Associa??o entre terapia antirretroviral e o risco cardiovascular em pessoas que vivem com HIV/AIDS

Detalhes bibliográficos
Ano de defesa: 2016
Autor(a) principal: Costa, Raphael Silva Nogueira lattes
Orientador(a): Cerqueira, Eneida de Moraes Marc?lio
Banca de defesa: Não Informado pela instituição
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Estadual de Feira de Santana
Programa de Pós-Graduação: Mestrado Acad?mico em Sa?de Coletiva
Departamento: DEPARTAMENTO DE SA?DE
País: Brasil
Palavras-chave em Português:
S?ndrome de Imunodefici?ncia Adquirida
Terapia Antirretroviral de Alta Atividade
Fatores de Risco
Palavras-chave em Inglês:
Acquired Immunodeficiency Syndrome
Antiretroviral Therapy
Highly Active
Risk Factors
Área do conhecimento CNPq:
CIENCIAS DA SAUDE::SAUDE COLETIVA
Link de acesso: http://localhost:8080/tede/handle/tede/562
Resumo: The introduction of highly active antiretroviral therapy (HAART) for the treatment of HIV-infected individuals brought a dramatic change in the natural course of the disease, leading to increased prevalence of diseases not directly related to HIV such as Diabetes Mellitus and cardiovascular diseases in these individuals. In this context, this study aimed to evaluate the impact of HAART on the cardiovascular risk of people living with HIV/AIDS registered in the Municipal Reference Center of Sexually Transmitted Diseases/HIV/AIDS in the municipality of Feira de Santana, Bahia. This cross-sectional study was carried out through analysis of medical records of patients admitted between 2010 and 2014. The data collection form used contained questions relating to sociodemographic factors, cardiovascular risk factors, and characteristics related to HIV infection. Data were analyzed using STATA version 11 for Windows. The results support an association between the use of HAART and increased overall cardiovascular risk. The following factors were also associated with increased overall cardiovascular risk: age >40 years; male; paid employment; smoking; blood pressure ?140/90 mm Hg; cholesterol ? 240 mg/dl; triglycerides ? 200mg/dl; glucose ? 110mg/dl; change in the HAART scheme; and viral load < 10,000 copies/mm3.
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spelling Cerqueira, Eneida de Moraes Marc?lio0410445550401216922560http://lattes.cnpq.br/5314273426058220Costa, Raphael Silva Nogueira2018-01-25T22:45:33Z2016-03-30COSTA, Raphael Silva Nogueira. Associa??o entre terapia antirretroviral e o risco cardiovascular em pessoas que vivem com HIV/AIDS. 2016. 95 f. Disserta??o (Mestrado Acad?mico em Sa?de Coletiva)- Universidade Estadual de Feira de Santana, Feira de Santana, 2016.http://localhost:8080/tede/handle/tede/562The introduction of highly active antiretroviral therapy (HAART) for the treatment of HIV-infected individuals brought a dramatic change in the natural course of the disease, leading to increased prevalence of diseases not directly related to HIV such as Diabetes Mellitus and cardiovascular diseases in these individuals. In this context, this study aimed to evaluate the impact of HAART on the cardiovascular risk of people living with HIV/AIDS registered in the Municipal Reference Center of Sexually Transmitted Diseases/HIV/AIDS in the municipality of Feira de Santana, Bahia. This cross-sectional study was carried out through analysis of medical records of patients admitted between 2010 and 2014. The data collection form used contained questions relating to sociodemographic factors, cardiovascular risk factors, and characteristics related to HIV infection. Data were analyzed using STATA version 11 for Windows. The results support an association between the use of HAART and increased overall cardiovascular risk. The following factors were also associated with increased overall cardiovascular risk: age >40 years; male; paid employment; smoking; blood pressure ?140/90 mm Hg; cholesterol ? 240 mg/dl; triglycerides ? 200mg/dl; glucose ? 