Desenvolvimento de metodologias eletroquímicas para monitoramento ambiental da rifampicina e sua eletrodegradação pela geração de agentes oxidantes in situ

• Ano de defesa: 2010
• Autor(a) principal: Santos, Renê Humberto Tavares
• Orientador(a): Arguelho, Maria de Lara Palmeira de Macedo
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de Sergipe
• Programa de Pós-Graduação: Pós-Graduação em Química
• País: BR
• Palavras-chave em Português: Rifampicina; Quitosana; Eletrodegradação ADEs
• Palavras-chave em Inglês: Rifampicin; Chitosan; Electrodegradation DSA
• Área do conhecimento CNPq: CNPQ::CIENCIAS EXATAS E DA TERRA::QUIMICA
• Link de acesso: https://ri.ufs.br/handle/riufs/6131

The drugs are considered pollutant emergent, a time that its presence in aquatic environments is each bigger time. This research has as objective to develop electrochemical methodologies that allow to monitor and to degrade the rifampicin in water of public supplying. In the stage of monitor a voltammetric method was developed using a biosensor of chitosan for rifampicin analysis. Parallel to this study was development and optimized a electrodegradation method using electrode of the type Dimensionally Stable Anodes DSA® (Ti/RuO2 - TiO2). The voltammetric behavior of the rifampicin in the biosensor of chitosan using itself it technique of differential pulse voltammetry on indicates the presence of a peak of irreversible oxidation in 0,492 V (versus Ag/AgCl) corresponding the electronic transference of two electrons for molecule. The study of the effect of the speed of sweepings and pH of the way they indicate to be about a electrodic process with diffusional and dependent control of pH. The voltammetric method of determination of the rifampicin presents a recovery of 110% for 1,0 10-5 mol.L-1. From the experiments of electrodegradation of the rifampicin under electrodes DSA® it was evaluated influence of the chain density, getting as excellent value 120 mA cm-2. For the different assays in pHs, it was possible to observe that the half reacionais with pHs 8 and 3 favor the electrolysis of the rifampicin for this type of reactor in NaCl as electrolyte has supported with electrodegradation of 100% of organic molecules of the rifampicina in only 72s and 84s in these half reationais. Being that in only 48s the molecule of the rifampicin total is degraded, in turn, its by-products have a time of 24 electrodegradation of and 36s. The application in water of supplying with accompaniment of the loss of color was made through spectrophotometry in the region of UV-Visible, in =370 nm. It approximately had a complete removal of the color and total reduction of the absorbance in the electrodegradation of the rifampicin in 96 and 84s of electrolysis in the two studied ways, pH 3 and 8 respectively.