Fatores de risco para o desenvolvimento do câncer colorretal - Um estudo de caso-controle
Ano de defesa: | 2020 |
---|---|
Autor(a) principal: | |
Orientador(a): | |
Banca de defesa: | , |
Tipo de documento: | Dissertação |
Tipo de acesso: | Acesso aberto |
Idioma: | por |
Instituição de defesa: |
Universidade Estadual da Paraíba
|
Programa de Pós-Graduação: |
Programa de Pós-Graduação em Saúde Pública - PPGSP
|
Departamento: |
Pró-Reitoria de Pós-Graduação e Pesquisa - PRPGP
|
País: |
Brasil
|
Palavras-chave em Português: | |
Palavras-chave em Inglês: | |
Área do conhecimento CNPq: | |
Link de acesso: | http://tede.bc.uepb.edu.br/jspui/handle/tede/4177 |
Resumo: | Introduction: Colorectal cancer (CRC) is the third most common and the second leading cause of cancer death, its incidence and mortality rate is increasing in Northeast Brazil. Studies have shown that lifestyle and diet are risk factors, but some of these points are still inconclusive. Objectives: To identify food groups and nutrients that are most associated with the occurrence of colon and rectal cancer or its prevention. Methods: Case-control study with 65 patients with colorectal cancer and 123 controls, with data obtained through interviews and medical records. Nutrient intake was calculated using the DietSys 4.0 software. Binary logistic regression hurts applied to generate models of factors that significantly changed the risk of colorectal cancer. Results: In the model of nutritional factors, the intake of vitamin E decreases the chance of CRC by 18.0% (OR = 0.820); 95% CI: 0.719-0.936) for each milligram ingested per week (p = 0.003). In a model of dietary components, the risk of CRC increased by 1.9% (OR = 1.002; 95% CI: 1,000-1,004) for each gram of processed meat intake per week (p = 0.015). Egg consumption decreased the flue by 0.1% per gram (OR = 0.999; 95% CI: 0.998-1,000; p = 0.026). The use of oil (including olive oil) in food decreased the chance by 0.2% (OR = 0.981; 95% CI: 0.970-0.993) each time it was consumed (p = 0.001). Alcohol consumption versus non-consumption increased the chance of CCR 2.994 (95% CI: 0.950 - 9.438) times (p = 0.061). In both models, smoking was positively associated with CCR. Conclusions: The consumption of processed meat, alcohol and smoking increased the risk of developing colorectal cancer. Vitamin E, eggs and fish contributed to the prevention of pathology. The consumption of vegetables, fruits and vegetables hurt more in the control group, while the consumption of red meat, chicken and processed meat was higher among patients with CRC. |
id |
UEPB_9d9b7648aa6e32022d571dbd936c6958 |
---|---|
oai_identifier_str |
oai:tede.bc.uepb.edu.br:tede/4177 |
network_acronym_str |
UEPB |
network_name_str |
Biblioteca Digital de Teses e Dissertações da UEPB |
repository_id_str |
|
spelling |
Weller, Mathias60098933302Medeiros, Carla Campos Muniz64135667449Gonçalves, Maria da Conceição Rodrigues2196102644906479524403Ribeiro, Radmila Raianni Alves2022-03-01T17:12:15Z2020-09-25RIBEIRO, Radmila Raianni Alves. Fatores de risco para o desenvolvimento do câncer colorretal - Um estudo de caso-controle. 2020. 77f. Dissertação (Programa de Pós-Graduação em Saúde Pública - PPGSP) - Universidade Estadual da Paraíba, Campina Grande, 2022.http://tede.bc.uepb.edu.br/jspui/handle/tede/4177Introduction: Colorectal cancer (CRC) is the third most common and the second leading cause of cancer death, its incidence and mortality rate is increasing in Northeast Brazil. Studies have shown that lifestyle and diet are risk factors, but some of these points are still inconclusive. Objectives: To identify food groups and nutrients that are most associated with the occurrence of colon and rectal cancer or its prevention. Methods: Case-control study with 65 patients with colorectal cancer and 123 controls, with data obtained through interviews and medical records. Nutrient intake was calculated using the