Efic?cia do Sarolaner no tratamento de mi?ases em c?es causadas por Dermatobia hominis (Diptera: Cutebridae)

Detalhes bibliográficos
Ano de defesa: 2020
Autor(a) principal: Andriotti, Paula Azevedo lattes
Orientador(a): Fernandes, J?lio Israel lattes
Banca de defesa: Fernandes, J?lio Israel, Balthazar, Daniel de Almeida, Cirne, Lilian Cristina de Souza Oliveira Batista
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Federal Rural do Rio de Janeiro
Programa de Pós-Graduação: Programa de P?s-Gradua??o em Medicina Veterin?ria (Patologia e Ci?ncias Cl?nicas)
Departamento: Instituto de Veterin?ria
País: Brasil
Palavras-chave em Português:
berne
sarolaner
larvicida
Palavras-chave em Inglês:
larvicide
Área do conhecimento CNPq:
Medicina Veterin?ria
Link de acesso: https://tede.ufrrj.br/jspui/handle/jspui/6319
Resumo: Lesions caused by breeds are quite uncomfortable and painful for dogs, and can cause secondary bacterial infections and predispose to other myiasis. Effective treatment should eliminate or kill existing larvae and promote wound healing as early as possible. However, currently, the recommended treatment for this parasite consists of manual removal of the larvae, which causes a lot of discomfort for the parasitized animal, so much so that, in some cases, there is a need for sedation to perform the procedure. The aim of this study was to evaluate the bernicidal efficacy of sarolaner for the treatment of Dermatobia hominis in naturally infested dogs. Ten mongrel dogs were included, aged between one and ten years, regardless of the sex variable, weighing between 11.4 and 19.1 kg, with at least three larvae. In total 75 larvae were counted, with an average of 7.5 larvae per animal. Most of the parasitism (46 larvae) was located in the lateral region of the animals. The animals were medicated with sarolaner at a dose of 2.0 mg / kg, administered orally in a single dose, following the recommendations in the package insert for the treatment of other ectoparasitoses. After treatment, the animals were kept in their homes and observations were made to verify the elimination activity and the bernicidal effect of the drug after 24 hours of medication administration. Any parasite that showed motility after mechanical removal was considered a live larva. As criteria for assessing the efficacy of sarolaner, the larvicidal effect was calculated for each animal using the formula: [Number of live larvae after treatment - number of live larvae before treatment) / Number of live larvae before treatment] ? 100. After 24 hours after medication administration, all larvae were found dead, although located in the animals' dermis. No animal had an adverse effect or behavior change after using isoxazoline. It is concluded that sarolaner administered in a single dose of 2.0mg / kg, orally, was 100% effective in dogs naturally infested by D. hominis.
id UFRRJ-1_e32e52807cb2241900bbd6c50b16fb9f
oai_identifier_str oai:localhost:jspui/6319
network_acronym_str UFRRJ-1
network_name_str Biblioteca Digital de Teses e Dissertações da UFRRJ
repository_id_str
spelling Fernandes, J?lio Israel082.100.187-60http://lattes.cnpq.br/9221592908532393Fernandes, J?lio IsraelBalthazar, Daniel de AlmeidaCirne, Lilian Cristina de Souza Oliveira Batista140.711.147-70http://lattes.cnpq.br/9447255004002929Andriotti, Paula Azevedo2023-02-07T17:05:34Z2020-02-20ANDRIOTTI, Paula Azevedo. Efic?cia do Sarolaner no tratamento de mi?ases em c?es causadas por Dermatobia hominis (Diptera: Cutebridae). 2020. 46 f. Disserta??o (Mestrado em Medicina Veterin?ria, Ci?ncias Cl?nicas) - Instituto de Veterin?ria, Universidade Federal Rural do Rio de Janeiro, Serop?dica, RJ, 2020.https://tede.ufrrj.br/jspui/handle/jspui/6319Lesions caused by breeds are quite uncomfortable and painful for dogs, and can cause secondary bacterial infections and predispose to other myiasis. Effective treatment should eliminate or kill existing larvae and promote wound healing as early as possible. However, currently, the recommended treatment for this parasite consists of manual removal of the larvae, which causes a lot of discomfort for the parasitized animal, so much so that, in some cases, there is a need for sedation to perform the procedure. The aim of this study was to evaluate the bernicidal efficacy of sarolaner for the treatment of Dermatobia hominis in naturally infested dogs. Ten mongrel dogs were included, aged between one and ten years, regardless of the sex variable, weighing between 11.4 and 19.1 kg, with at least three larvae. In total 75 larvae were counted, with an average of 7.5 larvae per animal. Most of the parasitism (46 larvae) was located in the lateral region of the animals. The animals were medicated with sarolaner at a dose of 2.0 mg / kg, administered orally in a single dose, following the recommendations in the package insert for the treatment of other ectoparasitoses. After treatment, the animals were kept in their homes and observations were made to verify the elimination activity and the bernicidal effect of the drug after 24 hours of medication administration. Any parasite that showed motility after mechanical removal was considered a live larva. As criteria for assessing the efficacy of sarolaner, the larvicidal effect was calculated for each animal using the formula: [Number of live larvae after treatment - number of live larvae before treatment) / Number of live larvae before treatment] ? 100. After 24 hours after medication administration, all larvae were found dead, although located in the animals' dermis. No animal had an adverse effect or behavior change after using isoxazoline. It is concluded that sarolaner administered in a single dose of 2.0mg / kg, orally, was 100% effective in dogs naturally infested by D. hominis.As les?es causadas por bernes s?o bastante desconfort?veis e dolorosas para os c?es, podendo causar infec??es bacterianas secund?rias e predispor a outras mi?ases. Um tratamento eficaz deve eliminar ou matar as larvas existentes e promover a cicatriza??o da ferida o mais precoce poss?vel. Entretanto, atualmente, o tratamento recomendado para esse parasito consiste na retirada manual das larvas, o que causa muito desconforto para o animal parasitado, tanto que, em alguns casos, h? a necessidade de seda??o para realiza??o do procedimento. O objetivo deste estudo foi avaliar a efic?cia bernicida do sarolaner para o tratamento de Dermatobia hominis em c?es naturalmente infestados. Foram inclu?dos dez c?es, sem ra?a definida, com idade variando entre dois e seis anos, independente da vari?vel sexo, com peso entre 11,4 e 19,1 kg, com no m?nimo tr?s larvas. No total foram contabilizadas 75 larvas, com m?dia de 7,5 larvas por animal. A maior parte do parasitismo (46 larvas) estava localizado na regi?o lateral dos animais. Os animais foram medicados com sarolaner na dose de 2,0 mg/kg, administrado por via oral em dose ?nica, seguindo as recomenda??es em bula para o tratamento de outras ectoparasitoses. Ap?s o tratamento, os animais foram mantidos em seus domic?lios e foram feitas observa??es para verificar a atividade de elimina??o e o efeito bernicida do f?rmaco ap?s 24 horas da administra??o da medica??o. Foi considerada larva viva qualquer parasito que apresentasse motilidade ap?s remo??o mec?nica. Como crit?rios de avalia??o da efic?cia do sarolaner, o efeito larvicida foi calculado para cada animal pela f?rmula: [N?mero de larvas vivas ap?s o tratamento ? n?mero de larvas vivas antes do tratamento) / N?mero de larvas vivas antes do tratamento] ? 