Efeitos do jejum noturno sobre a força muscular de pacientes internados para tratamento clínico

• Ano de defesa: 2018
• Autor(a) principal: Arruda, Wesley Santana Correa de
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de Mato Grosso; Brasil; Faculdade de Medicina (FM); UFMT CUC - Cuiabá; Programa de Pós-Graduação em Ciências da Saúde
• Palavras-chave em Português: Jejum; Capacidade funcional; Dinamometria; CNPQ::CIENCIAS DA SAUDE::MEDICINA; Fasting; Hand grip; Muscular function
• Link de acesso: http://ri.ufmt.br/handle/1/4235

Malnutrition related muscular function alterations appear before changes in anthropometric and laboratory parameters. Fasting for exams, procedures and surgeries can result in reduced functional capacity. Hand grip strength (HGS) as a method for nutritional evaluation, is simple, fast, useful, inexpensive, and efficacious test for muscular function. Objective: To investigate the effects of an overnight fasting on the handgrip strength (HGS) in hospitalized adult patients for medical treatment. Method: Prospective clinical study enrolling 221 adult patients. The endpoints were the HGS (kg) obtained by dynamometry in three time points (morning after an overnight fasting, after breakfast and after lunch) and the cumulative HGS (mean of HGS after breakfast and lunch) in the same day. The mean of three HGS measures was considered to represent each time point. A cut-off for the mean overnight fasting HGS at the 50th percentile (35.5kg for males and 27.7kg for females) was used for comparisons. We also registered the age, sex, current and usual weight (kg), weight loss (kg), diagnosis of cancer, nutritional status, elderly frequency, digestive tract symptoms, type of oral diet, and the amount of dinner ingested the night before HGS (zero intake, until 50%, ≥50-<100% and 100%). Results: HGS evaluated after an overnight fasting (31.2±8.7 kg) was lesser when compared with HGS after breakfast (31.6±8.8kg, p=0.01) and with cumulative HGS (47.3±13.0 kg; p<0.001). HGS was greater in patients who ingested 100% (33.2±9.1 vs 30.4±8.4 kg, p=0.03) and above 50% of the dinner (32.1±8 , 4 vs 28.6±8.8 kg, p=0.006). Multivariate analysis showed that ingesting below 50% of dinner, severe malnutrition, and elderly were independent factors for HGS reduction after overnight fasting. Conclusion: The muscular function determined by HGS is impaired after an overnight fasting especially in malnourished and elderly, in hospitalized adult patients for medical treatment.