Função e integridade renal de cães com diabetes mellitus

Detalhes bibliográficos
Ano de defesa: 2012
Autor(a) principal: Silva, Andréa Cruvinel Rocha lattes
Orientador(a): Fioravanti, Maria Clorinda Soares lattes
Banca de defesa: Fioravanti, Maria Clorinda Soares, Kogika, Márcia Mery, Duque, Celina Tie Nishimori
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Federal de Goiás
Programa de Pós-Graduação: Programa de Pós-graduação em Ciência Animal (EVZ)
Departamento: Escola de Veterinária e Zootecnia - EVZ (RG)
País: Brasil
Palavras-chave em Português:
Caninos
Diagnóstico precoce
Doença renal crônica
Nefropatia diabética
Canine
Chronic kidney disease
Diabetic nephropathy
Early diagnosis
Área do conhecimento CNPq:
PATOLOGIA ANIMAL::PATOLOGIA CLINICA ANIMAL
Link de acesso: http://repositorio.bc.ufg.br/tede/handle/tede/3145
Resumo: Early diagnosis of diabetes mellitus (DM) in dogs or recognition of complications helps to increase the survival rate of animals. In human kidney complications caused by diabetes are well established, unlike canines. This study aimed to determine whether dogs with DM develop changes that lead to renal disease. We studied 31 diabetic dogs, which were divided into three groups, G1 realized that dogs without DR, G2, with urinary tract infection (UTI) and G3, with DR in stage 1. The evaluation consisted of history of animals, clinical examination, measurement of systolic arterial pressure (SAP) and laboratory tests: blood count, urinalysis, blood biochemistry (fibrinogen, glucose, urea, creatinine, total protein, albumin, globulin, phosphorus, calcium, sodium, potassium, fructosamine and cholesterol) and urine biochemistry (protein, creatinine, sodium, potassium and determined the activity of gama glutamiltransferase - GGT). Established the UPC and fractional excretion (EF) of sodium and potassium. The results show relation between DM and DR and the most relevant were found ITU and increase in the UPC, serum phosphorus, urinary GGT, cholesterol, fibrinogen and EF sodium and potassium. About the clinical signs observed polyuria, polydipsia, cataracts, polyphagia, weight loss, dehydration, and neoplasms. Dogs with a mean age of nine years, females, and the Poodle are more predisposed to diabetes. Dogs that have received specific diets, as well as laboratory monitoring, managed glycemic control and improved quality of life.
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spelling Fioravanti, Maria Clorinda Soareshttp://lattes.cnpq.br/8772502020076257Damasceno, Adilson DonizetiJericó, Márcia MarquesFioravanti, Maria Clorinda SoaresKogika, Márcia MeryDuque, Celina Tie Nishimorihttp://lattes.cnpq.br/0294587527449996Silva, Andréa Cruvinel Rocha2014-09-23T18:34:46Z2012-09-19SILVA, Andréa Cruvinel Rocha. Função e integridade renal de cães com diabetes mellitu. 2012. 74 f. Dissertação (Mestrado em Ciência Animal) - Universidade Federal de Goiás, Goiânia, 2012.http://repositorio.bc.ufg.br/tede/handle/tede/3145Early diagnosis of diabetes mellitus (DM) in dogs or recognition of complications helps to increase the survival rate of animals. In human kidney complications caused by diabetes are well established, unlike canines. This study aimed to determine whether dogs with DM develop changes that lead to renal disease. We studied 31 diabetic dogs, which were divided into three groups, G1 realized that dogs without DR, G2, with urinary tract infection (UTI) and G3, with DR in stage 1. The evaluation consisted of history of animals, clinical examination, measurement of systolic arterial pressure (SAP) and laboratory tests: blood count, urinalysis, blood biochemistry (fibrinogen, glucose, urea, creatinine, total protein, albumin, globulin, phosphorus, calcium, sodium, potassium, fructosamine and cholesterol) and urine biochemistry (protein, creatinine, sodium, potassium and determined the activity of gama glutamiltransferase - GGT). Established the UPC and fractional excretion (EF) of sodium and potassium. The results show relation between DM