100. Ap?s 24 horas da administra??o da medica??o todas as larvas foram encontradas mortas, ainda que localizadas na derme dos animais. Nenhum animal apresentou efeito adverso ou altera??o do comportamento ap?s a utiliza??o da isoxazolina. Conclui-se que o sarolaner administrado em dose ?nica de 2,0mg/kg, por via oral, foi 100% eficaz em c?es naturalmente infestados por D. hominis.Submitted by Jorge Silva (jorgelmsilva@ufrrj.br) on 2023-02-07T17:05:34Z No. of bitstreams: 1 2020 - Paula Azevedo Andriotti.Pdf: 2355562 bytes, checksum: f818e8478a2807e3bd8e4a2817234bc3 (MD5)Made available in DSpace on 2023-02-07T17:05:34Z (GMT). No. of bitstreams: 1 2020 - Paula Azevedo Andriotti.Pdf: 2355562 bytes, checksum: f818e8478a2807e3bd8e4a2817234bc3 (MD5) Previous issue date: 2020-02-20CAPES - Coordena??o de Aperfei?oamento de Pessoal de N?vel Superiorapplication/pdfhttps://tede.ufrrj.br/retrieve/72140/2020%20-%20Paula%20Azevedo%20Andriotti.Pdf.jpgporUniversidade Federal Rural do Rio de JaneiroPrograma de P?s-Gradua??o em Medicina Veterin?ria (Patologia e Ci?ncias Cl?nicas)UFRRJBrasilInstituto de Veterin?riaAIELLO, S.E. Parasitic Skin Diseases. In: AIELLO, S.E. The Merck veterinary manual. Philadelphia: National Publishing, p.631-632,1998. ANDERSEN, E.H. Control of Dermatobia hominis in Central America. Vet Rec, 74: 784-787, 1962. BECSKEI, C. et al. Efficacy and safety of a novel oral isoxazoline, sarolaner (Simparica?) in the treatment of naturally occurring flea and tick infestation in dogs presented as veterinary patients in Europe. Veterinary Parasitology, v. 222, p. 49-55, 2016a. BECSKEI, C. et al. Comparative speed of kill of oral treatments with Simparica TM (sarolaner) and Bravecto? (fluralaner) against induced infestations of Rhipicephalus sanguineus on dogs. Parasites & Vectors, v. 9, p. 103, 2016b. BEUGNET, F. & FRANC, M. Insecticide and acaricide molecules and/or combinations to prevent pet inffestation by ectoparasites. Trends in Parasitology, 28:267-279, 2012. BEUGNET, F.; LIEBENBERG, J.; HALOS, L. Comparative efficacy of two oral treatments for dogs containing either afoxolaner or fluralaner against Rhipicephalus sanguineus sensu lato and Dermacentor reticulatus. Veterinary Parasitology, v.209, n.1-2, p.142-145, 2015. BOURDEAU, P.; KLAP, D.E.; MIALOT, M. Myiase ? Dermatobia hominis. A prop?s d?um cas observe chez le chien. Recueil de M?dicin V?t?rinaire, v.164, p.901-906, 1988. BORJA, G. M. Erradica??o ou manejo integrado das mi?ases neotropicais das Americas. Pesquisa Veterin?ria Brasileira, 23(32): 131-138, jul/set.2003. BOWMAN, A. Dermatobia hominis. American Association of Veterinary Parasitologists, 2014. At: https://aavp.org/wiki/arthropods/insects/cuteribridae/dermatobiahominis. Acessado em: 12 de novembro de 2019. BRAM, R.A.; GEORGE, J.E.; REICHARD, R.E.; TABACHNICK, W.J. Threat of foreign arthropod-borne pathogens to livestock in the United States. Journal of Medical Entomology, v.39, p.405-416,2001. BRITO, L.G.; BORJA, M.G.E. Flutua??o sazonal de Dermatobia hominis em peles bovinas oriundas de matadouros. Pesquisa Veterin?ria, Bras.20(4): 151-154, 2000. BRITO, L.G.; PAES M.J & BORJA, M.G.E. Infesta??o artificial e desenvolvimento larval de Dermatobia hominis (L.jr., 1781)(Diptera: Cuterebridae) em su?nos e equinos. Revista Ceres, 48 (277): 401-403, 2001. CAMPOS, D.R. et al. Efic?cia da associa??o de cipermetrina, clorpirif?s, but?xido de piperonila e fluazuron contra larvas de Dermatobia hominis em bovinos naturalmente infestados. Brazilian Journal of Veterinary Medicine, 39(1), 28-32, 2017. CASIDA, J. E.; DURKIN, K. A. Novel GABA receptor pesticide targets. Pesticide Biochemistry and Physiology, v.121, p.2-30, 2015. CARDONA, E.A.; Sarcopromusca pruna (Dipera: Muscidae): phoretic for Dermatobia hominis (Diptera:cuterebridae) eggs in colombia. Vet Colomb Cien Pecu, v. 24; p. 577-584, 2011. CARDOZO, S. V.; RAMADINHA, R.R. Avalia??o do tratamento de mi?ases em c?es atrav?s da utiliza??o do nitenpyran. Revista Brasileira de Ci?ncia Veterin?ria, v.14, n.3, p. 139-142, 2007. CAVALLERI, D. et al. Assessment of the speed of flea kill of lotilaner (Credelio?) throughout the month following oral administration to dogs. Parasites & vectors, v.10, s.1, p.529, 2017. COELHO, C.N et al. Associa??o de abamectina com fluazuron no controle de Dermatobia hominis em bovinos naturalmente infestados. Revista Brasileira de Medicina Veterin?ria, v. 37(Supl.1):91-94, 2015. CRAMER-RIBEIRO, B. C. et al. Inqu?rito sobre os casos de mi?ase por Dermatobia hominis em c?es da zona sul do munic?pio do Rio de Janeiro no ano de 2000. Brazilian Journal of veterinary Research and Animal Science, v.39,n.4, p. 176-180, 2002. CURTIS, M.P. et al. Design and synthesis of sarolaner, a novel, once-a-month, oral isoxazoline for the control of fleas and ticks on dogs. Bioorganic & medicinal chemistry letters, v.26, n.7, p.1831-1835, 2016. DANIEL, E.; JULIAN, E. Efficacy of lotilaner a novel oral isoxazoline against naturally occurring mange mite infestations in dogs caused by Demodex spp. Parasites & Vectors, v.10, s1, p.532, 2017. DAWOOD, R. Diseases spread by insects. In: ?Travelers?s health: how to stay health abroad?. Oxford, Ny: Oxford University Press, p. 197, 2002. DE FILLIPS, T.; LEITE, A. Morphology of the second-and third-instar larvae of Dermatobia hominis by scanning electron microscopy. Medical and Veterinary entology, v. I12: 160-168, 1998. DRAG, M.; SAIK, J.; HARRIMAN, J. Safety evaluation of orally administered afoxolaner in 8-week-old dogs. Veterinary Parasitology, v.201, p.198-203, 2014. FERNANDES, N.L.M.; THOMAZ-SCOCCOL, V.; PINTO, S.B.; OLIVEIRA, C.A.L. Din?mica populacional e distribui??o corporal das larvas de Dermatobia hominis (Linnaeus Jr., 1781) em bovinos da ra?a nelore. Archives of veterinary Science, v.13, n.2, p.85-92, 2008. FORTES, E. Artropodologia. In: FORTES, E. Parasitologia veterin?ria. S?o Paulo: ?cone, p. 535-39, 1997. FRANCESCONI. F; LUPI, O. Myiasis. Clinical Microbiology Reviews, v. 25: 79-98, 2012. FURLONG, J; PRATA, M.C.A.; MARTINS, J.R. O carrapato dos bovinos e a Resistencia: Temos que comemorar? Hora veterin?ria, 27: 26-32, 2007. GARC?A-REYNAGA, P.; ZHAO, C.; SARPONG, R. New GABA/ Glutamate receptor target for hisoxazoline insecticide. Chemical Research in Toxicology, v.26, p.514-516, 2013. GASSEL, M. et al. The novel isoxazoline ectoparasiticide fluralaner: selective inhibition of arthropod ?