Avaliação da formação de biofilme sobre resina odontológica irradiada com 403 NM contendo nanopartículas de prata
Ano de defesa: | 2020 |
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Autor(a) principal: | |
Orientador(a): | |
Banca de defesa: | , , , , |
Tipo de documento: | Tese |
Tipo de acesso: | Acesso aberto |
Idioma: | por |
Instituição de defesa: |
Universidade Nove de Julho
|
Programa de Pós-Graduação: |
Programa de Pós-Graduação em Biofotônica Aplicada às Ciências da Saúde
|
Departamento: |
Saúde
|
País: |
Brasil
|
Palavras-chave em Português: | |
Palavras-chave em Inglês: | |
Área do conhecimento CNPq: | |
Link de acesso: | http://bibliotecatede.uninove.br/handle/tede/2640 |
Resumo: | The acrylic resin used in the construction of oral prostheses is highly colonized by Candida albicans. The difficulty in hygiene, especially of the prostheses type protocol bolted on implants, favors the emergence of oral candidiasis. This study evaluated the in vitro antifungal effect of incorporation of nanoparticles of silver (AgNPs) in samples of acrylic resin of methyl methacrylate irradiated by LED light and also the mechanical properties of this new material. The AgNPs were synthesized by the reduction of silver nitrate and sodium boroidreto in aqueous solution. The samples impregnated with the AgNPs, were obtained by means of cylindrical metal matrices in the dimensions of 12 mm in diameter by 3 mm in height. The solution containing the AgNPs was added to the liquid component of acrylic resin in concentrations of 0% as control, 2%, 4% and 8%, based on the mass of the polymer resin. This mixture was included in silicone molds and pressed in muffle. The samples were infected with strains of Candida albicans and the group with 8% was irradiated with a LED light source of 403nm at three different times, 60, 180 and 300 seconds, to evaluate its effect on the AgNPs. Mechanical tests of elasticity were also performed. Conclusion: With the concentrations of AgNPs used, there were no changes in any of the antifungal groups, even those where the samples were treated with the LED light. Mechanically, the group impregnated with 2% of AgNPs showed a slight increase in the Modulus of elasticity. |
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Serra, Andrey Jorgehttp://lattes.cnpq.br/6499058447489317Serra, Andrey Jorgehttp://lattes.cnpq.br/6499058447489317Marcos, Rodrigo Labathttp://lattes.cnpq.br/2964112163504080Silva, Daniela de Fátima Teixeira dahttp://lattes.cnpq.br/5912729434641689Leal Junior, Ernesto Cesar Pintohttp://lattes.cnpq.br/8166626486201116Kato, Ilka Tiemyhttp://lattes.cnpq.br/2483797682443241http://lattes.cnpq.br/2264058773694759Moraes, Alexandre Bergamo2021-11-03T21:25:31Z2020-03-26Moraes, Alexandre Bergamo. Avaliação da formação de biofilme sobre resina odontológica irradiada com 403 NM contendo nanopartículas de prata. 2020. 47 f. Tese( Programa de Pós-Graduação em Biofotônica Aplicada às Ciências da Saúde) - Universidade Nove de Julho, São Paulo.http://bibliotecatede.uninove.br/handle/tede/2640The acrylic resin used in the construction of oral prostheses is highly colonized by Candida albicans. The difficulty in hygiene, especially of the prostheses type protocol bolted on implants, favors the emergence of oral candidiasis. This study evaluated the in vitro antifungal effect of incorporation of nanoparticles of silver (AgNPs) in samples of acrylic resin of methyl methacrylate irradiated by LED light and also the mechanical properties of this new material. The AgNPs were synthesized by the reduction of silver nitrate and sodium boroidreto in aqueous solution. The samples impregnated with the AgNPs, were obtained by means of cylindrical metal matrices in the dimensions of 12 mm in diameter by 3 mm in height. The solution containing the AgNPs was added to the liquid component of acrylic resin in concentrations of 0% as control, 2%, 4% and 8%, based on the mass of the polymer resin. This mixture was included in silicone molds and pressed in muffle. The samples were infected with strains of Candida albicans and the group with 8% was irradiated with a LED light source of 403nm at three different times, 60, 180 and 300 seconds, to evaluate its effect on the AgNPs. Mechanical tests of elasticity were also performed. Conclusion: With the concentrations of AgNPs used, there were no changes in any of the antifungal groups, even those where the samples were treated with the LED light. Mechanically, the group impregnated with 2% of AgNPs showed a slight increase in the Modulus of elasticity.A resina acrílica utilizada na construção de próteses orais é altamente colonizada por Candida albicans. A dificuldade na higiene, especialmente das próteses tipo protocolo parafusadas sobre implantes, favorece o