Síntese regioespecífica de 1H-pirazolilquinolinas trifluormetil substituídas

Detalhes bibliográficos
Ano de defesa: 2004
Autor(a) principal: Cechinel, Cleber André lattes
Orientador(a): Bonacorso, Helio Gauze lattes
Banca de defesa: Dacol, Ionara Irion, Martins, Marcos Antonio Pinto
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Federal de Santa Maria
Centro de Ciências Naturais e Exatas
Programa de Pós-Graduação: Programa de Pós-Graduação em Química
Departamento: Química
País: Brasil
Palavras-chave em Português:
Heterociclos
Quinolinas
Pirazóis
Trifluormetilados
Área do conhecimento CNPq:
CNPQ::CIENCIAS EXATAS E DA TERRA::QUIMICA
Link de acesso: http://repositorio.ufsm.br/handle/1/27372
Resumo: This work describes the synthesis of a serie of 4-(3-alkyl(aryl)-5-trifluoromethyl-1Hpyrazol- 1-yl)-7-chloroquinolines (6), from the cyclondensation reactions of 1,1,1-trifluoro- 4-methoxy-3-buten-2-ones (4) and 7-chloro-4-hydrazinoquinoline, with isolation of the intermediary pyrazolines 4-[3-alkyl(aryl)-5-trifluoromethyl-5-hydroxy-4,5-dihydro-1Hpirazol- 1-yl]-7-chloroquinolines (5). [...]
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spelling 2022-12-16T13:40:19Z2022-12-16T13:40:19Z2004-07-27http://repositorio.ufsm.br/handle/1/27372This work describes the synthesis of a serie of 4-(3-alkyl(aryl)-5-trifluoromethyl-1Hpyrazol- 1-yl)-7-chloroquinolines (6), from the cyclondensation reactions of 1,1,1-trifluoro- 4-methoxy-3-buten-2-ones (4) and 7-chloro-4-hydrazinoquinoline, with isolation of the intermediary pyrazolines 4-[3-alkyl(aryl)-5-trifluoromethyl-5-hydroxy-4,5-dihydro-1Hpirazol- 1-yl]-7-chloroquinolines (5). [...]A presente dissertação descreve a síntese de uma série de 4-[3-alquil(aril)-5- trifluormetil-1H-pirazol-1-il]-7-cloroquinolinas (6), a partir de reações de ciclocondensação entre 1,1,1-trifluor-4-metoxi-3-buten-2-onas (4) e 7-cloro-4- hidrazinoquinolina, com isolamento das pirazolinas intermediárias 4-[3-alquil(aril)-5- trifluormetil-5-hidroxi-4,5-diidro-1H-pirazol-1-il]-7-cloroquinolinas (5). [...]Fundação de Apoio Tecnologia e Ciência - FATECporUniversidade Federal de Santa MariaCentro de Ciências Naturais e ExatasPrograma de Pós-Graduação em QuímicaUFSMBrasilQuímicaAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessHeterociclosQuinolinasPirazóisTrifluormetiladosCNPQ::CIENCIAS EXATAS E DA TERRA::QUIMICASíntese regioespecífica de 1H-pirazolilquinolinas trifluormetil substituídasRegiospecific synthesis of 1H-pyrazolylquinolines trifluoromethyl substituteinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisBonacorso, Helio Gauzehttp://lattes.cnpq.br/7275608974248322Dacol, Ionara IrionMartins, Marcos Antonio Pintohttp://lattes.cnpq.br/2071328479519741Cechinel, Cleber André10060000000060060060060060006c852ad-d805-43c3-99d6-93a6a86f507cf9f31f96-f33b-4c6a-8636-a85c23974aadda58e2e8-43a8-40a3-8fb9-544a6f59d5ed5450ad79-4703-4a15-93a4-86f80794d585reponame:Biblioteca Digital de Teses e Dissertações do UFSMinstname:Universidade Federal de Santa Maria (UFSM)instacron:UFSMORIGINALDIS_PPGQUÍMICA_2004_CECHINEL_CLEBER.pdfDIS_PPGQUÍMICA_2004_CECHINEL_CLEBER.pdfDissertação de Mestradoapplication/pdf1206733http://repositorio.ufsm.br/bitstream/1/27372/1/DIS_PPGQU%c3%8dMICA_2004_CECHINEL_CLEBER.pdfa7195dc7467690d5864a07ddf8b25d05MD51CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8805http://repositorio.ufsm.br/bitstream/1/27372/2/license_rdf4460e5956bc1d1639be9ae6146a50347MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-81956http://repositorio.ufsm.br/bitstream/1/27372/3/license.txt2f0571ecee68693bd5cd3f17c1e075dfMD531/273722022-12-16 10:40:19.732oai:repositorio.ufsm.br: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 Digital de Teses e Dissertaçõeshttps://repositorio.ufsm.br/ONGhttps://repositorio.ufsm.br/oai/requestatendimento.sib@ufsm.br||tedebc@gmail.comopendoar:2022-12-16T13:40:19Biblioteca Digital de Teses e Dissertações do UFSM - Universidade Federal de Santa Maria (UFSM)false