-aminobutyric acid-and L-glutamate-gated chloride channels and insecticidal/acaricidal activity. Insect Biochemistry And Molecular Biology, v.45, p.111-124, 2014. GEURDEN, T. et al. HEfficacy of a novel oral formulation of sarolaner (Simparica?) against four common tick species infesting dogs in Europe. Veterinary Parasitology, v.222, p.33-36, 2016. GEURDEN, T. et al. Efficacy of a new spot-on formulation of selamectin plus sarolaner against four common tick species infesting cats in Europe. Veterinary parasitology, v.238, S3-S7, 2017b. GEURDEN, T. et al. Efficacy of a new spot-on formulation of selamectin plus sarolaner against Ancylostoma tubaeforme and Toxocara cati in cats. Veterinary Parasitology, v.238, S31-S35, 2017c. GEURDEN, T. et al. Comparative efficacy of a new spot-on combination product containing selamectin and sarolaner (Stronghold? Plus) versus fluralaner (Bravecto?) against induced infestations with Ixodes ricinus ticks on cats. Parasites & vectors, v.10, s.1, p.319, 2017d. GOMES R.P; KOLLER, W.W; GOMES, A., et al,. Dipteros fanideos vetores de ovos de Dermatobia hominis em Campo Grande, Mato Grosso do Sul. Pesquisa Veterin?ria, Bras. 22; 114-118, 2002. GODDARD, J. Flies whose maggots cause myiasis inhumans. In: Physician?s Guide to Arthropods of Medical Importance, 2nd edn. Florida CRC Press, p.169?187, 1996. GRISI, L.; MASSARD, C.L.; MOYA, G.E.; PEREIRA, J.B. Impacto econ?mico das principais ectoparasitoses em bovinos no Brasil. Hora Veterin?ria, v 2, p. 8-10, 2002. GUIMAR?ES, J.H; PAPAVERO, N.; PRADO, A.P. As mi?ases da Regi?o Neotropical. ReVevista Brasileira de Zoologia, v 1: 239-416, 1983. GUIMAR?ES, J. H.; PAPAVERO, N. Generalities about myiasis in the Neotropical Region. In: myiasis in Man and Animals in the Neotropical Region ? Bib ? Liographic Database. S?o Paulo: Pl?iade, a. 308p. Cap. 1, p. 16, 1998 a. HAN, H. S.; NOLI, C.; CENA, T. Efficacy and duration of action of oral fluralaner and spot?on moxidectin/imidacloprid in cats infested with Lynxacarus radovskyi. Veterinary dermatology, v.27, s.6, p.474-e127, 2016. HARWOOD, F.R; JAMES, M.T. In: Entomology in Human and Animal Health, 7th edition. Macmillan. New York, pp. 313-315, 1979. HOPE, F.W. On insects and their larvae occasionally found in the human body. Transactions of the Entomological Society of London, v. 2, pp. 256-271, 1840. HUNTER, J. S. et al. Evaluation of the curative and preventive efficacy of a single oral administration of afoxolaner against cat flea Ctenocephalides felis infestations on dogs. Veterinary Parasitology, v.201, p.207-211, 2014. IRWON, P.J.; JEFFERIES, R. Artropod- transmitted diseases of companion animals in Southeast Asia. Trends in Parasitology, v 1, 27-34. 2004. KARADZOVSKA, D.; CHAPPELL, K.; COBLE, S. A randomized, controlled field study to assess the efficacy and safety of lotilaner flavored chewable tablets (CredelioTM) in eliminating fleas in client-owned dogs in the USA. Parasites & Vectors, v.10, p.528, 2017. KHAN, D.G. Myiasis secondary to Dermatobia hominis (human botfly) presenting as a long-standingbreast mass. Archives of Pathology & Laboratory Medicine online, 123: 829-831, 1999. KILP, S.; RAMIREZ, D.; ALLAN, J. Comparative pharmacokinetics of fluralaner in dogs and cats following single topical or intravenous administration. Parasites & Vectors, v.9, p.296, 2016. KUNKLE, B. et al. Assessment of the efficacy of orally administered afoxolaner against Rhipicephalus sanguineus sensu lato. Veterinary parasitology, v.20, s.3-4, p.226-228, 2014b. LIEBERT.P, S; MADDEN.R, C. Human botfly larva in a child?s scalp. Journal Pediatric Surgury, 39: 490-491, 2004. LOBO, G.; ZELED?N, R. Algunos aspectos sobre l? populaci?n de Dermatobia hominis (L.jr.)(Diptera:Cuterebridae). Turrialba, v. 34(I):1-8.1984. MACHADO, M. A. et al. Efficacy of afoxolaner in the treatment of otodectic mange in naturally infested cats. Veterinary parasitology, v.256, p.29-31, 2018. MANDELL, G.; BENNET, J.; DOLIN, R. Chapter 293: Myiasis and tungiasis. In: Principles and Practice of infectious Diseases, 6th edn. 2004. Available at: http://o-www.mdconsult.com.innopac.library.unr.edu:80/das/book/body/924153734/695200800/1259/2373.html#4-ui.o-Bo-44306643-4..50296-8-cesecI_9I03, acessado 10 de maio de 2019. MARCHIONDO, A.A.; HOLDSWORTH, P.A.; FOURIE L.J.; RUGG D.; HELLMANN, K.; SNYDER, D.E.; DRYDEN, M.W. Guidelines for evaluating the efficacy of parasiticides for the treatment, prevention and control of flea and tick infestations on dogs and cats. 2nd ed. World Association for the Advancement of Veterinary Parasitology. Vet. Parasitol, 194(1):84-97, 2013. MARQUES, D.C. Ectoparasitos. In: Cria??o de bovinos. 7? ed. Belo Horizonte: CVP, 374pp, 2003. MARTY, F. M; WHITESIDE, K. R. Images in clinical medicine. Myiasis due to Dermatobia hominis (human botfly). The new England Journal Of Medicine, p.352: e2I, 2005. MCGRAW, T.; TURIANSKY, G. Cutaneous myiasis. Journal of the American Academy of Dermatology, v. 58: 907-926, 2008. MCTIER, T. L. et al. Discovery of sarolaner: a novel, orally administered, broad-spectrum, isoxazoline ectoparasiticide for dogs. Veterinary parasitology, v.222, p.3-11, 2016. MCTIER, T. L. et al. The efficacy of a novel topical formulation of selamectin plus sarolaner (Revolution Plus/ Stronghold Plus) in preventing the development of Dirofilaria immitis in cats. Veterinary Parasitology, v.270, p.56-62, 2019. MEDEIROS, D.C.; BAPTISTA, M.N.; BORJA, G.E.M. Frequ?ncia populacional de Dermatobia hominis (Linnaeus Jr., 1781) (Diptera: Cuterebridae) e sua correla??o com vari?veis clim?ticas, no sudeste do Brasil. Brazilian Journal Veterinary Research and Animal Science. S?o Paulo, v.52, n.4, p.350-355, 2015. MENDES ? DE- ALMEIDA, F.; LABARTHE, N.; GUERRERO,J . et al., Cochliomya hominivorax myiasis in a colony of mstray cats (felis catus Linnaeus, 1758) in Rio de Janeiro, Rj. Veterinary Parasitology, v. 146: 376-378, 2007. MOYA BORJA, G. E. Estudios sobre la biologia, morfologia y esterilizaci?n del t?rsalo, Dermatobia hominis (L.jr.). M.S.c. Thesis, IIca, Yurrialba, Costa Rica, p. 63, 1966. MOYA BORJA, G.E. Retrospectiva da dermatobiose ? biologia e epidemiologia da Dermatobia