Evaluation of occupational exposures in Endoscopic Retrograde Cholangiopancreatography using Monte Carlo simulation

Detalhes bibliográficos
Ano de defesa: 2020
Autor(a) principal: Souza, Lucas Wilian Gonçalves de lattes
Orientador(a): Neves, Lucio Pereira lattes
Banca de defesa: Milagre, Selma Terezinha lattes, Caldas, Linda Viola Ehlin lattes
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: eng
Instituição de defesa: Universidade Federal de Uberlândia
Programa de Pós-Graduação: Programa de Pós-graduação em Engenharia Biomédica
Departamento: Não Informado pela instituição
País: Brasil
Palavras-chave em Português:
Área do conhecimento CNPq:
Link de acesso: https://repositorio.ufu.br/handle/123456789/29138
http://doi.org/10.14393/ufu.di.2020.295
Resumo: The contemporary life style and the aging of world population have set a favorable scenario to the increase of hepatobiliary and pancreatic diseases. The Endoscopic Retrograde Cholangiopancreatography (ERCP) is one of the main medical techniques employed to diagnose and treat those diseases. ERCP is a fluoroscopy guided procedure, therefore it exposes patient and medical staff to ionizing radiation. This exposure may lead to tissue reactions and cancer later in life. The objective of this work was to apply Monte Carlo (MC) simulation to evaluate patient and staff radiation exposure during ERCP procedures. The simulated scenario reproduced a typical ERCP room equipped with an over-couch x-ray system. MASH3 and FASH3 virtual anthropomorphic phantoms were utilised to represent the patient, the physician and the assistant physician. The patient was placed in prone position on the table. The staff wore 0.5 mm Pb apron, thyroid collar and eyewear. The fluoroscopic parameters were tube voltage of 70, 80, 90, 100 and 110 kVp; the Field of View (FOV) sizes were 15×15 cm2, 17×17 cm2, 22×22 cm2, 25×25 cm2, 31×31 cm2 and 38×38 cm2. The x-ray spectra were simulated in SRS78 software and the Monte Carlo simulations were implemented in the Monte Carlo N-Particle eXtended (MCNPX) (version 2.7.0) code. For a given tube voltage, the results show an increase of patient conversion coefficients for effective dose CC[E] values for FOV sizes increments until the irradiated area suppressed patient area, then for larger FOV sizes, the CC[E] values decreased. For a defined FOV size, the patient CC[E] values raised as the tube voltage was increased. Concerning the staff, the CC[E] values increased for elevated tube voltages, given a fixed FOV size. Their CC[E] values also raised when the tube voltage was unchanged but the FOV sizes were expanded. The effective dose calculated from the mean CC[E] values and Dose Area Product (DAP) from the literature are in agreement with previous works. The estimated conversion coefficients for equivalent dose CC[HT] values are also consistent with the literature. This work presents the first results of a greater project focused on the radiation protection at an university hospital.
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spelling 2020-04-07T11:32:35Z2020-04-07T11:32:35Z2020-03-05SOUZA, Lucas Wilian Gonçalves de. Evaluation of occupational exposures in Endoscopic Retrograde Cholangiopancreatography using Monte Carlo simulation. 2020. 93 f.(Mestrado em Engenharia Biomédica) - Universidade Federal de Uberlândia, Uberlândia, 2020. Disponível em: http://doi.org/10.14393/ufu.di.2020.295.https://repositorio.ufu.br/handle/123456789/29138http://doi.org/10.14393/ufu.di.2020.295The contemporary life style and the aging of world population have set a favorable scenario to the increase of hepatobiliary and pancreatic diseases. The Endoscopic Retrograde Cholangiopancreatography (ERCP) is one of the main medical techniques employed to diagnose and treat those diseases. ERCP is a fluoroscopy guided procedure, therefore it exposes patient and medical staff to ionizing radiation. This exposure may lead to tissue reactions and cancer later in life. The objective of this work was to apply Monte Carlo (MC) simulation to evaluate patient and staff radiation exposure during ERCP procedures. The simulated scenario reproduced a typical ERCP room equipped with an over-couch x-ray system. MASH3 and FASH3 virtual anthropomorphic phantoms were