Efeito do néctar de camu-camu (Myrciaria dubia (Kunth) McVaugh) nos níveis séricos de colesterol, triglicerídeos e glicose em adultos

Detalhes bibliográficos
Ano de defesa: 2012
Autor(a) principal: Gonçalves, Flávia Amaro lattes
Orientador(a): Yuyama, Lucia Kiyoko Ozaki lattes
Banca de defesa: Não Informado pela instituição
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Federal do Amazonas
Programa de Pós-Graduação: Programa de Pós-graduação em Ciências de Alimentos
Departamento: Faculdade de Ciências Farmacêuticas
País: Brasil
Palavras-chave em Português:
Área do conhecimento CNPq:
Link de acesso: http://tede.ufam.edu.br/handle/tede/5169
Resumo: The chronic diseases have increased considerably, currently representing one of the most important public health problems. In this scenario, preventive measures have a prominent place where it should be combined guidelines for reducing cardiovascular disease, such as encouraging a healthy diet rich in fruits and vegetables. The Amazon region holds various vegetative species that have high potential for industrial use and can contribute to the health of the population, among which is the camu-camu is a fruit that stands out for its remarkable vitamin C. Therefore, this study aimed to evaluate the effect of the camu-camu (Myrciaria dubia (Kunth) McVaugh) in serum cholesterol, triglycerides and glucose in adults. The camu-camu fruit were acquired at the stage of commercial maturity, Yurican on the farm, located at km 100 of the AM-010 highway, in the city of Rio Preto da Eva (Amazonas). Are pulped for formulating the nectar and then stored in sterile bottles properly. Participants were 17 adults normocholesterolemic. After selecting the sample, subjects were divided into two groups: the intervention group (IG) received the camu-camu and the second group, the control group (CG) received vitamica C synthetic, both at a concentration of 500 mg of ascorbic for 15 days. Biochemical tests were performed at the beginning and end of the intervention in order to check for possible interferences in total cholesterol and fractions, triglycerides and glucose. After fifteen days of consumption of the camu-camu, GI presented a reduction of 4.0% in average total cholesterol. In the control group the mean initial cholesterol was found to be 145 mg / dL and end of 148 mg / dL but no significant difference between the study groups. Regarding the concentrations of HDL-cholesterol, there was no significant difference between treatments (p> 0.05), regardless of the type of intervention, but the CG showed a trend of 11% increase in HDL-cholesterol. As for the plasma concentration of LDL-cholesterol was observed in GI a reduction of 2.4% in GC and there was an increase of 10.8%, but these values do not differ statistically. The present study showed a tendency to decrease triglyceride levels in both groups, a decrease of 10.2% for GI and 25.8% for GC. The glucose concentration decreased by 2.4% for GI and an increase of 10.8% for the GC, but with no significant difference between groups (p> 0.05). It is concluded that ingestion of the camu-camu result showed more efficient when compared to synthetic vitamin C. The 500 mg dose of vitamin C may be established as reference for future studies in patients with hypercholesterolemia or have an inadequate intake of the vitamin.
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spelling Yuyama, Lucia Kiyoko Ozaki83375716834http://lattes.cnpq.br/2466776830720833Souza, Francisca das Chagas do Amaral43694705287http://lattes.cnpq.br/428109383739662171935207253flavia_amaro2@hotmail.com(92) 98118-7479Controle DD/UFAM: 244/2016http://lattes.cnpq.br/7784594223009567Gonçalves, Flávia Amaro2016-08-29T13:02:11Z2012-08-27GONÇALVES, Flávia Amaro. Efeito do néctar de camu-camu (Myrciaria dubia (Kunth) McVaugh) nos níveis séricos de colesterol, triglicerídeos e glicose em adultos. 2012. 