hominis. Anais da XI jornada cient?fica da UFRRJ, Campo Grande.p. 303-314, jul./ 1979. MOYA BORJA, G.E. Erradica??o ou manejo integrado das mi?ases neotropicais das Am?ricas? Pesquisa Veterin?ria Brasileira, v. 32:131-138, 2003. MURPHY, M. et al. Laboratory evaluations of the immediate and sustained efficacy of lotilaner (Credelio?) against four common species of ticks affecting dogs in North America. Parasites & vectors, v.10, s.1, p.523, 2017. NOUTIS,C.; MILLIKAN, L. E. Myiasis. Dermatology Clinical, v.12:81-83,1994. OZOE, Y.; ASAHI, M.; OZOE, F. The antiparasitic isoxazoline A1443 is a potent blocker of insect ligand-gated chloride channels. Biochemical Biophysical Res Commun, v.391, p.744-749, 2010. OLIVEIRA, P.C. et al. Efficacy of spinosad on the treatment of myiasis caused by Cochliomyia hominivorax (Diptera: Calliphoridae) in dogs. Veterinary Parasitology, v.258, p.53-56, 2018. PALLAI. L.; HODGE.J.;FISHMAN. S,J.; MILLIKAN. L,E.; PHELPS. R,G.; Case report: Myiasis- the botfly boil. The American journal Of The Medical Scienses, 303: 245-248.1992. PEREIRA. M,C, T.; LEITE, V.H.R.; LEITE, A.C.R. Experimental skin lesions from larvae of the bot fly Dermatobia hominis. Medical and Veterinary Entomology, v. 15: 22-27, 2001. PINOS, V.H.; ORTIZ PRADO, E.; BERMEO, C.; LE?N, J.; ARMIJOS, L.; ALMEIDA, E. Case Report: A unique case of facial burn superinfected with Dermatobia hominis larvae resulting in a bilateral enucleation of the eyes.Tropical . Tropical Doctor. Vol. 44 (4), pp. 235-237, 2014. RIBEIRO, B.C.C.; SANAVRIA, A.; MORAES, A. C.; REIS, T. P.; SOUZA, F.S. Ocorr?ncia de mi?ases por Dermatobia hominis (Cuterebridae) em c?es procedentes da ?rea rural do Estado do Rio de Janeiro em Dezembro de 2000. Anais da XI jornada de Inicia??o Cientifica da UFRRJ. V. 11, p. 141-144, 2001. ROBBINS, K.; KHACHEMOUNE, A.C.W.S. Review: Cutaneous myiasis: a review of the common types of myiasis. International Journal of Dermatology, v. 49, pp. 1092-1098, 2010. RONCALLI, R.A. The biology and control of Dermatobia hominis, the tropical warble-fly of latin America. Preventive Veterinary Medicine, 2: 569-678,1984. ROOSJE, P.J.; HENDRIKY, W.M.L.; WISSELINK, M. A. & WILLEMSE, T. A case of a Dermatobia hominis infection in a dog in the Netherland. Veterinary Dermatology, vol 3, n?4/5, pp. 183-185, 1992. SANAVRIA, A.; BARBOSA, C.G.; BEZERRA, E.S.; MORAIS, M.C.; GIUPPONI, P. . Distribui??o de larvas de Dermatobia hominis (Linnaeus Jr.; 1781)(Diptera: Cuterebridae) em peles de bovinos. Parasitologia Latinoamericana, v. 57, p. 21-24, 2002. SCOTT, F. et al. Efficacy of sarolaner (Simparica?) against induced infestations of Amblyomma cajennense on dogs. Parasites & Vectors, v.10, s.1, p.390, 2017. SHAW, S.E.; DAY, M.J. Arthropod-borne infectious Diseases of the dog and cat. Manson Publishing, pp.9-10, London, 2005. SIX, R.H. et al. Efficacy of sarolaner, a novel oral isoxazoline, against two common mite infestations in dogs: Demodex spp. and Otodectes cynotis . Veterinary Parasitology, v. 222, p.62-69, 2016a. SIX, R.H. et al. Evaluation of the speed of kill of sarolaner (Simparica?) against induced infestations of three species of ticks (Amblyomma maculatum, Ixodes scapularis, Ixodes ricinus) on dogs. Veterinary Parasitology, v.222, p.37-42, 2016b. SIX, R.H. et al. Efficacy of a novel oral formulation of sarolaner (Simparica?) against five common tick species infesting dogs in the United States. Veterinary Parasitology, v.222, p.28?32, 2016d. SOJKA, P.A. Therapeutic review?isoxazolines. Journal of Exotic Pet Medicine, v.27, p. 118-122, 2018. TAENZLER, J. et al. Onset of activity of fluralaner (BRAVECTO?) against Ctenocephalides felis on dogs. Parasites & Vectors, v.7, s.1, p.567, 2014. TAENZLER, J. et al. Efficacy of fluralaner against Otodectes cynotis infestations in dogs and cats. Parasites & Vectors, v.10, s.1, p.30, 2017. TOUTAIN, C. E.; SEEWALD, W.; JUNG, M. The intravenous and oral pharmacokinetics of lotilaner in dogs. Parasites & Vectors, v.10, s.1, p.522, 2017. URQUHART, G.M.; ARMOUR, J.; DUNCAN, J. L.; DUNN, A. M.; JENNINGS, F. W. Entomologia Veterin?ria. In: URQUHART, G.M.; ARMOUR, J.; DUNCAN, J. L.; DUNN, A. M.; JENNINGS, F. W. Parasitologia Veterin?ria. Rio de Janeiro: Guanabara, p. 175-176, 1990. VARLOUD, M.; FOURIE, J. J. Onset of efficacy and residual speed of kill over one month of a topical dinotefuran-permethrin-pyriproxyfen combination (Vectra? 3D) against the adult cat flea (Ctenocephalides felis felis) on dogs. Veterinary Parasitology, v.211, s.1-2, p.89-92, 2015. VATTA, A. F. et al. Efficacy of a new spot-on formulation of selamectin plus sarolaner for cats against adult Ctenocephalides felis, flea egg production and adult flea emergence. Veterinary parasitology, v.238, S22-S26, 2017. VATTA, A. F. et al. Comparative efficacy of topical treatments with Revolution Plus (selamectin and sarolaner) and Bravecto for cats (fluralaner) against Ixodes scapularis ticks on cats. Veterinary parasitology, v.270, S58-S63, 2019b. VILLALOBOS. G.; VEGA - MEMIJE. M, E.; MARAVILLA. P.; MARTINEZ- HERNANDEZ, F. Review: Myiasis caused by Dermatobia hominis: countries with increased risk for travelers going to neotropic areas. International Journal of Dermatology, v. 55, p. 1060-1068, 2016. VERANI, S.; TASSINARI, D.;ELLERI, D, et al. A case of furuncular myiasis associated with systemic inflammation. International Journal for Parasitology, v. 56:330-333, 2007. WALTHER, F.M. et al. Safety of fluralaner, a novel systemic antiparasitic drug, in MDR1 (-/-) Collies after oral administration. Parasites & Vectors, v.7, s.86, 2014a. WEBER, T.; SELZER, P.M. Isoxazolines: A novel chemotype higly effective on ectoparasites. Chemmedchem Minireviews, v. 11, p.270-276, 2016. WILLWMSE, T. Doen?as Parasit?rias. In: WILLEMSE, T. Dermatologia cl?nica de c?es e gatos. S?o Paulo: Manole, p. 27-39, 1998. WISMER, T.; MEANS, C. Toxicology of newer insecticides in small animals. Veterinary of North America: Small Animal Practice, v.42, s.2, 2012. WOODS, D.J.; MCTIER T.L.; DEROSA, A.A. Comparison of the Anti-ectoparasite and Anti-endoparasite Therapies and Control Strategies. In: Ectoparasites ? Drug Discovery Against Moving Targets, v.8, p.3-24, 2018. WOODS, D.J.; MCTIER, T.L. Discovery, development and commercialization of sarolaner (Simparica?), a novel oral isozaxoline ectoparasiticide for dogs. In: Ectoparasites ? Drug Discovery Against Moving Targets, v.8, p. 295-318, 2018. ZAKSON-AIKEN, M. et al. Systemic activity of the avermectins against the cat flea, Ctenocephalides felis (Siphonaptera: Pulicidae). Journal of the Medical Entomology, v.38, n.4, p.576-580, 2000.bernesarolanerlarvicidalarvicideMedicina Veterin?riaEfic?cia do Sarolaner no tratamento