110mg/dl; change in the HAART scheme; and viral load < 10,000 copies/mm3.Com a introdu??o da terapia antirretroviral de alta pot?ncia (TARV) no tratamento dos indiv?duos infectados pelo HIV, houve uma dram?tica mudan?a no curso da hist?ria natural da doen?a, traduzida pela maior ocorr?ncia, nestes indiv?duos, de doen?as n?o associadas diretamente ao HIV, a exemplo do diabetes mellitus e daquelas relacionadas ao sistema cardiovascular. Neste contexto, essa pesquisa objetivou avaliar o impacto da TARV sobre o risco cardiovascular, em pessoas que vivem com HIV/Aids cadastradas no Centro de Refer?ncia Municipal em Doen?as Sexualmente Transmiss?veis/HIV/Aids no munic?pio de Feira de Santana - Ba. Foi realizado estudo de corte transversal atrav?s da an?lise dos prontu?rios cl?nicos de 239 pacientes admitidos no per?odo de 2010 a 2014. Foram pesquisadas as caracter?sticas s?cio-demogr?ficas, fatores de risco cardiovascular e caracter?sticas relacionadas ? infec??o pelo HIV. Os dados foram analisados utilizando o software Stata vers?o 11 para Windows. Primeiramente, as vari?veis foram analisadas de forma descritiva, posteriormente, foi realizada a distribui??o das vari?veis segundo o desfecho do estudo (risco cardiovascular baseado do escore de Framingham), para verificar a signific?ncia estat?stica por meio do teste qui-quadrado (5% de signific?ncia). Foi calculado, ainda, a raz?o de preval?ncia (RP) bruta para as vari?veis exposi??o (uso de TARV) e por a vari?vel desfecho, sendo considerado o intervalo de confian?a de 95%. Em continuidade, foi realizada a an?lise multivariada, utilizando o m?todo de Regress?o de Poisson robusta. Os resultados obtidos apontam para a associa??o entre uso de TARV e aumento do risco cardiovascular global. Os seguintes fatores tamb?m se mostraram associados ao aumento do risco cardiovascular global: idade > 40 anos; sexo masculino; ocupa??o remunerada; h?bito de fumar; press?o arterial ? 140x90mmHg; colesterol ? 240mg/dl, triglicer?deos ? 200mg/dl, glicose ?110mg/dl, mudan?a do esquema de TARV e carga viral < 10.000 c?pias/mm3. Os resultados obtidos revelam que fatores socioecon?micos e de risco cardiovascular influenciam no risco cardiovascular global dos indiv?duos vivendo com HIV/Aids.Submitted by Ricardo Cedraz Duque Moliterno (ricardo.moliterno@uefs.br) on 2018-01-25T22:45:33Z No. of bitstreams: 1 DISSERTA??O MESTRADO FINAL CORRIGIDA VERS?O PARA IMPRESSAO.pdf: 3089061 bytes, checksum: a89bf81bdbde36c941d50f434cb617fb (MD5)Made available in DSpace on 2018-01-25T22:45:33Z (GMT). No. of bitstreams: 1 DISSERTA??O MESTRADO FINAL CORRIGIDA VERS?O PARA IMPRESSAO.pdf: 3089061 bytes, checksum: a89bf81bdbde36c941d50f434cb617fb (MD5) Previous issue date: 2016-03-30Conselho Nacional de Pesquisa e Desenvolvimento Cient?fico e Tecnol?gico - CNPqapplication/pdfporUniversidade Estadual de Feira de SantanaMestrado Acad?mico em Sa?de ColetivaUEFSBrasilDEPARTAMENTO DE SA?DES?ndrome de Imunodefici?ncia AdquiridaTerapia Antirretroviral de Alta AtividadeFatores de RiscoAcquired Immunodeficiency SyndromeAntiretroviral TherapyHighly ActiveRisk FactorsCIENCIAS DA SAUDE::SAUDE COLETIVAAssocia??o entre terapia antirretroviral e o risco cardiovascular em pessoas que vivem com HIV/AIDSinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesis-21222253766072083266006006006001006395569471477890-61731671037544951991802873727776104890info:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da UEFSinstname:Universidade Estadual de Feira de Santana (UEFS)instacron:UEFSORIGINALDISSERTA??O MESTRADO FINAL CORRIGIDA VERS?O PARA IMPRESSAO.pdfDISSERTA??O MESTRADO FINAL CORRIGIDA VERS?O PARA IMPRESSAO.pdfapplication/pdf3089061http://tede2.uefs.br:8080/bitstream/tede/562/2/DISSERTA%C3%87%C3%83O+MESTRADO+FINAL+CORRIGIDA+VERS%C3%83O+PARA+IMPRESSAO.pdfa89bf81bdbde36c941d50f434cb617fbMD52LICENSElicense.txtlicense.txttext/plain; charset=utf-82089http://tede2.uefs.br:8080/bitstream/tede/562/1/license.txt7b5ba3d2445355f386edab96125d42b7MD51tede/5622018-01-25 19:45:33.387oai:tede2.uefs.br:8080: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Biblioteca Digital de Teses e Dissertaçõeshttp://tede2.uefs.br:8080/PUBhttp://tede2.uefs.br:8080/oai/requestbcuefs@uefs.br|| bcref@uefs.br||bcuefs@uefs.bropendoar:2018-01-25T22:45:33Biblioteca Digital de Teses e Dissertações da UEFS - Universidade Estadual de Feira de Santana (UEFS)false
dc.title.por.fl_str_mv Associa??o entre terapia antirretroviral e o risco cardiovascular em pessoas que vivem com HIV/AIDS
title Associa??o entre terapia antirretroviral e o risco cardiovascular em pessoas que vivem com HIV/AIDS
spellingShingle Associa??o entre terapia antirretroviral e o risco cardiovascular em pessoas que vivem com HIV/AIDS
Costa, Raphael Silva Nogueira
S?ndrome de Imunodefici?ncia Adquirida
Terapia Antirretroviral de Alta Atividade
Fatores de Risco