and DR and the most relevant were found ITU and increase in the UPC, serum phosphorus, urinary GGT, cholesterol, fibrinogen and EF sodium and potassium. About the clinical signs observed polyuria, polydipsia, cataracts, polyphagia, weight loss, dehydration, and neoplasms. Dogs with a mean age of nine years, females, and the Poodle are more predisposed to diabetes. Dogs that have received specific diets, as well as laboratory monitoring, managed glycemic control and improved quality of life.O diagnóstico precoce do diabetes mellitus (DM) em cães ou o reconhecimento de complicações possibilitam aumentar a taxa de sobrevida dos animais. Em humanos as complicações renais causadas pelo DM estão bem estabelecidas, diferente dos caninos. Este trabalho objetivou verificar se cães com DM desenvolvem alterações que levam à doença renal (DR). Foram estudados 31 cães diabéticos, que foram divididos em três grupos, em que G1 compreendeu os cães sem DR; G2, com infecção do trato urinário (ITU) e o G3, com DR no estádio 1. A avaliação dos animais constou de anamnese; exame clínico; mensuração da pressão arterial sistólica (PAS) e exames laboratoriais: hemograma, exame de urina, bioquímica sanguínea (fibrinogênio, glicose, uréia, creatinina, proteína total, albumina, globulina, fósforo, cálcio, sódio, potássio, frutosamina e colesterol) e bioquímica urinária (proteína, creatinina, sódio e potássio e determinada a atividade da gama glutamiltransferase - GGT). Estabeleceu-se a razão proteína:creatinina urinária (RPC) e a excreção fracional (EF) de sódio e potássio. Os resultados mostram relação entre DM e DR e as alterações mais relevantes encontradas foram ITU e aumento da RPC, do fósforo sérico, da GGT urinária, do colesterol, do fibrinogênio e da EF de sódio e potássio. E quanto aos sinais clínicos, poliúria, polidipsia, catarata, polifagia, emagrecimento, desidratação e neoplasias. Cães com idade média de nove anos, fêmeas e da raça Poodle são mais predispostos ao DM. Cães que passaram a receber dietas específicas, além da monitoração laboratorial, conseguiram o controle glicêmico e melhoria na qualidade de vida.Submitted by Marlene Santos (marlene.bc.ufg@gmail.com) on 2014-09-23T18:10:18Z No. of bitstreams: 2 Dissertacao final_MESTRADO_ANDRÉA_pdf.pdf: 1572790 bytes, checksum: 50d50dc5744b87dfbdd59a0cd86e00d3 (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5)Approved for entry into archive by Jaqueline Silva (jtas29@gmail.com) on 2014-09-23T18:34:46Z (GMT) No. of bitstreams: 2 Dissertacao final_MESTRADO_ANDRÉA_pdf.pdf: 1572790 bytes, checksum: 50d50dc5744b87dfbdd59a0cd86e00d3 (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5)Made available in DSpace on 2014-09-23T18:34:46Z (GMT). No. of bitstreams: 2 Dissertacao final_MESTRADO_ANDRÉA_pdf.pdf: 1572790 bytes, checksum: 50d50dc5744b87dfbdd59a0cd86e00d3 (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5) Previous issue date: 2012-09-19application/pdfhttp://repositorio.bc.ufg.br/tede/retrieve/8391/Dissertacao%20final_MESTRADO_ANDR%c3%89A_pdf.pdf.jpgporUniversidade Federal de GoiásPrograma de Pós-graduação em Ciência Animal (EVZ)UFGBrasilEscola de Veterinária e Zootecnia - EVZ (RG)1. ABRASS, C. K. Diabetic proteinuria: glomerular or tubular in origin? American Journal of Nephrology, Chicago, v. 4, p. 337-346, 1984. 2. ANDERSON, S.; BRENNER, B. M. Pathogenesis of diabetic glomerulopathy: hemodynamic considerations. Diabetes Metabolism Research and Reviews, Boston, v. 4, n. 2, p. 163-77, 1988. 3. BASTOS, M. G.; KIRSZTAJN, G. M. 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dc.title.por.fl_str_mv Função e integridade renal de cães com diabetes mellitus
dc.title.alternative.eng.fl_str_mv Renal function and integrity of dogs with diabetes mellitus
title Função e integridade renal de cães com diabetes mellitus
spellingShingle Função e integridade renal de cães com diabetes mellitus
Silva, Andréa Cruvinel Rocha
Caninos
Diagnóstico precoce
Doença renal crônica
Nefropatia diabética
Canine
Chronic kidney disease