DietSys 4.0 software. Binary logistic regression hurts applied to generate models of factors that significantly changed the risk of colorectal cancer. Results: In the model of nutritional factors, the intake of vitamin E decreases the chance of CRC by 18.0% (OR = 0.820); 95% CI: 0.719-0.936) for each milligram ingested per week (p = 0.003). In a model of dietary components, the risk of CRC increased by 1.9% (OR = 1.002; 95% CI: 1,000-1,004) for each gram of processed meat intake per week (p = 0.015). Egg consumption decreased the flue by 0.1% per gram (OR = 0.999; 95% CI: 0.998-1,000; p = 0.026). The use of oil (including olive oil) in food decreased the chance by 0.2% (OR = 0.981; 95% CI: 0.970-0.993) each time it was consumed (p = 0.001). Alcohol consumption versus non-consumption increased the chance of CCR 2.994 (95% CI: 0.950 - 9.438) times (p = 0.061). In both models, smoking was positively associated with CCR. Conclusions: The consumption of processed meat, alcohol and smoking increased the risk of developing colorectal cancer. Vitamin E, eggs and fish contributed to the prevention of pathology. The consumption of vegetables, fruits and vegetables hurt more in the control group, while the consumption of red meat, chicken and processed meat was higher among patients with CRC.Introdução: O câncer colorretal (CCR) é o terceiro tipo mais comum e a segunda causa de morte de câncer, a sua incidência e taxa de mortalidade está aumentando no Nordeste do Brasil. Estudos têm demonstrado que o estilo de vida e a alimentação são fatores de risco, mas alguns desses pontos ainda são inconclusivos. Objetivos: Identificar, através do questionário, prováveis causas de cêncer colorretal. Métodos: Estudo de caso-controle com 64 pacientes portadores do câncer colorretal e 123 controles, com dados obtidos através de entrevistas e prontuários médicos. A ingestão de nutrientes foi calculada pelo software DietSys 4.0. A regressão logística binária foi aplicada para gerar modelos de fatores que modificaram significativamente o risco de câncer colorretal. Resultados: No modelo de fatores nutricionais, a ingestão de vitamina E diminui a chance de CCR em 18,0% (OR = 0,820); IC 95%: 0,719-0,936) para cada miligrama ingerido por semana (p=0,003). Em um modelo de componentes dietéticos, o risco de CCR aumentou 1,9% (OR = 1,002; IC 95%: 1,000-1,004) para cada grama de ingestão de carne processada por semana (p=0,015). O consumo de ovos diminuiu a chande em 0,1% por grama (OR = 0,999; IC 95%: 0,998-1,000; p = 0,026). O uso de óleo (incluindo azeite de oliva) na comida diminuiu a chance em 0,2% (OR = 0,981; IC 95%: 0,970-0,993) a cada vez que consumido (p = 0,001). O consumo de álcool versus o não consumo aumentou a chance de CCR 2,994 (IC 95%: 0,950 – 9,438) vezes (p = 0,061). Em ambos os modelos, o tabagismo associou-se positivamente ao CCR. Conclusões: O consumo do tabagismo aumentou o risco de desenvolver o câncer colorretal. A vitamina E e ovos contribuíram para a prevenção da patologia. O consumo de vegetais, frutas e legumes dói maior no grupo controle, enquanto o consumo de carne vermelha, frango e carne processada foram maiores entre os pacientes com CCR.Submitted by Jean Medeiros (jeanletras@uepb.edu.br) on 2022-02-28T12:06:19Z No. of bitstreams: 1 PDF - Radmila Raianni Alves Ribeiro.pdf: 3492931 bytes, checksum: d60ab96e101ecc83bf11633d6bc58c40 (MD5)Approved for entry into archive by Secta BC (secta.csu.bc@uepb.edu.br) on 2022-03-01T16:52:26Z (GMT) No. of bitstreams: 1 PDF - Radmila Raianni Alves Ribeiro.pdf: 3492931 bytes, checksum: d60ab96e101ecc83bf11633d6bc58c40 (MD5)Made available in DSpace on 2022-03-01T17:12:15Z (GMT). No. of bitstreams: 1 PDF - Radmila Raianni Alves Ribeiro.pdf: 3492931 bytes, checksum: d60ab96e101ecc83bf11633d6bc58c40 (MD5) Previous issue date: 2020-09-25application/pdfporUniversidade Estadual da ParaíbaPrograma de Pós-Graduação em Saúde Pública - PPGSPUEPBBrasilPró-Reitoria