Alterações vasculares em beijupirás cultivados em sistema offshore
Ano de defesa: | 2014 |
---|---|
Autor(a) principal: | |
Orientador(a): | |
Banca de defesa: | , , |
Tipo de documento: | Tese |
Tipo de acesso: | Acesso aberto |
Idioma: | por |
Instituição de defesa: |
Universidade Federal Rural de Pernambuco
|
Programa de Pós-Graduação: |
Programa de Pós-Graduação em Ciência Veterinária
|
Departamento: |
Departamento de Medicina Veterinária
|
País: |
Brasil
|
Palavras-chave em Português: | |
Área do conhecimento CNPq: | |
Link de acesso: | http://www.tede2.ufrpe.br:8080/tede2/handle/tede2/8622 |
Resumo: | Currently there is a growing interest in the development of projects aiming at the implementation of farmed beijupirá (Rachycentron canadum), requiring broaden knowledge about nutritional requirements, reproductive cycle and habit of the species, especially considering that these factors can trigger the onset of diseases, including circulatory diseases. Among them, atherosclerosis which is a chronic inflammatory disease that leads to changes in the arterial wall. In the present study, were investigated vascular diseases in fish, in the point of view of pathological anatomy. Thus, were evaluated morphologically vascular changes in tissues collected from beijupirá farmed in offshore in Pernambuco. Cardiac tissue samples were collected and submitted to histopathology and transmission electron microscopy (TEM) for the presence of alterations, with subsequent identification of vascular lesions suggestive of atherosclerosis. The histological slides were stained with hematoxylin-eosin (HE), blue alcian, periodic acid of Schiffh (PAS) and reticulin of Gomori. In the morphometric analysis 158 arteries were evaluated, and the images were analyzed with the aid of software. The data concerning to the proportion of the lumen area compared to the area of the media tunic were analyzed according to the Beta regression models for rates and proportions. Arterial lesions were observed throughout the farmed period, especially in the vascular wall, with hyperplasia of intima and media tunic, formation of atheromatous plaque, infiltration of foam cells and signs of luminal stenosis. By means of TEM, were observed changes in the structure of coronary, with thickening of endothelium and basement membrane, proliferation of fibroblasts and collagen fibers, with accumulation of lipid material subendothelial, cell debris adhered in the basement membrane and presence of pinocytotics vesicles with isolated lysosomes. It was found that fish of the specie Rachycentron canadum farmed in captivity develop arterial lesion of chronic inflammatory degenerative type, and also it was found that the increase in weight gain contributes to the reduction of the lumen area, leading to arterial obstruction. |
id |
URPE_ff8d7306b67bf7151f06a207eff7e72b |
---|---|
oai_identifier_str |
oai:tede2:tede2/8622 |
network_acronym_str |
URPE |
network_name_str |
Biblioteca Digital de Teses e Dissertações da UFRPE |
repository_id_str |
|
spelling |
MENDES, Emiko ShinozakiSANTOS, Fernando Leandro dosROMANO, Luis AlbertoOLIVEIRA, Andrea Alice da FonsecaPEREIRA, Márcia de FigueiredoMEIRELES, Fernanda Silva dehttp://lattes.cnpq.br/2583049624842407PEDROSA, Virgínia Fonseca2022-08-23T11:44:39Z2014-02-25PEDROSA, Virgínia Fonseca. Alterações vasculares em beijupirás cultivados em sistema offshore. 2014. 85 f. Tese (Programa de Pós-Graduação em Ciência Veterinária) - Universidade Federal Rural de Pernambuco, Recife.http://www.tede2.ufrpe.br:8080/tede2/handle/tede2/8622Currently there is a growing interest in the development of projects aiming at the implementation of farmed beijupirá (Rachycentron canadum), requiring broaden knowledge about nutritional requirements, reproductive cycle and habit of the species, especially considering that these factors can trigger the onset of diseases, including circulatory diseases. Among them, atherosclerosis which is a chronic inflammatory disease that leads to changes in the arterial wall. In the present study, were investigated vascular diseases in fish, in the point of