A pr?tica regular do futebol: O alto rendimento deste esporte est? associado a danos gen?ticos?

Detalhes bibliográficos
Ano de defesa: 2007
Autor(a) principal: Motta, Marcelo Trotte lattes
Orientador(a): Cerqueira, Eneida de Moraes Marc?lio
Banca de defesa: Não Informado pela instituição
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Estadual de Feira de Santana
Programa de Pós-Graduação: Mestrado Acad?mico em Biotecnologia
Departamento: DEPARTAMENTO DE CI?NCIAS BIOL?GICAS
País: Brasil
Palavras-chave em Português:
Radicais livres
Micron?cleos
Danos ao DNA
Futebol
Palavras-chave em Inglês:
Free radicals
Micronuclei
DNA damage
Soccer
Área do conhecimento CNPq:
CIENCIAS BIOLOGICAS
CIENCIAS BIOLOGICAS::GENETICA
Link de acesso: http://tede2.uefs.br:8080/handle/tede/1206
Resumo: Although physical training has been encouraged as a health-promoting activity, high intensity exercises lead to increased oxidative processes taking place in the mitochondria, thus generating reactive oxygen species, known for inducing DNA damage. This study is aimed at identifying the chromosomal damage in soccer players both during the games and in their physical and technical training programs by means of the Micronucleus Test for lymphocytes following the protocol proposed by Fenech (2000). The sample consisted of three groups: Group I, comprising fifteen soccer players under an intense physical training schedule; Group II, composed of 18 subjects performing physical activities on a regular basis; and Group III with 19 sedentary subjects. The statistical analysis of the number of micronuclei found in the total amount of cells under investigation did not present any significant diferences either in the absolute number of cells with micronuclei or in their mean number: ??2=0.3603; G.L.=2; p> 0.70 and F2,,49 = 0.1185; p= 0.8887, respectively. Results in this experiment conditions do not show the potential for micronucleus analysis to biomonitor subjects under intense physical training and point out the need for further studies before this cytogenetic endpoint becomes a risk biomarker.
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spelling Cerqueira, Eneida de Moraes Marc?lio0410445550441419910582http://lattes.cnpq.br/3989639095741797Motta, Marcelo Trotte2020-08-18T16:47:37Z2007-07-31MOTTA, Marcelo Trotte. A pr?tica regular do futebol: O alto rendimento deste esporte est? associado a danos gen?ticos?. 2007. 75 f. Disserta??o (Mestrado Acad?mico em Biotecnologia)- Universidade Estadual de Feira de Santana, Feira de Santana, 2007.http://tede2.uefs.br:8080/handle/tede/1206Although physical training has been encouraged as a health-promoting activity, high intensity exercises lead to increased oxidative processes taking place in the mitochondria, thus generating reactive oxygen species, known for inducing DNA damage. This study is aimed at identifying the chromosomal damage in soccer players both during the games and in their physical and technical training programs by means of the Micronucleus Test for lymphocytes following the protocol proposed by Fenech (2000). The sample consisted of three groups: Group I, comprising fifteen soccer players under an intense physical training schedule; Group II, composed of 18 subjects performing physical activities on a regular basis; and Group III with 19 sedentary subjects. The statistical analysis of the number of micronuclei found in the total amount of cells under investigation did not present any significant diferences either in the absolute number of cells with micronuclei or in their mean number: ??2=0.3603; G.L.