Secondary caries & local factors related to its development

Detalhes bibliográficos
Ano de defesa: 2018
Autor(a) principal: Maske, Tamires Timm
Orientador(a): Cenci, Maximiliano Sérgio
Banca de defesa: Não Informado pela instituição
Tipo de documento: Tese
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Federal de Pelotas
Programa de Pós-Graduação: Programa de Pós-Graduação em Odontologia
Departamento: Faculdade de Odontologia
País: Brasil
Palavras-chave em Português:
Mmp
Área do conhecimento CNPq:
Link de acesso: http://guaiaca.ufpel.edu.br/handle/prefix/4672
Resumo: Objectives: This in situ study aimed to investigate the influence of very small gaps in SC development and additionally to link the level of SC and a threshold gap size with the caries activity level of the volunteer. Methods: For 21 days, 15 volunteers wore a modified occlusal splint loaded with dentin-composite samples restored according to different interface conditions: bonded (B = samples restored with complete adhesive procedure), no-bonded (NB = restored with composite resin without adhesive procedure), and 30, 60 and 90 µm (no adhesive procedure and with intentional gap). Eight times per day, the splint with samples was dipped in a 20% sucrose solution for 10 minutes. Before and after caries development, samples were imaged with T-WIM and lesion depth and mineral loss were calculated. Volunteers were grouped according to the average wall lesion depth and classified as high, mid and low caries activity levels. Results: No wall lesion formation was observed in B and NB groups. In general, intentional gaps led to SC lesion depth progression independent of caries activity level of volunteers. No substantial wall lesions were found for two volunteers. A trend for deeper lesion in larger gaps was observed for the high activity group. Conclusion: Very small gaps around or wider than 30 µm develop SC independent of the caries activity level of the patient and SC wall lesion progression seemed to be related to individual factors even in this standardized in situ model.
id UFPL_211dc323de4fd1d61387b9d4bfe9605e
oai_identifier_str oai:guaiaca.ufpel.edu.br:prefix/4672
network_acronym_str UFPL
network_name_str Repositório Institucional da UFPel - Guaiaca
repository_id_str
spelling http://lattes.cnpq.br/7002526052329236http://lattes.cnpq.br/9213734590954928Huymans, Marie-CharlotteKuper, NicolienCenci, Maximiliano SérgioMaske, Tamires Timm2019-08-07T15:38:52Z2019-08-07T15:38:52Z2018-07-12MASKE, Tamires Timm. Secondary caries and local factors related to its development. 2018. 170 f. Tese (Doutorado em Odontologia) - Programa de Pós-Graduação em Odontologia, Faculdade de Odontologia, Universidade Federal de Pelotas, Pelotas, 2018.http://guaiaca.ufpel.edu.br/handle/prefix/4672Objectives: This in situ study aimed to investigate the influence of very small gaps in SC development and additionally to link the level of SC and a threshold gap size with the caries activity level of the volunteer. Methods: For 21 days, 15 volunteers wore a modified occlusal splint loaded with dentin-composite samples restored according to different interface conditions: bonded (B = samples restored with complete adhesive procedure), no-bonded (NB = restored with composite resin without adhesive procedure), and 30, 60 and 90 µm (no adhesive procedure and with intentional gap). Eight times per day, the splint with samples was dipped in a 20% sucrose solution for 10 minutes. Before and after caries development, samples were imaged with T-WIM and lesion depth and mineral loss were calculated. Volunteers were grouped according to the average wall lesion depth and classified as high, mid and low caries activity levels. Results: No wall lesion formation was observed in B and NB groups. In general, intentional gaps led to SC lesion depth progression independent of caries activity level of volunteers. No substantial wall lesions were found for two volunteers. A trend for deeper lesion in larger gaps was observed for the high activity group. Conclusion: Very small gaps around or wider than 30 µm develop SC independent of the caries activity level of the patient and SC wall lesion progression seemed to be related to individual factors even in this standardized in situ model.The aim of this systematic review is to characterize and discuss key methodological aspects of in vitro biofilm models for caries-related research and to verify the reproducibility and dose-response of models considering the response to anticaries and/or antimicrobial substances. Inclusion criteria were divided into Part I (PI): an in vitro biofilm model that produces a cariogenic biofilm and/or carieslike lesions and allows pH fluctuations; and Part II (PII): models showing an effect of anti-caries and/or antimicrobial substances. Within PI, 72.9% consisted of dynamic biofilm models, while 27.1% consisted of batch models. Within PII, 75.5% corresponded to dynamic models, whereas 24.5% corresponded to batch models. Respectively, 20.4 and 14.3% of the studies reported dose-response validations and reproducibility, and 32.7% were classified as having a high risk of bias. Several in vitro biofilm models are available for caries-related research; however, most models lack validation by dose-response and reproducibility experiments for each proposed protocol.Conselho Nacional