Surtos de Enteropatia Proliferativa determinados por Lawsonia intracellularis em su?nos e coelhos no Estado do Rio de Janeiro

Detalhes bibliográficos
Ano de defesa: 2007
Autor(a) principal: Ribeiro, Carlos Torres lattes
Orientador(a): Peixoto, Paulo Fernando de Vargas lattes
Banca de defesa: Brito, Marilene Farias, Dobereiner, Jurgen, Torkania, Carlos Hubinger, Pitombo, C?cero Ara?jo
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Federal Rural do Rio de Janeiro
Programa de Pós-Graduação: Programa de P?s-Gradua??o em Ci?ncias Veterin?rias
Departamento: Instituto de Veterin?ria
País: Brasil
Palavras-chave em Português:
Lawsonia intracellularis
enteropatia proliferativa
coelhos
su?nos
Palavras-chave em Inglês:
Lawsonia intracellularis
intestinal adenomatosis
pigs
rabbits
Área do conhecimento CNPq:
Medicina Veterin?ria
Link de acesso: https://tede.ufrrj.br/jspui/handle/jspui/2192
Resumo: Outbreaks of infection by Lawsonia intracelullaris in swine and rabbits in the State of Rio de Janeiro are described. The symptomathology was characterized by bloody and aquous diarrhea, with respectively superacute and acute course. Post-mortem findings were a reticulate aspect of the ileum. In swine its mucosa was moderately thickened and it contained large amounts of partially coagulated blood; in rabbits the wall of the ileum was much thickened and the contents were aquous. Histopathological examination revealed severe hyperplastic proliferation of the epithelial cells of the Lieberk?hn crypts, sometimes associated with inflammatory and necrotic alterations. Silver impregnation and imunohistochemistry demonstrated the presence of large amounts of bacteria in the cytoplasm of the cryptal epithelial cells. In swine L. intracellularis was seen also by ultramicroscopic examination. This is the first report of the disease in the State of Rio de Janeiro.
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spelling Peixoto, Paulo Fernando de Vargashttp://lattes.cnpq.br/3002512195318611Fran?a, Ticiana do NascimentoBrito, Marilene FariasDobereiner, JurgenTorkania, Carlos HubingerPitombo, C?cero Ara?johttp://lattes.cnpq.br/1339469078943200Ribeiro, Carlos Torres2018-02-07T14:43:58Z2007-08-31RIBEIRO, Carlos Torres. Surtos de Enteropatia Proliferativa determinados por Lawsonia intracellularis em su?nos e coelhos no Estado do Rio de Janeiro. 2007. 87 f. Disserta??o (Mestrado em Ci?ncias Veterin?rias) - Universidade Federal Rural do Rio de Janeiro, Serop?dica, RJ, 2007.https://tede.ufrrj.br/jspui/handle/jspui/2192Outbreaks of infection by Lawsonia intracelullaris in swine and rabbits in the State of Rio de Janeiro are described. The symptomathology was characterized by bloody and aquous diarrhea, with respectively superacute and acute course. Post-mortem findings were a reticulate aspect of the ileum. In swine its mucosa was moderately thickened and it contained large amounts of partially coagulated blood; in rabbits the wall of the ileum was much thickened and the contents were aquous. Histopathological examination revealed severe hyperplastic proliferation of the epithelial cells of the Lieberk?hn crypts, sometimes associated with inflammatory and necrotic alterations. Silver impregnation and imunohistochemistry demonstrated the presence of large amounts of bacteria in the cytoplasm of the cryptal epithelial cells. In swine L. intracellularis was seen also by ultramicroscopic examination. This is the first report of the disease