Estudo do sono em pacientes com DPOC submetidos a um programa de reabilitação pulmonar domiciliar

• Ano de defesa: 2016
• Autor(a) principal: Oliveira, Julio Cesar Mendes de
• Orientador(a): Oliveira, Luis Vicente Franco de
• Banca de defesa: Oliveira, Luis Vicente Franco de, Jorge, Luciana Maria Malosá Sampaio, Vieira, Rodolfo de Paula, Stirbulov, Roberto, Nacif, Sergio Roberto
• Tipo de documento: Tese
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Nove de Julho
• Programa de Pós-Graduação: Programa de Pós-Graduação em Ciências da Reabilitação
• Departamento: Saúde
• País: Brasil
• Palavras-chave em Português: DPOC; distúrbios respiratórios do sono; apneia obstrutiva do sono; overlap síndrome; reabilitação pulmonar; epidemiologia
• Palavras-chave em Inglês: COPD; sleep-related disorders; obstructive sleep apnea; overlap syndrome; pulmonar rehabilitation; epidemiology
• Área do conhecimento CNPq: CIENCIAS DA SAUDE
• Link de acesso: http://bibliotecatede.uninove.br/handle/tede/1901

Introduction: Currently, chronic obstructive pulmonary disease (COPD) is considered an important cause of morbidity and mortality, and the twelfth most prevalent disease in the world, thus representing a serious public health problem. It is common for patients with COPD to have poor sleep quality. As causes of this poor quality of sleep we highlight nocturnal cough, dyspnea, use of medications such as theophylline and recurrent hypoxemia. The term overlap syndrome is used when we have COPD associated with obstructive sleep apnea (OSA). Overlap syndrome, with a prevalence of 9.5-28%, results in marked hypoxemia during sleep with a greater tendency to hypercapnia, pulmonary hypertension and cor pulmonale, giving these patients a worse prognosis. Objectives: To verify the prevalence of overlap syndrome and to analyze the physiological sleep variables and the quality of life of patients with COPD undergoing a home pulmonary rehabilitation program (PRPD). The study will be conducted in a private clinic, located in the city of Cascavel in the interior of the state of Paraná (PR). Patients will be submitted to clinical evaluation, pulmonary function tests (plethysmography), polysomnography and will respond to quality of life questionnaires, excessive daytime sleepiness and risk for OSA before and after participation in PRPD. Results: The main cause related to the development of COPD was current or previous smoking (83.3% of cases). The most frequent symptom reported was dyspnea (88.8%), followed by productive cough (66.6%) and bronchial secretion (40.0%). By evaluating the clinical history of the cases, a significant number of comorbidities were identified, in addition to COPD, and cardiovascular and neurological diseases were more prevalent. The prevalence of OSA with AHI greater than 5 events was 59.3% (70 patients) and AHI> 15 was 26.2% (31 patients). Conclusion: According to the preliminary data, it was possible to delineate the profile of COPD patients associated with a high prevalence of OSA, with characteristics of an elderly population with multiple comorbidities, suggesting a sleep quality lower than desired.