Acquired Immunodeficiency Syndrome
Antiretroviral Therapy
Highly Active
Risk Factors
CIENCIAS DA SAUDE::SAUDE COLETIVA
title_short Associa??o entre terapia antirretroviral e o risco cardiovascular em pessoas que vivem com HIV/AIDS
title_full Associa??o entre terapia antirretroviral e o risco cardiovascular em pessoas que vivem com HIV/AIDS
title_fullStr Associa??o entre terapia antirretroviral e o risco cardiovascular em pessoas que vivem com HIV/AIDS
title_full_unstemmed Associa??o entre terapia antirretroviral e o risco cardiovascular em pessoas que vivem com HIV/AIDS
title_sort Associa??o entre terapia antirretroviral e o risco cardiovascular em pessoas que vivem com HIV/AIDS
author Costa, Raphael Silva Nogueira
author_facet Costa, Raphael Silva Nogueira
author_role author
dc.contributor.advisor1.fl_str_mv Cerqueira, Eneida de Moraes Marc?lio
dc.contributor.advisor1ID.fl_str_mv 04104455504
dc.contributor.authorID.fl_str_mv 01216922560
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/5314273426058220
dc.contributor.author.fl_str_mv Costa, Raphael Silva Nogueira
contributor_str_mv Cerqueira, Eneida de Moraes Marc?lio
dc.subject.por.fl_str_mv S?ndrome de Imunodefici?ncia Adquirida
Terapia Antirretroviral de Alta Atividade
Fatores de Risco
topic S?ndrome de Imunodefici?ncia Adquirida
Terapia Antirretroviral de Alta Atividade
Fatores de Risco
Acquired Immunodeficiency Syndrome
Antiretroviral Therapy
Highly Active
Risk Factors
CIENCIAS DA SAUDE::SAUDE COLETIVA
dc.subject.eng.fl_str_mv Acquired Immunodeficiency Syndrome
Antiretroviral Therapy
Highly Active
Risk Factors
dc.subject.cnpq.fl_str_mv CIENCIAS DA SAUDE::SAUDE COLETIVA
description The introduction of highly active antiretroviral therapy (HAART) for the treatment of HIV-infected individuals brought a dramatic change in the natural course of the disease, leading to increased prevalence of diseases not directly related to HIV such as Diabetes Mellitus and cardiovascular diseases in these individuals. In this context, this study aimed to evaluate the impact of HAART on the cardiovascular risk of people living with HIV/AIDS registered in the Municipal Reference Center of Sexually Transmitted Diseases/HIV/AIDS in the municipality of Feira de Santana, Bahia. This cross-sectional study was carried out through analysis of medical records of patients admitted between 2010 and 2014. The data collection form used contained questions relating to sociodemographic factors, cardiovascular risk factors, and characteristics related to HIV infection. Data were analyzed using STATA version 11 for Windows. The results support an association between the use of HAART and increased overall cardiovascular risk. The following factors were also associated with increased overall cardiovascular risk: age >40 years; male; paid employment; smoking; blood pressure ?140/90 mm Hg; cholesterol ? 240 mg/dl; triglycerides ? 200mg/dl; glucose ? 110mg/dl; change in the HAART scheme; and viral load < 10,000 copies/mm3.
publishDate 2016
dc.date.issued.fl_str_mv 2016-03-30
dc.date.accessioned.fl_str_mv 2018-01-25T22:45:33Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
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dc.identifier.citation.fl_str_mv COSTA, Raphael Silva Nogueira. Associa??o entre terapia antirretroviral e o risco cardiovascular em pessoas que vivem com HIV/AIDS. 2016. 95 f. Disserta??o (Mestrado Acad?mico em Sa?de Coletiva)- Universidade Estadual de Feira de Santana, Feira de Santana, 2016.
dc.identifier.uri.fl_str_mv http://localhost:8080/tede/handle/tede/562
identifier_str_mv COSTA, Raphael Silva Nogueira. Associa??o entre terapia antirretroviral e o risco cardiovascular em pessoas que vivem com HIV/AIDS. 2016. 95 f. Disserta??o (Mestrado Acad?mico em Sa?de Coletiva)- Universidade Estadual de Feira de Santana, Feira de Santana, 2016.
url http://localhost:8080/tede/handle/tede/562
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language por
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dc.publisher.none.fl_str_mv Universidade Estadual de Feira de Santana
dc.publisher.program.fl_str_mv Mestrado Acad?mico em Sa?de Coletiva
dc.publisher.initials.fl_str_mv UEFS
dc.publisher.country.fl_str_mv Brasil
dc.publisher.department.fl_str_mv DEPARTAMENTO DE SA?DE
publisher.none.fl_str_mv Universidade Estadual de Feira de Santana
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