in the State of Rio de Janeiro.Descrevem-se surtos de infec??o por Lawsonia intracellularis em su?nos e coelhos, ocorridos no Estado do Rio de Janeiro. A sintomatologia caracterizou-se por diarr?ia sanguinolenta e aquosa, com evolu??o superaguda e aguda, respectivamente. ? necropsia verificaram-se ?leo de aspecto reticulado, com mucosa moderadamente espessada, contendo grande quantidade de sangue parcialmente coagulado, no caso dos su?nos, e ?leo com parede muito espessada e conte?do aquoso nos coelhos. O exame histol?gico revelou marcada prolifera??o hiperpl?sica das c?lulas epiteliais das criptas de Lieberk?hn, por vezes, associada a altera??es inflamat?rias e necr?ticas. Impregna??o pela prata e t?cnica imunoistoqu?mica demonstraram presen?a da bact?ria, em grande quantidade, dentro do citoplasma das c?lulas epiteliais das criptas de su?nos e coelhos. Em su?nos, L. intracellularis tamb?m foi visualizada pela ultramicroscopia. Essa ? a primeira descri??o da enfermidade no Estado do Rio de Janeiro.Submitted by Sandra Pereira (srpereira@ufrrj.br) on 2018-02-07T14:43:58Z No. of bitstreams: 1 2007 - Carlos Torres Ribeiro.pdf: 5710755 bytes, checksum: 9715a44d07b4fa0d4b48d83f3dac6d34 (MD5)Made available in DSpace on 2018-02-07T14:43:58Z (GMT). No. of bitstreams: 1 2007 - Carlos Torres Ribeiro.pdf: 5710755 bytes, checksum: 9715a44d07b4fa0d4b48d83f3dac6d34 (MD5) Previous issue date: 2007-08-31CAPES - Coordena??o de Aperfei?oamento de Pessoal de N?vel Superiorapplication/pdfhttps://tede.ufrrj.br/retrieve/53752/2007%20-%20Carlos%20Torres%20Ribeiro.pdf.jpgporUniversidade Federal Rural do Rio de JaneiroPrograma de P?s-Gradua??o em Ci?ncias Veterin?riasUFRRJBrasilInstituto de Veterin?riaALEXOPOULOS, C.; TASSIS, P.D.; KYRIAKIS, C.S.; TZIKA, E.D.; PAPATSIROS, V.; KYRIAKIS, S.C. 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dc.title.por.fl_str_mv Surtos de Enteropatia Proliferativa determinados por Lawsonia intracellularis em su?nos e coelhos no Estado do Rio de Janeiro
dc.title.alternative.eng.fl_str_mv Outbreaks of Proliferative Enteropathy due to Lawsonia intracellularis infection in pigs and rabbits in Rio de Janeiro State
title Surtos de Enteropatia Proliferativa determinados por Lawsonia intracellularis em su?nos e coelhos no Estado do Rio de Janeiro
spellingShingle Surtos de Enteropatia Proliferativa determinados por Lawsonia intracellularis em su?nos e coelhos no Estado do Rio de Janeiro
Ribeiro, Carlos Torres
Lawsonia intracellularis
intestinal adenomatosis
pigs
rabbits
Lawsonia intracellularis
enteropatia proliferativa
coelhos
su?nos
Medicina Veterin?ria
title_short Surtos de Enteropatia Proliferativa determinados por Lawsonia intracellularis em su?nos e coelhos no Estado do Rio de Janeiro
title_full Surtos de Enteropatia Proliferativa determinados por Lawsonia intracellularis em su?nos e coelhos no Estado do Rio de Janeiro
title_fullStr Surtos de Enteropatia Proliferativa determinados por Lawsonia intracellularis em su?nos e coelhos no Estado do Rio de Janeiro
title_full_unstemmed Surtos de Enteropatia Proliferativa determinados por Lawsonia intracellularis em su?nos e coelhos no Estado do Rio de Janeiro
title_sort Surtos de Enteropatia Proliferativa determinados por Lawsonia intracellularis em su?nos e coelhos no Estado do Rio de Janeiro
author Ribeiro, Carlos Torres
author_facet Ribeiro, Carlos Torres
author_role author
dc.contributor.advisor1.fl_str_mv Peixoto, Paulo Fernando de Vargas