Diabetic nephropathy
Early diagnosis
PATOLOGIA ANIMAL::PATOLOGIA CLINICA ANIMAL
title_short Função e integridade renal de cães com diabetes mellitus
title_full Função e integridade renal de cães com diabetes mellitus
title_fullStr Função e integridade renal de cães com diabetes mellitus
title_full_unstemmed Função e integridade renal de cães com diabetes mellitus
title_sort Função e integridade renal de cães com diabetes mellitus
author Silva, Andréa Cruvinel Rocha
author_facet Silva, Andréa Cruvinel Rocha
author_role author
dc.contributor.advisor1.fl_str_mv Fioravanti, Maria Clorinda Soares
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/8772502020076257
dc.contributor.advisor-co1.fl_str_mv Damasceno, Adilson Donizeti
dc.contributor.advisor-co2.fl_str_mv Jericó, Márcia Marques
dc.contributor.referee1.fl_str_mv Fioravanti, Maria Clorinda Soares
dc.contributor.referee2.fl_str_mv Kogika, Márcia Mery
dc.contributor.referee3.fl_str_mv Duque, Celina Tie Nishimori
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/0294587527449996
dc.contributor.author.fl_str_mv Silva, Andréa Cruvinel Rocha
contributor_str_mv Fioravanti, Maria Clorinda Soares
Damasceno, Adilson Donizeti
Jericó, Márcia Marques
Fioravanti, Maria Clorinda Soares
Kogika, Márcia Mery
Duque, Celina Tie Nishimori
dc.subject.por.fl_str_mv Caninos
Diagnóstico precoce
Doença renal crônica
Nefropatia diabética
Canine
Chronic kidney disease
Diabetic nephropathy
Early diagnosis
topic Caninos
Diagnóstico precoce
Doença renal crônica
Nefropatia diabética
Canine
Chronic kidney disease
Diabetic nephropathy
Early diagnosis
PATOLOGIA ANIMAL::PATOLOGIA CLINICA ANIMAL
dc.subject.cnpq.fl_str_mv PATOLOGIA ANIMAL::PATOLOGIA CLINICA ANIMAL
description Early diagnosis of diabetes mellitus (DM) in dogs or recognition of complications helps to increase the survival rate of animals. In human kidney complications caused by diabetes are well established, unlike canines. This study aimed to determine whether dogs with DM develop changes that lead to renal disease. We studied 31 diabetic dogs, which were divided into three groups, G1 realized that dogs without DR, G2, with urinary tract infection (UTI) and G3, with DR in stage 1. The evaluation consisted of history of animals, clinical examination, measurement of systolic arterial pressure (SAP) and laboratory tests: blood count, urinalysis, blood biochemistry (fibrinogen, glucose, urea, creatinine, total protein, albumin, globulin, phosphorus, calcium, sodium, potassium, fructosamine and cholesterol) and urine biochemistry (protein, creatinine, sodium, potassium and determined the activity of gama glutamiltransferase - GGT). Established the UPC and fractional excretion (EF) of sodium and potassium. The results show relation between DM and DR and the most relevant were found ITU and increase in the UPC, serum phosphorus, urinary GGT, cholesterol, fibrinogen and EF sodium and potassium. About the clinical signs observed polyuria, polydipsia, cataracts, polyphagia, weight loss, dehydration, and neoplasms. Dogs with a mean age of nine years, females, and the Poodle are more predisposed to diabetes. Dogs that have received specific diets, as well as laboratory monitoring, managed glycemic control and improved quality of life.
publishDate 2012
dc.date.issued.fl_str_mv 2012-09-19
dc.date.accessioned.fl_str_mv 2014-09-23T18:34:46Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.citation.fl_str_mv SILVA, Andréa Cruvinel Rocha. Função e integridade renal de cães com diabetes mellitu. 2012. 74 f. Dissertação (Mestrado em Ciência Animal) - Universidade Federal de Goiás, Goiânia, 2012.
dc.identifier.uri.fl_str_mv http://repositorio.bc.ufg.br/tede/handle/tede/3145
identifier_str_mv SILVA, Andréa Cruvinel Rocha. Função e integridade renal de cães com diabetes mellitu. 2012. 74 f. Dissertação (Mestrado em Ciência Animal) - Universidade Federal de Goiás, Goiânia, 2012.
url http://repositorio.bc.ufg.br/tede/handle/tede/3145
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