73 f. Dissertação (Mestrado em Ciência de Alimentos) - Universidade Federal do Amazonas, Manaus, 2012.http://tede.ufam.edu.br/handle/tede/5169The chronic diseases have increased considerably, currently representing one of the most important public health problems. In this scenario, preventive measures have a prominent place where it should be combined guidelines for reducing cardiovascular disease, such as encouraging a healthy diet rich in fruits and vegetables. The Amazon region holds various vegetative species that have high potential for industrial use and can contribute to the health of the population, among which is the camu-camu is a fruit that stands out for its remarkable vitamin C. Therefore, this study aimed to evaluate the effect of the camu-camu (Myrciaria dubia (Kunth) McVaugh) in serum cholesterol, triglycerides and glucose in adults. The camu-camu fruit were acquired at the stage of commercial maturity, Yurican on the farm, located at km 100 of the AM-010 highway, in the city of Rio Preto da Eva (Amazonas). Are pulped for formulating the nectar and then stored in sterile bottles properly. Participants were 17 adults normocholesterolemic. After selecting the sample, subjects were divided into two groups: the intervention group (IG) received the camu-camu and the second group, the control group (CG) received vitamica C synthetic, both at a concentration of 500 mg of ascorbic for 15 days. Biochemical tests were performed at the beginning and end of the intervention in order to check for possible interferences in total cholesterol and fractions, triglycerides and glucose. After fifteen days of consumption of the camu-camu, GI presented a reduction of 4.0% in average total cholesterol. In the control group the mean initial cholesterol was found to be 145 mg / dL and end of 148 mg / dL but no significant difference between the study groups. Regarding the concentrations of HDL-cholesterol, there was no significant difference between treatments (p> 0.05), regardless of the type of intervention, but the CG showed a trend of 11% increase in HDL-cholesterol. As for the plasma concentration of LDL-cholesterol was observed in GI a reduction of 2.4% in GC and there was an increase of 10.8%, but these values do not differ statistically. The present study showed a tendency to decrease triglyceride levels in both groups, a decrease of 10.2% for GI and 25.8% for GC. The glucose concentration decreased by 2.4% for GI and an increase of 10.8% for the GC, but with no significant difference between groups (p> 0.05). It is concluded that ingestion of the camu-camu result showed more efficient when compared to synthetic vitamin C. The 500 mg dose of vitamin C may be established as reference for future studies in patients with hypercholesterolemia or have an inadequate intake of the vitamin.As doenças crônicas não transmissíveis vêm aumentando consideravelmente, representando atualmente um dos mais importantes problemas de saúde pública. Neste cenário, as medidas preventivas ocupam lugar de destaque onde devem ser combinadas orientações para a redução das doenças cardiovasculares, como exemplo o incentivo a uma alimentação saudável rica em frutas e hortaliças. A região Amazônica é detentora de diversas espécies vegetativas que possuem alto potencial para aproveitamento industrial e que podem contribuir com a saúde da população, dentre os quais encontra-se o camu-camu que é um fruto que destaca-se pelo seu notável teor de vitamina C. Sendo assim, o presente estudo teve como objetivo avaliar o efeito do néctar de camu-camu, (Myrciaria dubia (Kunth) McVaugh) nos níveis séricos de colesterol, triglicerídeos e glicose em adultos. Os frutos de camu-camu foram adquiridos no estágio de maturação comercial, na fazenda Yurican, localizada no km 100 da Rodovia AM-010, no município de Rio Preto da Eva (Amazonas). Foram despolpados para a formulação do néctar e em seguida armazenados em garrafas devidamente esterilizadas. Participaram da pesquisa 17 adultos normocolesterolêmicos. Após a seleção da amostra, os indivíduos foram distribuídos em dois grupos: grupo intervenção (GI) que recebeu néctar de camu-camu e o segundo grupo, grupo controle (GC), que recebeu vitamica C sintética, ambos na concentração de 500 mg de ácido ascórbico durante 15 dias. Foram realizados exames bioquímicos no início e ao final da intervenção com a finalidade de verificar as possíveis interferências no colesterol total e frações, glicemia e triglicerídeos. Após quinze dias de consumo do néctar de camu-camu, o GI apresentou uma redução de 4,0% no valor médio de colesterol total. No grupo GC o valor médio inicial de colesterol encontrado foi de 145 mg/dL e final de 148 mg/dL porém não houve diferença significativa entre os grupos de estudo. Em relação às concentrações de HDL-colesterol, não se observou diferença significativa entre os tratamentos (p>0,05), independentemente do tipo