=2; p> 0.70 and F2,,49 = 0.1185; p= 0.8887, respectively. Results in this experiment conditions do not show the potential for micronucleus analysis to biomonitor subjects under intense physical training and point out the need for further studies before this cytogenetic endpoint becomes a risk biomarker.A pr?tica de atividade f?sica tem sido estimulada com o objetivo de beneficiar a sa?de de seus adeptos. Entretanto, exerc?cios de alta intensidade induzem ao aumento dos processos oxidativos que ocorrem nas mitoc?ndrias, resultando, em conseq??ncia, na libera??o de esp?cimes reativos de oxig?nio, reconhecidamente capazes de induzir danos ao DNA. Este estudo objetiva identificar os danos cromoss?micos em jogadores de futebol durante os jogos e no programa de treinamento f?sico-t?cnico atrav?s do Teste de Micron?cleo em linf?citos de acordo com protocolo sugerido por Fenech (2000). A amostra analisada incluiu tr?s grupos de estudo: Grupo I, constitu?do por 15 jogadores de futebol, submetidos a regime intenso de treinamento; Grupo II, formado por 18 indiv?duos que regularmente desenvolvem atividade f?sica e Grupo III composto por 19 indiv?duos com estilo de vida sedent?rio. A an?lise estat?stica dos resultados considerando o n?mero de micron?cleos observado no total de c?lulas analisadas n?o revelou diferen?a significante quer quando considerado o n?mero absoluto de c?lulas com micron?cleos, quer considerando o n?mero m?dio: ??2=0,3603; G.L.=2; p> 0,70 e F2 ,49 = 0,1185; p= 0,8887, respectivamente. Os resultados obtidos nestas condi??es experimentais n?o evidenciam o potencial da an?lise de micron?cleos para o biomonitoramento de indiv?duos submetidos a exerc?cios intensos e ressaltam a necessidade de estudos adicionais antes que este endpoint citogen?tico venha a ser utilizado como biomarcador de risco.Submitted by Bruno Matos Nascimento (brunomatos@uefs.br) on 2020-08-18T16:47:37Z No. of bitstreams: 1 DISSERTA??O MARCELO TROTTE MOTTA.pdf: 2474482 bytes, checksum: 9c76d0518a67bd3c03f5c82dec39ab6d (MD5)Made available in DSpace on 2020-08-18T16:47:37Z (GMT). No. of bitstreams: 1 DISSERTA??O MARCELO TROTTE MOTTA.pdf: 2474482 bytes, checksum: 9c76d0518a67bd3c03f5c82dec39ab6d (MD5) Previous issue date: 2007-07-31application/pdfporUniversidade Estadual de Feira de SantanaMestrado Acad?mico em BiotecnologiaUEFSBrasilDEPARTAMENTO DE CI?NCIAS BIOL?GICASRadicais livresMicron?cleosDanos ao DNAFutebolFree radicalsMicronucleiDNA damageSoccerCIENCIAS BIOLOGICASCIENCIAS BIOLOGICAS::GENETICAA pr?tica regular do futebol: O alto rendimento deste esporte est? associado a danos gen?ticos?info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesis-54735432730516527826006006006005026123383450589282-3439178843068202161-5518144268585252051info:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da UEFSinstname:Universidade Estadual de Feira de Santana (UEFS)instacron:UEFSORIGINALDISSERTA??O MARCELO TROTTE MOTTA.pdfDISSERTA??O MARCELO TROTTE MOTTA.pdfapplication/pdf2474482http://tede2.uefs.br:8080/bitstream/tede/1206/2/DISSERTA%C3%87%C3%83O+MARCELO+TROTTE+MOTTA.pdf9c76d0518a67bd3c03f5c82dec39ab6dMD52LICENSElicense.txtlicense.txttext/plain; charset=utf-82089http://tede2.uefs.br:8080/bitstream/tede/1206/1/license.txt7b5ba3d2445355f386edab96125d42b7MD51tede/12062020-08-18 13:47:37.562oai:tede2.uefs.br:8080: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Biblioteca Digital de Teses e Dissertaçõeshttp://tede2.uefs.br:8080/PUBhttp://tede2.uefs.br:8080/oai/requestbcuefs@uefs.br|| bcref@uefs.br||bcuefs@uefs.bropendoar:2020-08-18T16:47:37Biblioteca Digital de Teses e Dissertações da UEFS - Universidade Estadual de Feira de Santana (UEFS)false
dc.title.por.fl_str_mv A pr?tica regular do futebol: O alto rendimento deste esporte est? associado a danos gen?ticos?
title A pr?tica regular do futebol: O alto rendimento deste esporte est? associado a danos gen?ticos?
spellingShingle A pr?tica regular do futebol: O alto rendimento deste esporte est? associado a danos gen?ticos?