de Pesquisa e Desenvolvimento Científico e Tecnológico - CNPqporUniversidade Federal de PelotasPrograma de Pós-Graduação em OdontologiaUFPelBrasilFaculdade de OdontologiaCNPQ::CIENCIAS DA SAUDE::ODONTOLOGIASecondary cariesWall lesionBiofilmMmpSecondary caries & local factors related to its developmentinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/doctoralThesisinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFPel - Guaiacainstname:Universidade Federal de Pelotas (UFPEL)instacron:UFPELTEXTSecondary caries and local factors.pdf.txtSecondary caries and local factors.pdf.txtExtracted texttext/plain302922http://guaiaca.ufpel.edu.br/xmlui/bitstream/prefix/4672/6/Secondary%20caries%20and%20local%20factors.pdf.txt663b705af0fda400af1030a980bab770MD56open accessTHUMBNAILSecondary caries and local factors.pdf.jpgSecondary caries and local factors.pdf.jpgGenerated Thumbnailimage/jpeg1128http://guaiaca.ufpel.edu.br/xmlui/bitstream/prefix/4672/7/Secondary%20caries%20and%20local%20factors.pdf.jpgccc338ff7976c4f2828c5fcab0ba52feMD57open accessORIGINALSecondary caries and local factors.pdfSecondary caries and local factors.pdfapplication/pdf4471079http://guaiaca.ufpel.edu.br/xmlui/bitstream/prefix/4672/1/Secondary%20caries%20and%20local%20factors.pdfa154abf13653063cf9314c98425aa49eMD51open accessCC-LICENSElicense_urllicense_urltext/plain; charset=utf-843http://guaiaca.ufpel.edu.br/xmlui/bitstream/prefix/4672/2/license_url321f3992dd3875151d8801b773ab32edMD52open accesslicense_textlicense_texttext/html; charset=utf-80http://guaiaca.ufpel.edu.br/xmlui/bitstream/prefix/4672/3/license_textd41d8cd98f00b204e9800998ecf8427eMD53open accesslicense_rdflicense_rdfapplication/rdf+xml; charset=utf-80http://guaiaca.ufpel.edu.br/xmlui/bitstream/prefix/4672/4/license_rdfd41d8cd98f00b204e9800998ecf8427eMD54open accessLICENSElicense.txtlicense.txttext/plain; charset=utf-81866http://guaiaca.ufpel.edu.br/xmlui/bitstream/prefix/4672/5/license.txt43cd690d6a359e86c1fe3d5b7cba0c9bMD55open accessprefix/46722023-07-13 03:24:48.524open accessoai:guaiaca.ufpel.edu.br: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ório InstitucionalPUBhttp://repositorio.ufpel.edu.br/oai/requestrippel@ufpel.edu.br || repositorio@ufpel.edu.br || aline.batista@ufpel.edu.bropendoar:2023-07-13T06:24:48Repositório Institucional da UFPel - Guaiaca - Universidade Federal de Pelotas (UFPEL)false
dc.title.pt_BR.fl_str_mv Secondary caries & local factors related to its development
title Secondary caries & local factors related to its development
spellingShingle Secondary caries & local factors related to its development
Maske, Tamires Timm
CNPQ::CIENCIAS DA SAUDE::ODONTOLOGIA
Secondary caries
Wall lesion
Biofilm
Mmp
title_short Secondary caries & local factors related to its development
title_full Secondary caries & local factors related to its development
title_fullStr Secondary caries & local factors related to its development
title_full_unstemmed Secondary caries & local factors related to its development
title_sort Secondary caries & local factors related to its development
author Maske, Tamires Timm
author_facet Maske, Tamires Timm
author_role author
dc.contributor.authorLattes.pt_BR.fl_str_mv http://lattes.cnpq.br/7002526052329236
dc.contributor.advisorLattes.pt_BR.fl_str_mv http://lattes.cnpq.br/9213734590954928
dc.contributor.advisor-co1.fl_str_mv Huymans, Marie-Charlotte
dc.contributor.advisor-co2.fl_str_mv Kuper, Nicolien
dc.contributor.advisor1.fl_str_mv Cenci, Maximiliano Sérgio
dc.contributor.author.fl_str_mv Maske, Tamires Timm
contributor_str_mv Huymans, Marie-Charlotte
Kuper, Nicolien
Cenci, Maximiliano Sérgio
dc.subject.cnpq.fl_str_mv CNPQ::CIENCIAS DA SAUDE::ODONTOLOGIA
topic CNPQ::CIENCIAS DA SAUDE::ODONTOLOGIA
Secondary caries
Wall lesion
Biofilm
Mmp
dc.subject.por.fl_str_mv Secondary caries
Wall lesion
Biofilm
Mmp
description Objectives: This in situ study aimed to investigate the influence of very small gaps in SC development and additionally to link the level of SC and a threshold gap size with the caries activity level of the volunteer. Methods: For 21 days, 15 volunteers wore a modified occlusal splint loaded with dentin-composite samples restored according to different interface conditions: bonded (B = samples restored with complete adhesive procedure), no-bonded (NB = restored with composite resin without adhesive procedure), and 30, 60 and 90 µm (no adhesive procedure and with intentional gap). Eight times per day, the splint with samples was dipped in a 20% sucrose solution for 10 minutes. Before and after caries development, samples were imaged with T-WIM and lesion depth and mineral loss were calculated. Volunteers were grouped according to the average wall lesion depth and classified as high, mid and low caries activity levels. Results: No wall lesion formation was observed in B and NB groups. In general, intentional gaps led to SC lesion depth progression independent of caries activity level of volunteers. No substantial wall lesions were found for two volunteers. A trend for deeper lesion in larger gaps was observed for the high activity group. Conclusion: Very small gaps around or wider than 30 µm develop SC independent of the caries activity level of the patient and SC wall lesion progression seemed to be related to individual factors even in this standardized in situ model.
