Tipo de acesso: | Acesso aberto |
Idioma: | por |
Instituição de defesa: |
Universidade do Sagrado Coração
|
Programa de Pós-Graduação: |
Biologia Oral
|
Departamento: |
Ciências da Saúde e Biológicas
|
País: |
Brasil
|
Palavras-chave em Português: | |
Palavras-chave em Inglês: | |
Área do conhecimento CNPq: | |
Link de acesso: | http://tede2.usc.br:8080/jspui/handle/tede/282 |
Resumo: | Topical application of antibiotics and antibacterials in the treatment of nonresponders located sites can overcome the shortcomings of scaling and root planning (SRP) therapy. The purpose of this split-mouth study, was to evaluate the clinical and microbiological effects, in short time, the chlorhexidine gel 0.2% in control of subgingival plaque in 20 patients with chronic periodontitis previously treated with SRP. All 4 patients had residual periodontal pockets with probing depth (PD) ≥ 5 mm and bleeding on probing and were randomly divided into groups: negative control (C), positive control (SRP), SRP + chlorhexidine (SRPC) and chlorhexidine test (CLX). The visible plaque index (PI), gingival bleeding index (GI), probing depth (PD), bleeding on probing (BOP), gingival recession (GR) and clinical attachment level (CAL) clinical parameters were evaluated by a calibrated and trained researcher who performed the periodontal monitoring at baseline, 30, 90 and 180 days after treatments. The presence of periodontal pathogens Aggregatibacter actinomycetemcomitans (Aa), Porphyromonas gingivalis (Pg), Prevotella intermedia (Pi) and Tannerella forsythia (Tf) was assessed by means of PRC. Data were statistically analyzed by softawe Boestat 5.0. The level of significance was 5%. Six months after treatment, PI and GI reduced for all groups (p <0.05); SRP, SRPC and CLX groups showed a reduction in BOP and also significantly reduced the BOP when compared to C (p <0.05). The PD was reduced to SRP, SRPC and CLX (p <0.05) groups; CAL increased for SRPC and SRP (p <0.05) and GR increased to SRP C and CLX (p <0.05). The SRPC and CLX groups showed significant reduction in the percentage of sites with presence of some bacteria (p <0.05). The RARC group showed the lowest prevalence of bacteria compared differences between groups. The use of chlorhexidine gel with microbrush, with or without the SRP, as an alternative for the treatment of residual periodontal pockets promotes microbiological benefits without providing significant clinical changes. |
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Lopes, Beatriz Maria Valério14963720850http://lattes.cnpq.br/694427162796804347928522349http://lattes.cnpq.br/8164848932834538Gonçalves, Elonice Melo de Sousa2016-01-28T12:58:02Z2015-02-23GONCALVES, Elonice Melo de Sousa. Avaliação clínica da aplicação local de gel de lorexidina com microbrush no tratamento de bolsas periodontais residuais. 2015. 58 f. Tese (Doutorado em Biologia Oral) - Universidade do Sagrado Coração, Bauru, 2015.http://tede2.usc.br:8080/jspui/handle/tede/282Topical application of antibiotics and antibacterials in the treatment of nonresponders located sites can overcome the shortcomings of scaling and root planning (SRP) therapy. The purpose of this split-mouth study, was to evaluate the clinical and microbiological effects, in short time, the chlorhexidine gel 0.2% in control of subgingival plaque in 20 patients with chronic periodontitis previously treated with SRP. All 4 patients had residual periodontal pockets with probing depth (PD) ≥ 5 mm and bleeding on probing and were randomly divided into groups: negative control (C), positive control (SRP), SRP + chlorhexidine (SRPC) and chlorhexidine test (CLX). The visible plaque index (PI), gingival bleeding index (GI), probing depth (PD), bleeding on probing (BOP), gingival recession (GR) and clinical attachment level (CAL) clinical parameters were evaluated by a calibrated and trained researcher who performed the periodontal monitoring at baseline, 30, 90 and 180 days after treatments. The presence of periodontal pathogens Aggregatibacter actinomycetemcomitans (Aa), Porphyromonas gingivalis (Pg), Prevotella intermedia (Pi) and Tannerella forsythia (Tf) was assessed by means of PRC. Data were statistically analyzed by softawe Boestat 5.0. The level of significance was 5%. Six months after treatment, PI and GI reduced for all groups (p <0.05); SRP, SRPC and CLX groups showed a reduction in BOP and also significantly reduced the BOP when compared to C (p <0.05). The PD was reduced to SRP, SRPC and CLX (p <0.05) groups; CAL increased for SRPC and SRP (p <0.05) and GR increased to SRP C and CLX (p <0.05). The SRPC and CLX groups showed significant reduction in the percentage of sites with presence of some bacteria (p <0.05). The RARC group showed the lowest prevalence of bacteria compared differences between groups. The use of chlorhexidine gel with microbrush, with or without the SRP, as an alternative for the treatment of residual periodontal pockets promotes microbiological benefits without providing significant clinical changes.A aplicação tópica de antibióticos e antibacterianos no tratamento localizado de sítios não respondentes pode superar as deficiências da terapia de raspagem e alisamento radicular (RAR). O objetivo do presente estudo, de boca dividida, foi avaliar clínica e microbiologicamente o efeito, em curto período, do gel de clorexidina 0,2% no controle de placa subgengival em 20 pacientes portadores de periodontite crônica previamente tratados com RAR. Todos os pacientes apresentavam 4 bolsas periodontais residuais com profundidade de sondagem (PS) ≥ 5mm e sangramento à sondagem e foram divididos aleatoriamente em grupos: controle negativo (C), controle positivo (RAR), RAR+clorexidina (RARC) e clorexidina teste (CLX). Os parâmetros clínicos índice de placa visível (IP), índice de sangramento gengival (IG), profundidade de sondagem (PS), sangramento à sondagem (SS), recessão gengival (RG) e nível de inserção clínica (NI) foram avaliados por um pesquisador calibrado e treinado que realizou o acompanhamento periodontal no baseline, 30, 90 e 180 dias após os tratamentos. A presença dos periodontopatógenos Aggregatibacter actinomycetemcomitans (Aa), Porphyromonas gingivalis (Pg), Prevotella intermedia (Pi) e Tannerella forsythia (Tf) foi avaliada pela técnica de PCR. Os dados foram tabulados e analisados estatisticamente pelo software Bioestat 5.0. O nível de significância considerado foi de 5%. Cento e oitenta dias após os tratamentos, IP e IG reduziram para todos os grupos (p<0,05); os grupos RAR, RARC e CLX apresentaram redução no SS e ainda, reduziram significantemente o SS quando comparados ao C (p<0,05). A PS reduziu para os grupos RAR, RARC e CLX (p<0,05); o NI aumentou para RAR e RARC (p<0,05) e RG aumentou para RARC e CLX (p<0,05). Os grupos RARC e CLX demonstraram redução significante na porcentagem de sítios com presença de alguma bactéria (p<0,05). O grupo RARC foi o que apresentou menor prevalência de bactérias presentes quando comparadas as diferenças entre os grupos. O uso de gel clorexidina com microbrush, associado ou não a raspagem, como alternativa para o tratamento de bolsas periodontais residuais promove benefícios microbiológicos sem contudo apresentar alterações clínicas significativas.Submitted by Valquiria Tavares (valquiria.tavares@usc.br) on 2016-01-28T12:58:02Z No. of bitstreams: 1 tese_elonice_goncalves.pdf: 1614572 bytes, checksum: 38af94d5d589741f892ce6667a0ec6ca (MD5)Made available in DSpace on 2016-01-28T12:58:02Z (GMT). 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dc.title.eng.fl_str_mv |
Avaliação clínica da aplicação local de gel de lorexidina com microbrush no tratamento de bolsas periodontais residuais |
dc.title.alternative.eng.fl_str_mv |
Clinical evaluation of local application of chlorhexidine gel with microbrush in the treatment of periodontal pockets waste |
title |
Avaliação clínica da aplicação local de gel de lorexidina com microbrush no tratamento de bolsas periodontais residuais |
spellingShingle |
Avaliação clínica da aplicação local de gel de lorexidina com microbrush no tratamento de bolsas periodontais residuais Gonçalves, Elonice Melo de Sousa Periodontite Clorexidina Microbrush PCR Análise Microbiológica Periodontitis Chlorhexidine Microbrush PRC Microbiological analysis CIENCIAS DA SAUDE::ODONTOLOGIA |
title_short |
Avaliação clínica da aplicação local de gel de lorexidina com microbrush no tratamento de bolsas periodontais residuais |
title_full |
Avaliação clínica da aplicação local de gel de lorexidina com microbrush no tratamento de bolsas periodontais residuais |
title_fullStr |
