Identificação de dengue em pacientes com síndrome febril aguda

Detalhes bibliográficos
Ano de defesa: 2016
Autor(a) principal: Souza, Natália Vasconcelos de
Orientador(a): Lima, Danielle Malta
Banca de defesa: Não Informado pela instituição
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Não Informado pela instituição
Programa de Pós-Graduação: Não Informado pela instituição
Departamento: Não Informado pela instituição
País: Não Informado pela instituição
Palavras-chave em Português:
Link de acesso: http://www.repositorio.ufc.br/handle/riufc/60201
Resumo: Dengue is considered one arbovirus more important transmitted to humans. Of the Agreement with the World Health Organization (WHO) estimated that between 50-100 million people infected annually arise in over 100 Countries. Medium 550 thousand patients require hospitalization and 20,000 die from the disease. However, most cases are asymptomatic and can generate a not in seeking medical care and, as a consequence, an underestimation of the disease cases. The present study aimed to identify the main symptoms presented those participants with clinical suspicion of dengue, attended in primary care and tertiary institutions located in Fortaleza. Were evaluated 114 participants with clinical suspicion of dengue were recruited in and Clinic in the ward of São José Hospital for Infectious Diseases and NAS Units Primary Health Care (UAP) Mattos Dourado and Francisco Pereira de Almeida, in Fortaleza, in the period January 2013 to December 2014. The specific diagnosis of testicular done paragraph dengue Were: NS1 immunoassay, enzyme-linked immunosorbent ELISA IgG and IgM. Of the 114 participants, 78 (68.42%) Were Positive paragraph dengue in less than hum hair testicles Specific done, BEING 74 (64.9%) IgM Positive paragraph, 3 (2.6%) for NS1 and 1 (0, 8%) participants was positive in both techniques. The most affected age group was between 20-39 years old, being diagnosed with dengue participants in all month recruitment. There was considerable a incidence patients with possible secondary infection, suggesting a wide circulation make any Ceara State viruses, making it necessary an application effective actions paragraph once the transmitter agent and containment a greater awareness of the population. As samples used for IgM ELISA Test realization collected were do 1 at the 5th day of symptoms, not being the suggested by WHO to Test procedure, however getting a high positivity, these results show the need for more studies a fence application of this tool paragraph to get more early human diagnosis, allowing que this patient be conducted faster way, assisting in your so improvement and preventing que of this evolve for tables more graves.
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spelling Souza, Natália Vasconcelos deColares, Jeová Keny BaimaLima, Danielle Malta2021-09-01T13:15:18Z2021-09-01T13:15:18Z2016SOUZA, Natália Vasconcelos de. Identificação de dengue em pacientes com síndrome febril aguda. 2016. 74 f. Dissertação (Mestrado em Patologia) - Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, 2016.http://www.repositorio.ufc.br/handle/riufc/60201Dengue is considered one arbovirus more important transmitted to humans. Of the Agreement with the World Health Organization (WHO) estimated that between 50-100 million people infected annually arise in over 100 Countries. Medium 550 thousand patients require hospitalization and 20,000 die from the disease. However, most cases are asymptomatic and can generate a not in seeking medical care and, as a consequence, an underestimation of the disease cases. The present study aimed to identify the main symptoms presented those participants with clinical suspicion of dengue, attended in primary care and tertiary institutions located in Fortaleza. Were evaluated 114 participants with clinical suspicion of dengue were recruited in and Clinic in the ward of São José Hospital for Infectious Diseases and NAS Units Primary Health Care (UAP) Mattos Dourado and Francisco Pereira de Almeida, in Fortaleza, in the period January 2013 to December 2014. The specific diagnosis of testicular done paragraph dengue Were: NS1 immunoassay, enzyme-linked immunosorbent ELISA IgG and IgM. Of the 114 participants, 