Associa??o do excesso de peso com gravidade em crian?as e adolescentes com covid-19: uma revis?o sistem?tica
Ano de defesa: | 2021 |
---|---|
Autor(a) principal: | |
Orientador(a): | |
Banca de defesa: | |
Tipo de documento: | Dissertação |
Tipo de acesso: | Acesso aberto |
Idioma: | por |
Instituição de defesa: |
Pontif?cia Universidade Cat?lica do Rio Grande do Sul
|
Programa de Pós-Graduação: |
Programa de P?s-Gradua??o em Medicina/Pediatria e Sa?de da Crian?a
|
Departamento: |
Escola de Medicina
|
País: |
Brasil
|
Palavras-chave em Português: | |
Palavras-chave em Inglês: | |
Área do conhecimento CNPq: | |
Link de acesso: | http://tede2.pucrs.br/tede2/handle/tede/9949 |
Resumo: | Background: 100 years ago, on a world scale, there was no tragedy similar to COVID-19, causing such serious health damage, not to mention economic and psychosocial harm. Concomitantly to this pandemic, in the child population there was already another pandemic wave in progress, being alerted by the WHO: childhood obesity. This condition of chronic inflammation causes a drop in the immune system and an increased susceptibility to infections. Numerous studies in adults have been carried out and describe obesity as an independent risk and prognostic factor for the severity of COVID-19, as well as for the need for ICU. Objective: To systematically review the literature on the relationship between overweight and the severity of COVID-19 in children and adolescents. Methods: This systematic review was developed following the PRISMA standards (Preferred Reporting Items for Systematic Review and Meta-Analysis), following the PICO eligibility criteria. The literature search was performed in September 2020, in the following databases: MEDLINE (via PubMed), Embase, Scopus, The Cochrane Library (Cochrane Database of Systematic Reviews and Cochrane Central Register of Controlled Trials (CENTRAL)), Web of Science, BVS / LILACS and SciELO. Registration was performed on the PROSPERO platform (International Prospective Registry of Systematic Reviews), under the registration number: CRD42021230686. Results: Of the 667 selected articles, 11 were included according to all agreed criteria, most of them being unicentric and American. In assessing the risk of bias and quality, following the criteria of the Newcastle-Ottawa Scale, eight studies achieved scores higher than 7. Only 5 studies sought to assess obesity and its relationship with worse outcomes (such as need for PICU, MV, tracheostomy, hospital readmission and mortality), and of these, only one article demonstrated this comorbidity as a prognostic factor for worse evolution of the COVID picture. Conclusion: There are few studies in the literature that seek to assess excess weight and its relationship with worse outcomes of COVID-19 in children and adolescents. Taking into account that there is already scientific evidence on this subject in adult patients, it is necessary to carry out more research in the pediatric age group. |
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Garcia, Pedro Celiny Ramoshttp://lattes.cnpq.br/0761993714239641http://lattes.cnpq.br/8546514638734778Kist, Mayara Lu?za Oliveira da Silva2021-10-28T18:09:57Z2021-08-27http://tede2.pucrs.br/tede2/handle/tede/9949Background: 100 years ago, on a world scale, there was no tragedy similar to COVID-19, causing such serious health damage, not to mention economic and psychosocial harm. Concomitantly to this pandemic, in the child population there was already another pandemic wave in progress, being alerted by the WHO: childhood obesity. This condition of chronic inflammation causes a drop in the immune system and an increased susceptibility to infections. Numerous studies in adults have been carried out and describe obesity as an independent risk and prognostic factor for the severity of COVID-19, as well as for the