Secondary caries & local factors related to its development
Ano de defesa: | 2018 |
---|---|
Autor(a) principal: | |
Orientador(a): | |
Banca de defesa: | |
Tipo de documento: | Tese |
Tipo de acesso: | Acesso aberto |
Idioma: | por |
Instituição de defesa: |
Universidade Federal de Pelotas
|
Programa de Pós-Graduação: |
Programa de Pós-Graduação em Odontologia
|
Departamento: |
Faculdade de Odontologia
|
País: |
Brasil
|
Palavras-chave em Português: | |
Área do conhecimento CNPq: | |
Link de acesso: | http://guaiaca.ufpel.edu.br/handle/prefix/4672 |
Resumo: | Objectives: This in situ study aimed to investigate the influence of very small gaps in SC development and additionally to link the level of SC and a threshold gap size with the caries activity level of the volunteer. Methods: For 21 days, 15 volunteers wore a modified occlusal splint loaded with dentin-composite samples restored according to different interface conditions: bonded (B = samples restored with complete adhesive procedure), no-bonded (NB = restored with composite resin without adhesive procedure), and 30, 60 and 90 µm (no adhesive procedure and with intentional gap). Eight times per day, the splint with samples was dipped in a 20% sucrose solution for 10 minutes. Before and after caries development, samples were imaged with T-WIM and lesion depth and mineral loss were calculated. Volunteers were grouped according to the average wall lesion depth and classified as high, mid and low caries activity levels. Results: No wall lesion formation was observed in B and NB groups. In general, intentional gaps led to SC lesion depth progression independent of caries activity level of volunteers. No substantial wall lesions were found for two volunteers. A trend for deeper lesion in larger gaps was observed for the high activity group. Conclusion: Very small gaps around or wider than 30 µm develop SC independent of the caries activity level of the patient and SC wall lesion progression seemed to be related to individual factors even in this standardized in situ model. |
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http://lattes.cnpq.br/7002526052329236http://lattes.cnpq.br/9213734590954928Huymans, Marie-CharlotteKuper, NicolienCenci, Maximiliano SérgioMaske, Tamires Timm2019-08-07T15:38:52Z2019-08-07T15:38:52Z2018-07-12MASKE, Tamires Timm. Secondary caries and local factors related to its development. 2018. 170 f. Tese (Doutorado em Odontologia) - Programa de Pós-Graduação em Odontologia, Faculdade de Odontologia, Universidade Federal de Pelotas, Pelotas, 2018.http://guaiaca.ufpel.edu.br/handle/prefix/4672Objectives: This in situ study aimed to investigate the influence of very small gaps in SC development and additionally to link the level of SC and a threshold gap size with the caries activity level of the volunteer. Methods: For 21 days, 15 volunteers wore a modified occlusal splint loaded with dentin-composite samples restored according to different interface conditions: bonded (B = samples restored with complete adhesive procedure), no-bonded (NB = restored with composite resin without adhesive procedure), and 30, 60 and 90 µm (no adhesive procedure and with intentional gap). Eight times per day, the splint with samples was dipped in a 20% sucrose solution for 10 minutes. Before and after caries development, samples were imaged with T-WIM and lesion depth and mineral loss were calculated. Volunteers were grouped according to the average wall lesion depth and classified as high, mid and low caries activity levels. Results: No wall lesion formation was observed in B and NB groups. In general, intentional gaps led to SC lesion depth progression independent of caries activity level of volunteers. No substantial wall lesions were found for two volunteers. A trend for deeper lesion in larger gaps was observed for the high activity group. Conclusion: Very small gaps around or wider than 30 µm develop SC independent of the caries activity level of the patient and SC wall lesion progression seemed to be related to individual factors even in this standardized in situ model.The aim of this systematic review is to characterize and discuss key methodological aspects of in vitro biofilm models for caries-related research and to verify the reproducibility and dose-response of models considering the response to anticaries and/or antimicrobial substances. Inclusion criteria were divided into Part I (PI): an in vitro biofilm model that produces a cariogenic biofilm and/or carieslike lesions and allows pH fluctuations; and Part II (PII): models showing an effect of anti-caries and/or antimicrobial substances. Within PI, 72.9% consisted of dynamic biofilm models, while 27.1% consisted of batch models. Within PII, 75.5% corresponded to dynamic models, whereas 24.5% corresponded to batch models. Respectively, 20.4 and 14.3% of the studies reported dose-response validations and reproducibility, and 32.7% were classified as having a high risk of bias. Several in vitro biofilm models are available for caries-related research; however, most models lack validation by dose-response and reproducibility experiments for each proposed protocol.Conselho Nacional de Pesquisa e Desenvolvimento Científico e Tecnológico - CNPqporUniversidade Federal de PelotasPrograma de Pós-Graduação em OdontologiaUFPelBrasilFaculdade de OdontologiaCNPQ::CIENCIAS DA SAUDE::ODONTOLOGIASecondary cariesWall lesionBiofilmMmpSecondary caries & local factors related to its developmentinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/doctoralThesisinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFPel - Guaiacainstname:Universidade Federal de Pelotas (UFPEL)instacron:UFPELTEXTSecondary caries and local factors.pdf.txtSecondary