utilised to represent the patient, the physician and the assistant physician. The patient was placed in prone position on the table. The staff wore 0.5 mm Pb apron, thyroid collar and eyewear. The fluoroscopic parameters were tube voltage of 70, 80, 90, 100 and 110 kVp; the Field of View (FOV) sizes were 15×15 cm2, 17×17 cm2, 22×22 cm2, 25×25 cm2, 31×31 cm2 and 38×38 cm2. The x-ray spectra were simulated in SRS78 software and the Monte Carlo simulations were implemented in the Monte Carlo N-Particle eXtended (MCNPX) (version 2.7.0) code. For a given tube voltage, the results show an increase of patient conversion coefficients for effective dose CC[E] values for FOV sizes increments until the irradiated area suppressed patient area, then for larger FOV sizes, the CC[E] values decreased. For a defined FOV size, the patient CC[E] values raised as the tube voltage was increased. Concerning the staff, the CC[E] values increased for elevated tube voltages, given a fixed FOV size. Their CC[E] values also raised when the tube voltage was unchanged but the FOV sizes were expanded. The effective dose calculated from the mean CC[E] values and Dose Area Product (DAP) from the literature are in agreement with previous works. The estimated conversion coefficients for equivalent dose CC[HT] values are also consistent with the literature. This work presents the first results of a greater project focused on the radiation protection at an university hospital.O modo de vida contemporâneo em conjunto com o envelhecimento da população mundial criam um cenário favorável ao aumento das doenças hepatobiliárias e pancreáticas. A Colangiopancreatografia Endoscópica Retrógrada (ERCP) é uma das principais técnicas médicas aplicadas no diagnóstico e tratamento dessas doenças. A ERCP é um procedimento guiado por fluoroscopia, portanto ela expõe paciente e profissionais à radiação ionizante. Essa exposição pode provocar reações teciduais e câncer tardio. O objetivo desse trabalho foi aplicar simulações de Monte Carlo (MC) para avaliar a exposição à radiação de pacientes e profissionais durante procedimentos de ERCP. O cenário simulado reproduziu uma sala típica de ERCP equipada com um sistema de raios-x com tubo acima da mesa. Os simuladores virtuais antropomórficos MASH3 e FASH3 foram utilizados para representar paciente, médico e médico assistente. O paciente foi simulado na posição prona sobre a mesa. Os profissionais utilizaram avental com equivalência de 0.5 mm de Pb, protetor de tireoide e óculos plumbífero. Os parâmetros fluoroscópicos foram tensão do tubo de 70, 80, 90, 100 e 110 kVp; tamanho de campo irradiado de 15×15 cm2, 17×17 cm2, 22×22 cm2, 25×25 cm2, 31×31 cm2 e 38×38 cm2. Os espectros de raios-x foram simulados no programa SRS 78 e as simulações de Monte Carlo foram implementadas no código Monte Carlo N-Particle eXtenteded (MCNPX) (versão 2.7.0). Os resultados mostram que, para uma tensão do tubo, os coeficientes de conversão para dose efetiva CC[E] do paciente aumentaram até que a área irradiada se tornou maior do que a área do paciente que deveria ter sido irradiada. Para um campo fixo, os CC[E] do paciente aumentaram à medida que a tensão do tubo foi aumentada. Considerando os profissionais, os valores de CC[E] também aumentaram quando o campo aumentou, mas a tensão do tubo foi inalterada. Os valores de CC[E], para um tamanho do campo fixo, aumentaram quando a tensão do tubo foi elevada. As doses efetivas estimadas com os valores médios dos CC[E] e valores de Produto Dose Área (DAP) encontrados na literatura estão de acordo com os valores de trabalhos anteriores. Os valores dos coeficientes de conversão para dose equivalente CC[HT] também estão de acordo com a literatura. Este trabalho apresenta os primeiros resultados de um projeto maior que foca na proteção radiológica de um hospital universitário.CNPq - Conselho Nacional de Desenvolvimento Científico e TecnológicoFAPEMIG - Fundação de Amparo a Pesquisa do Estado de Minas GeraisDissertação (Mestrado)engUniversidade Federal de UberlândiaPrograma de Pós-graduação em Engenharia BiomédicaBrasilhttp://creativecommons.org/licenses/by-nc/3.0/us/info:eu-repo/semantics/openAccessCNPQ::ENGENHARIAS::ENGENHARIA BIOMEDICAERCPIonizing RadiationMonte Carlo