de intervenção, porém o GC apresentou uma tendência de 11% no aumento de HDL-colesterol. Quanto à concentração plasmática de LDL-colesterol foi observado no GI uma redução de 2,4% e no GC houve um aumento de 10,8%, porém estes valores não se diferenciam estatisticamente. A presente pesquisa apresentou uma tendência à diminuição dos níveis de triglicerídeos em ambos os grupos, apresentando uma redução de 10,2% para o GI e 25,8% para o GC. A concentração de glicose apresentou uma redução de 2,4% para o GI e um aumento de 10,8% para o GC, porém sem diferença significativa entre os grupos (p>0,05). Conclui-se que a ingestão do néctar de camu-camu apresentou resultado mais eficiente quando comparado a vitamina C sintética. A dose de 500 mg de vitamina C pode ser estabelecida como referência para futuros estudos em indivíduos hipercolesterolêmicos ou que tenham uma inadequação do consumo desta vitamina.Submitted by Gabriele Rodrigues (gabriele_r.valentim@hotmail.com) on 2016-08-26T14:25:43Z No. of bitstreams: 1 Dissertação - Flávia Amaro Gonçalves.pdf: 862305 bytes, checksum: 52409a151c822f8e352523d958f7aa90 (MD5)Approved for entry into archive by Divisão de Documentação/BC Biblioteca Central (ddbc@ufam.edu.br) on 2016-08-29T12:57:57Z (GMT) No. of bitstreams: 1 Dissertação - Flávia Amaro Gonçalves.pdf: 862305 bytes, checksum: 52409a151c822f8e352523d958f7aa90 (MD5)Approved for entry into archive by Divisão de Documentação/BC Biblioteca Central (ddbc@ufam.edu.br) on 2016-08-29T13:02:11Z (GMT) No. of bitstreams: 1 Dissertação - Flávia Amaro Gonçalves.pdf: 862305 bytes, checksum: 52409a151c822f8e352523d958f7aa90 (MD5)Made available in DSpace on 2016-08-29T13:02:11Z (GMT). No. of bitstreams: 1 Dissertação - Flávia Amaro Gonçalves.pdf: 862305 bytes, checksum: 52409a151c822f8e352523d958f7aa90 (MD5) Previous issue date: 2012-08-27CAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superiorapplication/pdfhttp://tede.ufam.edu.br//retrieve/13554/Disserta%c3%a7%c3%a3o%20-%20Fl%c3%a1via%20Amaro%20Gon%c3%a7alves.pdf.jpgporUniversidade Federal do AmazonasPrograma de Pós-graduação em Ciências de AlimentosUFAMBrasilFaculdade de Ciências FarmacêuticasFruto amazônicoPerfil lipídicoSaúde públicaCamu-camuCIÊNCIAS AGRÁRIAS: CIÊNCIA E TECNOLOGIA DE ALIMENTOS: CIÊNCIA DE ALIMENTOSEfeito do néctar de camu-camu (Myrciaria dubia (Kunth) McVaugh) nos níveis séricos de colesterol, triglicerídeos e glicose em adultosinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesis-6333686939513663750600500-8773172453627126821info:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da UFAMinstname:Universidade Federal do Amazonas (UFAM)instacron:UFAMLICENSElicense.txtlicense.txttext/plain; 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dc.title.por.fl_str_mv Efeito do néctar de camu-camu (Myrciaria dubia (Kunth) McVaugh) nos níveis séricos de colesterol, triglicerídeos e glicose em adultos
title Efeito do néctar de camu-camu (Myrciaria dubia (Kunth) McVaugh) nos níveis séricos de colesterol, triglicerídeos e glicose em adultos
spellingShingle Efeito do néctar de camu-camu (Myrciaria dubia (Kunth) McVaugh) nos níveis séricos de colesterol, triglicerídeos e glicose em adultos
Gonçalves, Flávia Amaro
Fruto amazônico
Perfil lipídico
Saúde pública
Camu-camu
CIÊNCIAS AGRÁRIAS: CIÊNCIA E TECNOLOGIA DE ALIMENTOS: CIÊNCIA DE ALIMENTOS
title_short Efeito do néctar de camu-camu (Myrciaria dubia (Kunth) McVaugh) nos níveis séricos de colesterol, triglicerídeos e glicose em adultos
title_full Efeito do néctar de camu-camu (Myrciaria dubia (Kunth) McVaugh) nos níveis séricos de colesterol, triglicerídeos e glicose em adultos
title_fullStr Efeito do néctar de camu-camu (Myrciaria dubia (Kunth) McVaugh) nos níveis séricos de colesterol, triglicerídeos e glicose em adultos
title_full_unstemmed Efeito do néctar de camu-camu (Myrciaria dubia (Kunth) McVaugh) nos níveis séricos de colesterol, triglicerídeos e glicose em adultos
title_sort Efeito do néctar de camu-camu (Myrciaria dubia (Kunth) McVaugh) nos níveis séricos de colesterol, triglicerídeos e glicose em adultos
author Gonçalves, Flávia Amaro
author_facet Gonçalves, Flávia Amaro
author_role author
dc.contributor.advisor1.fl_str_mv Yuyama, Lucia Kiyoko Ozaki
dc.contributor.advisor1ID.fl_str_mv 83375716834
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/2466776830720833
dc.contributor.advisor-co1.fl_str_mv Souza, Francisca das Chagas do Amaral
