Bioprodutos derivados de biomassa vegetal no combate ao mosquito transmissor da dengue - Aedes aegypti

Detalhes bibliográficos
Ano de defesa: 2016
Autor(a) principal: Esmeraldo, Milena Alencar
Orientador(a): Mazzetto, Selma Elaine
Banca de defesa: Não Informado pela instituição
Tipo de documento: Tese
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Não Informado pela instituição
Programa de Pós-Graduação: Não Informado pela instituição
Departamento: Não Informado pela instituição
País: Não Informado pela instituição
Palavras-chave em Português:
Link de acesso: http://www.repositorio.ufc.br/handle/riufc/21454
Resumo: The Aedes aegypti mosquito is the main vector responsible for the spread of diseases like Chikungunya Fever, Zika and Dengue. Due to the absence of an effective vaccine for all kinds of diseases, the control is still accomplished through the elimination of potential mosquito breeding grounds by applying larvicides during the period of transmission. Regarding to pesticides, the most used are becoming obsolete due to the emergence of resistant strains of mosquitoes. Given this context, this study aimed at obtaining, characterizing and testing bioproducts to selective control of larvae and eggs of Aedes aegypti, adding value to the plant biomass, more precisely the Cashew Nut Shell Liquid technical and natural and constituents cardanol, cardol acting as core material and galactomannans derived of the endosperm of seeds of Adenanthera pavonina L. species as encapsulant. Encapsulated bioproducts, obtained by spray drying Spray Dryer, were characterized by spectroscopy Scanning Electron Microscopy - SEM, Thermogravimetric analysis - TG, Dynamic Light Scattering - DLS and through the kinetic profiles of release in vivo and in vitro. Laboratory bioassays were performed with larvae of the 3rd stage Aedes aegypti mosquito at different concentrations (10 - 20 - 40 – 80 -100 – 200 - 400 - 800 - 1000) ppm of bioproducts. Above 200 ppm concentration all bioproducts showed mortality rates above 80%, mainly noted for LCC natural, and the percentage considered acceptable by the World Health Organization - WHO to larvicides. Biological assays oviposition and ovicidal activity in the concentration range (200 - 500 - 800) ppm were also performed showing percentage repellence oviposition above 60% and low rates of hatching eggs and larvae growth. These results bring good prospects regarding the use of bioproducts in combat / control the mosquito Aedes aegypti suggesting potential applications in the precepts of Green Chemistry.
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spelling Esmeraldo, Milena AlencarMazzetto, Selma Elaine2016-12-29T19:21:09Z2016-12-29T19:21:09Z2016ESMERALDO, Milena Alencar. Bioprodutos derivados de biomassa vegetal no combate ao mosquito transmissor da dengue - Aedes aegypti. 2016. 117 f. Tese (Doutorado em Biotecnologia)-Universidade Federal do Ceará, Fortaleza, 2016.http://www.repositorio.ufc.br/handle/riufc/21454The Aedes aegypti mosquito is the main vector responsible for the spread of diseases like Chikungunya Fever, Zika and Dengue. Due to the absence of an effective vaccine for all kinds of diseases, the control is still accomplished through the elimination of potential mosquito breeding grounds by applying larvicides during the period of transmission. Regarding to pesticides, the most used are becoming obsolete due to the emergence of resistant strains of mosquitoes. Given this context, this study aimed at obtaining, characterizing and testing bioproducts to selective control of larvae and eggs of Aedes aegypti, adding value to the plant biomass, more precisely the Cashew Nut Shell Liquid technical and natural and constituents cardanol, cardol acting as core material and galactomannans derived of the endosperm of seeds of Adenanthera pavonina L. species as encapsulant. Encapsulated bioproducts, obtained by spray drying Spray Dryer, were characterized by spectroscopy Scanning Electron Microscopy - SEM, Thermogravimetric analysis - TG, Dynamic Light Scattering - DLS and through the kinetic profiles of release in vivo and in vitro. Laboratory bioassays were performed with larvae of the 3rd stage Aedes aegypti mosquito at different concentrations (10 - 20 - 40 – 80 -100 – 200 - 400 - 800 - 1000) ppm of bioproducts. Above 200 ppm concentration all bioproducts showed mortality rates above 80%, mainly noted for LCC natural, and the percentage considered acceptable by the World Health Organization - WHO to larvicides. Biological