Preval?ncia e diagn?stico de pacientes com Leucemia Linfoc?tica Cr?nica no Extremo Sul da Bahia, Brasil

Detalhes bibliográficos
Ano de defesa: 2023
Autor(a) principal: Ribeiro, Alessandro Martins
Orientador(a): Petinari, Roberta Barbizan
Banca de defesa: Não Informado pela instituição
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: UFVJM
Programa de Pós-Graduação: Não Informado pela instituição
Departamento: Não Informado pela instituição
País: Não Informado pela instituição
Link de acesso: http://acervo.ufvjm.edu.br/jspui/handle/1/3214
Resumo: Linha de pesquisa: Fisiopatologia e Diagn?sticos de Doen?as.
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spelling Ribeiro, Alessandro MartinsPetinari, Roberta BarbizanAlves, Caio C?sar de SouzaEndlich, Patrick WanderLago, Vivian MirandaAlves, Caio C?sar de SouzaUniversidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM)Petinari, Roberta Barbizan2023-06-23T18:07:18Z2023-06-23T18:07:18Z20232023-02-24RIBEIRO, Alessandro Martins. Preval?ncia e diagn?stico de pacientes com Leucemia Linfoc?tica Cr?nica no Extremo Sul da Bahia, Brasil. 2023. 89 p. Disserta??o (Mestrado em Ci?ncias da Sa?de) ? Programa de P?s-Gradua??o em Ci?ncias da Sa?de, Universidade Federal dos Vales do Jequitinhonha e Mucuri, Diamantina, 2023.http://acervo.ufvjm.edu.br/jspui/handle/1/3214Linha de pesquisa: Fisiopatologia e Diagn?sticos de Doen?as.A Leucemia Linfoc?tica Cr?nica (LLC) constitui-se como uma neoplasia proliferativa das c?lulas B, promovendo aumento do ba?o, f?gado e linfonodos, acometendo principalmente indiv?duos do sexo masculino, ra?a branca e com alta incid?ncia a partir dos 65 anos de idade, o diagn?stico consiste na realiza??o de exames como hemograma, mielograma, detec??o de marcadores celulares agrupadores de diferencia??o (CDs). Assim, objetivou-se identificar a preval?ncia de pacientes com LLC no Extremo Sul da Bahia, analisando os marcadores dos protocolos de diagn?stico laboratoriais. O presente estudo ? um coorte retrospectivo de 2015 a 2019, sob Aprova??o CAAE: 5.336.684 do CEP/CONEP, de prontu?rios de pacientes com LLC realizado na Unidade de Alta Complexidade em Oncologia ? UNACON, situado no munic?pio de Teixeira de Freitas, Bahia. Dessa forma, os resultados permitiram constatar que, conforme informa??es do DATASUS, dos 82 casos diagnosticados de doen?as linfoproliferativas cr?nicas, entre 2015 a 2019 do Extremo Sul da Bahia, seis (7,3%) eram de LLC. Na busca ativa dos prontu?rios com caracter?stica cl?nico-epidemiol?gica, 66,7% eram em pacientes homens; com 50% de indiv?duos brancos e pardos, apresentando linfocitose, plaquetopenia e anemia normoc?tica-normocr?mica (50%), um caso (16,7%) portando Manchas de Gumprecht e um caso (16,7%) apresentando CD79 e IGV15. Quanto ?s principais conclus?es do estudo realizado, viu-se que os marcadores de diagn?stico mais utilizados compreenderam a realiza??o de exames hematol?gicos como hemograma e mielograma, incluindo caracter?sticas hematol?gicas/bioqu?micas, em especial a linfocitose, leucocitose, plaquetopenia, anemia, com destaque para as caracter?sticas imunofenot?picas, na verifica??o de CDs 19 e 79, sendo a preval?ncia no Extremo Sul da Bahia de 7,3% de casos diagnosticados com LLC.Submitted by Jos? Henrique Henrique (jose.neves@ufvjm.edu.br) on 2023-06-22T22:34:39Z No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) alessandro_martins_ribeiro.pdf: 2552715 bytes, checksum: 08e7dd26f7737bc7927caf10da53559a (MD5)Approved for entry into archive by Jos? Henrique Henrique (jose.neves@ufvjm.edu.br) on 2023-06-23T18:07:18Z (GMT) No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) alessandro_martins_ribeiro.pdf: 