dc.contributor.advisor-co1ID.fl_str_mv 43694705287
dc.contributor.advisor-co1Lattes.fl_str_mv http://lattes.cnpq.br/4281093837396621
dc.contributor.authorID.fl_str_mv 71935207253
flavia_amaro2@hotmail.com
(92) 98118-7479
Controle DD/UFAM: 244/2016
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/7784594223009567
dc.contributor.author.fl_str_mv Gonçalves, Flávia Amaro
contributor_str_mv Yuyama, Lucia Kiyoko Ozaki
Souza, Francisca das Chagas do Amaral
dc.subject.por.fl_str_mv Fruto amazônico
Perfil lipídico
Saúde pública
Camu-camu
topic Fruto amazônico
Perfil lipídico
Saúde pública
Camu-camu
CIÊNCIAS AGRÁRIAS: CIÊNCIA E TECNOLOGIA DE ALIMENTOS: CIÊNCIA DE ALIMENTOS
dc.subject.cnpq.fl_str_mv CIÊNCIAS AGRÁRIAS: CIÊNCIA E TECNOLOGIA DE ALIMENTOS: CIÊNCIA DE ALIMENTOS
description The chronic diseases have increased considerably, currently representing one of the most important public health problems. In this scenario, preventive measures have a prominent place where it should be combined guidelines for reducing cardiovascular disease, such as encouraging a healthy diet rich in fruits and vegetables. The Amazon region holds various vegetative species that have high potential for industrial use and can contribute to the health of the population, among which is the camu-camu is a fruit that stands out for its remarkable vitamin C. Therefore, this study aimed to evaluate the effect of the camu-camu (Myrciaria dubia (Kunth) McVaugh) in serum cholesterol, triglycerides and glucose in adults. The camu-camu fruit were acquired at the stage of commercial maturity, Yurican on the farm, located at km 100 of the AM-010 highway, in the city of Rio Preto da Eva (Amazonas). Are pulped for formulating the nectar and then stored in sterile bottles properly. Participants were 17 adults normocholesterolemic. After selecting the sample, subjects were divided into two groups: the intervention group (IG) received the camu-camu and the second group, the control group (CG) received vitamica C synthetic, both at a concentration of 500 mg of ascorbic for 15 days. Biochemical tests were performed at the beginning and end of the intervention in order to check for possible interferences in total cholesterol and fractions, triglycerides and glucose. After fifteen days of consumption of the camu-camu, GI presented a reduction of 4.0% in average total cholesterol. In the control group the mean initial cholesterol was found to be 145 mg / dL and end of 148 mg / dL but no significant difference between the study groups. Regarding the concentrations of HDL-cholesterol, there was no significant difference between treatments (p> 0.05), regardless of the type of intervention, but the CG showed a trend of 11% increase in HDL-cholesterol. As for the plasma concentration of LDL-cholesterol was observed in GI a reduction of 2.4% in GC and there was an increase of 10.8%, but these values do not differ statistically. The present study showed a tendency to decrease triglyceride levels in both groups, a decrease of 10.2% for GI and 25.8% for GC. The glucose concentration decreased by 2.4% for GI and an increase of 10.8% for the GC, but with no significant difference between groups (p> 0.05). It is concluded that ingestion of the camu-camu result showed more efficient when compared to synthetic vitamin C. The 500 mg dose of vitamin C may be established as reference for future studies in patients with hypercholesterolemia or have an inadequate intake of the vitamin.
publishDate 2012
dc.date.issued.fl_str_mv 2012-08-27
dc.date.accessioned.fl_str_mv 2016-08-29T13:02:11Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
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dc.identifier.citation.fl_str_mv GONÇALVES, Flávia Amaro. Efeito do néctar de camu-camu (Myrciaria dubia (Kunth) McVaugh) nos níveis séricos de colesterol, triglicerídeos e glicose em adultos. 2012. 73 f. Dissertação (Mestrado em Ciência de Alimentos) - Universidade Federal do Amazonas, Manaus, 2012.
dc.identifier.uri.fl_str_mv http://tede.ufam.edu.br/handle/tede/5169
identifier_str_mv GONÇALVES, Flávia Amaro. Efeito do néctar de camu-camu (Myrciaria dubia (Kunth) McVaugh) nos níveis séricos de colesterol, triglicerídeos e glicose em adultos. 2012. 73 f. Dissertação (Mestrado em Ciência de Alimentos) - Universidade Federal do Amazonas, Manaus, 2012.
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