de mi?ases em c?es causadas por Dermatobia hominis (Diptera: Cutebridae)Efficacy of Sarolaner in the treatment of myiasis in dogs caused by Dermatobia hominis (Diptera: Cutebridae)info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisinfo:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da UFRRJinstname:Universidade Federal Rural do Rio de Janeiro (UFRRJ)instacron:UFRRJTHUMBNAIL2020 - Paula Azevedo Andriotti.Pdf.jpg2020 - Paula Azevedo Andriotti.Pdf.jpgimage/jpeg1943http://localhost:8080/tede/bitstream/jspui/6319/4/2020+-+Paula+Azevedo+Andriotti.Pdf.jpgcc73c4c239a4c332d642ba1e7c7a9fb2MD54TEXT2020 - Paula Azevedo Andriotti.Pdf.txt2020 - Paula Azevedo Andriotti.Pdf.txttext/plain69919http://localhost:8080/tede/bitstream/jspui/6319/3/2020+-+Paula+Azevedo+Andriotti.Pdf.txt5a1172fd66775aa26a5c4d5196a24fe6MD53ORIGINAL2020 - Paula Azevedo Andriotti.Pdf2020 - Paula Azevedo Andriotti.Pdfapplication/pdf2355562http://localhost:8080/tede/bitstream/jspui/6319/2/2020+-+Paula+Azevedo+Andriotti.Pdff818e8478a2807e3bd8e4a2817234bc3MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-82089http://localhost:8080/tede/bitstream/jspui/6319/1/license.txt7b5ba3d2445355f386edab96125d42b7MD51jspui/63192023-02-08 02:00:24.242oai:localhost: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Biblioteca Digital de Teses e Dissertaçõeshttps://tede.ufrrj.br/PUBhttps://tede.ufrrj.br/oai/requestbibliot@ufrrj.br||bibliot@ufrrj.bropendoar:2023-02-08T04:00:24Biblioteca Digital de Teses e Dissertações da UFRRJ - Universidade Federal Rural do Rio de Janeiro (UFRRJ)false
dc.title.por.fl_str_mv Efic?cia do Sarolaner no tratamento de mi?ases em c?es causadas por Dermatobia hominis (Diptera: Cutebridae)
dc.title.alternative.eng.fl_str_mv Efficacy of Sarolaner in the treatment of myiasis in dogs caused by Dermatobia hominis (Diptera: Cutebridae)
title Efic?cia do Sarolaner no tratamento de mi?ases em c?es causadas por Dermatobia hominis (Diptera: Cutebridae)
spellingShingle Efic?cia do Sarolaner no tratamento de mi?ases em c?es causadas por Dermatobia hominis (Diptera: Cutebridae)
Andriotti, Paula Azevedo
berne
sarolaner
larvicida
larvicide
Medicina Veterin?ria
title_short Efic?cia do Sarolaner no tratamento de mi?ases em c?es causadas por Dermatobia hominis (Diptera: Cutebridae)
title_full Efic?cia do Sarolaner no tratamento de mi?ases em c?es causadas por Dermatobia hominis (Diptera: Cutebridae)
title_fullStr Efic?cia do Sarolaner no tratamento de mi?ases em c?es causadas por Dermatobia hominis (Diptera: Cutebridae)
title_full_unstemmed Efic?cia do Sarolaner no tratamento de mi?ases em c?es causadas por Dermatobia hominis (Diptera: Cutebridae)
title_sort Efic?cia do Sarolaner no tratamento de mi?ases em c?es causadas por Dermatobia hominis (Diptera: Cutebridae)
author Andriotti, Paula Azevedo
author_facet Andriotti, Paula Azevedo
author_role author
dc.contributor.advisor1.fl_str_mv Fernandes, J?lio Israel
dc.contributor.advisor1ID.fl_str_mv 082.100.187-60
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/9221592908532393
dc.contributor.referee1.fl_str_mv Fernandes, J?lio Israel
dc.contributor.referee2.fl_str_mv Balthazar, Daniel de Almeida
dc.contributor.referee3.fl_str_mv Cirne, Lilian Cristina de Souza Oliveira Batista
dc.contributor.authorID.fl_str_mv 140.711.147-70
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/9447255004002929
dc.contributor.author.fl_str_mv Andriotti, Paula Azevedo
contributor_str_mv Fernandes, J?lio Israel
Fernandes, J?lio Israel
Balthazar, Daniel de Almeida
Cirne, Lilian Cristina de Souza Oliveira Batista
dc.subject.por.fl_str_mv berne
sarolaner
larvicida
topic berne
sarolaner
larvicida
larvicide
Medicina Veterin?ria
dc.subject.eng.fl_str_mv larvicide
dc.subject.cnpq.fl_str_mv Medicina Veterin?ria
description Lesions caused by breeds are quite uncomfortable and painful for dogs, and can cause secondary bacterial infections and predispose to other myiasis. Effective treatment should eliminate or kill existing larvae and promote wound healing as early as possible. However, currently, the recommended treatment for this parasite consists of manual removal of the larvae, which causes a lot of discomfort for the parasitized animal, so much so that, in some cases, there is a need for sedation to perform the procedure. The aim of this study was to evaluate the bernicidal efficacy of sarolaner for the treatment of Dermatobia hominis in naturally infested dogs. Ten mongrel dogs were included, aged between one and ten years, regardless of the sex variable, weighing between 11.4 and 19.1 kg, with at least three larvae. In total 75 larvae were counted, with an average of 7.5 larvae per animal. Most of the parasitism (46 larvae) was located in the lateral region of the animals. The animals were medicated with sarolaner at a dose of 2.0 mg / kg, administered orally in a single dose, following the recommendations in the package insert for the treatment of other ectoparasitoses. After treatment, the animals were kept in their homes and observations were made to verify the elimination activity and the bernicidal effect of the drug after 24 hours of medication administration. Any parasite that showed motility after mechanical removal was considered a live larva. As criteria for assessing the efficacy of sarolaner, the larvicidal effect was calculated for each animal using the formula: [Number of live larvae after treatment - number of live larvae before treatment) / Number of live larvae before treatment] ? 100. After 24 hours after medication administration, all larvae were found dead, although located in the animals' dermis. No animal had an adverse effect or behavior change after using isoxazoline. It is concluded that sarolaner administered in a single dose of 2.0mg / kg, orally, was 100% effective in dogs naturally infested by D. hominis.
publishDate 2020
dc.date.issued.fl_str_mv 2020-02-20
dc.date.accessioned.fl_str_mv 2023-02-07T17:05:34Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.citation.fl_str_mv ANDRIOTTI, Paula Azevedo. Efic?cia do Sarolaner no tratamento de mi?ases em c?es causadas por Dermatobia hominis (Diptera: Cutebridae). 2020. 46 f. Disserta??o (Mestrado em Medicina Veterin?ria, Ci?ncias Cl?nicas) - Instituto de Veterin?ria, Universidade Federal Rural do Rio de Janeiro, Serop?dica, RJ, 2020.
dc.identifier.uri.fl_str_mv https://tede.ufrrj.br/jspui/handle/jspui/6319
identifier_str_mv ANDRIOTTI, Paula Azevedo. Efic?cia do Sarolaner no tratamento de mi?ases em c?es causadas por Dermatobia hominis (Diptera: Cutebridae). 2020. 46 f. Disserta??o (Mestrado em Medicina Veterin?ria, Ci?ncias Cl?nicas) - Instituto de Veterin?ria, Universidade Federal Rural do Rio de Janeiro, Serop?dica, RJ, 2020.
