Distribuição espacial da coinfecção leishmaniose visceral-HIV em Teresina/PI, 2006 a 2015.

• Ano de defesa: 2018
• Autor(a) principal: Silva, Luciana da Rocha Mota da
• Orientador(a): Werneck, Guilherme Loureiro
• Banca de defesa: Braga, Jose Ueleres , Medronho, Roberto de Andrade , Almeida, Andréa Sobral de
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade do Estado do Rio de Janeiro
• Programa de Pós-Graduação: Programa de Pós-Graduação em Saúde Coletiva
• Departamento: Centro Biomédico::Instituto de Medicina Social
• País: BR
• Palavras-chave em Português: Leishmaniose visceral; HIV; Coinfecção; Sistema de Informação Geográfica
• Palavras-chave em Inglês: Visceral leishmaniasis; HIV; Coinfection; Geographic Information System
• Área do conhecimento CNPq: CNPQ::CIENCIAS DA SAUDE::SAUDE COLETIVA
• Link de acesso: http://www.bdtd.uerj.br/handle/1/3920

Each year occur approximately 50 to 90 thousand new cases of visceral leishmaniasis (VL). More than 90% of the cases of VL occur in seven countries of the world: Brazil, Ethiopia, India, Kenya, Somalia, Sudan and South Sudan. In Latin America, 96% occur in Brazil. The VL-HIV coinfection has been considered as emerging disease in several regions of the world depending on the geographical overlap of both infections as a result of leishmaniasis urbanization and HIV infection interiorization. The VL-HIV coinfection usually results in unfavorable treatment responses, frequent relapses and premature deaths. The objective of this study was to describe and analyze the clinical and epidemiologic profiles and the spatial and temporal distribution of VL-HIV coinfection in Teresina/PI, from 2006 to 2015. It is a cross-sectional study, with temporal dimension, developed from geo-referenced data for the address of residence domicile concerning notified and confirmed VL and VL-HIV cases in the Brazilian Disease Information System. From the total number of cases of LV notified within the period of the study (737), 19.4% were of VL-HIV coinfection. The proportion of VL-HIV cases coinfection in relation to LV cases was 8.6% in 2006 and 47.7% in 2015, the coefficient of incidence was 0.87 cases per 100,000 inhabitants and 2.49 cases per 100.00 inhabitants, in the same periods. Highlights the clinical and laboratory diagnosis difference between the two groups with weakness, weight loss, infection and hemorrhagic phenomena the most frequent clinical manifestations in patients with LV-HIV. The mortality and recurrence were approximately two times higher in this group, 11.4% and 13.3%, respectively. It was evidenced greater VL-HIV spatial aggregation cases in relation to that observed for LV cases. The results presented in this research contributes to the knowledge about the clinical and epidemiological diagnosis and the process of VL-HIV coinfection occurrence, potentiating prevention and health planning actions.