SimulationDosimetryRadiation ProtectionRadiação IonizanteSimulação de Monte CarloDosimetriaProteção RadiológicaEvaluation of occupational exposures in Endoscopic Retrograde Cholangiopancreatography using Monte Carlo simulationAvaliação das exposições ocupacionais em Colangiopancreatografia Retrógrada Endoscópica utilizando Simulação de Monte Carloinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisPerini, Ana Paulahttp://lattes.cnpq.br/4681700210308237Neves, Lucio Pereirahttp://lattes.cnpq.br/9028304261745922Milagre, Selma Terezinhahttp://lattes.cnpq.br/4980687835840176Caldas, Linda Viola Ehlinhttp://lattes.cnpq.br/2032000100824080http://lattes.cnpq.br/2802586397251897Souza, Lucas Wilian Gonçalves de9371706972reponame:Repositório Institucional da UFUinstname:Universidade Federal de Uberlândia (UFU)instacron:UFUORIGINALEvaluationERCP.pdfEvaluationERCP.pdfapplication/pdf5404638https://repositorio.ufu.br/bitstream/123456789/29138/1/EvaluationERCP.pdf9726af398a63e7004e5fecf7ce158ad0MD51CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8920https://repositorio.ufu.br/bitstream/123456789/29138/2/license_rdfdd65805249d68ea862568f59102935acMD52LICENSElicense.txtlicense.txttext/plain; charset=utf-81792https://repositorio.ufu.br/bitstream/123456789/29138/3/license.txt48ded82ce41b8d2426af12aed6b3cbf3MD53TEXTEvaluationERCP.pdf.txtEvaluationERCP.pdf.txtExtracted texttext/plain201191https://repositorio.ufu.br/bitstream/123456789/29138/4/EvaluationERCP.pdf.txta4e667beedb3ae9cb2fe96e6cad9728aMD54THUMBNAILEvaluationERCP.pdf.jpgEvaluationERCP.pdf.jpgGenerated Thumbnailimage/jpeg1368https://repositorio.ufu.br/bitstream/123456789/29138/5/EvaluationERCP.pdf.jpga351698b9ce6f678bc3bd359c5093eecMD55123456789/291382020-04-08 03:12:00.921oai:repositorio.ufu.br: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Repositório InstitucionalONGhttp://repositorio.ufu.br/oai/requestdiinf@dirbi.ufu.bropendoar:2020-04-08T06:12Repositório Institucional da UFU - Universidade Federal de Uberlândia (UFU)false
dc.title.pt_BR.fl_str_mv Evaluation of occupational exposures in Endoscopic Retrograde Cholangiopancreatography using Monte Carlo simulation
dc.title.alternative.pt_BR.fl_str_mv Avaliação das exposições ocupacionais em Colangiopancreatografia Retrógrada Endoscópica utilizando Simulação de Monte Carlo
title Evaluation of occupational exposures in Endoscopic Retrograde Cholangiopancreatography using Monte Carlo simulation
spellingShingle Evaluation of occupational exposures in Endoscopic Retrograde Cholangiopancreatography using Monte Carlo simulation
Souza, Lucas Wilian Gonçalves de
CNPQ::ENGENHARIAS::ENGENHARIA BIOMEDICA
ERCP
Ionizing Radiation
Monte Carlo Simulation
Dosimetry
Radiation Protection
Radiação Ionizante
Simulação de Monte Carlo
Dosimetria
Proteção Radiológica
title_short Evaluation of occupational exposures in Endoscopic Retrograde Cholangiopancreatography using Monte Carlo simulation
title_full Evaluation of occupational exposures in Endoscopic Retrograde Cholangiopancreatography using Monte Carlo simulation
title_fullStr Evaluation of occupational exposures in Endoscopic Retrograde Cholangiopancreatography using Monte Carlo simulation
title_full_unstemmed Evaluation of occupational exposures in Endoscopic Retrograde Cholangiopancreatography using Monte Carlo simulation
title_sort Evaluation of occupational exposures in Endoscopic Retrograde Cholangiopancreatography using Monte Carlo simulation
author Souza, Lucas Wilian Gonçalves de
author_facet Souza, Lucas Wilian Gonçalves de
author_role author
dc.contributor.advisor-co1.fl_str_mv Perini, Ana Paula
dc.contributor.advisor-co1Lattes.fl_str_mv http://lattes.cnpq.br/4681700210308237
dc.contributor.advisor1.fl_str_mv Neves, Lucio Pereira
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/9028304261745922
dc.contributor.referee1.fl_str_mv Milagre, Selma Terezinha
dc.contributor.referee1Lattes.fl_str_mv http://lattes.cnpq.br/4980687835840176
dc.contributor.referee2.fl_str_mv Caldas, Linda Viola Ehlin
dc.contributor.referee2Lattes.fl_str_mv http://lattes.cnpq.br/2032000100824080
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/2802586397251897
dc.contributor.author.fl_str_mv Souza, Lucas Wilian Gonçalves de
contributor_str_mv Perini, Ana Paula
Neves, Lucio Pereira
