O uso de dexametasona e etoricoxibe para a prevenção e controle da dor pós-operatória após cirurgia periodontal

• Ano de defesa: 2009
• Autor(a) principal: Steffens, João Paulo
• Orientador(a): Pilatti, Gibson Luiz
• Banca de defesa: Santos, Fábio André dos , Deliberador, Tatiana Miranda
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: UNIVERSIDADE ESTADUAL DE PONTA GROSSA
• Programa de Pós-Graduação: Programa de Pós-Graduação em Odontologia
• Departamento: Clinica Integrada, Dentística Restauradora e Periodontia
• País: BR
• Palavras-chave em Português: analgesia; pré-Medicação; medição da dor
• Palavras-chave em Inglês: analgesia; pre-medication; pain measurement
• Área do conhecimento CNPq: CNPQ::CIENCIAS DA SAUDE::ODONTOLOGIA
• Link de acesso: http://tede2.uepg.br/jspui/handle/prefix/1756

Several anti-inflammatory drugs have been used to reduce pain and discomfort after periodontal surgeries. The purpose of this study was to evaluate the efficacy of etoricoxib and dexamethasone on pain prevention after open flap debridement surgery. For this prospective, double-masked, cross-over, placebo-controlled randomized clinical trial, open flap debridement surgeries were performed on 15 patients who presented chronic periodontitis after nonsurgical periodontal therapy at three sextants. Each patient was submitted to three surgical procedures with intervals of 30 days and received one of the premedication protocols one hour before surgery: G1- placebo; G2- 8 mg dexamethasone; G3- 90 mg etoricoxib. Pain intensity and discomfort were evaluated by visual analog scale (VAS), 101-point numerical rate scale (NRS-101) and a 4-point verbal rate scale (VRS-4) during 8 hours after surgery and three times a day on the 3 following days. Data were submitted to appropriate statistical analysis. The results demonstrated that G2 and G3 presented reduced postoperative pain intensity levels than G1. There were statistically significant differences at 4, 5, 6, 7 and 8 hour-period after surgery (Friedman test; p<0.05). Besides, rescue medication intake was significantly lower for G2 and G3 than for G1 (p<0.05). It was concluded that the adoption of a preemptive medication protocol using etoricoxib or dexamethasone may be considered effective on pain prevention after open flap debridement surgeries.