Interações entre o Chronic Mild Stress e o desempenho operante: uma replicação de Dolabela (2004)

• Ano de defesa: 2005
• Autor(a) principal: Rodrigues, Marcelo Barbosa
• Orientador(a): Sério, Tereza Maria de Azevedo Pires
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Pontifícia Universidade Católica de São Paulo
• Programa de Pós-Graduação: Programa de Estudos Pós-Graduados em Psicologia Experimental: Análise do Comportamento
• Departamento: Psicologia
• País: BR
• Palavras-chave em Português: Desamparo aprendido; Esquema concorrente; Psicologia experimental
• Área do conhecimento CNPq: CNPQ::CIENCIAS HUMANAS::PSICOLOGIA::PSICOLOGIA EXPERIMENTAL
• Link de acesso: https://tede2.pucsp.br/handle/handle/16808

Chronic Mild Stress is an experimental animal model of induced anedony, through the exposure of rats to a stressors protocol for a long period of time. Dolabela (2004) investigated interactions between operant performance and Chronic Mild Stress with the objective of verify if the exposure of rats to operant sessions of concurrent schedules FR water FR sacarosis, of the same value, during the stressors protocol, would produce alterations on: a) the corporal weight of the subjects; b) in the intake of water and sacarosis, measured through weekly intake and preference of liquid tests; c) in the number of responses of lever pressing emitted during operant sessions comparing the number of responses emitted before, during and after the stressors protocol. This study had the objective of replicating the work of Dolabela (2004), adding: a) the realization of daily measures of the intake of liquid and food, to investigate possible relationships between weight loss and intake alterations; and b) a concurrent schedule of smaller value (FR5) to some subjects exposed to operant sessions, to evaluate possible effects in terms of response cost, involved in concurrent schedules (FR5 FR5 x FR15 FR15) with respect to the attenuation of the effects of the exposure to the stressors protocol. This work had three experimental conditions: liquid intake and preference test, operant sessions in concurrent schedule and stressors protocol for six weeks. All subjects were submitted to the liquid intake and preference test. Four subjects served as control, of which two were submitted to operant sessions. Eight subjects were exposed to the stressors protocol, of which two were exposed to operant sessions. Of these eight subjects, two were exposed to operant sessions before and after the stressors protocol and four subjects were exposed to the operant sessions before, during and after the protocol, and different FR values were used for each subject (FR5 x FR15). The results show mainly that: 1) The changes on the daily intake of water and food was due to the beginning of water deprivation only; and 2) The FR value seemed to interfere on the recovery of intake and preference for sacarosis after the exposure to the stressors protocol