view of pathological anatomy. Thus, were evaluated morphologically vascular changes in tissues collected from beijupirá farmed in offshore in Pernambuco. Cardiac tissue samples were collected and submitted to histopathology and transmission electron microscopy (TEM) for the presence of alterations, with subsequent identification of vascular lesions suggestive of atherosclerosis. The histological slides were stained with hematoxylin-eosin (HE), blue alcian, periodic acid of Schiffh (PAS) and reticulin of Gomori. In the morphometric analysis 158 arteries were evaluated, and the images were analyzed with the aid of software. The data concerning to the proportion of the lumen area compared to the area of the media tunic were analyzed according to the Beta regression models for rates and proportions. Arterial lesions were observed throughout the farmed period, especially in the vascular wall, with hyperplasia of intima and media tunic, formation of atheromatous plaque, infiltration of foam cells and signs of luminal stenosis. By means of TEM, were observed changes in the structure of coronary, with thickening of endothelium and basement membrane, proliferation of fibroblasts and collagen fibers, with accumulation of lipid material subendothelial, cell debris adhered in the basement membrane and presence of pinocytotics vesicles with isolated lysosomes. It was found that fish of the specie Rachycentron canadum farmed in captivity develop arterial lesion of chronic inflammatory degenerative type, and also it was found that the increase in weight gain contributes to the reduction of the lumen area, leading to arterial obstruction.Atualmente existe um crescente interesse no desenvolvimento de projetos visando à implantação do cultivo de beijupirá (Rachycentron canadum), necessitando ampliar os conhecimentos acerca das necessidades nutricionais, ciclo reprodutivo e hábito da espécie, principalmente se considerar que estes fatores podem desencadear o aparecimento de doenças, inclusive por patologias circulatórias. Dentre estas, destaca-se a aterosclerose, uma doença inflamatória crônica que conduz a alterações na parede arterial. No presente trabalho, foram pesquisadas doenças vasculares no peixe, sob o ponto de vista da anatomia patológica. Sendo assim, foram avaliadas morfologicamente alterações vasculares em tecidos coletados de beijupirá provenientes de cultivo offshore em Pernambuco. Amostras de tecido cardíaco foram coletadas e submetidas à histopatologia e microscopia eletrônica de transmissão (MET), para averiguar a presença de alterações, com posterior identificação de lesões vasculares sugestivas de aterosclerose. As lâminas histológicas foram coradas por hematoxilina-eosina (HE), alcian blue, ácido periódico de Schiffh (PAS) e reticulina de Gomori. Na análise morfométrica 158 vasos arteriais foram avaliados, sendo as imagens analisadas com auxílio de um software. Os dados referentes à proporção da área do lúmen em relação à área da túnica média foram analisados de acordo com os modelos de regressão Beta para taxas e proporções. Foram observadas lesões arteriais em todo período de cultivo, principalmente na parede vascular, com hiperplasia de túnica íntima e média, formação de placa ateromatosa, infiltração de células espumosas e sinais de estenose luminal. Por meio da MET foram observadas alterações na estrutura das coronárias, com espessamento do endotélio e membrana basal, proliferação de fibroblastos e fibras colágenas, com acúmulo de material lipídico subendotelial, resíduos celulares aderidos à membrana basal e vesículas pinocitóticas com presença de lisossomos isolados. Foi constatado que os peixes da espécie Rachycentron canadum criados em cativeiro desenvolvem lesão arterial do tipo crônica degenerativa inflamatória e que o aumento no ganho de peso contribui para a redução da área do lúmen, levando a obstrução arterial, possivelmente com envolvimento de fatores nutricionais no surgimento das lesões.Submitted by Mario BC (mario@bc.ufrpe.br) on 2022-08-23T11:44:39Z No. of bitstreams: 1 Virginia Fonseca Pedrosa.pdf: 2032137 bytes, checksum: e428083fd8ac94ea897ea2227b02cc67 (MD5)Made available in DSpace on 2022-08-23T11:44:39Z (GMT). No. of bitstreams: 1 Virginia Fonseca Pedrosa.pdf: 2032137 bytes, checksum: e428083fd8ac94ea897ea2227b02cc67 (MD5) Previous issue date: 2014-02-25application/pdfporUniversidade Federal Rural de PernambucoPrograma de Pós-Graduação em Ciência VeterináriaUFRPEBrasilDepartamento de Medicina VeterináriaBeijupiráRachycentron canadumAteroscleroseHiperplasiaDoença vascularCIENCIAS AGRARIAS::MEDICINA VETERINARIAAlterações vasculares em beijupirás cultivados em sistema offshoreinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/doctoralThesis-3061482854177903105600600600-3020210563763616780453670264235017319info:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da UFRPEinstname:Universidade Federal Rural de Pernambuco (UFRPE)instacron:UFRPEORIGINALVirginia Fonseca Pedrosa.pdfVirginia Fonseca Pedrosa.pdfapplication/pdf2032137http://www.tede2.ufrpe.br:8080/tede2/bitstream/tede2/8622/2/Virginia+Fonseca+Pedrosa.pdfe428083fd8ac94ea897ea2227b02cc67MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-82165http://www.tede2.ufrpe.br:8080/tede2/bitstream/tede2/8622/1/license.txtbd3efa91386c1718a7f26a329fdcb468MD51tede2/86222022-08-23 08:44:39.276oai:tede2: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Biblioteca Digital de Teses e Dissertaçõeshttp://www.tede2.ufrpe.br:8080/tede/PUBhttp://www.tede2.ufrpe.br:8080/oai/requestbdtd@ufrpe.br ||bdtd@ufrpe.bropendoar:2022-08-23T11:44:39Biblioteca Digital de Teses e Dissertações da UFRPE - Universidade Federal Rural de Pernambuco (UFRPE)false |
dc.title.por.fl_str_mv |
Alterações vasculares em beijupirás cultivados em sistema offshore |
title |
Alterações vasculares em beijupirás cultivados em sistema offshore |
spellingShingle |
Alterações vasculares em beijupirás cultivados em sistema offshore PEDROSA, Virgínia Fonseca Beijupirá Rachycentron canadum Aterosclerose Hiperplasia Doença vascular CIENCIAS AGRARIAS::MEDICINA VETERINARIA |
title_short |
Alterações vasculares em beijupirás cultivados em sistema offshore |
title_full |
Alterações vasculares em beijupirás cultivados em sistema offshore |
title_fullStr |
Alterações vasculares em beijupirás cultivados em sistema offshore |
title_full_unstemmed |
Alterações vasculares em beijupirás cultivados em sistema offshore |
title_sort |
Alterações vasculares em beijupirás cultivados em sistema offshore |
author |
PEDROSA, Virgínia Fonseca |
author_facet |
PEDROSA, Virgínia Fonseca |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
MENDES, Emiko Shinozaki |
dc.contributor.advisor-co1.fl_str_mv |
SANTOS, Fernando Leandro dos |
dc.contributor.advisor-co2.fl_str_mv |
ROMANO, Luis Alberto |
dc.contributor.referee1.fl_str_mv |
OLIVEIRA, Andrea Alice da Fonseca |
dc.contributor.referee2.fl_str_mv |
PEREIRA, Márcia de Figueiredo |
dc.contributor.referee3.fl_str_mv |
MEIRELES, Fernanda Silva de |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/2583049624842407 |
dc.contributor.author.fl_str_mv |
PEDROSA, Virgínia Fonseca |
contributor_str_mv |
MENDES, Emiko Shinozaki SANTOS, Fernando Leandro dos ROMANO, Luis Alberto OLIVEIRA, Andrea Alice da Fonseca PEREIRA, Márcia de Figueiredo MEIRELES, Fernanda Silva de |
dc.subject.por.fl_str_mv |
Beijupirá Rachycentron canadum Aterosclerose Hiperplasia Doença vascular |
topic |
Beijupirá Rachycentron canadum Aterosclerose Hiperplasia Doença vascular CIENCIAS AGRARIAS::MEDICINA VETERINARIA |
dc.subject.cnpq.fl_str_mv |
CIENCIAS AGRARIAS::MEDICINA VETERINARIA |
description |