assays oviposition and ovicidal activity in the concentration range (200 - 500 - 800) ppm were also performed showing percentage repellence oviposition above 60% and low rates of hatching eggs and larvae growth. These results bring good prospects regarding the use of bioproducts in combat / control the mosquito Aedes aegypti suggesting potential applications in the precepts of Green Chemistry.O mosquito Aedes aegypti é o principal transmissor responsável pela disseminação de doenças como Febre Chikungunya, Zika e Dengue. Na ausência de uma vacina eficaz para todos os tipos de afecções transmitidas, o controle ainda é realizado por meio da eliminação dos criadouros potenciais dos mosquitos através da aplicação de larvicidas e inseticidas durante o período de transmissão. No tocante aos inseticidas, os mais usados estão se tornando obsoletos devido ao surgimento de linhagens de mosquitos resistentes. Dentro deste contexto, este trabalho tem como proposta a obtenção, caracterização e aplicação de bioprodutos para o controle das larvas e ovos do mosquito Aedes aegypti, a partir principalmente de biomassa vegetal, mais precisamente o Líquido da casca da castanha de caju natural e técnico, os constituintes cardanol, cardol, atuando como material de núcleo e galactomananas oriundas de endospermas de sementes da espécie Adenanthera pavonina L. como material encapsulante. Os bioprodutos encapsulados, obtidos através de secagem por atomização em Spray Dryer, foram caracterizados estruturalmente por espectroscopia de Microscopia Eletrônica de Varredura - MEV, Termogravimetria - TG, Espalhamento de Luz Dinâmico - DLS e através dos perfis cinéticos de liberação in vivo e in vitro. Ensaios biológicos com larvas de 3º estágio do mosquito Aedes aegypti foram realizados em diferentes concentrações (10 – 20 – 40 – 80 – 100 - 200 – 400 -800 – 1000) ppm dos bioprodutos. Em concentrações acima de 200 ppm todos os bioprodutos apresentaram índices de mortalidade acima de 80%, principalmente observado para o LCC natural, sendo este percentual considerado satisfatório para larvicidas pela Organização Mundial de Sáude - OMS. Ensaios biológicos de atividade de oviposição e ovicida no intervalo de concentrações (200 - 500 – 800) ppm também foram realizados apresentando percentuais de repelência à oviposição acima de 60 % bem como baixos índices de eclosão dos ovos e crescimento das larvas. Esses resultados trazem boas perspectivas quanto à utilização destes bioprodutos no combate/controle ao mosquito Aedes aegypti sugerindo potenciais aplicações nos preceitos da Química Verde.GalactomananaAedes aegyptiAtividade larvicida e ovicida, LCC.Química dos produtos naturaisBioprodutos derivados de biomassa vegetal no combate ao mosquito transmissor da dengue - Aedes aegyptiBioproducts from biomass plant from Adenanthera pavonina and Cashew Nut Shell Liquid – CNSL with potential larvicidal and ovicidal activity against the mosquito Aedes aegyptiinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/doctoralThesisporreponame:Repositório Institucional da Universidade Federal do Ceará (UFC)instname:Universidade Federal do Ceará (UFC)instacron:UFCinfo:eu-repo/semantics/openAccessORIGINAL2016_tese_maesmeraldo.pdf2016_tese_maesmeraldo.pdfapplication/pdf4084351http://repositorio.ufc.br/bitstream/riufc/21454/1/2016_tese_maesmeraldo.pdf3f99b44d3b25e9eb88071633bc173e56MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748http://repositorio.ufc.br/bitstream/riufc/21454/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52riufc/214542022-09-21 16:29:33.569oai:repositorio.ufc.br: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Repositório InstitucionalPUBhttp://www.repositorio.ufc.br/ri-oai/requestbu@ufc.br || repositorio@ufc.bropendoar:2022-09-21T19:29:33Repositório Institucional da Universidade Federal do Ceará (UFC) - Universidade Federal do Ceará (UFC)false
dc.title.pt_BR.fl_str_mv Bioprodutos derivados de biomassa vegetal no combate ao mosquito transmissor da dengue - Aedes aegypti
dc.title.en.pt_BR.fl_str_mv Bioproducts from biomass plant from Adenanthera pavonina and Cashew Nut Shell Liquid – CNSL with potential larvicidal and ovicidal activity against the mosquito Aedes aegypti
title Bioprodutos derivados de biomassa vegetal no combate ao mosquito transmissor da dengue - Aedes aegypti
spellingShingle Bioprodutos derivados de biomassa vegetal no combate ao mosquito transmissor da dengue - Aedes aegypti
Esmeraldo, Milena Alencar
Galactomanana
Aedes aegypti
Atividade larvicida e ovicida, LCC.
