Análise em larga escala de elementos transponíveis em genomas de peixes

• Ano de defesa: 2023
• Autor(a) principal: Rudnik, Lorena Maria
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso embargado
• Idioma: por
• Instituição de defesa: Universidade Tecnológica Federal do Paraná; Cornelio Procopio; Brasil; Programa de Pós-Graduação em Bioinformática; UTFPR
• Palavras-chave em Português: Bioinformática; Genoma; Peixes - Fisiologia; Bioinformatics; Genomes; Fishes - Physiology; CNPQ::CIENCIAS SOCIAIS APLICADAS; Engenharia/Tecnologia/Gestão
• Link de acesso: http://repositorio.utfpr.edu.br/jspui/handle/1/32986

Transposable elements (TE) have been widely studied due to their diversity and abundance in the genomes of various species, and their impact on genomic variability and functional role. The presence of TEs in fish may also have implications for the conservation and management of threatened species, as these elements can affect the genomic stability and general health of animals. Even though we are in the era of massive data, quality and large-scale information on ET in fish is poor, whether due to quantity or data curation. In this sense, in order to fill this gap, this research aims to analyze the large-scale annotation of transposable elements in 168 complete fish genomes. To achieve this objective, a pipeline was created with different approaches to cover different strategies for annotating elements. The results obtained in this study provide important information for functional and evolutionary studies of the role of TEs in fish. With the bibliographic review we obtained answers from tools and databases used in research on the same theme. With the workflow created, using three tools, and comparing with the FISHTEDB database and Hilsdorf's research, we found a total of 107,866 elements in 168 species of fish. It is important to highlight that the work was supported by NAPI Bioinformatics via Fundação Araucária through agreement 66/2021.