Avaliação da ocorrência de hanseníase entre os contatos intradomiciliares de pacientes diagnosticados em 2012 no Município de João Pessao/PB

Detalhes bibliográficos
Ano de defesa: 2015
Autor(a) principal: Trindade, Luciana Cavalcante lattes
Orientador(a): Pereira, Luiz Alberto Amador lattes
Banca de defesa: Pereira, Luiz Alberto Amador, Braga, Alfésio Luís Ferreira, Tavares, Mariana
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Católica de Santos
Programa de Pós-Graduação: Mestrado em Saúde Coletiva
Departamento: Centro de Ciências Sociais Aplicadas e Saúde
País: Brasil
Palavras-chave em Português:
Área do conhecimento CNPq:
Link de acesso: https://tede.unisantos.br/handle/tede/1421
Resumo: Leprosy remains a public health problem in Brazil. Despite the improvement in epidemiological indicators, case detection rate remains high in the country. Studies show that household contacts of leprosy patients are the group with the highest risk of developing the disease and the monitoring of contacts is among the priority actions for early diagnosis and control of disease in the country. General Objective: To evaluate the occurrence of leprosy among household contacts of patients diagnosed in 2012 in João Pessoa / PB. Method and sample: Observational study, crosssectional, whose population were household contacts of new leprosy cases diagnosed in 2012 in João Pessoa / PB. Research assistants conducted household interviews - using a pre-tested form containing the variables of interest - and they did physical examination of contacts, to search for lesions suggestive of leprosy and BCG scar. A descriptive analysis of all variables was made; the association between two qualitative variables was verified by the chi-square test; logistic regression models were applied to investigate possible risk factors; we adopted the 0.05 significance level. All ethical aspects were respected. Results: One hundred and ninety contacts related to 72 index cases were interviewed. The prevalence rate of leprosy cases among contacts was 9/191 people (4.7%). In the socioeconomic and demographic data, there was a female predominance (61.1%); the median age was 33 years; most were single (59.5%); nearly 85% had some degree of education; the most common race was white (52.6%); family income was between one and five minimum wages in almost 95% of households; the most common occupation was student (33.7%). In assessing contacts diagnosed with leprosy, leprosy borderline predominated (62.5%), multibacillary (87.5%) and the disability grade one (50.0%) were most common. On four occasions, the operational form was equal to the case and the contact. In the other, the contact showed a multibacillary, while the index case was paucibacillary. Sixty-three percent of the contacts mentioned were invited to attend the health unit, 52.1% attended and 52.4% were instructed to receive the BCG. The majority had some vaccination scar, and 73.1% had only one. Half of contacts who developed the disease had a BCG scar and the other half did not have any. Together, the factors associated with the risk of developing leprosy were the absence of vaccination with BCG and the chronic use of medications. Discussion and Conclusions: The incidence of leprosy among contacts was high and it was similar to that found by other authors. Failures were noted in the surveillance activities by health facilities. The control measures of contacts established by the Ministry of Health and the compatible strategies with local endemic variations and education of the population may bring an adequate coverage of contacts, improving detection and preventing disability and reducing the stigma related to diagnosis lateonset disease.
