Concentração Alveolar Mínima do Isofluorano em catetos (Tayassu tajacu, LINNAEUS, 1758)
Ano de defesa: | 2013 |
---|---|
Autor(a) principal: | |
Orientador(a): | |
Banca de defesa: | , |
Tipo de documento: | Dissertação |
Tipo de acesso: | Acesso aberto |
Idioma: | por |
Instituição de defesa: |
Universidade Federal Rural do Semi-Árido
|
Programa de Pós-Graduação: |
Programa de Pós-Graduação em Ciência Animal
|
Departamento: |
Centro de Ciências Agrárias - CCA
|
País: |
BR
|
Palavras-chave em Português: | |
Palavras-chave em Inglês: | |
Área do conhecimento CNPq: | |
Link de acesso: | https://repositorio.ufersa.edu.br/handle/tede/385 |
Resumo: | Inhalation anesthesia has been widespread in veterinary medicine. Nevertheless, its use in wild animals is still limited, having no studies on its use been observed in the species. The objective of the research was to determine the isoflurane minimum alveolar concentration (MAC) in peccaries and present the effects of its administration on the hemodynamic and respiratory variables, as well as data concerning the anesthesia recovery. The study used 10 male animals with age ranging from 1 to 3 years, from the Centro de Multiplicação de Animais Silvestres of Universidade Federal Rural do SemiÁrido, Brazil. All the animals had anesthesia induced with propofol 7mg.kg-1, were intubated and connected to the anesthetic circuit with isoflurane and 100% oxygen. The supramaximal noxious stimulation used was the interdigital pinch, which was performed after 15 minutes of waiting for each provided isoflurane concentration. When negative response to the stimulus was observed, the concentration was reduced by 20%; when positive response was verified, the stimulus was stopped, being the CAM value calculated from that point. Quantitative and qualitative data regarding recovery were also observed. Shapiro-Wilk test for normality was performed, as well as Levene test for equality of variance; the variables were subjected to One Way RM ANOVA for repeated measures followed by Tukey test, and the data expressed as mean and standard deviation. The MAC of isoflurane was 2.4% and the surgical MAC equal to 3.5%. Depressive action of isoflurane on blood pressure, heart and breathing rates was observed when compared to the average of the variables on awake animals; however, during maintenance of anesthesia, they remained stable. Metabolic acidosis was observed in the preanesthetic, which was offset after inhalation anesthesia. Recovery was quiet and smooth. It was concluded that the isoflurane MAC for peccaries was greater than that observed in related species. Isoflurane can be used in this species, being considered safe and effective. The animal s recovery after anesthesia with isoflurane was free from excitement |
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Paula, Valéria Veras dehttp://lattes.cnpq.br/9083821440600669Otsuki, Denise Ayahttp://lattes.cnpq.br/7478356557513705Oliveira, Moacir Franco dehttp://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4703980T5http://lattes.cnpq.br/4720039078909521Oliveira, Maria Gláucia Carlos de2016-08-15T20:31:30Z2016-06-092013-08-08OLIVEIRA, Maria Gláucia Carlos de. Maria Gláucia Carlos. Isoflurane minimum alveolar concentration in collared peccary (Tayassu tajacu). 2013. 84 f. Dissertação (Mestrado em Sanidade e Produção Animal) - Universidade Federal Rural do Semi-Árido, Mossoró, 2013.https://repositorio.ufersa.edu.br/handle/tede/385Inhalation anesthesia has been widespread in veterinary medicine. Nevertheless, its use in wild animals is still limited, having no studies on its use been observed in the species. The objective of the research was to determine the isoflurane minimum alveolar concentration (MAC) in peccaries and present the effects of its administration on the hemodynamic and respiratory variables, as well as data concerning the anesthesia recovery. The study used 10 male animals with age ranging from 1 to 3 years, from the Centro de Multiplicação de Animais