url https://tede.ufrrj.br/jspui/handle/jspui/6319
dc.language.iso.fl_str_mv por
language por
dc.relation.references.por.fl_str_mv AIELLO, S.E. Parasitic Skin Diseases. In: AIELLO, S.E. The Merck veterinary manual. Philadelphia: National Publishing, p.631-632,1998. ANDERSEN, E.H. Control of Dermatobia hominis in Central America. Vet Rec, 74: 784-787, 1962. BECSKEI, C. et al. Efficacy and safety of a novel oral isoxazoline, sarolaner (Simparica?) in the treatment of naturally occurring flea and tick infestation in dogs presented as veterinary patients in Europe. Veterinary Parasitology, v. 222, p. 49-55, 2016a. BECSKEI, C. et al. Comparative speed of kill of oral treatments with Simparica TM (sarolaner) and Bravecto? (fluralaner) against induced infestations of Rhipicephalus sanguineus on dogs. Parasites & Vectors, v. 9, p. 103, 2016b. BEUGNET, F. & FRANC, M. Insecticide and acaricide molecules and/or combinations to prevent pet inffestation by ectoparasites. Trends in Parasitology, 28:267-279, 2012. BEUGNET, F.; LIEBENBERG, J.; HALOS, L. Comparative efficacy of two oral treatments for dogs containing either afoxolaner or fluralaner against Rhipicephalus sanguineus sensu lato and Dermacentor reticulatus. Veterinary Parasitology, v.209, n.1-2, p.142-145, 2015. BOURDEAU, P.; KLAP, D.E.; MIALOT, M. Myiase ? Dermatobia hominis. A prop?s d?um cas observe chez le chien. Recueil de M?dicin V?t?rinaire, v.164, p.901-906, 1988. BORJA, G. M. Erradica??o ou manejo integrado das mi?ases neotropicais das Americas. Pesquisa Veterin?ria Brasileira, 23(32): 131-138, jul/set.2003. BOWMAN, A. Dermatobia hominis. American Association of Veterinary Parasitologists, 2014. At: https://aavp.org/wiki/arthropods/insects/cuteribridae/dermatobiahominis. Acessado em: 12 de novembro de 2019. BRAM, R.A.; GEORGE, J.E.; REICHARD, R.E.; TABACHNICK, W.J. Threat of foreign arthropod-borne pathogens to livestock in the United States. Journal of Medical Entomology, v.39, p.405-416,2001. BRITO, L.G.; BORJA, M.G.E. Flutua??o sazonal de Dermatobia hominis em peles bovinas oriundas de matadouros. Pesquisa Veterin?ria, Bras.20(4): 151-154, 2000. BRITO, L.G.; PAES M.J & BORJA, M.G.E. Infesta??o artificial e desenvolvimento larval de Dermatobia hominis (L.jr., 1781)(Diptera: Cuterebridae) em su?nos e equinos. Revista Ceres, 48 (277): 401-403, 2001. CAMPOS, D.R. et al. Efic?cia da associa??o de cipermetrina, clorpirif?s, but?xido de piperonila e fluazuron contra larvas de Dermatobia hominis em bovinos naturalmente infestados. Brazilian Journal of Veterinary Medicine, 39(1), 28-32, 2017. CASIDA, J. E.; DURKIN, K. A. Novel GABA receptor pesticide targets. Pesticide Biochemistry and Physiology, v.121, p.2-30, 2015. CARDONA, E.A.; Sarcopromusca pruna (Dipera: Muscidae): phoretic for Dermatobia hominis (Diptera:cuterebridae) eggs in colombia. Vet Colomb Cien Pecu, v. 24; p. 577-584, 2011. CARDOZO, S. V.; RAMADINHA, R.R. Avalia??o do tratamento de mi?ases em c?es atrav?s da utiliza??o do nitenpyran. Revista Brasileira de Ci?ncia Veterin?ria, v.14, n.3, p. 139-142, 2007. CAVALLERI, D. et al. Assessment of the speed of flea kill of lotilaner (Credelio?) throughout the month following oral administration to dogs. Parasites & vectors, v.10, s.1, p.529, 2017. COELHO, C.N et al. Associa??o de abamectina com fluazuron no controle de Dermatobia hominis em bovinos naturalmente infestados. Revista Brasileira de Medicina Veterin?ria, v. 37(Supl.1):91-94, 2015. CRAMER-RIBEIRO, B. C. et al. Inqu?rito sobre os casos de mi?ase por Dermatobia hominis em c?es da zona sul do munic?pio do Rio de Janeiro no ano de 2000. Brazilian Journal of veterinary Research and Animal Science, v.39,n.4, p. 176-180, 2002. CURTIS, M.P. et al. Design and synthesis of sarolaner, a novel, once-a-month, oral isoxazoline for the control of fleas and ticks on dogs. Bioorganic & medicinal chemistry letters, v.26, n.7, p.1831-1835, 2016. DANIEL, E.; JULIAN, E. Efficacy of lotilaner a novel oral isoxazoline against naturally occurring mange mite infestations in dogs caused by Demodex spp. Parasites & Vectors, v.10, s1, p.532, 2017. DAWOOD, R. Diseases spread by insects. In: ?Travelers?s health: how to stay health abroad?. Oxford, Ny: Oxford University Press, p. 197, 2002. DE FILLIPS, T.; LEITE, A. Morphology of the second-and third-instar larvae of Dermatobia hominis by scanning electron microscopy. Medical and Veterinary entology, v. I12: 160-168, 1998. DRAG, M.; SAIK, J.; HARRIMAN, J. Safety evaluation of orally administered afoxolaner in 8-week-old dogs. Veterinary Parasitology, v.201, p.198-203, 2014. FERNANDES, N.L.M.; THOMAZ-SCOCCOL, V.; PINTO, S.B.; OLIVEIRA, C.A.L. Din?mica populacional e distribui??o corporal das larvas de Dermatobia hominis (Linnaeus Jr., 1781) em bovinos da ra?a nelore. Archives of veterinary Science, v.13, n.2, p.85-92, 2008. FORTES, E. Artropodologia. In: FORTES, E. Parasitologia veterin?ria. S?o Paulo: ?cone, p. 535-39, 1997. FRANCESCONI. F; LUPI, O. Myiasis. Clinical Microbiology Reviews, v. 25: 79-98, 2012. FURLONG, J; PRATA, M.C.A.; MARTINS, J.R. O carrapato dos bovinos e a Resistencia: Temos que comemorar? Hora veterin?ria, 27: 26-32, 2007. GARC?A-REYNAGA, P.; ZHAO, C.; SARPONG, R. New GABA/ Glutamate receptor target for hisoxazoline insecticide. Chemical Research in Toxicology, v.26, p.514-516, 2013. GASSEL, M. et al. The novel isoxazoline ectoparasiticide fluralaner: selective inhibition of arthropod ?-aminobutyric acid-and L-glutamate-gated chloride channels and insecticidal/acaricidal activity. Insect Biochemistry And Molecular Biology, v.45, p.111-124, 2014. GEURDEN, T. et al. HEfficacy of a novel oral formulation of sarolaner (Simparica?) against four common tick species infesting dogs in Europe. Veterinary Parasitology, v.222, p.33-36, 2016. GEURDEN, T. et al. Efficacy of a new spot-on formulation of selamectin plus sarolaner against four common tick species infesting cats in Europe. Veterinary parasitology, v.238, S3-S7, 2017b. GEURDEN, T. et al. Efficacy of a new spot-on formulation of selamectin plus sarolaner against Ancylostoma tubaeforme and Toxocara cati in cats. Veterinary Parasitology, v.238, S31-S35, 2017c. GEURDEN, T. et al. Comparative efficacy of a new spot-on combination product containing selamectin and sarolaner (Stronghold? Plus) versus fluralaner (Bravecto?) against induced infestations with Ixodes ricinus ticks on cats. Parasites & vectors, v.10, s.1, p.319, 2017d. GOMES R.P; KOLLER, W.W; GOMES, A., et al,. Dipteros fanideos vetores de ovos de Dermatobia hominis em Campo Grande, Mato Grosso do Sul. Pesquisa Veterin?ria, Bras. 22; 114-118, 