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/3002512195318611
dc.contributor.advisor-co1.fl_str_mv Fran?a, Ticiana do Nascimento
dc.contributor.referee1.fl_str_mv Brito, Marilene Farias
dc.contributor.referee2.fl_str_mv Dobereiner, Jurgen
dc.contributor.referee3.fl_str_mv Torkania, Carlos Hubinger
dc.contributor.referee4.fl_str_mv Pitombo, C?cero Ara?jo
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/1339469078943200
dc.contributor.author.fl_str_mv Ribeiro, Carlos Torres
contributor_str_mv Peixoto, Paulo Fernando de Vargas
Fran?a, Ticiana do Nascimento
Brito, Marilene Farias
Dobereiner, Jurgen
Torkania, Carlos Hubinger
Pitombo, C?cero Ara?jo
dc.subject.eng.fl_str_mv Lawsonia intracellularis
intestinal adenomatosis
pigs
rabbits
topic Lawsonia intracellularis
intestinal adenomatosis
pigs
rabbits
Lawsonia intracellularis
enteropatia proliferativa
coelhos
su?nos
Medicina Veterin?ria
dc.subject.por.fl_str_mv Lawsonia intracellularis
enteropatia proliferativa
coelhos
su?nos
dc.subject.cnpq.fl_str_mv Medicina Veterin?ria
description Outbreaks of infection by Lawsonia intracelullaris in swine and rabbits in the State of Rio de Janeiro are described. The symptomathology was characterized by bloody and aquous diarrhea, with respectively superacute and acute course. Post-mortem findings were a reticulate aspect of the ileum. In swine its mucosa was moderately thickened and it contained large amounts of partially coagulated blood; in rabbits the wall of the ileum was much thickened and the contents were aquous. Histopathological examination revealed severe hyperplastic proliferation of the epithelial cells of the Lieberk?hn crypts, sometimes associated with inflammatory and necrotic alterations. Silver impregnation and imunohistochemistry demonstrated the presence of large amounts of bacteria in the cytoplasm of the cryptal epithelial cells. In swine L. intracellularis was seen also by ultramicroscopic examination. This is the first report of the disease in the State of Rio de Janeiro.
publishDate 2007
dc.date.issued.fl_str_mv 2007-08-31
dc.date.accessioned.fl_str_mv 2018-02-07T14:43:58Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.citation.fl_str_mv RIBEIRO, Carlos Torres. Surtos de Enteropatia Proliferativa determinados por Lawsonia intracellularis em su?nos e coelhos no Estado do Rio de Janeiro. 2007. 87 f. Disserta??o (Mestrado em Ci?ncias Veterin?rias) - Universidade Federal Rural do Rio de Janeiro, Serop?dica, RJ, 2007.
dc.identifier.uri.fl_str_mv https://tede.ufrrj.br/jspui/handle/jspui/2192
identifier_str_mv RIBEIRO, Carlos Torres. Surtos de Enteropatia Proliferativa determinados por Lawsonia intracellularis em su?nos e coelhos no Estado do Rio de Janeiro. 2007. 87 f. Disserta??o (Mestrado em Ci?ncias Veterin?rias) - Universidade Federal Rural do Rio de Janeiro, Serop?dica, RJ, 2007.
url https://tede.ufrrj.br/jspui/handle/jspui/2192
dc.language.iso.fl_str_mv por
language por
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Proliferative Haemorrhagica enteropathy in pigs, Veterinary Record, London, v. 100, n. 4, p. 65-8, 1977 MacINTYRE, N.; SMITH, D.G.E.; SHAW, D.J.; THOMSON, J.R.; RHIND, S.M. Immunopathogenesis of experimentally induced Proliferative Enteropathy in pigs Veterinary Pathology, v. 40, p. 421-432, 2003 MAPOTHER, M.E.; JOENS, L.A.; GLOCK, R.D. Experimental reproduction of porcine proliferative enteritis, Veterinary Record, v. 121, p. 533-536, 1987 84 MAUCH, C.P.; BILKEI, G., Reproductive