publishDate 2018
dc.date.issued.fl_str_mv 2018-07-12
dc.date.accessioned.fl_str_mv 2019-08-07T15:38:52Z
dc.date.available.fl_str_mv 2019-08-07T15:38:52Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/doctoralThesis
format doctoralThesis
status_str publishedVersion
dc.identifier.citation.fl_str_mv MASKE, Tamires Timm. Secondary caries and local factors related to its development. 2018. 170 f. Tese (Doutorado em Odontologia) - Programa de Pós-Graduação em Odontologia, Faculdade de Odontologia, Universidade Federal de Pelotas, Pelotas, 2018.
dc.identifier.uri.fl_str_mv http://guaiaca.ufpel.edu.br/handle/prefix/4672
identifier_str_mv MASKE, Tamires Timm. Secondary caries and local factors related to its development. 2018. 170 f. Tese (Doutorado em Odontologia) - Programa de Pós-Graduação em Odontologia, Faculdade de Odontologia, Universidade Federal de Pelotas, Pelotas, 2018.
url http://guaiaca.ufpel.edu.br/handle/prefix/4672
dc.language.iso.fl_str_mv por
language por
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Universidade Federal de Pelotas
dc.publisher.program.fl_str_mv Programa de Pós-Graduação em Odontologia
dc.publisher.initials.fl_str_mv UFPel
dc.publisher.country.fl_str_mv Brasil
dc.publisher.department.fl_str_mv Faculdade de Odontologia
publisher.none.fl_str_mv Universidade Federal de Pelotas
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFPel - Guaiaca
instname:Universidade Federal de Pelotas (UFPEL)
instacron:UFPEL
instname_str Universidade Federal de Pelotas (UFPEL)
instacron_str UFPEL
institution UFPEL
reponame_str Repositório Institucional da UFPel - Guaiaca
collection Repositório Institucional da UFPel - Guaiaca
bitstream.url.fl_str_mv http://guaiaca.ufpel.edu.br/xmlui/bitstream/prefix/4672/6/Secondary%20caries%20and%20local%20factors.pdf.txt
http://guaiaca.ufpel.edu.br/xmlui/bitstream/prefix/4672/7/Secondary%20caries%20and%20local%20factors.pdf.jpg
http://guaiaca.ufpel.edu.br/xmlui/bitstream/prefix/4672/1/Secondary%20caries%20and%20local%20factors.pdf
http://guaiaca.ufpel.edu.br/xmlui/bitstream/prefix/4672/2/license_url
http://guaiaca.ufpel.edu.br/xmlui/bitstream/prefix/4672/3/license_text
http://guaiaca.ufpel.edu.br/xmlui/bitstream/prefix/4672/4/license_rdf
http://guaiaca.ufpel.edu.br/xmlui/bitstream/prefix/4672/5/license.txt
bitstream.checksum.fl_str_mv 663b705af0fda400af1030a980bab770
ccc338ff7976c4f2828c5fcab0ba52fe
a154abf13653063cf9314c98425aa49e
321f3992dd3875151d8801b773ab32ed
d41d8cd98f00b204e9800998ecf8427e
d41d8cd98f00b204e9800998ecf8427e
43cd690d6a359e86c1fe3d5b7cba0c9b
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
MD5
MD5
MD5
MD5
repository.name.fl_str_mv Repositório Institucional da UFPel - Guaiaca - Universidade Federal de Pelotas (UFPEL)
repository.mail.fl_str_mv rippel@ufpel.edu.br || repositorio@ufpel.edu.br || aline.batista@ufpel.edu.br
_version_ 1797769988221698048