2552715 bytes, checksum: 08e7dd26f7737bc7927caf10da53559a (MD5)Made available in DSpace on 2023-06-23T18:07:18Z (GMT). No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) alessandro_martins_ribeiro.pdf: 2552715 bytes, checksum: 08e7dd26f7737bc7927caf10da53559a (MD5) Previous issue date: 2023Disserta??o (Mestrado) ? Programa de P?s-gradua??o em Ci?ncias da Sa?de, Universidade Federal dos Vales do Jequitinhonha e Mucuri, 2023.Chronic Lymphocytic Leukemia (CLL) is a proliferative B-cell neoplasm, promoting enlargement of the spleen, liver and lymph nodes, affecting mainly white males, with a high incidence after 65 years of age. Thus, we aimed to identify the prevalence of patients with CLL in the Extreme South of Bahia, analyzing the markers of laboratory diagnostic protocols. The present study is a retrospective cohort from 2015 to 2019, under CAAE Approval: 5.336.684 from CEP/CONEP, of medical records of patients with LLC performed at the High Complexity Oncology Unit - UNACON, located in the municipality of Teixeira de Freitas, Bahia. Thus, the results allowed to verify that, according to information from DATASUS, of the 82 diagnosed cases of chronic lymphoproliferative diseases, between 2015 and 2019 in the Extreme South of Bahia, six (7.3%) were of LLC. In the active search of medical records with clinical-epidemiological characteristic, 66.7% were in male patients; with 50% white and brown individuals, presenting lymphocytosis, thrombocytopenia and normocytic-normochromic anemia (50%), one case (16.7%) carrying Gumprecht spots and one case (16.7%) presenting CD79 and IGV15. As for the main conclusions of the study, it was seen that the most used diagnostic markers comprised the performance of hematological tests such as hemogram and myelogram, including hematological/biochemical characteristics, especially lymphocytosis, leukocytosis, thrombocytopenia, anemia, with emphasis on immunophenotypic characteristics, in the verification of CDs 19 and 79, with the prevalence in the Far South of Bahia being 7.3% of cases diagnosed with LLC.porUFVJMA concess?o da licen?a deste item refere-se ao ? termo de autoriza??o impresso assinado pelo autor, assim como na licen?a Creative Commons, com as seguintes condi??es: Na qualidade de titular dos direitos de autor da publica??o, autorizo a Universidade Federal dos Vales do Jequitinhonha e Mucuri e o IBICT a disponibilizar por meio de seus reposit?rios, sem ressarcimento dos direitos autorais, de acordo com a Lei n? 9610/98, o texto integral da obra disponibilizada, conforme permiss?es assinaladas, para fins de leitura, impress?o e/ou download, a t?tulo de divulga??o da produ??o cient?fica brasileira, e preserva??o, a partir desta data.info:eu-repo/semantics/openAccessPreval?ncia e diagn?stico de pacientes com Leucemia Linfoc?tica Cr?nica no Extremo Sul da Bahia, Brasilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisLeucemia Linfoc?tica Cr?nicaPreval?nciaAltera??es hematol?gicasAltera??es imunofenot?picasChronic Lymphocytic LeukemiaPrevalenceHematological changesImmunophenotypic alterationsreponame:Repositório Institucional da UFVJMinstname:Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM)instacron:UFVJMTEXTalessandro_martins_ribeiro.pdf.txtalessandro_martins_ribeiro.pdf.txtExtracted texttext/plain138538http://acervo.ufvjm.edu.br/jspui/bitstream/1/3214/6/alessandro_martins_ribeiro.pdf.txt2fcd7b995bbc423442f661391f62e7baMD56LICENSElicense.txtlicense.txttext/plain; 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dc.title.pt_BR.fl_str_mv Preval?ncia e diagn?stico de pacientes com Leucemia Linfoc?tica Cr?nica no Extremo Sul da Bahia, Brasil