Motta, Marcelo Trotte
Radicais livres
Micron?cleos
Danos ao DNA
Futebol
Free radicals
Micronuclei
DNA damage
Soccer
CIENCIAS BIOLOGICAS
CIENCIAS BIOLOGICAS::GENETICA
title_short A pr?tica regular do futebol: O alto rendimento deste esporte est? associado a danos gen?ticos?
title_full A pr?tica regular do futebol: O alto rendimento deste esporte est? associado a danos gen?ticos?
title_fullStr A pr?tica regular do futebol: O alto rendimento deste esporte est? associado a danos gen?ticos?
title_full_unstemmed A pr?tica regular do futebol: O alto rendimento deste esporte est? associado a danos gen?ticos?
title_sort A pr?tica regular do futebol: O alto rendimento deste esporte est? associado a danos gen?ticos?
author Motta, Marcelo Trotte
author_facet Motta, Marcelo Trotte
author_role author
dc.contributor.advisor1.fl_str_mv Cerqueira, Eneida de Moraes Marc?lio
dc.contributor.advisor1ID.fl_str_mv 04104455504
dc.contributor.authorID.fl_str_mv 41419910582
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/3989639095741797
dc.contributor.author.fl_str_mv Motta, Marcelo Trotte
contributor_str_mv Cerqueira, Eneida de Moraes Marc?lio
dc.subject.por.fl_str_mv Radicais livres
Micron?cleos
Danos ao DNA
Futebol
topic Radicais livres
Micron?cleos
Danos ao DNA
Futebol
Free radicals
Micronuclei
DNA damage
Soccer
CIENCIAS BIOLOGICAS
CIENCIAS BIOLOGICAS::GENETICA
dc.subject.eng.fl_str_mv Free radicals
Micronuclei
DNA damage
Soccer
dc.subject.cnpq.fl_str_mv CIENCIAS BIOLOGICAS
CIENCIAS BIOLOGICAS::GENETICA
description Although physical training has been encouraged as a health-promoting activity, high intensity exercises lead to increased oxidative processes taking place in the mitochondria, thus generating reactive oxygen species, known for inducing DNA damage. This study is aimed at identifying the chromosomal damage in soccer players both during the games and in their physical and technical training programs by means of the Micronucleus Test for lymphocytes following the protocol proposed by Fenech (2000). The sample consisted of three groups: Group I, comprising fifteen soccer players under an intense physical training schedule; Group II, composed of 18 subjects performing physical activities on a regular basis; and Group III with 19 sedentary subjects. The statistical analysis of the number of micronuclei found in the total amount of cells under investigation did not present any significant diferences either in the absolute number of cells with micronuclei or in their mean number: ??2=0.3603; G.L.=2; p> 0.70 and F2,,49 = 0.1185; p= 0.8887, respectively. Results in this experiment conditions do not show the potential for micronucleus analysis to biomonitor subjects under intense physical training and point out the need for further studies before this cytogenetic endpoint becomes a risk biomarker.
publishDate 2007
dc.date.issued.fl_str_mv 2007-07-31
dc.date.accessioned.fl_str_mv 2020-08-18T16:47:37Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
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dc.identifier.citation.fl_str_mv MOTTA, Marcelo Trotte. A pr?tica regular do futebol: O alto rendimento deste esporte est? associado a danos gen?ticos?. 2007. 75 f. Disserta??o (Mestrado Acad?mico em Biotecnologia)- Universidade Estadual de Feira de Santana, Feira de Santana, 2007.
dc.identifier.uri.fl_str_mv http://tede2.uefs.br:8080/handle/tede/1206
identifier_str_mv MOTTA, Marcelo Trotte. A pr?tica regular do futebol: O alto rendimento deste esporte est? associado a danos gen?ticos?. 2007. 75 f. Disserta??o (Mestrado Acad?mico em Biotecnologia)- Universidade Estadual de Feira de Santana, Feira de Santana, 2007.
url http://tede2.uefs.br:8080/handle/tede/1206
dc.language.iso.fl_str_mv por
language por
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dc.publisher.program.fl_str_mv Mestrado Acad?mico em Biotecnologia
dc.publisher.initials.fl_str_mv UEFS
dc.publisher.country.fl_str_mv Brasil
dc.publisher.department.fl_str_mv DEPARTAMENTO DE CI?NCIAS BIOL?GICAS
publisher.none.fl_str_mv Universidade Estadual de Feira de Santana
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