Associação cetamina-xilazina, tiletamina-zolazepam, e tiletamina-zolazepam-levomepromazina na anestesia de capivara (Hydrochoerus hydrochaeris)

• Ano de defesa: 2003
• Autor(a) principal: Nishiyama, Shirley Miti
• Orientador(a): Pompermayer, Luiz Gonzaga
• Banca de defesa: Paula, Tarcízio Antônio Rego de , Carlo, Ricardo Junqueira Del , Borges, Andrea Pacheco Batista , Costa, Deiler Sampaio
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de Viçosa
• Programa de Pós-Graduação: Mestrado em Medicina Veterinária
• Departamento: Biotecnologia, diagnóstico e controle de doenças; Epidemiologia e controle de qualidade de prod. de
• País: BR
• Palavras-chave em Português: Capivara; Tiletamina-zolazepam-levomepromazina; Anestesia; Hydrochoerus hydrochaeris
• Palavras-chave em Inglês: Capybara; Tiletamine-zolazepam-levomepromazine; Anesthesia; Hydrochoerus hydrochaeris
• Área do conhecimento CNPq: CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA::CLINICA E CIRURGIA ANIMAL
• Link de acesso: http://locus.ufv.br/handle/123456789/5196

Despite the great number of capybara (Hydrochoerus hydrochaeris) breedings, this species reproduction, handling, nutrition, diseases and its related agents are still studied. Its study requires chemical immobilization specially when the physical restraint can be a stressing factor for the animal and also risky for the technical team. In practice, the chemical restraint of capybaras is accomplished in an empiric way, using drugs and dosages based on previous handlings, which can result in unexpected, undesirable reactions and even in the animal s death. Thus, the present work had as objectives to evaluate comparatively the effects of the ketamine-xylazine, tiletamine-zolazepam and tiletamine-zolazepam-levomepromazine combinations as anesthetic agents for capybaras. For that, 30 adult capybaras, males and females, with medium weight of 43 kg, were randomly distributed in three experimental groups of the same number, receiving the following combinations: ketamine 10,0 mg/kg and xylazine 0,5 mg/kg (G1); tiletamine-zolazepam 5,0 mg/kg (G2); tiletamine-zolazepam 5,0 mg/kg and levomepromazine 0,5 mg/kg (G3). The drugs were administered intramuscularly through darts and blowgun, and the doses were calculated in agreement with the estimative weight of the animals. The real dose administered was obtained after immobilization, when the animals allowed the weighing. Respiratory rate; oxyhemoglobin saturation; heart rate; systolic, mean and diastolic blood pressure; capillary refill time; rectal body temperature, analgesia and muscular relaxation degree; and reflexes, were evaluated from the moment that the animal allowed the manipulation and after every 15 minutes, until completing 60 minutes. It was concluded that the ketamine-xylazine combination (10,0 and 0,5 mg/kg, respectively) promoted the best tegument analgesia. When the kind of intervention doesn't demand intense analgesia, the dose used with the tiletamine-zolazepam combination (5,0 mg/kg) is enough for about one hour immobilization. The addition of the levomepromazine (0,5 mg/kg) improves analgesia and muscular relaxation, increases both duration of anesthesia and recovery time making the last calmer. For more painful interventions in capybaras, it will be necessary more studies to adjust the dose of the tiletamina-zolazepam, combined or not with the levomepromazine. The use of the levomepromazine hydrochloride at 0,5% for the dilution of the lyophilized form of tiletamine-zolazepam didn't present any inconvenience and was advantageous for use in darts, due to not increase the administered volume.