performance of gilts following na outbreak of acute proliferative enteropathy due to Lawsonia intracellularis, Veterinary Journal, v. 170, p. 128-31, 2005 McCLUSKEY; J.; HANNIGAN; J.; HARRIS, J.D.; WREN, B.; SMITH, D.G.E. LsaA, an antigen involved in cell attachment and invasion, is expressed by Lawsonia intracellularis during infection in vitro and in vivo, Infection and Immunity, v. 70, n. 6, p. 2899-2907, 2002 McORIST, S. Defining the full costs of endemic porcine proliferative enteropathy, The Veterinary Journal, v. 170, p. 8-9, 2005 McORIST, S.; BOID, R.; LAWSON, G.H.K. Antigenic analysis of Campylobacter species and an intracellular Campylobacter-like organism associated with Porcine Proliferative Enteropathies, Infection and Immunity, v.57, n. 3, p. 957-962, 1989 McORIST, S.; MacINTYRE, N.; STOKES, C.R.; LAWSON, G.H.K. Immunocytological responses in porcine proliferative enteropathies, Infection and Immunity, v. 60, p. 4184- 4191, 1992 McORIST, S.; GEBHART; C.J.; BOID, R.; BARNS, S.M. Characterization of lawsoniaintracellularis gen-nov, sp-nov, the obligately intracellular bacterium of porcine proliferative enteropathy, International Journal of Systematic Bacteriology, v. 45, n.4, p. 820-825, 1995 McORIST, S.; JASNI, S.; MACKIE, R.; MacINTYRE, N.; NEEF, N.; LAWSON, G. Reproduction of porcine proliferative enteropathy with pure cultures of ileal symbiont intracellularis, Infection and Immunology, v. 61, n. 10, p. 4286-4292, 1993 McORIST, S., SMITH, S.H., GREEN, L.E. Estimate of Direct financial losses due to porcine proliferative enteropathy, Veterinary Record, v. 140, p. 579-581, 1997 MOON, H.W.; CUTLIP, R.C.; AMTOWER, W.C.; MATTHEWS, P.J. Intraepitelial Vibrio associated with acute typhlitis of young rabbits, Veterinary Pathology, v. 11, p. 313-326, 1974 MORENO, A.M. Enterite Proliferativa Su?na: Aspectos cl?nico-patol?gicos e epidemiol?gicos, 1v., 55p., Universidade de S?o Paulo, Patologia Experimental e Comparada, Tese defendida em 01/11/1999 85 MOR?S, N.; NEVES, D.S.; NOGUEIRA, R.H.G.; GUIMAR?ES, E.B. Diagn?sticos cl?nico e An?tomo-Histol?gicos de Casos espont?neos de Enteropatia Proliferante e Hemorr?gica (EPH) em su?nos, Arquivo Brasileiro de Medicina Veterin?ria e Zootecnia, v. 37, n.1, p. 29-37, 1985 PEARCE, G.P. Interactions between dietary fibre, endo -parasites and Lawsonia intracellularis bacteria in grower-finisher pigs, Veterinary Parasitology, v. 87, p. 51-61, 1997 PLAWINSKA, J.; BINEK, M. Lawsonia intracellularis ? The causative agent of Porcine Proliferative Enteritis, Medycyna Weterynaryjna, v. 62, n. 8, p. 860-864, 2006 ROBERTS, L.; ROWLAND, A.C.; LAWSON, G.H.K. Experimental reproduction of porcine intestinal adenomatosis and necrotic enteritis, Veterinary Record, v. 100, p. 12-13, 1977 RODR?GUEZ, J.C.; ALVAREZ, M.; RODR?GUEZ, L.; SEGURA, J.C. A longitudinal study of porcine proliferative enteropathy in a commercial pig farm in Yucatan Mexico, Arquivo Brasileiro de Medicina Veterin?ria e Zootecnia, v. 57, n. 3, p. 401-404, 2005 ROWLAND, A.C.; HUTCHINGS, D.A. Necrotic enteritis and regional ileitis in pigs at slaughter, Veterinary Record, London, v. 103, n. 15, p. 338-339, 1978 ROWLAND, A.C.; LAWSON, G.H.K. Porcine intestinal adenomatosis: a possible relationship with necrotic enteritis, regional ileitis and proliferative haemorrhagic enteropathy, Veterinary Record, London, v. 97, n. 10, p. 178-180, 1975 ROWLAND, A.C.; LAWSON, G.H.K. Porcine proliferative enterophaties, In: LEMAN, A.D.; STRAW, B.E.; MENGELING, W.L.; D?ALLAIRE, S.; TAYLOR, D.J. (Eds.), Diseases of Swine , 7a Edi??o, Iowa State University Press, Iwoa, pp. 560-569, 1992 ROWLAND, A.C.; ROWNTREE, P.G.M. Haemorrhagic Bowel Syndrome associated with intestinal adenomatosis in the pig, Veterinary Record, v. 91, p. 235-241, 1972 RUEMMELE, F.C.; GURBINDO, C.; MANSOUR, A.M.; MARCHAND. R.; LEVY, E.; SEIDMAN, E.G. Effects of interferon gamma on growth, apoptosis, and MHC class II expression of immature rat intestinal crypt (IEC-6) cells, Journal Cell Physiology, v.176, n. 1, p. 120-126, 1998 apud SMITH, D.G.E.; MITCHELL, S.C.; NASH, T.; RHIND, S. Gamma interferon influences intestinal epithelial hype rplasma caused by Lawsonia intracellularis infection in mice, Infection and Immunology, v. 68, p. 6737-6743, 2000 86 SCHAUER, D.B., MCCATHEY, S.N., DAFT, B.M. et al. Proliferative Enterocolitis associated with dual infection with Enteropathogenic Escherichia coli and Lawsonia intracellularis in rabbits, Journal of Clinical Microbiology, v. 36, n. 6, p. 1700-1703, 1998 SEGAL?S, J; FERN?NDEZ-SALGUERO, J.M.; FRUCTUOSO, G.; QUINTANA, J.;. ROSELL, J. POZO, J.; ARRIBA, M.L; RUBIO, M.; DOMINGO, J. Granulomatous Enteritis and Lymphadenitis in Iberian Pigs Naturally Infected with Lawsonia intracellularis Veterinary Pathology, v. 38, n. 3, p. 343?346, 2001 SMITH, D.G.E.; MITCHELL, S.C.; NASH, T.; RHIND, S. Gamma interferon influences intestinal epithelial hyperplasma caused by Lawsonia intracellularis infection in mice, Infection and Immunology, v. 68, p. 6737-6743, 2000 SMITH D.G.E, LAWSON GH. 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Detection of lawsonia intracelularis in diagnostic specimens by one -step PCR, Journal of Veterinary Science, v. 1, n. 1, p. 33-37, 2000 SUH, D.K.; SONG, J.C. Prevalence of Lawsonia intracellularis, Brachyspira hyodysenteriae and Salmonella in swine herds, Journal of Veterinary Science, v. 6, n. 4, p. 289-293, 2005 TOMATOV?, K., LITER?K, I., KLIMES, J. Lawsonia intracellularis in wild mammals in the Slovak Carpathians , Journal of Wildlife Disease, v.39, n.2, p. 407-411, 2003 87 UMEMURA, T.; TSUCHITANI, M.; TOTSUKA, M.; NARAME, I.; YAMACHIRO, S. Histiocytic Enteritis of Rabbits, Veterinary Pathology, v. 19, p. 326-28, 1982 WATARAI, M., YAMATO, Y., HORIUCHI, N.; KIM, S.; OMATA, Y.; SHIRAHATA, T.; FURUOKA, H. Enzyme-Linked Immunosorbent Assay to Detect Lawsonia intracellularis in rabbits with Proliferative Enteropathy, Journal of Veterinary Medical Science, v. 66, n. 6, p. 735-737, 2004 WATARAI, M., YAMATO, Y., MURAKATA, K.; KIM, S.; OMATA, Y.; FURUOKA, H. Detection of Lawsonia intracellularis Using Immunomagnetic Beads and ATP Bioluminescence, Journal of Veterinary Science, v. 67, n. 4, p. 449-451, 2005 WUERSCH, K.; HUESSY, D.; KOCH, K., Lawsonia intracellularis Proliferative Enteropathy in a Filly, Journal of Veterinary Medicine, v. 53, p. 17?21, 2006 YATES, W.D.G.; CLARK, E.G.; OSBORNE, A.D.; ENWEANI, C.C.; RADOSTITS, O.M.; THEEDE, A. Proliferative Hemorrhagic Enteropathy: An Outbreak and Review of the literature, Canadian Veterinary Journal, v. 20, p. 261-268, 1979 YEH, J.Y.; KIM, T.J.; PARK, S.Y.; SONG, S.G.; YOON, Y.D.; KIM, S.K.; LEE, J.B.; CHOI, I.S. Isolation of Lawsonia intracellularis in Korea and reproduction of proliferative enteropathy in pigs and hamsters, Journal of Veterinary Medicine Science, v. 68, n.5, p. 499-501, 2006
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