aparecimento da candidíase oral. Este trabalho in vitro, avaliou o efeito antifúngico da incorporação de nanopartículas de prata (AgNPs) em amostras de resina acrílica de metil metacrilato irradiadas por luz LED e também as propriedades mecânicas deste novo material. As AgNPs foram sintetizadas pela redução do nitrato de prata e boroidreto de sódio em solução aquosa. As amostras impregnadas com as AgNPs, foram obtidas através de matrizes metálicas cilíndricas nas dimensões de 12 mm de diâmetro por 3 mm de altura. A solução contendo as AgNPs foi adicionada ao componente líquido da resina acrílica nas concentrações de 0% (0 ml), como controle e 2% (0,75 ml), 4% (1,5 ml) e 8% (3 ml), baseadas na massa de 28 g (38 ml) do polímero da resina. Essa mistura foi incluída em moldes de silicona e prensadas em mufla. As amostras foram infectadas por cepas de Candida albicans e o grupo 4 foi irradiado com uma fonte de luz LED de 403nm em três tempos diferentes, 60, 180 e 300 s, para avaliar seu efeito sobre as AgNPs. Testes mecânicos de elasticidade também foram realizados. Conclusão: Com as concentrações de AgNPs utilizadas, não aconteceram alterações antifúngicas em nenhum dos grupos, nem mesmo naqueles onde as amostras foram tratadas com a luz LED. Mecanicamente, o grupo impregnado com 2% de AgNPs mostrou discreto aumento do módulo de elasticidade.Submitted by Nadir Basilio (nadirsb@uninove.br) on 2021-11-03T21:25:31Z No. of bitstreams: 1 Alexandre Bérgamo Moraes.pdf: 981322 bytes, checksum: 3211414de2b19d7a446e143d649f0c9a (MD5)Made available in DSpace on 2021-11-03T21:25:31Z (GMT). No. of bitstreams: 1 Alexandre Bérgamo Moraes.pdf: 981322 bytes, checksum: 3211414de2b19d7a446e143d649f0c9a (MD5) Previous issue date: 2020-03-26application/pdfporUniversidade Nove de JulhoPrograma de Pós-Graduação em Biofotônica Aplicada às Ciências da SaúdeUNINOVEBrasilSaúdenanopartículas de prataresina da base das dentadurasterapia fotodinâmica antimicrobianaefeito antifúngicosilver nanoparticlesdenture base acrylicphotodynamic therapyantifungal effectCIENCIAS DA SAUDEAvaliação da formação de biofilme sobre resina odontológica irradiada com 403 NM contendo nanopartículas de pratainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/doctoralThesis8765449414823306929600info:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da Uninoveinstname:Universidade Nove de Julho (UNINOVE)instacron:UNINOVEORIGINALAlexandre Bérgamo Moraes.pdfAlexandre Bérgamo Moraes.pdfapplication/pdf981322http://localhost:8080/tede/bitstream/tede/2640/2/Alexandre+B%C3%A9rgamo+Moraes.pdf3211414de2b19d7a446e143d649f0c9aMD52LICENSElicense.txtlicense.txttext/plain; charset=utf-82165http://localhost:8080/tede/bitstream/tede/2640/1/license.txtbd3efa91386c1718a7f26a329fdcb468MD51tede/26402021-11-03 19:25:31.578oai:localhost: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Biblioteca Digital de Teses e Dissertaçõeshttp://bibliotecatede.uninove.br/PRIhttp://bibliotecatede.uninove.br/oai/requestbibliotecatede@uninove.br||bibliotecatede@uninove.bropendoar:2021-11-03T21:25:31Biblioteca Digital de Teses e Dissertações da Uninove - Universidade Nove de Julho (UNINOVE)false |
dc.title.por.fl_str_mv |
Avaliação da formação de biofilme sobre resina odontológica irradiada com 403 NM contendo nanopartículas de prata |
title |
Avaliação da formação de biofilme sobre resina odontológica irradiada com 403 NM contendo nanopartículas de prata |
spellingShingle |
Avaliação da formação de biofilme sobre resina odontológica irradiada com 403 NM contendo nanopartículas de prata Moraes, Alexandre Bergamo nanopartículas de prata resina da base das dentaduras terapia fotodinâmica antimicrobiana efeito antifúngico silver nanoparticles denture base acrylic photodynamic therapy antifungal effect CIENCIAS DA SAUDE |
title_short |
Avaliação da formação de biofilme sobre resina odontológica irradiada com 403 NM contendo nanopartículas de prata |
title_full |
Avaliação da formação de biofilme sobre resina odontológica irradiada com 403 NM contendo nanopartículas de prata |
title_fullStr |
Avaliação da formação de biofilme sobre resina odontológica irradiada com 403 NM contendo nanopartículas de prata |
title_full_unstemmed |
Avaliação da formação de biofilme sobre resina odontológica irradiada com 403 NM contendo nanopartículas de prata |
title_sort |
Avaliação da formação de biofilme sobre resina odontológica irradiada com 403 NM contendo nanopartículas de prata |
author |
Moraes, Alexandre Bergamo |
author_facet |
Moraes, Alexandre Bergamo |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Serra, Andrey Jorge |
dc.contributor.advisor1Lattes.fl_str_mv |
http://lattes.cnpq.br/6499058447489317 |
dc.contributor.referee1.fl_str_mv |
Serra, Andrey Jorge |
dc.contributor.referee1Lattes.fl_str_mv |