Química dos produtos naturais
title_short Bioprodutos derivados de biomassa vegetal no combate ao mosquito transmissor da dengue - Aedes aegypti
title_full Bioprodutos derivados de biomassa vegetal no combate ao mosquito transmissor da dengue - Aedes aegypti
title_fullStr Bioprodutos derivados de biomassa vegetal no combate ao mosquito transmissor da dengue - Aedes aegypti
title_full_unstemmed Bioprodutos derivados de biomassa vegetal no combate ao mosquito transmissor da dengue - Aedes aegypti
title_sort Bioprodutos derivados de biomassa vegetal no combate ao mosquito transmissor da dengue - Aedes aegypti
author Esmeraldo, Milena Alencar
author_facet Esmeraldo, Milena Alencar
author_role author
dc.contributor.author.fl_str_mv Esmeraldo, Milena Alencar
dc.contributor.advisor1.fl_str_mv Mazzetto, Selma Elaine
contributor_str_mv Mazzetto, Selma Elaine
dc.subject.por.fl_str_mv Galactomanana
Aedes aegypti
Atividade larvicida e ovicida, LCC.
Química dos produtos naturais
topic Galactomanana
Aedes aegypti
Atividade larvicida e ovicida, LCC.
Química dos produtos naturais
description The Aedes aegypti mosquito is the main vector responsible for the spread of diseases like Chikungunya Fever, Zika and Dengue. Due to the absence of an effective vaccine for all kinds of diseases, the control is still accomplished through the elimination of potential mosquito breeding grounds by applying larvicides during the period of transmission. Regarding to pesticides, the most used are becoming obsolete due to the emergence of resistant strains of mosquitoes. Given this context, this study aimed at obtaining, characterizing and testing bioproducts to selective control of larvae and eggs of Aedes aegypti, adding value to the plant biomass, more precisely the Cashew Nut Shell Liquid technical and natural and constituents cardanol, cardol acting as core material and galactomannans derived of the endosperm of seeds of Adenanthera pavonina L. species as encapsulant. Encapsulated bioproducts, obtained by spray drying Spray Dryer, were characterized by spectroscopy Scanning Electron Microscopy - SEM, Thermogravimetric analysis - TG, Dynamic Light Scattering - DLS and through the kinetic profiles of release in vivo and in vitro. Laboratory bioassays were performed with larvae of the 3rd stage Aedes aegypti mosquito at different concentrations (10 - 20 - 40 – 80 -100 – 200 - 400 - 800 - 1000) ppm of bioproducts. Above 200 ppm concentration all bioproducts showed mortality rates above 80%, mainly noted for LCC natural, and the percentage considered acceptable by the World Health Organization - WHO to larvicides. Biological assays oviposition and ovicidal activity in the concentration range (200 - 500 - 800) ppm were also performed showing percentage repellence oviposition above 60% and low rates of hatching eggs and larvae growth. These results bring good prospects regarding the use of bioproducts in combat / control the mosquito Aedes aegypti suggesting potential applications in the precepts of Green Chemistry.
publishDate 2016
dc.date.accessioned.fl_str_mv 2016-12-29T19:21:09Z
dc.date.available.fl_str_mv 2016-12-29T19:21:09Z
dc.date.issued.fl_str_mv 2016
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/doctoralThesis
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dc.identifier.citation.fl_str_mv ESMERALDO, Milena Alencar. Bioprodutos derivados de biomassa vegetal no combate ao mosquito transmissor da dengue - Aedes aegypti. 2016. 117 f. Tese (Doutorado em Biotecnologia)-Universidade Federal do Ceará, Fortaleza, 2016.
dc.identifier.uri.fl_str_mv http://www.repositorio.ufc.br/handle/riufc/21454
identifier_str_mv ESMERALDO, Milena Alencar. Bioprodutos derivados de biomassa vegetal no combate ao mosquito transmissor da dengue - Aedes aegypti. 2016. 117 f. Tese (Doutorado em Biotecnologia)-Universidade Federal do Ceará, Fortaleza, 2016.
url http://www.repositorio.ufc.br/handle/riufc/21454
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