Alimentos Funcionais Atenuam os Efeitos Tóxicos à Exposição Crônica da Fumaça do Cigarro nos Testiculos e Epididimo de Ratos

• Ano de defesa: 2017
• Autor(a) principal: FALVO, Adriano
• Orientador(a): BREMER NETO, Hermann
• Banca de defesa: MOURAD, Amouni Mohmoud , GIOMETTI, Inês Cristina
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade do Oeste Paulista
• Programa de Pós-Graduação: Mestrado em Ciência Animal
• Departamento: Mestrado em Ciência Animal
• País: Brasil
• Palavras-chave em Português: Alimentos funcionais. Prebióticos. Probióticos. Simbióticos
• Palavras-chave em Inglês: Functional food. Prebiotics. Probiotics. Symbiotics
• Área do conhecimento CNPq: CIENCIAS AGRARIAS::MEDICINA VETERINARIA
• Link de acesso: http://bdtd.unoeste.br:8080/jspui/handle/jspui/1055

According to the World Health Organization (WHO), cigarette smoking accounts for 5 million annual deaths. Cigarette smoke causes malevolent effects in many other systems, including the male reproductive system and functional foods that may mitigate the toxic effects of cigarette smoking. The objective of the present study was to investigate the possible attenuating effects of prebiotic, probiotic and symbiotic oral supplementation on the testis and epididymis of growing rats exposed to cigarette smoke. To perform the present study, 72 male rats were randomly divided into eight groups: control; probiotic; Prebiotic (MOS); Symbiotic; Smoking Control; Prebiotic Tobacco; Probiotic Smoking; And Smoking Symbiotic. The animals in the smoking groups were exposed to cigarette smoke for one hour daily, divided into two 30-minute periods, five days a week. After the experimental period, the animals were anesthetized, sacrificed, the testes and epididymides were removed. Microscopic lesions were analyzed using the chi-square test, Fisher's exact test or G test at 5% significance. The results showed that the smoking groups had a higher prevalence of lesions in the testes and epididymis when compared to the control groups. Functional, prebiotic, probiotic, and symbiotic foods attenuated the harmful effects of chronic exposure to cigarette smoke in the testis and epididymis. The results allow us to state that functional, probiotic, prebiotic and symbiotic foods can attenuate the chronic harmful effects of passive smoking on the testis and epididymis of rats during the growth phase.