SAÚDE BUCAL DE CRIANÇAS E ADOLESCENTES COM PARALISIA CEREBRAL: ASPECTOS CLÍNICOS E BIOQUÍMICOS

• Ano de defesa: 2018
• Autor(a) principal: Malta, Cristiana Pereira
• Orientador(a): Bento, Leticia Westphalen
• Banca de defesa: Barcelos, Cristine Silva, Antoniazzi, Raquel Pippi
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Franciscana
• Programa de Pós-Graduação: Mestrado em Ciências da Saúde e da Vida
• Departamento: Ciências da Saúde e da Vida
• País: Brasil
• Palavras-chave em Português: Paralisia Cerebral; Saúde bucal; Cuidador; Saliva; Estresse Oxidativo.
• Palavras-chave em Inglês: Cerebral Palsy; Oral health; Caregiver; Saliva; Oxidative stress.
• Área do conhecimento CNPq: Ciências da Saúde e da Vida
• Link de acesso: http://www.tede.universidadefranciscana.edu.br:8080/handle/UFN-BDTD/612

The aim of this study was to evaluate the clinical and biochemical aspects of the oral conditions of children and adolescents with cerebral palsy (CP), comparing this with patients with typical development, and to associate the clinical circumstances with the caregivers’ perception regarding oral health. This cross-sectional study occurred from March to September 2017. The study group consisted of 35 children and adolescents of both sexes, with clinical diagnosis of PC and age between 2 and 20 years. The control group consisted of 35 individuals with typical development, paired to the study group for age, sex and caries activity. A questionnaire was administered to caregivers with questions related to the oral health of the individuals under their care. The clinical examination included: caries activity, dmft/DMFT index, visible plaque index (VPI) and occlusal characteristics. The non-stimulated total saliva was collected through a special sterile polypropylene tube associated to the sucker of the dental equipment. Saliva was used to assess pH, buffer capacity and oxidative status. A total of 57.2% of children and adolescents with CP had experience of caries. The mean dmft/DMFT of the study group was 2.77±3.20. Regarding the perception of the caregivers, there were statistically significant differences between the groups, in the perception of problems in the teeth (p = 0.004) and gingival bleeding (p = 0.013). Class II molar relation, overjet and anterior open bite were more prevalent in children and adolescents with CP. CP was related to lower salivary pH, higher IPV, higher salivary levels of reactive species and lipid peroxidation. In addition, CP was able to modulate salivary levels of non-enzymatic antioxidants such as reduced glutathione (GSH) and vitamin C (VIT C). It can be concluded that caregivers of people with CP reported perceiving more problems in oral health, such as visible biofilm, gingival bleeding and malocclusion, than caregivers of children with typical development. In addition, CP was associated with lower salivary pH, higher IPV, higher oxidative status, and modulated the endogenous antioxidant defense system of saliva.