Validade da “escala de depressão geriátrica” em unidades primárias de saúde na cidade de Fortaleza, Ceará

Detalhes bibliográficos
Ano de defesa: 2004
Autor(a) principal: Castelo, Milena Sampaio
Orientador(a): Coelho Filho , João Macêdo
Banca de defesa: Não Informado pela instituição
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Não Informado pela instituição
Programa de Pós-Graduação: Não Informado pela instituição
Departamento: Não Informado pela instituição
País: Não Informado pela instituição
Palavras-chave em Português:
Link de acesso: http://www.repositorio.ufc.br/handle/riufc/1009
Resumo: Introduction – Depression is one of the major potentially treatable psychiatric disorders affecting geriatric patients. At primary care facilities up to 30-50% of depressed patients are misdiagnosed and therefore not treated adequately. Recognition of depression is best improved by routine screening using efficient and easily applicable instruments. One of the most widely used instruments, the Geriatric Depression Scale (GDS), has been sufficiently validated in samples from specialized or out-sourced services. However, few studies, none of them from Brazil, have evaluated the performance of the GDS at the level of primary care in which most geriatric patients with depression are treated, making it hard to generalize existing results to this context. Objectives – 1) to determine the sensitivity, specificity, positive predictive value, negative predictive value and likelihood ratio in relation to the GDS comparing findings to structured clinical interviews for disorders of Axis I of the DSM-IV (SCID-I); 2) to build a Receiver Operator Characteristic Curve (ROC) determining the ideal cut-off point for primary care patients; 3) to determine the prevalence of episodes of major depression in geriatric primary care patients; 4) to identify the socio-demographic profile of geriatric primary care patients; 5) to examine geriatric patients presenting with episodes of depression and/or dysthymic disorders while taking anti-depressants. Method – cross-sectional study involving 220 geriatric patients from four health facilities. A questionnaire providing a global profile of the study population was applied, as well as the GDS and structured clinical interviews for disorders in Axis I of the DSM-IV (SCID-I). The first two instruments were applied by a trained interviewer and the SCID (gold standard) was applied by a trained psychiatrist. Results – The prevalence of episodes of major depression and/or dysthymic disorders was 17.27%. The best cut-off point with GDS-30 was 10/11 (case/non-case) with a sensitivity of 92.1% (CI 77.5–97.9), specificity 79.7% (CI = 72.9–85.1), accuracy 81.8% and likelihood ratio 4.5. The best cut-off point with GDS-15 was 4/5 with a sensitivity of 86.8% (CI = 71.1–95.1), specificity 82.4% (CI = 75.9–87.5), accuracy 83.1% and likelihood ratio 4.9. The best cut-off point with GDS-4 was 0/1 with a sensitivity of 84.2% (CI = 68.1–93.4), specificity 74.7% (CI = 67.7–80.7), accuracy 76.30% and likelihood ratio 3.9. With GDS-1 the sensitivity was 52.6% (CI = 36.0–68.7%). Conclusions – GDS-30 is an excellent screening instrument for episodes of major depression and/or dysthymic disorders at primary care facilities due to its high sensitivity and high negative predictive value. Reduced versions with 15 and 4 items proved good screening tests requiring less time to be applied. The systematic use of GDS at primary care facilities is recommended in order to identify a greater number of cases of depression and thereby offer a more adequate treatment.
