Concentração Alveolar Mínima do Isofluorano em catetos (Tayassu tajacu, LINNAEUS, 1758)

Detalhes bibliográficos
Ano de defesa: 2013
Autor(a) principal: Oliveira, Maria Gláucia Carlos de lattes
Orientador(a): Paula, Valéria Veras de lattes
Banca de defesa: Otsuki, Denise Aya lattes, Oliveira, Moacir Franco de lattes
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Federal Rural do Semi-Árido
Programa de Pós-Graduação: Programa de Pós-Graduação em Ciência Animal
Departamento: Centro de Ciências Agrárias - CCA
País: BR
Palavras-chave em Português:
Palavras-chave em Inglês:
Área do conhecimento CNPq:
Link de acesso: https://repositorio.ufersa.edu.br/handle/tede/385
Resumo: Inhalation anesthesia has been widespread in veterinary medicine. Nevertheless, its use in wild animals is still limited, having no studies on its use been observed in the species. The objective of the research was to determine the isoflurane minimum alveolar concentration (MAC) in peccaries and present the effects of its administration on the hemodynamic and respiratory variables, as well as data concerning the anesthesia recovery. The study used 10 male animals with age ranging from 1 to 3 years, from the Centro de Multiplicação de Animais Silvestres of Universidade Federal Rural do SemiÁrido, Brazil. All the animals had anesthesia induced with propofol 7mg.kg-1, were intubated and connected to the anesthetic circuit with isoflurane and 100% oxygen. The supramaximal noxious stimulation used was the interdigital pinch, which was performed after 15 minutes of waiting for each provided isoflurane concentration. When negative response to the stimulus was observed, the concentration was reduced by 20%; when positive response was verified, the stimulus was stopped, being the CAM value calculated from that point. Quantitative and qualitative data regarding recovery were also observed. Shapiro-Wilk test for normality was performed, as well as Levene test for equality of variance; the variables were subjected to One Way RM ANOVA for repeated measures followed by Tukey test, and the data expressed as mean and standard deviation. The MAC of isoflurane was 2.4% and the surgical MAC equal to 3.5%. Depressive action of isoflurane on blood pressure, heart and breathing rates was observed when compared to the average of the variables on awake animals; however, during maintenance of anesthesia, they remained stable. Metabolic acidosis was observed in the preanesthetic, which was offset after inhalation anesthesia. Recovery was quiet and smooth. It was concluded that the isoflurane MAC for peccaries was greater than that observed in related species. Isoflurane can be used in this species, being considered safe and effective. The animal s recovery after anesthesia with isoflurane was free from excitement
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spelling Paula, Valéria Veras dehttp://lattes.cnpq.br/9083821440600669Otsuki, Denise Ayahttp://lattes.cnpq.br/7478356557513705Oliveira, Moacir Franco dehttp://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4703980T5http://lattes.cnpq.br/4720039078909521Oliveira, Maria Gláucia Carlos de2016-08-15T20:31:30Z2016-06-092013-08-08OLIVEIRA, Maria Gláucia Carlos de. Maria Gláucia Carlos. Isoflurane minimum alveolar concentration in collared peccary (Tayassu tajacu). 2013. 84 f. Dissertação (Mestrado em Sanidade e Produção Animal) - Universidade Federal Rural do Semi-Árido, Mossoró, 2013.https://repositorio.ufersa.edu.br/handle/tede/385Inhalation anesthesia has been widespread in veterinary medicine. Nevertheless, its use in wild animals is still limited, having no studies on its use been observed in the species. The objective of the research was to determine the isoflurane minimum alveolar concentration (MAC) in peccaries and present the effects of its administration on the hemodynamic and respiratory variables, as well as data concerning the anesthesia recovery. The study used 10 male animals with age ranging from 1 to 3 years, from the Centro de Multiplicação de Animais Silvestres of Universidade Federal Rural do SemiÁrido, Brazil. All the animals had anesthesia induced with propofol 7mg.kg-1, were intubated and connected to the anesthetic circuit with isoflurane and 100% oxygen. The supramaximal noxious stimulation used was the interdigital pinch, which was performed after 15 minutes of waiting for each provided isoflurane concentration. When negative response to the stimulus was observed, the concentration was reduced by 20%; when positive response was verified, the stimulus was stopped, being the CAM value calculated from that point. Quantitative and qualitative data regarding recovery were also observed. Shapiro-Wilk test for normality was performed, as well as Levene test for equality of variance; the variables were subjected to One Way RM ANOVA for repeated measures followed by Tukey test, and the data expressed as mean and standard deviation. The MAC of isoflurane was 2.4% and the surgical MAC equal to 3.5%. Depressive