Efeito do treinamento físico agudo pós prandial sobre a faixa de esvaziamento gástrico de uma refeição líquida em ratos acordados

• Ano de defesa: 2016
• Autor(a) principal: Leal, Israel Wesley Pinto
• Orientador(a): Graça, José Ronaldo Vasconcelos da
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Biblioteca da Universidade Federal do Ceará
• Palavras-chave em Português: Exercício físico; Esvaziamento gástrico; Acidose metabólica
• Link de acesso: http://www.repositorio.ufc.br/handle/riufc/62152

Physical exercise (PE) is responsible for promoting the physical, mental and social well-being. However, the high intensity contributes to gastrointestinal symptoms. Had as objective evaluating the effect of acute post-prandial physical exercise on the rate of gastric emptying (GE) of a liquid meal in awake rats. Wistar rats (280-350g) were used, provided by the central vivarium of the Federal University of Ceará and then adapted in collective tank with 5 cm of water for 10, 20, 30, 40 and 40 min respectively for 5 days . Then, they were fasted for 24 hours with free access to oral rehydration solution (ORS). On the day of the experiment they were divided into two groups: sedentary and trained. After, the animals were recorded with 1.5 mL of phenol red solution trained for 5, 10 and 15 min and sacrificed into 15, 20 and 30 min postprandial. The sedentary group was performed under the same conditions of the adaptation period and the trained group was placed in a cylindrical tube, with 50 cm of water, loaded with 5% of body weight. Then GE rates were measured by a spectrophotometer. It was carried out the pretreatment with sodium bicarbonate (500mg / kg) 40 min before the PE in some groups to compare the GE rate. About the biochemical variables, blood samples were collected immediately after the guillotine and sent for analysis. Hemodynamic parameters were achieved through the tail plethysmography using PowerLab to record. Data were analyzed by average ± SEM, "t" test of Student and ANOVA followed by Bonferroni's (* P <0.05). Acute PE promoted retardation on GE to animals trained for 15 min after 30 min postprandial (P <0.0001), not evidenced in the groups trained for 5 and 10 min. Gastric retention was reversed by pretreatment bicarbonate after 30 min postprandial (P <0.0001). In those trained for 15 min it was noted hyperlactatemia and decreased bicarbonate. Hemodynamic variables (SAP and HF) had a peak at the end of 15 min workout, returned to baseline parameters after 15 min of recovery after training. Acute PE promotes retardation of GE, with hyperlactatemia directly related to this case, being reversed by pretreatment with bicarbonate.