need for ICU. Objective: To systematically review the literature on the relationship between overweight and the severity of COVID-19 in children and adolescents. Methods: This systematic review was developed following the PRISMA standards (Preferred Reporting Items for Systematic Review and Meta-Analysis), following the PICO eligibility criteria. The literature search was performed in September 2020, in the following databases: MEDLINE (via PubMed), Embase, Scopus, The Cochrane Library (Cochrane Database of Systematic Reviews and Cochrane Central Register of Controlled Trials (CENTRAL)), Web of Science, BVS / LILACS and SciELO. Registration was performed on the PROSPERO platform (International Prospective Registry of Systematic Reviews), under the registration number: CRD42021230686. Results: Of the 667 selected articles, 11 were included according to all agreed criteria, most of them being unicentric and American. In assessing the risk of bias and quality, following the criteria of the Newcastle-Ottawa Scale, eight studies achieved scores higher than 7. Only 5 studies sought to assess obesity and its relationship with worse outcomes (such as need for PICU, MV, tracheostomy, hospital readmission and mortality), and of these, only one article demonstrated this comorbidity as a prognostic factor for worse evolution of the COVID picture. Conclusion: There are few studies in the literature that seek to assess excess weight and its relationship with worse outcomes of COVID-19 in children and adolescents. Taking into account that there is already scientific evidence on this subject in adult patients, it is necessary to carry out more research in the pediatric age group.Introdu??o: H? 100 anos, em escala mundial, n?o houve nenhuma trag?dia parecida ao COVID-19, causando danos de sa?de t?o graves, sem mencionar agravos econ?micos e psicossociais. Concomitantemente a essa pandemia, na popula??o infantil j? havia outra onda pand?mica em andamento, sendo alertada pela OMS: a obesidade infantil. Essa condi??o de inflama??o cr?nica, gera queda do sistema imunol?gico e aumento a susceptibilidade de infec??es. In?meros estudos em adultos foram realizados e descreveram a obesidade como risco independente e fator progn?stico para severidade da COVID-19, bem como para necessidade de UTI. Objetivo: Revisar sistematicamente a literatura acerca da rela??o entre excesso de peso e a severidade da COVID-19 em crian?as e adolescentes. M?todos: Essa revis?o sistem?tica foi desenvolvida seguindo as normas PRISMA (Preferred Reporting Items for Systematic Review and Meta-Analyses), seguindo os crit?rios de elegibilidade PICO. A busca na literatura foi realizada em setembro de 2020, nas bases de dados: MEDLINE (via PubMed), Embase, Scopus, The Cochrane Library (Cochrane Database of Systematic Reviews e Cochrane Central Register of Controlled Trials (CENTRAL)), Web of Science, BVS / LILACS e SciELO. Foi realizado registro na plataforma PROSPERO (International Prospective Register of Systematic Reviews), sob o n?mero de registro: CRD42021230686. Resultados: Dos 667 artigos inicialmente selecionados, 11 foram inclu?dos conforme todos os crit?rios analisados, sendo em sua maioria unic?ntricos e americanos. Na avalia??o de risco de vi?s e qualidade, seguindo os crit?rios da Newcastle-Ottawa Scale, oito trabalhos atingiram notas maiores do que 7. Apenas 5 estudos buscaram avaliar a obesidade e sua rela??o com piores desfechos (como necessidade de UTIP, VM, traqueostomia, readmiss?o hospitalar e mortalidade), e destes apenas um encontrou evid?ncia estat?stica significativa para descrever esta comorbidade como fator progn?stico para piores evolu??es do quadro da COVID. Conclus?o: Existem poucos trabalhos na literatura que buscam avaliar o excesso de peso e a sua rela??o com piores desfechos da COVID-19 em crian?as e adolescentes. Levando em