action of isoflurane on blood pressure, heart and breathing rates was observed when compared to the average of the variables on awake animals; however, during maintenance of anesthesia, they remained stable. Metabolic acidosis was observed in the preanesthetic, which was offset after inhalation anesthesia. Recovery was quiet and smooth. It was concluded that the isoflurane MAC for peccaries was greater than that observed in related species. Isoflurane can be used in this species, being considered safe and effective. The animal s recovery after anesthesia with isoflurane was free from excitementA anestesia inalatória vem sendo amplamente difundida na medicina veterinária, no entanto seu uso em animais selvagens ainda é restrito, não sendo observado nenhum estudo referente à sua utilização na espécie Tayassu tajacu. O objetivo da pesquisa foi determinar a concentração alveolar mínima (CAM) do isofluorano em catetos e apresentar os efeitos desta administração sobre as variáveis hemodinâmicas e respiratórias, como também a qualidade da recuperação. Utilizou-se 10 animais, machos, com idade variando de 1 a 3 anos oriundos do Centro de Multiplicação de Animais Silvestres da Universidade Federal Rural do Semi-Árido, Brasil. Todos tiveram anestesia induzida com 7 mg.kg-1 de propofol e posteriormente foram conectados a circuito anestésico com isofluorano e oxigênio 100%. O estímulo noceptivo supramáximo adotado foi pinçamento interdigital, o qual era realizado após 15 minutos de espera para cada concentração de isofluorano fornecida. Ao ser observada resposta negativa frente ao estímulo a concentração era reduzida em 20%, quando verificada resposta positiva o estímulo era cessado, calculando-se a partir daí o valor da CAM. Observou-se dados quantitativos e qualitativos referentes à recuperação. Utilizou-se o teste de normalidade de Shapiro Wilk e de homogeneidade de variânica de Levene, as variáveis avaliadas foram submetidas à One Way ANOVA-RM para medidas repetidas, seguidas por Teste Tukey, sendo os dados expressos em média e desvio padrão. A CAM do isofluorano foi de 2,4%, sendo a CAM cirúrgica igual a 3,5%. Observou-se ação depressiva do isofluorano sobre a pressão arterial, frequência cardíaca e respiratória quando comparada a média dessas variáveis para animais acordados, entretanto durante a manutenção anestésica mantiveram-se estáveis. Observou-se acidose metabólica no período pré-anestésico o qual foi compensado após a realização da anestesia inalatória. A recuperação anestésica foi tranquila e rápida. Concluiu-se que a CAM do isofluorano para catetos foi maior que a observada em espécies afins. O isofluorano pode ser utilizado nesta espécie, sendo considerado seguro e eficaz. A recuperação dos animais após anestesia com isofluorano foi livre de excitaçãoCoordenação de Aperfeiçoamento de Pessoal de Nível Superiorapplication/pdfhttp://repositorio.ufersa.edu.br/retrieve/764/MariaGCO_DISSERT.pdf.jpgporUniversidade Federal Rural do Semi-ÁridoPrograma de Pós-Graduação em Ciência AnimalUFERSABRCentro de Ciências Agrárias - CCACC-BY-SAinfo:eu-repo/semantics/openAccessAnesthesiaWild animalSupramaximal stimulationRecoveryAnestesiaAnimal selvagemEstímulo supramáximoRecuperaçãoCNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIAConcentração Alveolar Mínima do Isofluorano em catetos (Tayassu tajacu, LINNAEUS, 1758)Maria Gláucia Carlos. Isoflurane minimum alveolar concentration in collared peccary (Tayassu tajacu)info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisreponame:Biblioteca Digital de Teses e Dissertações da UFERSAinstname:Universidade Federal Rural do Semi-Árido (UFERSA)instacron:UFERSATEXTMariaGCO_DISSERT.pdf.txtMariaGCO_DISSERT.pdf.txtExtracted texttext/plain145165https://repositorio.ufersa.edu.br//bitstream/tede/385/3/MariaGCO_DISSERT.pdf.txtbe347780ac01e61074b0858eadc200deMD53ORIGINALMariaGCO_DISSERT.pdfapplication/pdf3651986https://repositorio.ufersa.edu.br//bitstream/tede/385/1/MariaGCO_DISSERT.pdf2ab08d5fd194352621c2b0fa211f2e22MD51THUMBNAILMariaGCO_DISSERT.pdf.jpgMariaGCO_DISSERT.pdf.jpgGenerated Thumbnailimage/jpeg4028https://repositorio.ufersa.edu.br//bitstream/tede/385/2/MariaGCO_DISSERT.pdf.jpgddd7864de615b5634adf357598f82a50MD52tede/3852022-07-05 15:56:12.914oai:repositorio.ufersa.edu.br:tede/385Biblioteca Digital de Teses e Dissertaçõeshttps://repositorio.ufersa.edu.br/PUBhttp://bdtd.ufersa.edu.br/oai/requestdirecaosisbi@ufersa.edu.br|| direcaosisbi@ufersa.edu.bropendoar:2022-07-05T18:56:12Biblioteca Digital de Teses e Dissertações da UFERSA - Universidade Federal Rural do Semi-Árido (UFERSA)false
dc.title.por.fl_str_mv Concentração Alveolar Mínima do Isofluorano em catetos (Tayassu tajacu, LINNAEUS, 1758)
dc.title.alternative.eng.fl_str_mv Maria Gláucia Carlos. Isoflurane minimum alveolar concentration in collared peccary (Tayassu tajacu)
title Concentração Alveolar Mínima do Isofluorano em catetos (Tayassu tajacu, LINNAEUS, 1758)
spellingShingle Concentração Alveolar Mínima do Isofluorano em catetos (Tayassu tajacu, LINNAEUS, 1758)