Currently there is a growing interest in the development of projects aiming at the implementation of farmed beijupirá (Rachycentron canadum), requiring broaden knowledge about nutritional requirements, reproductive cycle and habit of the species, especially considering that these factors can trigger the onset of diseases, including circulatory diseases. Among them, atherosclerosis which is a chronic inflammatory disease that leads to changes in the arterial wall. In the present study, were investigated vascular diseases in fish, in the point of view of pathological anatomy. Thus, were evaluated morphologically vascular changes in tissues collected from beijupirá farmed in offshore in Pernambuco. Cardiac tissue samples were collected and submitted to histopathology and transmission electron microscopy (TEM) for the presence of alterations, with subsequent identification of vascular lesions suggestive of atherosclerosis. The histological slides were stained with hematoxylin-eosin (HE), blue alcian, periodic acid of Schiffh (PAS) and reticulin of Gomori. In the morphometric analysis 158 arteries were evaluated, and the images were analyzed with the aid of software. The data concerning to the proportion of the lumen area compared to the area of the media tunic were analyzed according to the Beta regression models for rates and proportions. Arterial lesions were observed throughout the farmed period, especially in the vascular wall, with hyperplasia of intima and media tunic, formation of atheromatous plaque, infiltration of foam cells and signs of luminal stenosis. By means of TEM, were observed changes in the structure of coronary, with thickening of endothelium and basement membrane, proliferation of fibroblasts and collagen fibers, with accumulation of lipid material subendothelial, cell debris adhered in the basement membrane and presence of pinocytotics vesicles with isolated lysosomes. It was found that fish of the specie Rachycentron canadum farmed in captivity develop arterial lesion of chronic inflammatory degenerative type, and also it was found that the increase in weight gain contributes to the reduction of the lumen area, leading to arterial obstruction. |
publishDate |
2014 |
dc.date.issued.fl_str_mv |
2014-02-25 |
dc.date.accessioned.fl_str_mv |
2022-08-23T11:44:39Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/doctoralThesis |
format |
doctoralThesis |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
PEDROSA, Virgínia Fonseca. Alterações vasculares em beijupirás cultivados em sistema offshore. 2014. 85 f. Tese (Programa de Pós-Graduação em Ciência Veterinária) - Universidade Federal Rural de Pernambuco, Recife. |
dc.identifier.uri.fl_str_mv |
http://www.tede2.ufrpe.br:8080/tede2/handle/tede2/8622 |
identifier_str_mv |
PEDROSA, Virgínia Fonseca. Alterações vasculares em beijupirás cultivados em sistema offshore. 2014. 85 f. Tese (Programa de Pós-Graduação em Ciência Veterinária) - Universidade Federal Rural de Pernambuco, Recife. |
url |
http://www.tede2.ufrpe.br:8080/tede2/handle/tede2/8622 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.program.fl_str_mv |
-3061482854177903105 |
dc.relation.confidence.fl_str_mv |
600 600 600 |
dc.relation.department.fl_str_mv |
-3020210563763616780 |
dc.relation.cnpq.fl_str_mv |
453670264235017319 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Federal Rural de Pernambuco |
dc.publisher.program.fl_str_mv |
Programa de Pós-Graduação em Ciência Veterinária |
dc.publisher.initials.fl_str_mv |
UFRPE |
dc.publisher.country.fl_str_mv |
Brasil |
dc.publisher.department.fl_str_mv |
Departamento de Medicina Veterinária |
publisher.none.fl_str_mv |
Universidade Federal Rural de Pernambuco |
dc.source.none.fl_str_mv |
reponame:Biblioteca Digital de Teses e Dissertações da UFRPE instname:Universidade Federal Rural de Pernambuco (UFRPE) instacron:UFRPE |
instname_str |
Universidade Federal Rural de Pernambuco (UFRPE) |
instacron_str |
UFRPE |
institution |
UFRPE |
reponame_str |
Biblioteca Digital de Teses e Dissertações da UFRPE |
collection |
Biblioteca Digital de Teses e Dissertações da UFRPE |
bitstream.url.fl_str_mv |
http://www.tede2.ufrpe.br:8080/tede2/bitstream/tede2/8622/2/Virginia+Fonseca+Pedrosa.pdf http://www.tede2.ufrpe.br:8080/tede2/bitstream/tede2/8622/1/license.txt |
bitstream.checksum.fl_str_mv |
e428083fd8ac94ea897ea2227b02cc67 bd3efa91386c1718a7f26a329fdcb468 |
bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 |
repository.name.fl_str_mv |
Biblioteca Digital de Teses e Dissertações da UFRPE - Universidade Federal Rural de Pernambuco (UFRPE) |
repository.mail.fl_str_mv |
bdtd@ufrpe.br ||bdtd@ufrpe.br |
_version_ |
1794501137742692352 |