Avaliação clínica da aplicação local de gel de lorexidina com microbrush no tratamento de bolsas periodontais residuais |
title_full_unstemmed |
Avaliação clínica da aplicação local de gel de lorexidina com microbrush no tratamento de bolsas periodontais residuais |
title_sort |
Avaliação clínica da aplicação local de gel de lorexidina com microbrush no tratamento de bolsas periodontais residuais |
author |
Gonçalves, Elonice Melo de Sousa |
author_facet |
Gonçalves, Elonice Melo de Sousa |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Lopes, Beatriz Maria Valério |
dc.contributor.advisor1ID.fl_str_mv |
14963720850 |
dc.contributor.advisor1Lattes.fl_str_mv |
http://lattes.cnpq.br/6944271627968043 |
dc.contributor.authorID.fl_str_mv |
47928522349 |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/8164848932834538 |
dc.contributor.author.fl_str_mv |
Gonçalves, Elonice Melo de Sousa |
contributor_str_mv |
Lopes, Beatriz Maria Valério |
dc.subject.por.fl_str_mv |
Periodontite Clorexidina Microbrush PCR Análise Microbiológica |
topic |
Periodontite Clorexidina Microbrush PCR Análise Microbiológica Periodontitis Chlorhexidine Microbrush PRC Microbiological analysis CIENCIAS DA SAUDE::ODONTOLOGIA |
dc.subject.eng.fl_str_mv |
Periodontitis Chlorhexidine Microbrush PRC Microbiological analysis |
dc.subject.cnpq.fl_str_mv |
CIENCIAS DA SAUDE::ODONTOLOGIA |
description |
Topical application of antibiotics and antibacterials in the treatment of nonresponders located sites can overcome the shortcomings of scaling and root planning (SRP) therapy. The purpose of this split-mouth study, was to evaluate the clinical and microbiological effects, in short time, the chlorhexidine gel 0.2% in control of subgingival plaque in 20 patients with chronic periodontitis previously treated with SRP. All 4 patients had residual periodontal pockets with probing depth (PD) ≥ 5 mm and bleeding on probing and were randomly divided into groups: negative control (C), positive control (SRP), SRP + chlorhexidine (SRPC) and chlorhexidine test (CLX). The visible plaque index (PI), gingival bleeding index (GI), probing depth (PD), bleeding on probing (BOP), gingival recession (GR) and clinical attachment level (CAL) clinical parameters were evaluated by a calibrated and trained researcher who performed the periodontal monitoring at baseline, 30, 90 and 180 days after treatments. The presence of periodontal pathogens Aggregatibacter actinomycetemcomitans (Aa), Porphyromonas gingivalis (Pg), Prevotella intermedia (Pi) and Tannerella forsythia (Tf) was assessed by means of PRC. Data were statistically analyzed by softawe Boestat 5.0. The level of significance was 5%. Six months after treatment, PI and GI reduced for all groups (p <0.05); SRP, SRPC and CLX groups showed a reduction in BOP and also significantly reduced the BOP when compared to C (p <0.05). The PD was reduced to SRP, SRPC and CLX (p <0.05) groups; CAL increased for SRPC and SRP (p <0.05) and GR increased to SRP C and CLX (p <0.05). The SRPC and CLX groups showed significant reduction in the percentage of sites with presence of some bacteria (p <0.05). The RARC group showed the lowest prevalence of bacteria compared differences between groups. The use of chlorhexidine gel with microbrush, with or without the SRP, as an alternative for the treatment of residual periodontal pockets promotes microbiological benefits without providing significant clinical changes. |
publishDate |
2015 |
dc.date.issued.fl_str_mv |
2015-02-23 |
dc.date.accessioned.fl_str_mv |
2016-01-28T12:58:02Z |
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publishedVersion |
dc.identifier.citation.fl_str_mv |
GONCALVES, Elonice Melo de Sousa. Avaliação clínica da aplicação local de gel de lorexidina com microbrush no tratamento de bolsas periodontais residuais. 2015. 58 f. Tese (Doutorado em Biologia Oral) - Universidade do Sagrado Coração, Bauru, 2015. |
dc.identifier.uri.fl_str_mv |
http://tede2.usc.br:8080/jspui/handle/tede/282 |
identifier_str_mv |
GONCALVES, Elonice Melo de Sousa. Avaliação clínica da aplicação local de gel de lorexidina com microbrush no tratamento de bolsas periodontais residuais. 2015. 58 f. Tese (Doutorado em Biologia Oral) - Universidade do Sagrado Coração, Bauru, 2015. |
url |
http://tede2.usc.br:8080/jspui/handle/tede/282 |
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