Oliveira, Maria Gláucia Carlos de
Anesthesia
Wild animal
Supramaximal stimulation
Recovery
Anestesia
Animal selvagem
Estímulo supramáximo
Recuperação
CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA
title_short Concentração Alveolar Mínima do Isofluorano em catetos (Tayassu tajacu, LINNAEUS, 1758)
title_full Concentração Alveolar Mínima do Isofluorano em catetos (Tayassu tajacu, LINNAEUS, 1758)
title_fullStr Concentração Alveolar Mínima do Isofluorano em catetos (Tayassu tajacu, LINNAEUS, 1758)
title_full_unstemmed Concentração Alveolar Mínima do Isofluorano em catetos (Tayassu tajacu, LINNAEUS, 1758)
title_sort Concentração Alveolar Mínima do Isofluorano em catetos (Tayassu tajacu, LINNAEUS, 1758)
author Oliveira, Maria Gláucia Carlos de
author_facet Oliveira, Maria Gláucia Carlos de
author_role author
dc.contributor.advisor1.fl_str_mv Paula, Valéria Veras de
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/9083821440600669
dc.contributor.referee1.fl_str_mv Otsuki, Denise Aya
dc.contributor.referee1Lattes.fl_str_mv http://lattes.cnpq.br/7478356557513705
dc.contributor.referee2.fl_str_mv Oliveira, Moacir Franco de
dc.contributor.referee2Lattes.fl_str_mv http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4703980T5
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/4720039078909521
dc.contributor.author.fl_str_mv Oliveira, Maria Gláucia Carlos de
contributor_str_mv Paula, Valéria Veras de
Otsuki, Denise Aya
Oliveira, Moacir Franco de
dc.subject.eng.fl_str_mv Anesthesia
Wild animal
Supramaximal stimulation
Recovery
topic Anesthesia
Wild animal
Supramaximal stimulation
Recovery
Anestesia
Animal selvagem
Estímulo supramáximo
Recuperação
CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA
dc.subject.por.fl_str_mv Anestesia
Animal selvagem
Estímulo supramáximo
Recuperação
dc.subject.cnpq.fl_str_mv CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA
description Inhalation anesthesia has been widespread in veterinary medicine. Nevertheless, its use in wild animals is still limited, having no studies on its use been observed in the species. The objective of the research was to determine the isoflurane minimum alveolar concentration (MAC) in peccaries and present the effects of its administration on the hemodynamic and respiratory variables, as well as data concerning the anesthesia recovery. The study used 10 male animals with age ranging from 1 to 3 years, from the Centro de Multiplicação de Animais Silvestres of Universidade Federal Rural do SemiÁrido, Brazil. All the animals had anesthesia induced with propofol 7mg.kg-1, were intubated and connected to the anesthetic circuit with isoflurane and 100% oxygen. The supramaximal noxious stimulation used was the interdigital pinch, which was performed after 15 minutes of waiting for each provided isoflurane concentration. When negative response to the stimulus was observed, the concentration was reduced by 20%; when positive response was verified, the stimulus was stopped, being the CAM value calculated from that point. Quantitative and qualitative data regarding recovery were also observed. Shapiro-Wilk test for normality was performed, as well as Levene test for equality of variance; the variables were subjected to One Way RM ANOVA for repeated measures followed by Tukey test, and the data expressed as mean and standard deviation. The MAC of isoflurane was 2.4% and the surgical MAC equal to 3.5%. Depressive action of isoflurane on blood pressure, heart and breathing rates was observed when compared to the average of the variables on awake animals; however, during maintenance of anesthesia, they remained stable. Metabolic acidosis was observed in the preanesthetic, which was offset after inhalation anesthesia. Recovery was quiet and smooth. It was concluded that the isoflurane MAC for peccaries was greater than that observed in related species. Isoflurane can be used in this species, being considered safe and effective. The animal s recovery after anesthesia with isoflurane was free from excitement
publishDate 2013
dc.date.issued.fl_str_mv 2013-08-08
dc.date.accessioned.fl_str_mv 2016-08-15T20:31:30Z
dc.date.available.fl_str_mv 2016-06-09
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
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dc.identifier.citation.fl_str_mv OLIVEIRA, Maria Gláucia Carlos de. Maria Gláucia Carlos. Isoflurane minimum alveolar concentration in collared peccary (Tayassu tajacu). 2013. 84 f. Dissertação (Mestrado em Sanidade e Produção Animal) - Universidade Federal Rural do Semi-Árido, Mossoró, 2013.
dc.identifier.uri.fl_str_mv https://repositorio.ufersa.edu.br/handle/tede/385
identifier_str_mv OLIVEIRA, Maria Gláucia Carlos de. Maria Gláucia Carlos. Isoflurane minimum alveolar concentration in collared peccary (Tayassu tajacu). 2013. 84 f. Dissertação (Mestrado em Sanidade e Produção Animal) - Universidade Federal Rural do Semi-Árido, Mossoró, 2013.
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