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spelling Castelo, Milena SampaioCoelho Filho , João Macêdo2011-11-01T13:27:03Z2011-11-01T13:27:03Z2004CASTELO, M. S. Validade da “escala de depressão geriátrica” em unidades primárias de saúde na cidade de Fortaleza, Ceará. 2004. 113 f. Dissertação (Mestrado em Medicina) - Faculdade de Medicina. Universidade Federal do Ceará, Fortaleza, 2004.http://www.repositorio.ufc.br/handle/riufc/1009Introduction – Depression is one of the major potentially treatable psychiatric disorders affecting geriatric patients. At primary care facilities up to 30-50% of depressed patients are misdiagnosed and therefore not treated adequately. Recognition of depression is best improved by routine screening using efficient and easily applicable instruments. One of the most widely used instruments, the Geriatric Depression Scale (GDS), has been sufficiently validated in samples from specialized or out-sourced services. However, few studies, none of them from Brazil, have evaluated the performance of the GDS at the level of primary care in which most geriatric patients with depression are treated, making it hard to generalize existing results to this context. Objectives – 1) to determine the sensitivity, specificity, positive predictive value, negative predictive value and likelihood ratio in relation to the GDS comparing findings to structured clinical interviews for disorders of Axis I of the DSM-IV (SCID-I); 2) to build a Receiver Operator Characteristic Curve (ROC) determining the ideal cut-off point for primary care patients; 3) to determine the prevalence of episodes of major depression in geriatric primary care patients; 4) to identify the socio-demographic profile of geriatric primary care patients; 5) to examine geriatric patients presenting with episodes of depression and/or dysthymic disorders while taking anti-depressants. Method – cross-sectional study involving 220 geriatric patients from four health facilities. A questionnaire providing a global profile of the study population was applied, as well as the GDS and structured clinical interviews for disorders in Axis I of the DSM-IV (SCID-I). The first two instruments were applied by a trained interviewer and the SCID (gold standard) was applied by a trained psychiatrist. Results – The prevalence of episodes of major depression and/or dysthymic disorders was 17.27%. The best cut-off point with GDS-30 was 10/11 (case/non-case) with a sensitivity of 92.1% (CI 77.5–97.9), specificity 79.7% (CI = 72.9–85.1), accuracy 81.8% and likelihood ratio 4.5. The best cut-off point with GDS-15 was 4/5 with a sensitivity of 86.8% (CI = 71.1–95.1), specificity 82.4% (CI = 75.9–87.5), accuracy 83.1% and likelihood ratio 4.9. The best cut-off point with GDS-4 was 0/1 with a sensitivity of 84.2% (CI = 68.1–93.4), specificity 74.7% (CI = 67.7–80.7), accuracy 76.30% and likelihood ratio 3.9. With GDS-1 the sensitivity was 52.6% (CI = 36.0–68.7%). Conclusions – GDS-30 is an excellent screening instrument for episodes of major depression and/or dysthymic disorders at primary care facilities due to its high sensitivity and high negative predictive value. Reduced versions with 15 and 4 items proved good screening tests requiring less time to be applied. The systematic use of GDS at primary care facilities is recommended in order to identify a greater number of cases of depression and thereby offer a more adequate treatment.Introdução – Depressão é um dos transtornos psiquiátricos mais comuns em pessoas idosas, estando associada à maior morbimortalidade e aumento de custos. Apesar disto, 30 a 50% dos casos permanece não identificada e sem tratamento, o que tem motivado o desenvolvimento de instrumentos de rastreamento a serem utilizados na prática clínica. Um dos mais amplamente utilizados é a Escala de Depressão Geriátrica (Geriatric Depression Scale – GDS) que tem sido amplamente validada em amostras de serviços especializados e terciários. Poucos estudos em outros países, e nenhum no Brasil, no entanto, avaliaram o desempenho da GDS em nível primário de saúde, o que torna incerta a generalização dos resultados para esse contexto, onde a maioria das pessoas idosas com depressão é efetivamente atendida. Objetivos – determinar a validade da GDS, nas versões 30, 15, 4 e 1 itens, em nível primário de saúde, através de estimativa