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spelling Pereira, Luiz Alberto Amadorhttp://lattes.cnpq.br/3924547991056811Martins, Lourdes Conceiçãohttp://lattes.cnpq.br/6226806718300375Pereira, Luiz Alberto AmadorBraga, Alfésio Luís FerreiraTavares, Mariana981.392.744-53http://lattes.cnpq.br/1489868998103147Trindade, Luciana Cavalcante2015-05-06T18:11:48Z2015-02-23TRINDADE, Luciana Cavalcante. Avaliação da ocorrência de hanseníase entre os contatos intradomiciliares de pacientes diagnosticados em 2012 no Município de João Pessao/PB. 2015. 115 f. Dissertação (mestrado) - Universidade Católica de Santos, Santos, 2015https://tede.unisantos.br/handle/tede/1421Leprosy remains a public health problem in Brazil. Despite the improvement in epidemiological indicators, case detection rate remains high in the country. Studies show that household contacts of leprosy patients are the group with the highest risk of developing the disease and the monitoring of contacts is among the priority actions for early diagnosis and control of disease in the country. General Objective: To evaluate the occurrence of leprosy among household contacts of patients diagnosed in 2012 in João Pessoa / PB. Method and sample: Observational study, crosssectional, whose population were household contacts of new leprosy cases diagnosed in 2012 in João Pessoa / PB. Research assistants conducted household interviews - using a pre-tested form containing the variables of interest - and they did physical examination of contacts, to search for lesions suggestive of leprosy and BCG scar. A descriptive analysis of all variables was made; the association between two qualitative variables was verified by the chi-square test; logistic regression models were applied to investigate possible risk factors; we adopted the 0.05 significance level. All ethical aspects were respected. Results: One hundred and ninety contacts related to 72 index cases were interviewed. The prevalence rate of leprosy cases among contacts was 9/191 people (4.7%). In the socioeconomic and demographic data, there was a female predominance (61.1%); the median age was 33 years; most were single (59.5%); nearly 85% had some degree of education; the most common race was white (52.6%); family income was between one and five minimum wages in almost 95% of households; the most common occupation was student (33.7%). In assessing contacts diagnosed with leprosy, leprosy borderline predominated (62.5%), multibacillary (87.5%) and the disability grade one (50.0%) were most common. On four occasions, the operational form was equal to the case and the contact. In the other, the contact showed a multibacillary, while the index case was paucibacillary. Sixty-three percent of the contacts mentioned were invited to attend the health unit, 52.1% attended and 52.4% were instructed to receive the BCG. The majority had some vaccination scar, and 73.1% had only one. Half of contacts who developed the disease had a BCG scar and the other half did not have any. Together, the factors associated with the risk of developing leprosy were the absence of vaccination with BCG and the chronic use of medications. Discussion and Conclusions: The incidence of leprosy among contacts was high and it was similar to that found by other authors. Failures were noted in the surveillance activities by health facilities. The control measures of contacts established by the Ministry of Health and the compatible strategies with local endemic variations and education of the population may bring an adequate coverage of contacts, improving detection and preventing disability and reducing the stigma related to diagnosis lateonset disease.A hanseníase permanece como um problema de saúde pública no Brasil e, apesar da melhoria nos indicadores epidemiológicos, a detecção mantém-se alta no país. Estudos comprovam que os contatos intradomiciliares dos doentes constituem o grupo de maior risco de desenvolver a doença e a vigilância dos contatos está entre as ações prioritárias para o diagnóstico precoce e o controle da endemia no país. Objetivo geral: Avaliar a ocorrência de casos de hanseníase entre os contatos intradomiciliares dos pacientes diagnosticados em 2012, em João Pessoa/PB. Método e casuística: Estudo observacional, transversal, cuja população foram os contatos intradomiciliares dos casos novos de hanseníase diagnosticados no ano de 2012, em João Pessoa/PB. Assistentes de pesquisa realizaram entrevistas domiciliares - utilizando um formulário pré-testado, contendo as variáveis de interesse - e o exame físico dos contatos, buscando lesões sugestivas de hanseníase e cicatriz de BCG. Foi feita a análise descritiva de todas as variáveis; verificou-se a associação entre duas variáveis qualitativas pelo teste do quiquadrado; aplicaram-se