78 (68.42%) Were Positive paragraph dengue in less than hum hair testicles Specific done, BEING 74 (64.9%) IgM Positive paragraph, 3 (2.6%) for NS1 and 1 (0, 8%) participants was positive in both techniques. The most affected age group was between 20-39 years old, being diagnosed with dengue participants in all month recruitment. There was considerable a incidence patients with possible secondary infection, suggesting a wide circulation make any Ceara State viruses, making it necessary an application effective actions paragraph once the transmitter agent and containment a greater awareness of the population. As samples used for IgM ELISA Test realization collected were do 1 at the 5th day of symptoms, not being the suggested by WHO to Test procedure, however getting a high positivity, these results show the need for more studies a fence application of this tool paragraph to get more early human diagnosis, allowing que this patient be conducted faster way, assisting in your so improvement and preventing que of this evolve for tables more graves.A dengue é considerada a mais importante arbovirose transmitida aos seres humanos. De acordo com a Organização Mundial da Saúde (OMS), calcula-se que entre 50 a 100 milhões de pessoas infectadas surjam anualmente em mais de 100 países. Em média 550 mil doentes necessitam de hospitalização e 20 mil morrem devido à doença. Contudo, a maioria dos casos são assintomáticos, podendo gerar a não procura por atendimento médico e, como consequência, a subestimação dos casos da doença. O presente estudo teve por objetivo identificar os principais sintomas apresentados pelos participantes com suspeita clínica de dengue, atendidos em instituições de atenção primária e terciária localizadas no município de Fortaleza. Foram avaliados 114 participantes com suspeita clínica de dengue, recrutados no ambulatório e na enfermaria do Hospital São José de Doenças Infecciosas e nas Unidades de atenção primária à saúde (UAPS) Mattos Dourado e Francisco Pereira de Almeida, no município de Fortaleza, no período de janeiro de 2013 a dezembro de 2014. Os testes de diagnóstico específico realizados para dengue foram: imunocromatográfico NS1, imunoenzimático ELISA IgM e IgG. Dos 114 participantes, 78 (68,42%) foram positivos para dengue em pelo menos um dos testes específicos realizados, sendo 74 (64,9%) positivos para IgM , 3 (2,6%) para o NS1 e 1 (0,8%) participante foi positivo em ambos os testes. A faixa etária mais acometida foi entre 20 – 39 anos, sendo diagnosticados participantes com dengue em todos os meses de recrutamento. Observou-se uma considerável incidência de pacientes com possível infecção secundária, sugerindo uma ampla circulação do vírus no Estado do Ceará, tornando-se necessária a aplicação de ações mais efetivas para a contenção do agente transmissor e uma maior conscientização da população. As amostras utilizadas para realização do teste ELISA IgM foram coletadas do 1º ao 5º dia de sintomas, não sendo este o sugerido pela OMS para realização do teste, porém obtendo uma alta positividade, estes resultados demonstram a necessidade de mais estudos a cerca da aplicação desta ferramenta para se obter um diagnóstico mais precoce , permitindo que este paciente seja conduzido de forma mais rápida, auxiliando assim na sua melhora e impedindo que evolua para quadros mais graves.DengueAedesEnsaio de Imunoadsorção EnzimáticaIdentificação de dengue em pacientes com síndrome febril agudainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisporreponame:Repositório Institucional da Universidade Federal do Ceará (UFC)instname:Universidade Federal do Ceará (UFC)instacron:UFCinfo:eu-repo/semantics/openAccessLICENSElicense.txtlicense.txttext/plain; charset=utf-81748http://repositorio.ufc.br/bitstream/riufc/60201/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52ORIGINAL2016_dis_nvsouza.pdf2016_dis_nvsouza.pdfapplication/pdf1584928http://repositorio.ufc.br/bitstream/riufc/60201/1/2016_dis_nvsouza.pdf0cc011787df440e25a67b0b5101fe5d8MD51riufc/602012021-10-19 09:48:21.908oai:repositorio.ufc.br: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Repositório InstitucionalPUBhttp://www.repositorio.ufc.br/ri-oai/requestbu@ufc.br || repositorio@ufc.bropendoar:2021-10-19T12:48:21Repositório Institucional da Universidade Federal do Ceará (UFC) - Universidade Federal do Ceará (UFC)false