dc.title.por.fl_str_mv Síntese regioespecífica de 1H-pirazolilquinolinas trifluormetil substituídas
dc.title.alternative.eng.fl_str_mv Regiospecific synthesis of 1H-pyrazolylquinolines trifluoromethyl substitute
title Síntese regioespecífica de 1H-pirazolilquinolinas trifluormetil substituídas
spellingShingle Síntese regioespecífica de 1H-pirazolilquinolinas trifluormetil substituídas
Cechinel, Cleber André
Heterociclos
Quinolinas
Pirazóis
Trifluormetilados
CNPQ::CIENCIAS EXATAS E DA TERRA::QUIMICA
title_short Síntese regioespecífica de 1H-pirazolilquinolinas trifluormetil substituídas
title_full Síntese regioespecífica de 1H-pirazolilquinolinas trifluormetil substituídas
title_fullStr Síntese regioespecífica de 1H-pirazolilquinolinas trifluormetil substituídas
title_full_unstemmed Síntese regioespecífica de 1H-pirazolilquinolinas trifluormetil substituídas
title_sort Síntese regioespecífica de 1H-pirazolilquinolinas trifluormetil substituídas
author Cechinel, Cleber André
author_facet Cechinel, Cleber André
author_role author
dc.contributor.advisor1.fl_str_mv Bonacorso, Helio Gauze
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/7275608974248322
dc.contributor.referee1.fl_str_mv Dacol, Ionara Irion
dc.contributor.referee2.fl_str_mv Martins, Marcos Antonio Pinto
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/2071328479519741
dc.contributor.author.fl_str_mv Cechinel, Cleber André
contributor_str_mv Bonacorso, Helio Gauze
Dacol, Ionara Irion
Martins, Marcos Antonio Pinto
dc.subject.por.fl_str_mv Heterociclos
Quinolinas
Pirazóis
Trifluormetilados
topic Heterociclos
Quinolinas
Pirazóis
Trifluormetilados
CNPQ::CIENCIAS EXATAS E DA TERRA::QUIMICA
dc.subject.cnpq.fl_str_mv CNPQ::CIENCIAS EXATAS E DA TERRA::QUIMICA
description This work describes the synthesis of a serie of 4-(3-alkyl(aryl)-5-trifluoromethyl-1Hpyrazol- 1-yl)-7-chloroquinolines (6), from the cyclondensation reactions of 1,1,1-trifluoro- 4-methoxy-3-buten-2-ones (4) and 7-chloro-4-hydrazinoquinoline, with isolation of the intermediary pyrazolines 4-[3-alkyl(aryl)-5-trifluoromethyl-5-hydroxy-4,5-dihydro-1Hpirazol- 1-yl]-7-chloroquinolines (5). [...]
publishDate 2004
dc.date.issued.fl_str_mv 2004-07-27
dc.date.accessioned.fl_str_mv 2022-12-16T13:40:19Z
dc.date.available.fl_str_mv 2022-12-16T13:40:19Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufsm.br/handle/1/27372
url http://repositorio.ufsm.br/handle/1/27372
dc.language.iso.fl_str_mv por
language por
dc.relation.cnpq.fl_str_mv 100600000000
dc.relation.confidence.fl_str_mv 600
600
600
600
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5450ad79-4703-4a15-93a4-86f80794d585
dc.rights.driver.fl_str_mv Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Universidade Federal de Santa Maria
Centro de Ciências Naturais e Exatas
dc.publisher.program.fl_str_mv Programa de Pós-Graduação em Química
dc.publisher.initials.fl_str_mv UFSM
dc.publisher.country.fl_str_mv Brasil
dc.publisher.department.fl_str_mv Química
publisher.none.fl_str_mv Universidade Federal de Santa Maria
Centro de Ciências Naturais e Exatas
dc.source.none.fl_str_mv reponame:Biblioteca Digital de Teses e Dissertações do UFSM
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institution UFSM
reponame_str Biblioteca Digital de Teses e Dissertações do UFSM
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