2002. GODDARD, J. Flies whose maggots cause myiasis inhumans. In: Physician?s Guide to Arthropods of Medical Importance, 2nd edn. Florida CRC Press, p.169?187, 1996. GRISI, L.; MASSARD, C.L.; MOYA, G.E.; PEREIRA, J.B. Impacto econ?mico das principais ectoparasitoses em bovinos no Brasil. Hora Veterin?ria, v 2, p. 8-10, 2002. GUIMAR?ES, J.H; PAPAVERO, N.; PRADO, A.P. As mi?ases da Regi?o Neotropical. ReVevista Brasileira de Zoologia, v 1: 239-416, 1983. GUIMAR?ES, J. H.; PAPAVERO, N. Generalities about myiasis in the Neotropical Region. In: myiasis in Man and Animals in the Neotropical Region ? Bib ? Liographic Database. S?o Paulo: Pl?iade, a. 308p. Cap. 1, p. 16, 1998 a. HAN, H. S.; NOLI, C.; CENA, T. Efficacy and duration of action of oral fluralaner and spot?on moxidectin/imidacloprid in cats infested with Lynxacarus radovskyi. Veterinary dermatology, v.27, s.6, p.474-e127, 2016. HARWOOD, F.R; JAMES, M.T. In: Entomology in Human and Animal Health, 7th edition. Macmillan. New York, pp. 313-315, 1979. HOPE, F.W. On insects and their larvae occasionally found in the human body. Transactions of the Entomological Society of London, v. 2, pp. 256-271, 1840. HUNTER, J. S. et al. Evaluation of the curative and preventive efficacy of a single oral administration of afoxolaner against cat flea Ctenocephalides felis infestations on dogs. Veterinary Parasitology, v.201, p.207-211, 2014. IRWON, P.J.; JEFFERIES, R. Artropod- transmitted diseases of companion animals in Southeast Asia. Trends in Parasitology, v 1, 27-34. 2004. KARADZOVSKA, D.; CHAPPELL, K.; COBLE, S. A randomized, controlled field study to assess the efficacy and safety of lotilaner flavored chewable tablets (CredelioTM) in eliminating fleas in client-owned dogs in the USA. Parasites & Vectors, v.10, p.528, 2017. KHAN, D.G. Myiasis secondary to Dermatobia hominis (human botfly) presenting as a long-standingbreast mass. Archives of Pathology & Laboratory Medicine online, 123: 829-831, 1999. KILP, S.; RAMIREZ, D.; ALLAN, J. Comparative pharmacokinetics of fluralaner in dogs and cats following single topical or intravenous administration. Parasites & Vectors, v.9, p.296, 2016. KUNKLE, B. et al. Assessment of the efficacy of orally administered afoxolaner against Rhipicephalus sanguineus sensu lato. Veterinary parasitology, v.20, s.3-4, p.226-228, 2014b. LIEBERT.P, S; MADDEN.R, C. Human botfly larva in a child?s scalp. Journal Pediatric Surgury, 39: 490-491, 2004. LOBO, G.; ZELED?N, R. Algunos aspectos sobre l? populaci?n de Dermatobia hominis (L.jr.)(Diptera:Cuterebridae). Turrialba, v. 34(I):1-8.1984. MACHADO, M. A. et al. Efficacy of afoxolaner in the treatment of otodectic mange in naturally infested cats. Veterinary parasitology, v.256, p.29-31, 2018. MANDELL, G.; BENNET, J.; DOLIN, R. Chapter 293: Myiasis and tungiasis. In: Principles and Practice of infectious Diseases, 6th edn. 2004. Available at: http://o-www.mdconsult.com.innopac.library.unr.edu:80/das/book/body/924153734/695200800/1259/2373.html#4-ui.o-Bo-44306643-4..50296-8-cesecI_9I03, acessado 10 de maio de 2019. MARCHIONDO, A.A.; HOLDSWORTH, P.A.; FOURIE L.J.; RUGG D.; HELLMANN, K.; SNYDER, D.E.; DRYDEN, M.W. Guidelines for evaluating the efficacy of parasiticides for the treatment, prevention and control of flea and tick infestations on dogs and cats. 2nd ed. World Association for the Advancement of Veterinary Parasitology. Vet. Parasitol, 194(1):84-97, 2013. MARQUES, D.C. Ectoparasitos. In: Cria??o de bovinos. 7? ed. Belo Horizonte: CVP, 374pp, 2003. MARTY, F. M; WHITESIDE, K. R. Images in clinical medicine. Myiasis due to Dermatobia hominis (human botfly). The new England Journal Of Medicine, p.352: e2I, 2005. MCGRAW, T.; TURIANSKY, G. Cutaneous myiasis. Journal of the American Academy of Dermatology, v. 58: 907-926, 2008. MCTIER, T. L. et al. Discovery of sarolaner: a novel, orally administered, broad-spectrum, isoxazoline ectoparasiticide for dogs. Veterinary parasitology, v.222, p.3-11, 2016. MCTIER, T. L. et al. The efficacy of a novel topical formulation of selamectin plus sarolaner (Revolution Plus/ Stronghold Plus) in preventing the development of Dirofilaria immitis in cats. Veterinary Parasitology, v.270, p.56-62, 2019. MEDEIROS, D.C.; BAPTISTA, M.N.; BORJA, G.E.M. Frequ?ncia populacional de Dermatobia hominis (Linnaeus Jr., 1781) (Diptera: Cuterebridae) e sua correla??o com vari?veis clim?ticas, no sudeste do Brasil. Brazilian Journal Veterinary Research and Animal Science. S?o Paulo, v.52, n.4, p.350-355, 2015. MENDES ? DE- ALMEIDA, F.; LABARTHE, N.; GUERRERO,J . et al., Cochliomya hominivorax myiasis in a colony of mstray cats (felis catus Linnaeus, 1758) in Rio de Janeiro, Rj. Veterinary Parasitology, v. 146: 376-378, 2007. MOYA BORJA, G. E. Estudios sobre la biologia, morfologia y esterilizaci?n del t?rsalo, Dermatobia hominis (L.jr.). M.S.c. Thesis, IIca, Yurrialba, Costa Rica, p. 63, 1966. MOYA BORJA, G.E. Retrospectiva da dermatobiose ? biologia e epidemiologia da Dermatobia hominis. Anais da XI jornada cient?fica da UFRRJ, Campo Grande.p. 303-314, jul./ 1979. MOYA BORJA, G.E. Erradica??o ou manejo integrado das mi?ases neotropicais das Am?ricas? Pesquisa Veterin?ria Brasileira, v. 32:131-138, 2003. MURPHY, M. et al. Laboratory evaluations of the immediate and sustained efficacy of lotilaner (Credelio?) against four common species of ticks affecting dogs in North America. Parasites & vectors, v.10, s.1, p.523, 2017. NOUTIS,C.; MILLIKAN, L. E. Myiasis. Dermatology Clinical, v.12:81-83,1994. OZOE, Y.; ASAHI, M.; OZOE, F. The antiparasitic isoxazoline A1443 is a potent blocker of insect ligand-gated chloride channels. Biochemical Biophysical Res Commun, v.391, p.744-749, 2010. OLIVEIRA, P.C. et al. Efficacy of spinosad on the treatment of myiasis caused by Cochliomyia hominivorax (Diptera: Calliphoridae) in dogs. Veterinary Parasitology, v.258, p.53-56, 2018. PALLAI. L.; HODGE.J.;FISHMAN. S,J.; MILLIKAN. L,E.; PHELPS. R,G.; Case report: Myiasis- the botfly boil. The American journal Of The Medical Scienses, 303: 245-248.1992. PEREIRA. M,C, T.; LEITE, V.H.R.; LEITE, A.C.R. Experimental skin lesions from larvae of the bot fly Dermatobia hominis. Medical and Veterinary Entomology, v. 15: 22-27, 2001. PINOS, V.H.; ORTIZ PRADO, E.; BERMEO, C.; LE?N, J.; ARMIJOS, L.; ALMEIDA, E. Case Report: A unique case of facial burn superinfected with Dermatobia hominis larvae resulting in a bilateral enucleation of the eyes.Tropical . Tropical Doctor. Vol. 44 (4), pp. 235-237, 2014. RIBEIRO, B.C.C.; SANAVRIA, A.; MORAES, A. C.; REIS, T. P.; SOUZA, F.S. Ocorr?ncia de mi?ases por Dermatobia