Silvestres of Universidade Federal Rural do SemiÁrido, Brazil. All the animals had anesthesia induced with propofol 7mg.kg-1, were intubated and connected to the anesthetic circuit with isoflurane and 100% oxygen. The supramaximal noxious stimulation used was the interdigital pinch, which was performed after 15 minutes of waiting for each provided isoflurane concentration. When negative response to the stimulus was observed, the concentration was reduced by 20%; when positive response was verified, the stimulus was stopped, being the CAM value calculated from that point. Quantitative and qualitative data regarding recovery were also observed. Shapiro-Wilk test for normality was performed, as well as Levene test for equality of variance; the variables were subjected to One Way RM ANOVA for repeated measures followed by Tukey test, and the data expressed as mean and standard deviation. The MAC of isoflurane was 2.4% and the surgical MAC equal to 3.5%. Depressive action of isoflurane on blood pressure, heart and breathing rates was observed when compared to the average of the variables on awake animals; however, during maintenance of anesthesia, they remained stable. Metabolic acidosis was observed in the preanesthetic, which was offset after inhalation anesthesia. Recovery was quiet and smooth. It was concluded that the isoflurane MAC for peccaries was greater than that observed in related species. Isoflurane can be used in this species, being considered safe and effective. The animal s recovery after anesthesia with isoflurane was free from excitementA anestesia inalatória vem sendo amplamente difundida na medicina veterinária, no entanto seu uso em animais selvagens ainda é restrito, não sendo observado nenhum estudo referente à sua utilização na espécie Tayassu tajacu. O objetivo da pesquisa foi determinar a concentração alveolar mínima (CAM) do isofluorano em catetos e apresentar os efeitos desta administração sobre as variáveis hemodinâmicas e respiratórias, como também a qualidade da recuperação. Utilizou-se 10 animais, machos, com idade variando de 1 a 3 anos oriundos do Centro de Multiplicação de Animais Silvestres da Universidade Federal Rural do Semi-Árido, Brasil. Todos tiveram anestesia induzida com 7 mg.kg-1 de propofol e posteriormente foram conectados a circuito anestésico com isofluorano e oxigênio 100%. O estímulo noceptivo supramáximo adotado foi pinçamento interdigital, o qual era realizado após 15 minutos de espera para cada concentração de isofluorano fornecida. Ao ser observada resposta negativa frente ao estímulo a concentração era reduzida em 20%, quando verificada resposta positiva o estímulo era cessado, calculando-se a partir daí o valor da CAM. Observou-se dados quantitativos e qualitativos referentes à recuperação. Utilizou-se o teste de normalidade de Shapiro Wilk e de homogeneidade de variânica de Levene, as variáveis avaliadas foram submetidas à One Way ANOVA-RM para medidas repetidas, seguidas por Teste Tukey, sendo os dados expressos em média e desvio padrão. A CAM do isofluorano foi de 2,4%, sendo a CAM cirúrgica igual a 3,5%. Observou-se ação depressiva do isofluorano sobre a pressão arterial, frequência cardíaca e respiratória quando comparada a média dessas variáveis para animais acordados, entretanto durante a manutenção anestésica mantiveram-se estáveis. Observou-se acidose metabólica no período pré-anestésico o qual foi compensado após a realização da anestesia inalatória. A recuperação anestésica foi tranquila e rápida. Concluiu-se que a CAM do isofluorano para catetos foi maior que a observada em espécies afins. O isofluorano pode ser utilizado nesta espécie, sendo considerado seguro e eficaz. A recuperação dos animais após anestesia com isofluorano foi livre de excitaçãoCoordenação de Aperfeiçoamento de Pessoal de Nível Superiorapplication/pdfhttp://repositorio.ufersa.edu.br/retrieve/764/MariaGCO_DISSERT.pdf.jpgporUniversidade Federal Rural do Semi-ÁridoPrograma de Pós-Graduação em Ciência