title Preval?ncia e diagn?stico de pacientes com Leucemia Linfoc?tica Cr?nica no Extremo Sul da Bahia, Brasil
spellingShingle Preval?ncia e diagn?stico de pacientes com Leucemia Linfoc?tica Cr?nica no Extremo Sul da Bahia, Brasil
Ribeiro, Alessandro Martins
Leucemia Linfoc?tica Cr?nica
Preval?ncia
Altera??es hematol?gicas
Altera??es imunofenot?picas
Chronic Lymphocytic Leukemia
Prevalence
Hematological changes
Immunophenotypic alterations
title_short Preval?ncia e diagn?stico de pacientes com Leucemia Linfoc?tica Cr?nica no Extremo Sul da Bahia, Brasil
title_full Preval?ncia e diagn?stico de pacientes com Leucemia Linfoc?tica Cr?nica no Extremo Sul da Bahia, Brasil
title_fullStr Preval?ncia e diagn?stico de pacientes com Leucemia Linfoc?tica Cr?nica no Extremo Sul da Bahia, Brasil
title_full_unstemmed Preval?ncia e diagn?stico de pacientes com Leucemia Linfoc?tica Cr?nica no Extremo Sul da Bahia, Brasil
title_sort Preval?ncia e diagn?stico de pacientes com Leucemia Linfoc?tica Cr?nica no Extremo Sul da Bahia, Brasil
author Ribeiro, Alessandro Martins
author_facet Ribeiro, Alessandro Martins
author_role author
dc.contributor.referee.none.fl_str_mv Petinari, Roberta Barbizan
Alves, Caio C?sar de Souza
Endlich, Patrick Wander
Lago, Vivian Miranda
dc.contributor.advisorco.none.fl_str_mv Alves, Caio C?sar de Souza
dc.contributor.institution.pt_BR.fl_str_mv Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM)
dc.contributor.author.fl_str_mv Ribeiro, Alessandro Martins
dc.contributor.advisor1.fl_str_mv Petinari, Roberta Barbizan
contributor_str_mv Petinari, Roberta Barbizan
dc.subject.keyword.pt_BR.fl_str_mv Leucemia Linfoc?tica Cr?nica
Preval?ncia
Altera??es hematol?gicas
Altera??es imunofenot?picas
topic Leucemia Linfoc?tica Cr?nica
Preval?ncia
Altera??es hematol?gicas
Altera??es imunofenot?picas
Chronic Lymphocytic Leukemia
Prevalence
Hematological changes
Immunophenotypic alterations
dc.subject.keyword.en.fl_str_mv Chronic Lymphocytic Leukemia
Prevalence
Hematological changes
Immunophenotypic alterations
description Linha de pesquisa: Fisiopatologia e Diagn?sticos de Doen?as.
publishDate 2023
dc.date.submitted.none.fl_str_mv 2023-02-24
dc.date.accessioned.fl_str_mv 2023-06-23T18:07:18Z
dc.date.available.fl_str_mv 2023-06-23T18:07:18Z
dc.date.issued.fl_str_mv 2023
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.citation.fl_str_mv RIBEIRO, Alessandro Martins. Preval?ncia e diagn?stico de pacientes com Leucemia Linfoc?tica Cr?nica no Extremo Sul da Bahia, Brasil. 2023. 89 p. Disserta??o (Mestrado em Ci?ncias da Sa?de) ? Programa de P?s-Gradua??o em Ci?ncias da Sa?de, Universidade Federal dos Vales do Jequitinhonha e Mucuri, Diamantina, 2023.
dc.identifier.uri.fl_str_mv http://acervo.ufvjm.edu.br/jspui/handle/1/3214
identifier_str_mv RIBEIRO, Alessandro Martins. Preval?ncia e diagn?stico de pacientes com Leucemia Linfoc?tica Cr?nica no Extremo Sul da Bahia, Brasil. 2023. 89 p. Disserta??o (Mestrado em Ci?ncias da Sa?de) ? Programa de P?s-Gradua??o em Ci?ncias da Sa?de, Universidade Federal dos Vales do Jequitinhonha e Mucuri, Diamantina, 2023.
url http://acervo.ufvjm.edu.br/jspui/handle/1/3214
dc.language.iso.fl_str_mv por
language por
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv UFVJM
publisher.none.fl_str_mv UFVJM
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFVJM
instname:Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM)
instacron:UFVJM
instname_str Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM)
instacron_str UFVJM
institution UFVJM
reponame_str Repositório Institucional da UFVJM
collection Repositório Institucional da UFVJM
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