modelos de regressão logística para averiguar possíveis fatores de risco; foi adotado o nível de significância de 0,05. Todos os aspectos éticos foram respeitados. Resultados: Entrevistaram-se 190 contatos relacionados a 72 casos índices. A prevalência de casos de hanseníase entre os contatos foi de 9/191 pessoas (4,7%). No perfil socioeconômico e demográfico, houve predomínio do sexo feminino (61,1%); a idade mediana foi de 33 anos; a maioria era solteira (59,5%); quase 85% apresentava algum grau de escolaridade; a raça mais comum foi a branca (52,6%); a renda familiar foi de um a cinco salários-mínimos em quase 95% das famílias; a profissão mais comum foi a de estudante (33,7%). Na avaliação dos contatos diagnosticados com hanseníase, predominou a forma clínica dimorfa (62,5%), a operacional multibacilar (87,5%) e o grau um de incapacidade física (50,0%). Em quatro situações, a forma operacional foi igual para o caso e o contato. Nas demais, o contato apresentou uma forma multibacilar, enquanto o caso índice era paucibacilar. Sessenta e três por cento dos contatos referiram que foram convidados a comparecer à unidade de saúde, 52,1% compareceram e 52,4% foram orientados a receber a BCG. A maioria apresentava alguma cicatriz vacinal, sendo que 73,1% apresentavam apenas uma. Metade dos contatos que desenvolveu a doença tinha uma cicatriz vacinal e a outra metade não apresentava nenhuma. Os fatores que, em conjunto, associaram-se ao risco de desenvolver a hanseníase foram a ausência da vacinação BCG e o uso crônico de medicações. Discussão e Conclusões: A ocorrência de hanseníase entre os contatos do estudo foi elevada e semelhante à encontrada por outros autores. Foram percebidas falhas nas ações de vigilância desenvolvidas nas unidades de saúde. As medidas de controle dos contatos estabelecidas pelo Ministério da Saúde, além de estratégias compatíveis com as variações locais de endemicidade e de escolaridade da população, poderão trazer uma cobertura adequada dos contatos, melhorando a detecção e prevenindo incapacidades e diminuindo o estigma relacionado ao diagnóstico tardio da doença.application/pdfporUniversidade Católica de SantosMestrado em Saúde ColetivaCatólica de SantosBrasilCentro de Ciências Sociais Aplicadas e SaúdeTRINDADE, Luciana Cavalcante. Avaliação da ocorrência de hanseníase entre os contatos intradomiciliares de pacientes diagnosticados em 2012 no Município de João Pessao/PB. 2015. 115 f. 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dc.title.por.fl_str_mv Avaliação da ocorrência de hanseníase entre os contatos intradomiciliares de pacientes diagnosticados em 2012 no Município de João Pessao/PB
title Avaliação da ocorrência de hanseníase entre os contatos intradomiciliares de pacientes diagnosticados em 2012 no Município de João Pessao/PB
spellingShingle Avaliação da ocorrência de hanseníase entre os contatos intradomiciliares de pacientes diagnosticados em 2012 no Município de João Pessao/PB
Trindade, Luciana Cavalcante
hanseníase; doenças negligenciadas; saúde pública; vacina BCG
SAUDE COLETIVA::SAUDE PUBLICA
title_short Avaliação da ocorrência de hanseníase entre os contatos intradomiciliares de pacientes diagnosticados em 2012 no Município de João Pessao/PB
title_full Avaliação da ocorrência de hanseníase entre os contatos intradomiciliares de pacientes diagnosticados em 2012 no Município de João Pessao/PB
title_fullStr Avaliação da ocorrência de hanseníase entre os contatos intradomiciliares de pacientes diagnosticados em 2012 no Município de João Pessao/PB
title_full_unstemmed Avaliação da ocorrência de hanseníase entre os contatos intradomiciliares de pacientes diagnosticados em 2012 no Município de João Pessao/PB
title_sort Avaliação da ocorrência de hanseníase entre os contatos intradomiciliares de pacientes diagnosticados em 2012 no Município de João Pessao/PB
author Trindade, Luciana Cavalcante
author_facet Trindade, Luciana Cavalcante
author_role author
dc.contributor.advisor1.fl_str_mv Pereira, Luiz Alberto Amador
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/3924547991056811
dc.contributor.advisor-co1.fl_str_mv Martins, Lourdes Conceição
dc.contributor.advisor-co1Lattes.fl_str_mv http://lattes.cnpq.br/6226806718300375
dc.contributor.referee1.fl_str_mv Pereira, Luiz Alberto Amador
dc.contributor.referee2.fl_str_mv Braga, Alfésio Luís Ferreira
dc.contributor.referee3.fl_str_mv Tavares, Mariana
dc.contributor.authorID.fl_str_mv 981.392.744-53
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/1489868998103147
dc.contributor.author.fl_str_mv Trindade, Luciana Cavalcante
contributor_str_mv Pereira, Luiz Alberto Amador
Martins, Lourdes Conceição
Pereira, Luiz Alberto Amador
Braga, Alfésio Luís Ferreira
Tavares, Mariana