conta que j? h? evid?ncia cient?fica robusta a respeito do assunto em pacientes adultos, faz-se necess?ria a realiza??o de mais pesquisas na faixa et?ria pedi?trica.Submitted by PPG Pediatria e Sa?de da Crian?a (pediatria-pg@pucrs.br) on 2021-10-28T17:34:20Z No. of bitstreams: 1 Disserta??o Mayara Ap?s Banca.pdf: 1828538 bytes, checksum: fe826e09d91d245bb2988f9c51fffa1f (MD5)Approved for entry into archive by Sheila Dias (sheila.dias@pucrs.br) on 2021-10-28T18:06:42Z (GMT) No. of bitstreams: 1 Disserta??o Mayara Ap?s Banca.pdf: 1828538 bytes, checksum: fe826e09d91d245bb2988f9c51fffa1f (MD5)Made available in DSpace on 2021-10-28T18:09:57Z (GMT). No. of bitstreams: 1 Disserta??o Mayara Ap?s Banca.pdf: 1828538 bytes, checksum: fe826e09d91d245bb2988f9c51fffa1f (MD5) Previous issue date: 2021-08-27Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior - CAPESapplication/pdfhttp://tede2.pucrs.br:80/tede2/retrieve/182506/DIS_MAYARA_LUIZA_OLIVEIRA_DA_SILVA_KIST_CONFIDENCIAL.pdf.jpgporPontif?cia Universidade Cat?lica do Rio Grande do SulPrograma de P?s-Gradua??o em Medicina/Pediatria e Sa?de da Crian?aPUCRSBrasilEscola de MedicinaCOVID-19Corona-V?rusObesidade InfantilExcesso de PesoSobrepesoUnidade de Terapia Intensiva Pedi?tricaChild ObesityOverweightPediatric Intensive Care UnitCIENCIAS DA SAUDE::MEDICINAMEDICINA::SAUDE MATERNO-INFANTILAssocia??o do excesso de peso com gravidade em crian?as e adolescentes com covid-19: uma revis?o sistem?ticainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisTrabalho ser? publicado como artigo ou livro60 meses28/10/2026557290555552975733500500500600600-224747486637135387-969369452308786627-80674179539253457523590462550136975366info:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da PUC_RSinstname:Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)instacron:PUC_RSTHUMBNAILDIS_MAYARA_LUIZA_OLIVEIRA_DA_SILVA_KIST_CONFIDENCIAL.pdf.jpgDIS_MAYARA_LUIZA_OLIVEIRA_DA_SILVA_KIST_CONFIDENCIAL.pdf.jpgimage/jpeg4075http://tede2.pucrs.br/tede2/bitstream/tede/9949/3/DIS_MAYARA_LUIZA_OLIVEIRA_DA_SILVA_KIST_CONFIDENCIAL.pdf.jpg8921ae79bc69bf8c55336d295af99764MD53TEXTDIS_MAYARA_LUIZA_OLIVEIRA_DA_SILVA_KIST_CONFIDENCIAL.pdf.txtDIS_MAYARA_LUIZA_OLIVEIRA_DA_SILVA_KIST_CONFIDENCIAL.pdf.txttext/plain1070http://tede2.pucrs.br/tede2/bitstream/tede/9949/2/DIS_MAYARA_LUIZA_OLIVEIRA_DA_SILVA_KIST_CONFIDENCIAL.pdf.txt4e80901290f01c84d602e46dd8a61f4fMD52ORIGINALDIS_MAYARA_LUIZA_OLIVEIRA_DA_SILVA_KIST_CONFIDENCIAL.pdfDIS_MAYARA_LUIZA_OLIVEIRA_DA_SILVA_KIST_CONFIDENCIAL.pdfapplication/pdf780213http://tede2.pucrs.br/tede2/bitstream/tede/9949/1/DIS_MAYARA_LUIZA_OLIVEIRA_DA_SILVA_KIST_CONFIDENCIAL.pdfb66abda7f7a0de0c4a9f1a312abe9672MD51tede/99492021-10-28 21:00:24.571oai:tede2.pucrs.br:tede/9949Biblioteca Digital de Teses e Dissertaçõeshttp://tede2.pucrs.br/tede2/PRIhttps://tede2.pucrs.br/oai/requestbiblioteca.central@pucrs.br||opendoar:2021-10-28T23:00:24Biblioteca Digital de Teses e Dissertações da PUC_RS - Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)false |
dc.title.por.fl_str_mv |
Associa??o do excesso de peso com gravidade em crian?as e adolescentes com covid-19: uma revis?o sistem?tica |
title |
Associa??o do excesso de peso com gravidade em crian?as e adolescentes com covid-19: uma revis?o sistem?tica |
spellingShingle |
Associa??o do excesso de peso com gravidade em crian?as e adolescentes com covid-19: uma revis?o sistem?tica Kist, Mayara Lu?za Oliveira da Silva COVID-19 Corona-V?rus Obesidade Infantil Excesso de Peso Sobrepeso Unidade de Terapia Intensiva Pedi?trica Child Obesity Overweight Pediatric Intensive Care Unit CIENCIAS DA SAUDE::MEDICINA MEDICINA::SAUDE MATERNO-INFANTIL |
title_short |
Associa??o do excesso de peso com gravidade em crian?as e adolescentes com covid-19: uma revis?o sistem?tica |
title_full |
Associa??o do excesso de peso com gravidade em crian?as e adolescentes com covid-19: uma revis?o sistem?tica |