http://lattes.cnpq.br/6499058447489317 |
dc.contributor.referee2.fl_str_mv |
Marcos, Rodrigo Labat |
dc.contributor.referee2Lattes.fl_str_mv |
http://lattes.cnpq.br/2964112163504080 |
dc.contributor.referee3.fl_str_mv |
Silva, Daniela de Fátima Teixeira da |
dc.contributor.referee3Lattes.fl_str_mv |
http://lattes.cnpq.br/5912729434641689 |
dc.contributor.referee4.fl_str_mv |
Leal Junior, Ernesto Cesar Pinto |
dc.contributor.referee4Lattes.fl_str_mv |
http://lattes.cnpq.br/8166626486201116 |
dc.contributor.referee5.fl_str_mv |
Kato, Ilka Tiemy |
dc.contributor.referee5Lattes.fl_str_mv |
http://lattes.cnpq.br/2483797682443241 |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/2264058773694759 |
dc.contributor.author.fl_str_mv |
Moraes, Alexandre Bergamo |
contributor_str_mv |
Serra, Andrey Jorge Serra, Andrey Jorge Marcos, Rodrigo Labat Silva, Daniela de Fátima Teixeira da Leal Junior, Ernesto Cesar Pinto Kato, Ilka Tiemy |
dc.subject.por.fl_str_mv |
nanopartículas de prata resina da base das dentaduras terapia fotodinâmica antimicrobiana efeito antifúngico |
topic |
nanopartículas de prata resina da base das dentaduras terapia fotodinâmica antimicrobiana efeito antifúngico silver nanoparticles denture base acrylic photodynamic therapy antifungal effect CIENCIAS DA SAUDE |
dc.subject.eng.fl_str_mv |
silver nanoparticles denture base acrylic photodynamic therapy antifungal effect |
dc.subject.cnpq.fl_str_mv |
CIENCIAS DA SAUDE |
description |
The acrylic resin used in the construction of oral prostheses is highly colonized by Candida albicans. The difficulty in hygiene, especially of the prostheses type protocol bolted on implants, favors the emergence of oral candidiasis. This study evaluated the in vitro antifungal effect of incorporation of nanoparticles of silver (AgNPs) in samples of acrylic resin of methyl methacrylate irradiated by LED light and also the mechanical properties of this new material. The AgNPs were synthesized by the reduction of silver nitrate and sodium boroidreto in aqueous solution. The samples impregnated with the AgNPs, were obtained by means of cylindrical metal matrices in the dimensions of 12 mm in diameter by 3 mm in height. The solution containing the AgNPs was added to the liquid component of acrylic resin in concentrations of 0% as control, 2%, 4% and 8%, based on the mass of the polymer resin. This mixture was included in silicone molds and pressed in muffle. The samples were infected with strains of Candida albicans and the group with 8% was irradiated with a LED light source of 403nm at three different times, 60, 180 and 300 seconds, to evaluate its effect on the AgNPs. Mechanical tests of elasticity were also performed. Conclusion: With the concentrations of AgNPs used, there were no changes in any of the antifungal groups, even those where the samples were treated with the LED light. Mechanically, the group impregnated with 2% of AgNPs showed a slight increase in the Modulus of elasticity. |
publishDate |
2020 |
dc.date.issued.fl_str_mv |
2020-03-26 |
dc.date.accessioned.fl_str_mv |
2021-11-03T21:25:31Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/doctoralThesis |
format |
doctoralThesis |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
Moraes, Alexandre Bergamo. Avaliação da formação de biofilme sobre resina odontológica irradiada com 403 NM contendo nanopartículas de prata. 2020. 47 f. Tese( Programa de Pós-Graduação em Biofotônica Aplicada às Ciências da Saúde) - Universidade Nove de Julho, São Paulo. |
dc.identifier.uri.fl_str_mv |
http://bibliotecatede.uninove.br/handle/tede/2640 |
identifier_str_mv |
Moraes, Alexandre Bergamo. Avaliação da formação de biofilme sobre resina odontológica irradiada com 403 NM contendo nanopartículas de prata. 2020. 47 f. Tese( Programa de Pós-Graduação em Biofotônica Aplicada às Ciências da Saúde) - Universidade Nove de Julho, São Paulo. |
url |
http://bibliotecatede.uninove.br/handle/tede/2640 |
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por |
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por |
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8765449414823306929 |
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600 |
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openAccess |
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Universidade Nove de Julho |
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Programa de Pós-Graduação em Biofotônica Aplicada às Ciências da Saúde |
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UNINOVE |
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Brasil |
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Saúde |
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Universidade Nove de Julho |
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