dc.title.pt_BR.fl_str_mv Identificação de dengue em pacientes com síndrome febril aguda
title Identificação de dengue em pacientes com síndrome febril aguda
spellingShingle Identificação de dengue em pacientes com síndrome febril aguda
Souza, Natália Vasconcelos de
Dengue
Aedes
Ensaio de Imunoadsorção Enzimática
title_short Identificação de dengue em pacientes com síndrome febril aguda
title_full Identificação de dengue em pacientes com síndrome febril aguda
title_fullStr Identificação de dengue em pacientes com síndrome febril aguda
title_full_unstemmed Identificação de dengue em pacientes com síndrome febril aguda
title_sort Identificação de dengue em pacientes com síndrome febril aguda
author Souza, Natália Vasconcelos de
author_facet Souza, Natália Vasconcelos de
author_role author
dc.contributor.co-advisor.none.fl_str_mv Colares, Jeová Keny Baima
dc.contributor.author.fl_str_mv Souza, Natália Vasconcelos de
dc.contributor.advisor1.fl_str_mv Lima, Danielle Malta
contributor_str_mv Lima, Danielle Malta
dc.subject.por.fl_str_mv Dengue
Aedes
Ensaio de Imunoadsorção Enzimática
topic Dengue
Aedes
Ensaio de Imunoadsorção Enzimática
description Dengue is considered one arbovirus more important transmitted to humans. Of the Agreement with the World Health Organization (WHO) estimated that between 50-100 million people infected annually arise in over 100 Countries. Medium 550 thousand patients require hospitalization and 20,000 die from the disease. However, most cases are asymptomatic and can generate a not in seeking medical care and, as a consequence, an underestimation of the disease cases. The present study aimed to identify the main symptoms presented those participants with clinical suspicion of dengue, attended in primary care and tertiary institutions located in Fortaleza. Were evaluated 114 participants with clinical suspicion of dengue were recruited in and Clinic in the ward of São José Hospital for Infectious Diseases and NAS Units Primary Health Care (UAP) Mattos Dourado and Francisco Pereira de Almeida, in Fortaleza, in the period January 2013 to December 2014. The specific diagnosis of testicular done paragraph dengue Were: NS1 immunoassay, enzyme-linked immunosorbent ELISA IgG and IgM. Of the 114 participants, 78 (68.42%) Were Positive paragraph dengue in less than hum hair testicles Specific done, BEING 74 (64.9%) IgM Positive paragraph, 3 (2.6%) for NS1 and 1 (0, 8%) participants was positive in both techniques. The most affected age group was between 20-39 years old, being diagnosed with dengue participants in all month recruitment. There was considerable a incidence patients with possible secondary infection, suggesting a wide circulation make any Ceara State viruses, making it necessary an application effective actions paragraph once the transmitter agent and containment a greater awareness of the population. As samples used for IgM ELISA Test realization collected were do 1 at the 5th day of symptoms, not being the suggested by WHO to Test procedure, however getting a high positivity, these results show the need for more studies a fence application of this tool paragraph to get more early human diagnosis, allowing que this patient be conducted faster way, assisting in your so improvement and preventing que of this evolve for tables more graves.
publishDate 2016
dc.date.issued.fl_str_mv 2016
dc.date.accessioned.fl_str_mv 2021-09-01T13:15:18Z
dc.date.available.fl_str_mv 2021-09-01T13:15:18Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.citation.fl_str_mv SOUZA, Natália Vasconcelos de. Identificação de dengue em pacientes com síndrome febril aguda. 2016. 74 f. Dissertação (Mestrado em Patologia) - Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, 2016.
dc.identifier.uri.fl_str_mv http://www.repositorio.ufc.br/handle/riufc/60201
identifier_str_mv SOUZA, Natália Vasconcelos de. Identificação de dengue em pacientes com síndrome febril aguda. 2016. 74 f. Dissertação (Mestrado em Patologia) - Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, 2016.
url http://www.repositorio.ufc.br/handle/riufc/60201
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