de Pós-Graduação e Pesquisa - PRPGPEpidemiologiaFatores de riscoCâncer colorretalNeoplasia de intestinoEpidemiologyColorectal cancerRisk factorsBowel cancerSAUDE COLETIVA::SAUDE PUBLICAFatores de risco para o desenvolvimento do câncer colorretal - Um estudo de caso-controleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesis-4979121372796375736006006005248714503811102783112649244584600979info:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da UEPBinstname:Universidade Estadual da Paraíba (UEPB)instacron:UEPBORIGINALPDF - Radmila Raianni Alves Ribeiro.pdfPDF - Radmila Raianni Alves Ribeiro.pdfapplication/pdf3492931http://tede.bc.uepb.edu.br/jspui/bitstream/tede/4177/2/PDF+-+Radmila+Raianni+Alves+Ribeiro.pdfd60ab96e101ecc83bf11633d6bc58c40MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-81960http://tede.bc.uepb.edu.br/jspui/bitstream/tede/4177/1/license.txt6052ae61e77222b2086e666b7ae213ceMD51tede/41772022-03-01 14:12:15.125oai:tede.bc.uepb.edu.br: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Biblioteca Digital de Teses e Dissertaçõeshttp://tede.bc.uepb.edu.br/jspui/PUBhttp://tede.bc.uepb.edu.br/oai/requestbc@uepb.edu.br||opendoar:2022-03-01T17:12:15Biblioteca Digital de Teses e Dissertações da UEPB - Universidade Estadual da Paraíba (UEPB)false |
dc.title.por.fl_str_mv |
Fatores de risco para o desenvolvimento do câncer colorretal - Um estudo de caso-controle |
title |
Fatores de risco para o desenvolvimento do câncer colorretal - Um estudo de caso-controle |
spellingShingle |
Fatores de risco para o desenvolvimento do câncer colorretal - Um estudo de caso-controle Ribeiro, Radmila Raianni Alves Epidemiologia Fatores de risco Câncer colorretal Neoplasia de intestino Epidemiology Colorectal cancer Risk factors Bowel cancer SAUDE COLETIVA::SAUDE PUBLICA |
title_short |
Fatores de risco para o desenvolvimento do câncer colorretal - Um estudo de caso-controle |
title_full |
Fatores de risco para o desenvolvimento do câncer colorretal - Um estudo de caso-controle |
title_fullStr |
Fatores de risco para o desenvolvimento do câncer colorretal - Um estudo de caso-controle |
title_full_unstemmed |
Fatores de risco para o desenvolvimento do câncer colorretal - Um estudo de caso-controle |
title_sort |
Fatores de risco para o desenvolvimento do câncer colorretal - Um estudo de caso-controle |
author |
Ribeiro, Radmila Raianni Alves |
author_facet |
Ribeiro, Radmila Raianni Alves |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Weller, Mathias |
dc.contributor.advisor1ID.fl_str_mv |
60098933302 |
dc.contributor.referee1.fl_str_mv |
Medeiros, Carla Campos Muniz |
dc.contributor.referee1ID.fl_str_mv |
64135667449 |
dc.contributor.referee2.fl_str_mv |
Gonçalves, Maria da Conceição Rodrigues |
dc.contributor.referee2ID.fl_str_mv |
21961026449 |
dc.contributor.authorID.fl_str_mv |
06479524403 |
dc.contributor.author.fl_str_mv |
Ribeiro, Radmila Raianni Alves |
contributor_str_mv |
Weller, Mathias Medeiros, Carla Campos Muniz Gonçalves, Maria da Conceição Rodrigues |
dc.subject.por.fl_str_mv |
Epidemiologia Fatores de risco Câncer colorretal Neoplasia de intestino |
topic |
Epidemiologia Fatores de risco Câncer colorretal Neoplasia de intestino Epidemiology Colorectal cancer Risk factors Bowel cancer SAUDE COLETIVA::SAUDE PUBLICA |
dc.subject.eng.fl_str_mv |
Epidemiology Colorectal cancer Risk factors Bowel cancer |
dc.subject.cnpq.fl_str_mv |
SAUDE COLETIVA::SAUDE PUBLICA |
description |