da sensibilidade, especificidade, valor preditivo positivo, valor preditivo negativo e razão de verossimilhança. Identificar os melhores pontos de corte dos escores da GDS, em suas diferentes versões, para rastreamento de depressão em nível primário de saúde. Método – Estudo transversal, com 220 pacientes idosos consecutivamente atendidos em quatro unidades primárias de saúde. Foram aplicados um questionário que forneceu uma visão global do perfil da população estudada; a Escala de Depressão Geriátrica (GDS) e a Entrevista Clínica Estruturada para Transtornos do Eixo I do DSM-IV (SCID-I), assumido como padrão-ouro. Os dois primeiros instrumentos foram aplicados por um entrevistador treinado e a SCID por médico psiquiatra. Resultados – A prevalência de Episódio Depressivo Maior e/ou transtorno distímico foi de 17,27%. O melhor ponto de corte da GDS 30 foi 10/11 (caso/não caso) que revelou sensibilidade = 92,1% (IC 95% = 77,5 - 97,9%), especificidade = 79,7% (IC 95% = 72,9 – 85,1%), acurácia = 81,8% e razão de verossimilhança = 4,5. O melhor ponto de corte da GDS 15 foi 4/5 com sensibilidade = 86,8% (IC 95% = 71,1 – 95,1%), especificidade = 82,4% (IC 95% = 75,9 –87,5%), acurácia = 83,1% e razão de verossimilhança = 4,9. O da GDS-4 foi 0/1 com sensibilidade = 84,2%(IC 95% = 68,1-93,4%), especificidade = 74,7% (IC 95% = 67,7 –80,7%), acurácia = 76,30% e Razão de verossimihança = 3,9. A GDS-1 teve uma sensibilidade de 52,6% (IC 95%=36,0 - 68,7%). Conclusões: A GDS-30 é um ótimo instrumento de rastreamento para episódio depressivo maior e/ou transtorno distímico, em unidades de atenção primária, dado sua alta sensibilidade e alto valor preditivo negativo. As versões reduzidas com 15 e 4 itens demonstraram ser bons testes de rastreamento, com a vantagem de requererem menos tempo para aplicação. O uso sistemático da GDS, em unidades de atenção primária de saúde, é recomendado para que haja uma maior identificação desses casos, permitindo tratamento adequado.Transtornos de AdaptaçãoAtenção Primária à SaúdeTranstorno DepressivoGeriatriaValidade da “escala de depressão geriátrica” em unidades primárias de saúde na cidade de Fortaleza, CearáValidity of the "scale of geriatrical depression" in primary units of health in the city of Fortaleza, Cearáinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisporreponame:Repositório Institucional da Universidade Federal do Ceará (UFC)instname:Universidade Federal do Ceará (UFC)instacron:UFCinfo:eu-repo/semantics/openAccessLICENSElicense.txtlicense.txttext/plain; charset=utf-81748http://repositorio.ufc.br/bitstream/riufc/1009/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52ORIGINAL2004_dis_mscastelo.pdf2004_dis_mscastelo.pdfapplication/pdf1147546http://repositorio.ufc.br/bitstream/riufc/1009/1/2004_dis_mscastelo.pdfe0a0f8def9ed27104cfcc36f390faffdMD51riufc/10092019-01-17 07:46:45.678oai:repositorio.ufc.br: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Repositório InstitucionalPUBhttp://www.repositorio.ufc.br/ri-oai/requestbu@ufc.br || repositorio@ufc.bropendoar:2019-01-17T10:46:45Repositório Institucional da Universidade Federal do Ceará (UFC) - Universidade Federal do Ceará (UFC)false
dc.title.pt_BR.fl_str_mv Validade da “escala de depressão geriátrica” em unidades primárias de saúde na cidade de Fortaleza, Ceará
dc.title.en.pt_BR.fl_str_mv Validity of the "scale of geriatrical depression" in primary units of health in the city of Fortaleza, Ceará
title Validade da “escala de depressão geriátrica” em unidades primárias de saúde na cidade de Fortaleza, Ceará
spellingShingle Validade da “escala de depressão geriátrica” em unidades primárias de saúde na cidade de Fortaleza, Ceará
Castelo, Milena Sampaio
Transtornos de Adaptação
Atenção Primária à Saúde
Transtorno Depressivo
Geriatria
title_short Validade da “escala de depressão geriátrica” em unidades primárias de saúde na cidade de Fortaleza, Ceará
title_full Validade da “escala de depressão geriátrica” em unidades primárias de saúde na cidade de Fortaleza, Ceará
title_fullStr Validade da “escala de depressão geriátrica” em unidades primárias de saúde na cidade de Fortaleza, Ceará
title_full_unstemmed Validade da “escala de depressão geriátrica” em unidades primárias de saúde na cidade de Fortaleza, Ceará
title_sort Validade da “escala de depressão geriátrica” em unidades primárias de saúde na cidade de Fortaleza, Ceará