title_fullStr |
Associa??o do excesso de peso com gravidade em crian?as e adolescentes com covid-19: uma revis?o sistem?tica |
title_full_unstemmed |
Associa??o do excesso de peso com gravidade em crian?as e adolescentes com covid-19: uma revis?o sistem?tica |
title_sort |
Associa??o do excesso de peso com gravidade em crian?as e adolescentes com covid-19: uma revis?o sistem?tica |
author |
Kist, Mayara Lu?za Oliveira da Silva |
author_facet |
Kist, Mayara Lu?za Oliveira da Silva |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Garcia, Pedro Celiny Ramos |
dc.contributor.advisor1Lattes.fl_str_mv |
http://lattes.cnpq.br/0761993714239641 |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/8546514638734778 |
dc.contributor.author.fl_str_mv |
Kist, Mayara Lu?za Oliveira da Silva |
contributor_str_mv |
Garcia, Pedro Celiny Ramos |
dc.subject.por.fl_str_mv |
COVID-19 Corona-V?rus Obesidade Infantil Excesso de Peso Sobrepeso Unidade de Terapia Intensiva Pedi?trica |
topic |
COVID-19 Corona-V?rus Obesidade Infantil Excesso de Peso Sobrepeso Unidade de Terapia Intensiva Pedi?trica Child Obesity Overweight Pediatric Intensive Care Unit CIENCIAS DA SAUDE::MEDICINA MEDICINA::SAUDE MATERNO-INFANTIL |
dc.subject.eng.fl_str_mv |
Child Obesity Overweight Pediatric Intensive Care Unit |
dc.subject.cnpq.fl_str_mv |
CIENCIAS DA SAUDE::MEDICINA MEDICINA::SAUDE MATERNO-INFANTIL |
description |
Background: 100 years ago, on a world scale, there was no tragedy similar to COVID-19, causing such serious health damage, not to mention economic and psychosocial harm. Concomitantly to this pandemic, in the child population there was already another pandemic wave in progress, being alerted by the WHO: childhood obesity. This condition of chronic inflammation causes a drop in the immune system and an increased susceptibility to infections. Numerous studies in adults have been carried out and describe obesity as an independent risk and prognostic factor for the severity of COVID-19, as well as for the need for ICU. Objective: To systematically review the literature on the relationship between overweight and the severity of COVID-19 in children and adolescents. Methods: This systematic review was developed following the PRISMA standards (Preferred Reporting Items for Systematic Review and Meta-Analysis), following the PICO eligibility criteria. The literature search was performed in September 2020, in the following databases: MEDLINE (via PubMed), Embase, Scopus, The Cochrane Library (Cochrane Database of Systematic Reviews and Cochrane Central Register of Controlled Trials (CENTRAL)), Web of Science, BVS / LILACS and SciELO. Registration was performed on the PROSPERO platform (International Prospective Registry of Systematic Reviews), under the registration number: CRD42021230686. Results: Of the 667 selected articles, 11 were included according to all agreed criteria, most of them being unicentric and American. In assessing the risk of bias and quality, following the criteria of the Newcastle-Ottawa Scale, eight studies achieved scores higher than 7. Only 5 studies sought to assess obesity and its relationship with worse outcomes (such as need for PICU, MV, tracheostomy, hospital readmission and mortality), and of these, only one article demonstrated this comorbidity as a prognostic factor for worse evolution of the COVID picture. Conclusion: There are few studies in the literature that seek to assess excess weight and its relationship with worse outcomes of COVID-19 in children and adolescents. Taking into account that there is already scientific evidence on this subject in adult patients, it is necessary to carry out more research in the pediatric age group. |
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2021 |
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