caries and local factors.pdf.txtExtracted texttext/plain302922http://guaiaca.ufpel.edu.br/xmlui/bitstream/prefix/4672/6/Secondary%20caries%20and%20local%20factors.pdf.txt663b705af0fda400af1030a980bab770MD56open accessTHUMBNAILSecondary caries and local factors.pdf.jpgSecondary caries and local factors.pdf.jpgGenerated Thumbnailimage/jpeg1128http://guaiaca.ufpel.edu.br/xmlui/bitstream/prefix/4672/7/Secondary%20caries%20and%20local%20factors.pdf.jpgccc338ff7976c4f2828c5fcab0ba52feMD57open accessORIGINALSecondary caries and local factors.pdfSecondary caries and local factors.pdfapplication/pdf4471079http://guaiaca.ufpel.edu.br/xmlui/bitstream/prefix/4672/1/Secondary%20caries%20and%20local%20factors.pdfa154abf13653063cf9314c98425aa49eMD51open accessCC-LICENSElicense_urllicense_urltext/plain; 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dc.title.pt_BR.fl_str_mv |
Secondary caries & local factors related to its development |
title |
Secondary caries & local factors related to its development |
spellingShingle |
Secondary caries & local factors related to its development Maske, Tamires Timm CNPQ::CIENCIAS DA SAUDE::ODONTOLOGIA Secondary caries Wall lesion Biofilm Mmp |
title_short |
Secondary caries & local factors related to its development |
title_full |
Secondary caries & local factors related to its development |
title_fullStr |
Secondary caries & local factors related to its development |
title_full_unstemmed |
Secondary caries & local factors related to its development |
title_sort |
Secondary caries & local factors related to its development |
author |
Maske, Tamires Timm |
author_facet |
Maske, Tamires Timm |
author_role |
author |
dc.contributor.authorLattes.pt_BR.fl_str_mv |
http://lattes.cnpq.br/7002526052329236 |
dc.contributor.advisorLattes.pt_BR.fl_str_mv |
http://lattes.cnpq.br/9213734590954928 |
dc.contributor.advisor-co1.fl_str_mv |
Huymans, Marie-Charlotte |
dc.contributor.advisor-co2.fl_str_mv |
Kuper, Nicolien |
dc.contributor.advisor1.fl_str_mv |
Cenci, Maximiliano Sérgio |
dc.contributor.author.fl_str_mv |
Maske, Tamires Timm |
contributor_str_mv |
Huymans, Marie-Charlotte Kuper, Nicolien Cenci, Maximiliano Sérgio |
dc.subject.cnpq.fl_str_mv |
CNPQ::CIENCIAS DA SAUDE::ODONTOLOGIA |
topic |
CNPQ::CIENCIAS DA SAUDE::ODONTOLOGIA Secondary caries Wall lesion Biofilm Mmp |
dc.subject.por.fl_str_mv |
Secondary caries Wall lesion Biofilm Mmp |
description |
Objectives: This in situ study aimed to investigate the influence of very small gaps in SC development and additionally to link the level of SC and a threshold gap size with the caries activity level of the volunteer. Methods: For 21 days, 15 volunteers wore a modified occlusal splint loaded with dentin-composite samples restored according to different interface conditions: bonded (B = samples restored with complete adhesive procedure), no-bonded (NB = restored with composite resin without adhesive procedure), and 30, 60 and 90 µm (no adhesive procedure and with intentional gap). Eight times per day, the splint with samples was dipped in a 20% sucrose solution for 10 minutes. Before and after caries development, samples were imaged with T-WIM and lesion depth and mineral loss were calculated. Volunteers were grouped according to the average wall lesion depth and classified as high, mid and low caries activity levels. Results: No wall lesion formation was observed in B and NB groups. In general, intentional gaps led to SC lesion depth progression independent of caries activity level of volunteers. No substantial wall lesions were found for two volunteers. A trend for deeper lesion in larger gaps was observed for the high activity group. Conclusion: Very small gaps around or wider than 30 µm develop SC independent of the caries activity level of the patient and SC wall lesion progression seemed to be related to individual factors even in this standardized in situ model. |
publishDate |
2018 |
dc.date.issued.fl_str_mv |
2018-07-12 |
dc.date.accessioned.fl_str_mv |
2019-08-07T15:38:52Z |
dc.date.available.fl_str_mv |
2019-08-07T15:38:52Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/doctoralThesis |
format |
doctoralThesis |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
MASKE, Tamires Timm. Secondary caries and local factors related to its development. 2018. 170 f. Tese (Doutorado em Odontologia) - Programa de Pós-Graduação em Odontologia, Faculdade de Odontologia, Universidade Federal de Pelotas, Pelotas, 2018. |
dc.identifier.uri.fl_str_mv |
http://guaiaca.ufpel.edu.br/handle/prefix/4672 |
identifier_str_mv |
MASKE, Tamires Timm. Secondary caries and local factors related to its development. 2018. 170 f. Tese (Doutorado em Odontologia) - Programa de Pós-Graduação em Odontologia, Faculdade de Odontologia, Universidade Federal de Pelotas, Pelotas, 2018. |
url |
http://guaiaca.ufpel.edu.br/handle/prefix/4672 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
Universidade Federal de Pelotas |
dc.publisher.program.fl_str_mv |
Programa de Pós-Graduação em Odontologia |
dc.publisher.initials.fl_str_mv |
UFPel |
dc.publisher.country.fl_str_mv |
Brasil |
dc.publisher.department.fl_str_mv |
Faculdade de Odontologia |
publisher.none.fl_str_mv |
Universidade Federal de Pelotas |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UFPel - Guaiaca instname:Universidade Federal de Pelotas (UFPEL) instacron:UFPEL |
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Universidade Federal de Pelotas (UFPEL) |
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UFPEL |
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UFPEL |
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Repositório Institucional da UFPel - Guaiaca |
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