hominis (Cuterebridae) em c?es procedentes da ?rea rural do Estado do Rio de Janeiro em Dezembro de 2000. Anais da XI jornada de Inicia??o Cientifica da UFRRJ. V. 11, p. 141-144, 2001. ROBBINS, K.; KHACHEMOUNE, A.C.W.S. Review: Cutaneous myiasis: a review of the common types of myiasis. International Journal of Dermatology, v. 49, pp. 1092-1098, 2010. RONCALLI, R.A. The biology and control of Dermatobia hominis, the tropical warble-fly of latin America. Preventive Veterinary Medicine, 2: 569-678,1984. ROOSJE, P.J.; HENDRIKY, W.M.L.; WISSELINK, M. A. & WILLEMSE, T. A case of a Dermatobia hominis infection in a dog in the Netherland. Veterinary Dermatology, vol 3, n?4/5, pp. 183-185, 1992. SANAVRIA, A.; BARBOSA, C.G.; BEZERRA, E.S.; MORAIS, M.C.; GIUPPONI, P. . Distribui??o de larvas de Dermatobia hominis (Linnaeus Jr.; 1781)(Diptera: Cuterebridae) em peles de bovinos. Parasitologia Latinoamericana, v. 57, p. 21-24, 2002. SCOTT, F. et al. Efficacy of sarolaner (Simparica?) against induced infestations of Amblyomma cajennense on dogs. Parasites & Vectors, v.10, s.1, p.390, 2017. SHAW, S.E.; DAY, M.J. Arthropod-borne infectious Diseases of the dog and cat. Manson Publishing, pp.9-10, London, 2005. SIX, R.H. et al. Efficacy of sarolaner, a novel oral isoxazoline, against two common mite infestations in dogs: Demodex spp. and Otodectes cynotis . Veterinary Parasitology, v. 222, p.62-69, 2016a. SIX, R.H. et al. Evaluation of the speed of kill of sarolaner (Simparica?) against induced infestations of three species of ticks (Amblyomma maculatum, Ixodes scapularis, Ixodes ricinus) on dogs. Veterinary Parasitology, v.222, p.37-42, 2016b. SIX, R.H. et al. Efficacy of a novel oral formulation of sarolaner (Simparica?) against five common tick species infesting dogs in the United States. Veterinary Parasitology, v.222, p.28?32, 2016d. SOJKA, P.A. Therapeutic review?isoxazolines. Journal of Exotic Pet Medicine, v.27, p. 118-122, 2018. TAENZLER, J. et al. Onset of activity of fluralaner (BRAVECTO?) against Ctenocephalides felis on dogs. Parasites & Vectors, v.7, s.1, p.567, 2014. TAENZLER, J. et al. Efficacy of fluralaner against Otodectes cynotis infestations in dogs and cats. Parasites & Vectors, v.10, s.1, p.30, 2017. TOUTAIN, C. E.; SEEWALD, W.; JUNG, M. The intravenous and oral pharmacokinetics of lotilaner in dogs. Parasites & Vectors, v.10, s.1, p.522, 2017. URQUHART, G.M.; ARMOUR, J.; DUNCAN, J. L.; DUNN, A. M.; JENNINGS, F. W. Entomologia Veterin?ria. In: URQUHART, G.M.; ARMOUR, J.; DUNCAN, J. L.; DUNN, A. M.; JENNINGS, F. W. Parasitologia Veterin?ria. Rio de Janeiro: Guanabara, p. 175-176, 1990. VARLOUD, M.; FOURIE, J. J. Onset of efficacy and residual speed of kill over one month of a topical dinotefuran-permethrin-pyriproxyfen combination (Vectra? 3D) against the adult cat flea (Ctenocephalides felis felis) on dogs. Veterinary Parasitology, v.211, s.1-2, p.89-92, 2015. VATTA, A. F. et al. Efficacy of a new spot-on formulation of selamectin plus sarolaner for cats against adult Ctenocephalides felis, flea egg production and adult flea emergence. Veterinary parasitology, v.238, S22-S26, 2017. VATTA, A. F. et al. Comparative efficacy of topical treatments with Revolution Plus (selamectin and sarolaner) and Bravecto for cats (fluralaner) against Ixodes scapularis ticks on cats. Veterinary parasitology, v.270, S58-S63, 2019b. VILLALOBOS. G.; VEGA - MEMIJE. M, E.; MARAVILLA. P.; MARTINEZ- HERNANDEZ, F. Review: Myiasis caused by Dermatobia hominis: countries with increased risk for travelers going to neotropic areas. International Journal of Dermatology, v. 55, p. 1060-1068, 2016. VERANI, S.; TASSINARI, D.;ELLERI, D, et al. A case of furuncular myiasis associated with systemic inflammation. International Journal for Parasitology, v. 56:330-333, 2007. WALTHER, F.M. et al. Safety of fluralaner, a novel systemic antiparasitic drug, in MDR1 (-/-) Collies after oral administration. Parasites & Vectors, v.7, s.86, 2014a. WEBER, T.; SELZER, P.M. Isoxazolines: A novel chemotype higly effective on ectoparasites. Chemmedchem Minireviews, v. 11, p.270-276, 2016. WILLWMSE, T. Doen?as Parasit?rias. In: WILLEMSE, T. Dermatologia cl?nica de c?es e gatos. S?o Paulo: Manole, p. 27-39, 1998. WISMER, T.; MEANS, C. Toxicology of newer insecticides in small animals. Veterinary of North America: Small Animal Practice, v.42, s.2, 2012. WOODS, D.J.; MCTIER T.L.; DEROSA, A.A. Comparison of the Anti-ectoparasite and Anti-endoparasite Therapies and Control Strategies. In: Ectoparasites ? Drug Discovery Against Moving Targets, v.8, p.3-24, 2018. WOODS, D.J.; MCTIER, T.L. Discovery, development and commercialization of sarolaner (Simparica?), a novel oral isozaxoline ectoparasiticide for dogs. In: Ectoparasites ? Drug Discovery Against Moving Targets, v.8, p. 295-318, 2018. ZAKSON-AIKEN, M. et al. Systemic activity of the avermectins against the cat flea, Ctenocephalides felis (Siphonaptera: Pulicidae). Journal of the Medical Entomology, v.38, n.4, p.576-580, 2000.
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Federal Rural do Rio de Janeiro
dc.publisher.program.fl_str_mv Programa de P?s-Gradua??o em Medicina Veterin?ria (Patologia e Ci?ncias Cl?nicas)
dc.publisher.initials.fl_str_mv UFRRJ
dc.publisher.country.fl_str_mv Brasil
dc.publisher.department.fl_str_mv Instituto de Veterin?ria
publisher.none.fl_str_mv Universidade Federal Rural do Rio de Janeiro
dc.source.none.fl_str_mv reponame:Biblioteca Digital de Teses e Dissertações da UFRRJ
instname:Universidade Federal Rural do Rio de Janeiro (UFRRJ)
instacron:UFRRJ
instname_str Universidade Federal Rural do Rio de Janeiro (UFRRJ)
instacron_str UFRRJ
institution UFRRJ
reponame_str Biblioteca Digital de Teses e Dissertações da UFRRJ
collection Biblioteca Digital de Teses e Dissertações da UFRRJ
bitstream.url.fl_str_mv http://localhost:8080/tede/bitstream/jspui/6319/4/2020+-+Paula+Azevedo+Andriotti.Pdf.jpg
http://localhost:8080/tede/bitstream/jspui/6319/3/2020+-+Paula+Azevedo+Andriotti.Pdf.txt
http://localhost:8080/tede/bitstream/jspui/6319/2/2020+-+Paula+Azevedo+Andriotti.Pdf
http://localhost:8080/tede/bitstream/jspui/6319/1/license.txt
bitstream.checksum.fl_str_mv cc73c4c239a4c332d642ba1e7c7a9fb2
5a1172fd66775aa26a5c4d5196a24fe6
f818e8478a2807e3bd8e4a2817234bc3
7b5ba3d2445355f386edab96125d42b7
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
MD5
repository.name.fl_str_mv Biblioteca Digital de Teses e Dissertações da UFRRJ - Universidade Federal Rural do Rio de Janeiro (UFRRJ)
repository.mail.fl_str_mv bibliot@ufrrj.br||bibliot@ufrrj.br
_version_ 1797220386666971136

Registros relacionados