author Castelo, Milena Sampaio
author_facet Castelo, Milena Sampaio
author_role author
dc.contributor.author.fl_str_mv Castelo, Milena Sampaio
dc.contributor.advisor1.fl_str_mv Coelho Filho , João Macêdo
contributor_str_mv Coelho Filho , João Macêdo
dc.subject.por.fl_str_mv Transtornos de Adaptação
Atenção Primária à Saúde
Transtorno Depressivo
Geriatria
topic Transtornos de Adaptação
Atenção Primária à Saúde
Transtorno Depressivo
Geriatria
description Introduction – Depression is one of the major potentially treatable psychiatric disorders affecting geriatric patients. At primary care facilities up to 30-50% of depressed patients are misdiagnosed and therefore not treated adequately. Recognition of depression is best improved by routine screening using efficient and easily applicable instruments. One of the most widely used instruments, the Geriatric Depression Scale (GDS), has been sufficiently validated in samples from specialized or out-sourced services. However, few studies, none of them from Brazil, have evaluated the performance of the GDS at the level of primary care in which most geriatric patients with depression are treated, making it hard to generalize existing results to this context. Objectives – 1) to determine the sensitivity, specificity, positive predictive value, negative predictive value and likelihood ratio in relation to the GDS comparing findings to structured clinical interviews for disorders of Axis I of the DSM-IV (SCID-I); 2) to build a Receiver Operator Characteristic Curve (ROC) determining the ideal cut-off point for primary care patients; 3) to determine the prevalence of episodes of major depression in geriatric primary care patients; 4) to identify the socio-demographic profile of geriatric primary care patients; 5) to examine geriatric patients presenting with episodes of depression and/or dysthymic disorders while taking anti-depressants. Method – cross-sectional study involving 220 geriatric patients from four health facilities. A questionnaire providing a global profile of the study population was applied, as well as the GDS and structured clinical interviews for disorders in Axis I of the DSM-IV (SCID-I). The first two instruments were applied by a trained interviewer and the SCID (gold standard) was applied by a trained psychiatrist. Results – The prevalence of episodes of major depression and/or dysthymic disorders was 17.27%. The best cut-off point with GDS-30 was 10/11 (case/non-case) with a sensitivity of 92.1% (CI 77.5–97.9), specificity 79.7% (CI = 72.9–85.1), accuracy 81.8% and likelihood ratio 4.5. The best cut-off point with GDS-15 was 4/5 with a sensitivity of 86.8% (CI = 71.1–95.1), specificity 82.4% (CI = 75.9–87.5), accuracy 83.1% and likelihood ratio 4.9. The best cut-off point with GDS-4 was 0/1 with a sensitivity of 84.2% (CI = 68.1–93.4), specificity 74.7% (CI = 67.7–80.7), accuracy 76.30% and likelihood ratio 3.9. With GDS-1 the sensitivity was 52.6% (CI = 36.0–68.7%). Conclusions – GDS-30 is an excellent screening instrument for episodes of major depression and/or dysthymic disorders at primary care facilities due to its high sensitivity and high negative predictive value. Reduced versions with 15 and 4 items proved good screening tests requiring less time to be applied. The systematic use of GDS at primary care facilities is recommended in order to identify a greater number of cases of depression and thereby offer a more adequate treatment.
publishDate 2004
dc.date.issued.fl_str_mv 2004
dc.date.accessioned.fl_str_mv 2011-11-01T13:27:03Z
dc.date.available.fl_str_mv 2011-11-01T13:27:03Z
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dc.identifier.citation.fl_str_mv CASTELO, M. S. Validade da “escala de depressão geriátrica” em unidades primárias de saúde na cidade de Fortaleza, Ceará. 2004. 113 f. Dissertação (Mestrado em Medicina) - Faculdade de Medicina. Universidade Federal do Ceará, Fortaleza, 2004.
dc.identifier.uri.fl_str_mv http://www.repositorio.ufc.br/handle/riufc/1009
identifier_str_mv CASTELO, M. S. Validade da “escala de depressão geriátrica” em unidades primárias de saúde na cidade de Fortaleza, Ceará. 2004. 113 f. Dissertação (Mestrado em Medicina) - Faculdade de Medicina. Universidade Federal do Ceará, Fortaleza, 2004.
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