Milagre, Selma Terezinha
Caldas, Linda Viola Ehlin
dc.subject.cnpq.fl_str_mv CNPQ::ENGENHARIAS::ENGENHARIA BIOMEDICA
topic CNPQ::ENGENHARIAS::ENGENHARIA BIOMEDICA
ERCP
Ionizing Radiation
Monte Carlo Simulation
Dosimetry
Radiation Protection
Radiação Ionizante
Simulação de Monte Carlo
Dosimetria
Proteção Radiológica
dc.subject.por.fl_str_mv ERCP
Ionizing Radiation
Monte Carlo Simulation
Dosimetry
Radiation Protection
Radiação Ionizante
Simulação de Monte Carlo
Dosimetria
Proteção Radiológica
description The contemporary life style and the aging of world population have set a favorable scenario to the increase of hepatobiliary and pancreatic diseases. The Endoscopic Retrograde Cholangiopancreatography (ERCP) is one of the main medical techniques employed to diagnose and treat those diseases. ERCP is a fluoroscopy guided procedure, therefore it exposes patient and medical staff to ionizing radiation. This exposure may lead to tissue reactions and cancer later in life. The objective of this work was to apply Monte Carlo (MC) simulation to evaluate patient and staff radiation exposure during ERCP procedures. The simulated scenario reproduced a typical ERCP room equipped with an over-couch x-ray system. MASH3 and FASH3 virtual anthropomorphic phantoms were utilised to represent the patient, the physician and the assistant physician. The patient was placed in prone position on the table. The staff wore 0.5 mm Pb apron, thyroid collar and eyewear. The fluoroscopic parameters were tube voltage of 70, 80, 90, 100 and 110 kVp; the Field of View (FOV) sizes were 15×15 cm2, 17×17 cm2, 22×22 cm2, 25×25 cm2, 31×31 cm2 and 38×38 cm2. The x-ray spectra were simulated in SRS78 software and the Monte Carlo simulations were implemented in the Monte Carlo N-Particle eXtended (MCNPX) (version 2.7.0) code. For a given tube voltage, the results show an increase of patient conversion coefficients for effective dose CC[E] values for FOV sizes increments until the irradiated area suppressed patient area, then for larger FOV sizes, the CC[E] values decreased. For a defined FOV size, the patient CC[E] values raised as the tube voltage was increased. Concerning the staff, the CC[E] values increased for elevated tube voltages, given a fixed FOV size. Their CC[E] values also raised when the tube voltage was unchanged but the FOV sizes were expanded. The effective dose calculated from the mean CC[E] values and Dose Area Product (DAP) from the literature are in agreement with previous works. The estimated conversion coefficients for equivalent dose CC[HT] values are also consistent with the literature. This work presents the first results of a greater project focused on the radiation protection at an university hospital.
publishDate 2020
dc.date.accessioned.fl_str_mv 2020-04-07T11:32:35Z
dc.date.available.fl_str_mv 2020-04-07T11:32:35Z
dc.date.issued.fl_str_mv 2020-03-05
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
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dc.identifier.citation.fl_str_mv SOUZA, Lucas Wilian Gonçalves de. Evaluation of occupational exposures in Endoscopic Retrograde Cholangiopancreatography using Monte Carlo simulation. 2020. 93 f.(Mestrado em Engenharia Biomédica) - Universidade Federal de Uberlândia, Uberlândia, 2020. Disponível em: http://doi.org/10.14393/ufu.di.2020.295.
dc.identifier.uri.fl_str_mv https://repositorio.ufu.br/handle/123456789/29138
dc.identifier.doi.pt_BR.fl_str_mv http://doi.org/10.14393/ufu.di.2020.295
identifier_str_mv SOUZA, Lucas Wilian Gonçalves de. Evaluation of occupational exposures in Endoscopic Retrograde Cholangiopancreatography using Monte Carlo simulation. 2020. 93 f.(Mestrado em Engenharia Biomédica) - Universidade Federal de Uberlândia, Uberlândia, 2020. Disponível em: http://doi.org/10.14393/ufu.di.2020.295.
url https://repositorio.ufu.br/handle/123456789/29138
http://doi.org/10.14393/ufu.di.2020.295
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dc.publisher.none.fl_str_mv Universidade Federal de Uberlândia
dc.publisher.program.fl_str_mv Programa de Pós-graduação em Engenharia Biomédica
dc.publisher.country.fl_str_mv Brasil
publisher.none.fl_str_mv Universidade Federal de Uberlândia
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