dc.subject.por.fl_str_mv hanseníase; doenças negligenciadas; saúde pública; vacina BCG
topic hanseníase; doenças negligenciadas; saúde pública; vacina BCG
SAUDE COLETIVA::SAUDE PUBLICA
dc.subject.cnpq.fl_str_mv SAUDE COLETIVA::SAUDE PUBLICA
description Leprosy remains a public health problem in Brazil. Despite the improvement in epidemiological indicators, case detection rate remains high in the country. Studies show that household contacts of leprosy patients are the group with the highest risk of developing the disease and the monitoring of contacts is among the priority actions for early diagnosis and control of disease in the country. General Objective: To evaluate the occurrence of leprosy among household contacts of patients diagnosed in 2012 in João Pessoa / PB. Method and sample: Observational study, crosssectional, whose population were household contacts of new leprosy cases diagnosed in 2012 in João Pessoa / PB. Research assistants conducted household interviews - using a pre-tested form containing the variables of interest - and they did physical examination of contacts, to search for lesions suggestive of leprosy and BCG scar. A descriptive analysis of all variables was made; the association between two qualitative variables was verified by the chi-square test; logistic regression models were applied to investigate possible risk factors; we adopted the 0.05 significance level. All ethical aspects were respected. Results: One hundred and ninety contacts related to 72 index cases were interviewed. The prevalence rate of leprosy cases among contacts was 9/191 people (4.7%). In the socioeconomic and demographic data, there was a female predominance (61.1%); the median age was 33 years; most were single (59.5%); nearly 85% had some degree of education; the most common race was white (52.6%); family income was between one and five minimum wages in almost 95% of households; the most common occupation was student (33.7%). In assessing contacts diagnosed with leprosy, leprosy borderline predominated (62.5%), multibacillary (87.5%) and the disability grade one (50.0%) were most common. On four occasions, the operational form was equal to the case and the contact. In the other, the contact showed a multibacillary, while the index case was paucibacillary. Sixty-three percent of the contacts mentioned were invited to attend the health unit, 52.1% attended and 52.4% were instructed to receive the BCG. The majority had some vaccination scar, and 73.1% had only one. Half of contacts who developed the disease had a BCG scar and the other half did not have any. Together, the factors associated with the risk of developing leprosy were the absence of vaccination with BCG and the chronic use of medications. Discussion and Conclusions: The incidence of leprosy among contacts was high and it was similar to that found by other authors. Failures were noted in the surveillance activities by health facilities. The control measures of contacts established by the Ministry of Health and the compatible strategies with local endemic variations and education of the population may bring an adequate coverage of contacts, improving detection and preventing disability and reducing the stigma related to diagnosis lateonset disease.
publishDate 2015
dc.date.accessioned.fl_str_mv 2015-05-06T18:11:48Z
dc.date.issued.fl_str_mv 2015-02-23
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.citation.fl_str_mv TRINDADE, Luciana Cavalcante. Avaliação da ocorrência de hanseníase entre os contatos intradomiciliares de pacientes diagnosticados em 2012 no Município de João Pessao/PB. 2015. 115 f. Dissertação (mestrado) - Universidade Católica de Santos, Santos, 2015
dc.identifier.uri.fl_str_mv https://tede.unisantos.br/handle/tede/1421
identifier_str_mv TRINDADE, Luciana Cavalcante. Avaliação da ocorrência de hanseníase entre os contatos intradomiciliares de pacientes diagnosticados em 2012 no Município de João Pessao/PB. 2015. 115 f. Dissertação (mestrado) - Universidade Católica de Santos, Santos, 2015
url https://tede.unisantos.br/handle/tede/1421
dc.language.iso.fl_str_mv por
language por
dc.relation.references.por.fl_str_mv TRINDADE, Luciana Cavalcante. Avaliação da ocorrência de hanseníase entre os contatos intradomiciliares de pacientes diagnosticados em 2012 no Município de João Pessao/PB. 2015. 115 f. Dissertação (mestrado) - Universidade Católica de Santos, Santos, 2015
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Católica de Santos
dc.publisher.program.fl_str_mv Mestrado em Saúde Coletiva
dc.publisher.initials.fl_str_mv Católica de Santos
dc.publisher.country.fl_str_mv Brasil
dc.publisher.department.fl_str_mv Centro de Ciências Sociais Aplicadas e Saúde
publisher.none.fl_str_mv Universidade Católica de Santos
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