Introduction: Colorectal cancer (CRC) is the third most common and the second leading cause of cancer death, its incidence and mortality rate is increasing in Northeast Brazil. Studies have shown that lifestyle and diet are risk factors, but some of these points are still inconclusive. Objectives: To identify food groups and nutrients that are most associated with the occurrence of colon and rectal cancer or its prevention. Methods: Case-control study with 65 patients with colorectal cancer and 123 controls, with data obtained through interviews and medical records. Nutrient intake was calculated using the DietSys 4.0 software. Binary logistic regression hurts applied to generate models of factors that significantly changed the risk of colorectal cancer. Results: In the model of nutritional factors, the intake of vitamin E decreases the chance of CRC by 18.0% (OR = 0.820); 95% CI: 0.719-0.936) for each milligram ingested per week (p = 0.003). In a model of dietary components, the risk of CRC increased by 1.9% (OR = 1.002; 95% CI: 1,000-1,004) for each gram of processed meat intake per week (p = 0.015). Egg consumption decreased the flue by 0.1% per gram (OR = 0.999; 95% CI: 0.998-1,000; p = 0.026). The use of oil (including olive oil) in food decreased the chance by 0.2% (OR = 0.981; 95% CI: 0.970-0.993) each time it was consumed (p = 0.001). Alcohol consumption versus non-consumption increased the chance of CCR 2.994 (95% CI: 0.950 - 9.438) times (p = 0.061). In both models, smoking was positively associated with CCR. Conclusions: The consumption of processed meat, alcohol and smoking increased the risk of developing colorectal cancer. Vitamin E, eggs and fish contributed to the prevention of pathology. The consumption of vegetables, fruits and vegetables hurt more in the control group, while the consumption of red meat, chicken and processed meat was higher among patients with CRC. |
publishDate |
2020 |
dc.date.issued.fl_str_mv |
2020-09-25 |
dc.date.accessioned.fl_str_mv |
2022-03-01T17:12:15Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
format |
masterThesis |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
RIBEIRO, Radmila Raianni Alves. Fatores de risco para o desenvolvimento do câncer colorretal - Um estudo de caso-controle. 2020. 77f. Dissertação (Programa de Pós-Graduação em Saúde Pública - PPGSP) - Universidade Estadual da Paraíba, Campina Grande, 2022. |
dc.identifier.uri.fl_str_mv |
http://tede.bc.uepb.edu.br/jspui/handle/tede/4177 |
identifier_str_mv |
RIBEIRO, Radmila Raianni Alves. Fatores de risco para o desenvolvimento do câncer colorretal - Um estudo de caso-controle. 2020. 77f. Dissertação (Programa de Pós-Graduação em Saúde Pública - PPGSP) - Universidade Estadual da Paraíba, Campina Grande, 2022. |
url |
http://tede.bc.uepb.edu.br/jspui/handle/tede/4177 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.program.fl_str_mv |
-497912137279637573 |
dc.relation.confidence.fl_str_mv |
600 600 600 |
dc.relation.department.fl_str_mv |
524871450381110278 |
dc.relation.cnpq.fl_str_mv |
3112649244584600979 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Estadual da Paraíba |
dc.publisher.program.fl_str_mv |
Programa de Pós-Graduação em Saúde Pública - PPGSP |
dc.publisher.initials.fl_str_mv |
UEPB |
dc.publisher.country.fl_str_mv |
Brasil |
dc.publisher.department.fl_str_mv |
Pró-Reitoria de Pós-Graduação e Pesquisa - PRPGP |
publisher.none.fl_str_mv |
Universidade Estadual da Paraíba |
dc.source.none.fl_str_mv |
reponame:Biblioteca Digital de Teses e Dissertações da UEPB instname:Universidade Estadual da Paraíba (UEPB) instacron:UEPB |
instname_str |
Universidade Estadual da Paraíba (UEPB) |
instacron_str |
UEPB |
institution |
UEPB |
reponame_str |
Biblioteca Digital de Teses e Dissertações da UEPB |
collection |
Biblioteca Digital de Teses e Dissertações da UEPB |
bitstream.url.fl_str_mv |
http://tede.bc.uepb.edu.br/jspui/bitstream/tede/4177/2/PDF+-+Radmila+Raianni+Alves+Ribeiro.pdf http://tede.bc.uepb.edu.br/jspui/bitstream/tede/4177/1/license.txt |
bitstream.checksum.fl_str_mv |
d60ab96e101ecc83bf11633d6bc58c40 6052ae61e77222b2086e666b7ae213ce |
bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 |
repository.name.fl_str_mv |
Biblioteca Digital de Teses e Dissertações da UEPB - Universidade Estadual da Paraíba (UEPB) |
repository.mail.fl_str_mv |
bc@uepb.edu.br|| |
_version_ |
1800227521462009856 |