Investigação Epidemiológica de casos de brucelose humana no sul de Santa Catarina

Detalhes bibliográficos
Ano de defesa: 2018
Autor(a) principal: Lopes, Cyntia Michielin
Orientador(a): Não Informado pela instituição
Banca de defesa: Não Informado pela instituição
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Não Informado pela instituição
Programa de Pós-Graduação: Não Informado pela instituição
Departamento: Não Informado pela instituição
País: Não Informado pela instituição
Palavras-chave em Português:
Link de acesso: https://repositorio.animaeducacao.com.br/handle/ANIMA/3122
Resumo: Introduction: Brucellosis is a zoonotic disease, acquired through direct or indirect contact with infected animals. In humans, the symptoms are non-specific and often confused with other infectious diseases. Objective: To verify the seroprevalence and risk factors associated with bovine brucellosis transmission to humans. Methods: A cross-sectional study carried was out in municipalities in the Southern Region of Santa Catarina state. Blood was collected to serum obtentions for laboratorial diagnosis using the Indirect Immunoenzymatic Assay (ELISA) method and a questionnaire was used to collect sociodemographic data and risk factors. Results: Among the 139 participants included in the study, the seroprevalence was 14.4%. Prevalence of seropositive individuals living in the municipalities of Gravatal (25%). There was predominance of males (60%), mean age of 51.7 (± 15.6) years, level of primary schooling (60%), beginning of childhood activities (75%), occupational contact (80%) and time on property for more than five years (90%). The prevalence of unpasteurised milk (90%), boiled milk (89%), fresh cheese (91% and food with cheese (92%) was predominant). Predominance was manual milking (74%), contact with aborted placenta or fetus (88%) and non-use of Personal Protective Equipment (PPE) (80%). In the seropositive participants, symptoms were predominant: weight loss (19%), intermittent fever (17%), Seventy (70%) and profuse sweating (15%) were included in the study, with a median herd of 20 animals, predominantly of small breeders (57%), females (79%) and breeding animals susceptible to brucellosis (80 %), especially dogs (60%). Conclusion: It is concluded that the seroprevalence of brucellosis is high in relation to other studies carried out in Brazil and the non-specific symptoms make diagnostic suspicion difficult. An approach to the interaction between animal and human health can reduce the risk of dissemination and improve the diagnosis of brucellosis in humans.
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spelling Investigação Epidemiológica de casos de brucelose humana no sul de Santa CatarinaEpidemiological investigation of cases of human brucellosis in southern Santa CatarinaBrucella abortusZoonoseFatores de riscoSaúde PúblicaIntroduction: Brucellosis is a zoonotic disease, acquired through direct or indirect contact with infected animals. In humans, the symptoms are non-specific and often confused with other infectious diseases. Objective: To verify the seroprevalence and risk factors associated with bovine brucellosis transmission to humans. Methods: A cross-sectional study carried was out in municipalities in the Southern Region of Santa Catarina state. Blood was collected to serum obtentions for laboratorial diagnosis using the Indirect Immunoenzymatic Assay (ELISA) method and a questionnaire was used to collect sociodemographic data and risk factors. Results: Among the 139 participants included in the study, the seroprevalence was 14.4%. Prevalence of seropositive individuals living in the municipalities of Gravatal (25%). There was predominance of males (60%), mean age of 51.7 (± 15.6) years, level of primary schooling (60%), beginning of childhood activities (75%), occupational contact (80%) and time on property for more than five years (90%). The prevalence of unpasteurised milk (90%), boiled milk (89%), fresh cheese (91% and food with cheese (92%) was predominant). Predominance was manual milking (74%), contact with aborted placenta or fetus (88%) and non-use of Personal Protective Equipment (PPE) (80%). In the seropositive participants, symptoms were predominant: weight loss (19%), intermittent fever (17%), Seventy (70%) and profuse sweating (15%) were included in the study, with a median herd of 20 animals, predominantly of small breeders (57%), females (79%) and breeding animals susceptible to brucellosis (80 %), especially dogs (60%). Conclusion: It is concluded that the seroprevalence of brucellosis is high in relation to other studies carried out in Brazil and the non-specific symptoms make diagnostic suspicion difficult. An approach to the interaction between animal and human health can reduce the risk of dissemination and improve the diagnosis of brucellosis in humans.Introdução: A brucelose é uma doença zoonótica, adquirida pelo contato direto ou indireto com os animais infectados. Em seres humanos, os sintomas são inespecíficos e muitas vezes é confundida com outras doenças infecciosas. Objetivo: Verificar a soroprevalência e os fatores de risco associados a ocorrência da transmissão da brucelose de bovinos para os seres humanos. Métodos: Estudo transversal realizado em municípios da Região Sul de Santa Catarina. Foi coletado sangue para obtenção do soro para o diagnóstico laboratorial pelo método de Ensaio Imunoenzimático Indireto (ELISA) e aplicado questionário para coleta de dados sociodemográficos e fatores de risco. Resultados: Entre 139 participantes incluídos no estudo, a soroprevalência foi de 14,4%. Predominou soropositivos residentes nos municípios de Gravatal (25%). Houve predominou do sexo masculino (60%), média de idade de 51,7 (±15,6) anos, nível de escolaridade fundamental (60%), início das atividades na infância (75%), contato ocupacional (80%) e tempo na propriedade de mais de cinco anos (90%). Predominou o consumo de leite não pasteurizado (90%), leite fervido (89%), queijo fresco (91% e alimentos com queijo (92%). Predominou a ordenha manual (74%), contato com placenta ou feto abortado (54%), não separar as vacas abortivas do rebanho (88%) e a não utilização de Equipamentos de Proteção Individual (EPI) (80%). Nos participantes soropositivos, predominou os sintomas perda de peso (19%), febre intermitente (17%) e sudorese profusa (15%%). Foram incluídas 70 propriedades com mediana de rebanho de 20 animais, predomínio de pequenos criadores (57%), compostos por fêmeas (79%) e criação de outra espécie animal susceptível à brucelose (80%), especialmente cães (60%). Conclusão: Conclui-se que a soroprevalência da brucelose é elevada em relação a outros estudos realizados no Brasil e os sintomas inespecíficos dificultam a suspeita diagnóstica. Uma abordagem com a interação entre a saúde animal e humana pode reduzir o risco de disseminação e melhorar o diagnóstico da brucelose em seres humanos.Prophiro, Josiane SomarivaLopes, Cyntia Michielin2019-03-21T18:32:56Z2020-11-26T21:01:58Z2019-03-21T18:32:56Z2020-11-26T21:01:58Z2018info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesis83 f.application/pdfhttps://repositorio.animaeducacao.com.br/handle/ANIMA/3122Programa de Pós-Graduação em Ciência da SaúdePrograma de Pós-Graduação em Ciências da SaúdeAttribution-NonCommercial-NoDerivs 3.0 Brazilhttp://creativecommons.org/licenses/by-nc-nd/3.0/br/info:eu-repo/semantics/openAccessporreponame:Repositório Universitário da Ânima (RUNA)instname:Ânima Educaçãoinstacron:Ânima2020-12-01T16:48:54Zoai:repositorio.animaeducacao.com.br:ANIMA/3122Repositório InstitucionalPRIhttps://repositorio.animaeducacao.com.br/oai/requestcontato@animaeducacao.com.bropendoar:2020-12-01T16:48:54Repositório Universitário da Ânima (RUNA) - Ânima Educaçãofalse
dc.title.none.fl_str_mv Investigação Epidemiológica de casos de brucelose humana no sul de Santa Catarina
Epidemiological investigation of cases of human brucellosis in southern Santa Catarina
title Investigação Epidemiológica de casos de brucelose humana no sul de Santa Catarina
spellingShingle Investigação Epidemiológica de casos de brucelose humana no sul de Santa Catarina
Lopes, Cyntia Michielin
Brucella abortus
Zoonose
Fatores de risco
Saúde Pública
title_short Investigação Epidemiológica de casos de brucelose humana no sul de Santa Catarina
title_full Investigação Epidemiológica de casos de brucelose humana no sul de Santa Catarina
title_fullStr Investigação Epidemiológica de casos de brucelose humana no sul de Santa Catarina
title_full_unstemmed Investigação Epidemiológica de casos de brucelose humana no sul de Santa Catarina
title_sort Investigação Epidemiológica de casos de brucelose humana no sul de Santa Catarina
author Lopes, Cyntia Michielin
author_facet Lopes, Cyntia Michielin
author_role author
dc.contributor.none.fl_str_mv Prophiro, Josiane Somariva
dc.contributor.author.fl_str_mv Lopes, Cyntia Michielin
dc.subject.por.fl_str_mv Brucella abortus
Zoonose
Fatores de risco
Saúde Pública
topic Brucella abortus
Zoonose
Fatores de risco
Saúde Pública
description Introduction: Brucellosis is a zoonotic disease, acquired through direct or indirect contact with infected animals. In humans, the symptoms are non-specific and often confused with other infectious diseases. Objective: To verify the seroprevalence and risk factors associated with bovine brucellosis transmission to humans. Methods: A cross-sectional study carried was out in municipalities in the Southern Region of Santa Catarina state. Blood was collected to serum obtentions for laboratorial diagnosis using the Indirect Immunoenzymatic Assay (ELISA) method and a questionnaire was used to collect sociodemographic data and risk factors. Results: Among the 139 participants included in the study, the seroprevalence was 14.4%. Prevalence of seropositive individuals living in the municipalities of Gravatal (25%). There was predominance of males (60%), mean age of 51.7 (± 15.6) years, level of primary schooling (60%), beginning of childhood activities (75%), occupational contact (80%) and time on property for more than five years (90%). The prevalence of unpasteurised milk (90%), boiled milk (89%), fresh cheese (91% and food with cheese (92%) was predominant). Predominance was manual milking (74%), contact with aborted placenta or fetus (88%) and non-use of Personal Protective Equipment (PPE) (80%). In the seropositive participants, symptoms were predominant: weight loss (19%), intermittent fever (17%), Seventy (70%) and profuse sweating (15%) were included in the study, with a median herd of 20 animals, predominantly of small breeders (57%), females (79%) and breeding animals susceptible to brucellosis (80 %), especially dogs (60%). Conclusion: It is concluded that the seroprevalence of brucellosis is high in relation to other studies carried out in Brazil and the non-specific symptoms make diagnostic suspicion difficult. An approach to the interaction between animal and human health can reduce the risk of dissemination and improve the diagnosis of brucellosis in humans.
publishDate 2018
dc.date.none.fl_str_mv 2018
2019-03-21T18:32:56Z
2019-03-21T18:32:56Z
2020-11-26T21:01:58Z
2020-11-26T21:01:58Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
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dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv Programa de Pós-Graduação em Ciência da Saúde
dc.rights.driver.fl_str_mv Attribution-NonCommercial-NoDerivs 3.0 Brazil
http://creativecommons.org/licenses/by-nc-nd/3.0/br/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Attribution-NonCommercial-NoDerivs 3.0 Brazil
http://creativecommons.org/licenses/by-nc-nd/3.0/br/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 83 f.
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instacron:Ânima
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institution Ânima
reponame_str Repositório Universitário da Ânima (RUNA)
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repository.mail.fl_str_mv contato@animaeducacao.com.br
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