Diferentes doses de laser no tratamento neural após compressão experimental do nervo ciático de ratos submetidos a hipocinesia dos membros pélvicos

• Ano de defesa: 2010
• Autor(a) principal: Brito, Ana Flora Sousa de
• Orientador(a): Carlo, Ricardo Junqueira Del
• Banca de defesa: Borges, Andrea Pacheco Batista , Monteiro, Betânia Souza
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de Viçosa
• Programa de Pós-Graduação: Mestrado em Medicina Veterinária
• Departamento: Biotecnologia, diagnóstico e controle de doenças; Epidemiologia e controle de qualidade de prod. de
• País: BR
• Palavras-chave em Português: Hipocinesia; Laser terapêutico; Lesão nervosa
• Palavras-chave em Inglês: Hypokinesia; Laser therapy; Nerve injury
• Área do conhecimento CNPq: CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA::CLINICA E CIRURGIA ANIMAL::CLINICA CIRURGICA ANIMAL
• Link de acesso: http://locus.ufv.br/handle/123456789/5049

Laser irradiation is frequently used as treatment for many pathologies of skeletal muscle, including peripheral nerves lesion. Therefore, the aim of this research was to evaluate by clinical and morfometric analysis the effects of laser therapy on neural and muscle repair after crushing of sciatic nerve and hind limb unloading. 48 Wistar male rats machos, with 60 days old, were divided in three groups with 16 animals each, and they were performed as one control group (GA) and two irradiated groups (GB with 4 J/cm² dose; GC with 6 J/cm² dose). After the sciatic nerve was crushed animals were maintained under hind limb suspension and received laser (GaAlAs) irradiation three times per week, during 14 or 28 days. The sciatic functional index (SFI) were measured before surgery, at 14 and 28 days, recovery was observed in all groups especially to GA at 28 days. Morfometric analysis of the nerve showed that the nerve recovery was better to the treated groups, specially at 14 days. The muscle morfometric analysis weren’t effected by laser therapy. Taken together the results allowed to conclude that laser therapy promotes morphological recover of the nerve, specially until 14 days. Yet laser isn’t able to influence the muscle recovery and function.