AnimalUFERSABRCentro de Ciências Agrárias - CCACC-BY-SAinfo:eu-repo/semantics/openAccessAnesthesiaWild animalSupramaximal stimulationRecoveryAnestesiaAnimal selvagemEstímulo supramáximoRecuperaçãoCNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIAConcentração Alveolar Mínima do Isofluorano em catetos (Tayassu tajacu, LINNAEUS, 1758)Maria Gláucia Carlos. Isoflurane minimum alveolar concentration in collared peccary (Tayassu tajacu)info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisreponame:Biblioteca Digital de Teses e Dissertações da UFERSAinstname:Universidade Federal Rural do Semi-Árido (UFERSA)instacron:UFERSATEXTMariaGCO_DISSERT.pdf.txtMariaGCO_DISSERT.pdf.txtExtracted texttext/plain145165https://repositorio.ufersa.edu.br//bitstream/tede/385/3/MariaGCO_DISSERT.pdf.txtbe347780ac01e61074b0858eadc200deMD53ORIGINALMariaGCO_DISSERT.pdfapplication/pdf3651986https://repositorio.ufersa.edu.br//bitstream/tede/385/1/MariaGCO_DISSERT.pdf2ab08d5fd194352621c2b0fa211f2e22MD51THUMBNAILMariaGCO_DISSERT.pdf.jpgMariaGCO_DISSERT.pdf.jpgGenerated Thumbnailimage/jpeg4028https://repositorio.ufersa.edu.br//bitstream/tede/385/2/MariaGCO_DISSERT.pdf.jpgddd7864de615b5634adf357598f82a50MD52tede/3852022-07-05 15:56:12.914oai:repositorio.ufersa.edu.br:tede/385Biblioteca Digital de Teses e Dissertaçõeshttps://repositorio.ufersa.edu.br/PUBhttp://bdtd.ufersa.edu.br/oai/requestdirecaosisbi@ufersa.edu.br|| direcaosisbi@ufersa.edu.bropendoar:2022-07-05T18:56:12Biblioteca Digital de Teses e Dissertações da UFERSA - Universidade Federal Rural do Semi-Árido (UFERSA)false |
dc.title.por.fl_str_mv |
Concentração Alveolar Mínima do Isofluorano em catetos (Tayassu tajacu, LINNAEUS, 1758) |
dc.title.alternative.eng.fl_str_mv |
Maria Gláucia Carlos. Isoflurane minimum alveolar concentration in collared peccary (Tayassu tajacu) |
title |
Concentração Alveolar Mínima do Isofluorano em catetos (Tayassu tajacu, LINNAEUS, 1758) |
spellingShingle |
Concentração Alveolar Mínima do Isofluorano em catetos (Tayassu tajacu, LINNAEUS, 1758) Oliveira, Maria Gláucia Carlos de Anesthesia Wild animal Supramaximal stimulation Recovery Anestesia Animal selvagem Estímulo supramáximo Recuperação CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA |
title_short |
Concentração Alveolar Mínima do Isofluorano em catetos (Tayassu tajacu, LINNAEUS, 1758) |
title_full |
Concentração Alveolar Mínima do Isofluorano em catetos (Tayassu tajacu, LINNAEUS, 1758) |
title_fullStr |
Concentração Alveolar Mínima do Isofluorano em catetos (Tayassu tajacu, LINNAEUS, 1758) |
title_full_unstemmed |
Concentração Alveolar Mínima do Isofluorano em catetos (Tayassu tajacu, LINNAEUS, 1758) |
title_sort |
Concentração Alveolar Mínima do Isofluorano em catetos (Tayassu tajacu, LINNAEUS, 1758) |
author |
Oliveira, Maria Gláucia Carlos de |
author_facet |
Oliveira, Maria Gláucia Carlos de |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Paula, Valéria Veras de |
dc.contributor.advisor1Lattes.fl_str_mv |
http://lattes.cnpq.br/9083821440600669 |
dc.contributor.referee1.fl_str_mv |
Otsuki, Denise Aya |
dc.contributor.referee1Lattes.fl_str_mv |
http://lattes.cnpq.br/7478356557513705 |
dc.contributor.referee2.fl_str_mv |
Oliveira, Moacir Franco de |
dc.contributor.referee2Lattes.fl_str_mv |
http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4703980T5 |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/4720039078909521 |
dc.contributor.author.fl_str_mv |
Oliveira, Maria Gláucia Carlos de |
contributor_str_mv |
Paula, Valéria Veras de Otsuki, Denise Aya Oliveira, Moacir Franco de |
dc.subject.eng.fl_str_mv |
Anesthesia Wild animal Supramaximal stimulation Recovery |
topic |
Anesthesia Wild animal Supramaximal stimulation Recovery Anestesia Animal selvagem Estímulo supramáximo Recuperação CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA |
dc.subject.por.fl_str_mv |
Anestesia Animal selvagem Estímulo supramáximo Recuperação |
dc.subject.cnpq.fl_str_mv |
CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA |
description |
Inhalation anesthesia has been widespread in veterinary medicine. Nevertheless, its use in wild animals is still limited, having no studies on its use been observed in the species. The objective of the research was to determine the isoflurane minimum alveolar concentration (MAC) in peccaries and present the effects of its administration on the hemodynamic and respiratory variables, as well as data concerning the anesthesia recovery. The study used 10 male animals with age ranging from 1 to 3 years, from the Centro de Multiplicação de Animais Silvestres of Universidade Federal Rural do SemiÁrido, Brazil. All the animals had anesthesia induced with propofol 7mg.kg-1, were intubated and connected to the anesthetic circuit with isoflurane and 100% oxygen. The supramaximal noxious stimulation used was the interdigital pinch, which was performed after 15 minutes of waiting for each provided isoflurane concentration. When negative response to the stimulus was observed, the concentration was reduced by 20%; when positive response was verified, the stimulus was stopped, being the CAM value calculated from that point. Quantitative and qualitative data regarding recovery were also observed. Shapiro-Wilk test for normality was performed, as well as Levene test for equality of variance; the variables were subjected to One Way RM ANOVA for repeated measures followed by Tukey test, and the data expressed as mean and standard deviation. The MAC of isoflurane was 2.4% and the surgical MAC equal to 3.5%. Depressive action of isoflurane on blood pressure, heart and breathing rates was observed when compared to the average of the variables on awake animals; however, during maintenance of anesthesia, they remained stable. Metabolic acidosis was observed in the preanesthetic, which was offset after inhalation anesthesia. Recovery was quiet and smooth. It was concluded that the isoflurane MAC for peccaries was greater than that observed in related species. Isoflurane can be used in this species, being considered safe and effective. The animal s recovery after anesthesia with isoflurane was free from excitement |
publishDate |
2013 |
dc.date.issued.fl_str_mv |
2013-08-08 |
dc.date.accessioned.fl_str_mv |
2016-08-15T20:31:30Z |
dc.date.available.fl_str_mv |
2016-06-09 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
format |
masterThesis |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
OLIVEIRA, Maria Gláucia Carlos de. Maria Gláucia Carlos. Isoflurane minimum alveolar concentration in collared peccary (Tayassu tajacu). 2013. 84 f. Dissertação (Mestrado em Sanidade e Produção Animal) - Universidade Federal Rural do Semi-Árido, Mossoró, 2013. |
dc.identifier.uri.fl_str_mv |
https://repositorio.ufersa.edu.br/handle/tede/385 |
identifier_str_mv |
OLIVEIRA, Maria Gláucia Carlos de. Maria Gláucia Carlos. Isoflurane minimum alveolar concentration in collared peccary (Tayassu tajacu). 2013. 84 f. Dissertação (Mestrado em Sanidade e Produção Animal) - Universidade Federal Rural do Semi-Árido, Mossoró, 2013. |
url |
https://repositorio.ufersa.edu.br/handle/tede/385 |
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por |
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por |
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CC-BY-SA info:eu-repo/semantics/openAccess |
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CC-BY-SA |
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openAccess |
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Universidade Federal Rural do Semi-Árido |
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Programa de Pós-Graduação em Ciência Animal |
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UFERSA |
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BR |
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Centro de Ciências Agrárias - CCA |
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Universidade Federal Rural do Semi-Árido |
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