Análise endotelial da córnea em pacientes submetidos à cirurgia corneal pela técnica de anel intraestromal

• Ano de defesa: 2012
• Autor(a) principal: SILVA, Rodrigo Salustiano Corrêa e
• Orientador(a): ÁVILA, Marcos Pereira de
• Tipo de documento: Tese
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de Goiás
• Programa de Pós-Graduação: Doutorado em Ciencias da Saude
• Departamento: Ciencias da Saude
• País: BR
• Palavras-chave em Português: ceratocone; anel intraestromal; microscopia especular; coeficiente de variação; percentual de células hexagonais
• Palavras-chave em Inglês: keratoconus; intraestromal ring; specular microscopy; coefficients of variation; percentage of hexagonal cells
• Área do conhecimento CNPq: CNPQ::CIENCIAS DA SAUDE::MEDICINA::CLINICA MEDICA
• Link de acesso: http://repositorio.bc.ufg.br/tede/handle/tde/1546

To evaluate corneal endothelium by means of specular microscopy exam in patients with keratoconus, before and after Cornealring® corneal intrastromal ring surgery. A hundred and two eyes of sixty-seven patients, aged between 12 and 45, with the average age of 27,31 ± 8,15 years, 30 of whom females and 37 males, were selected to be submitted to the implant of Cornealring® corneal ring segments and evaluation of the corneal endothelium in the pre and post surgery (six months after the procedure) in the External Diseases and Cornea Ward of the Instituto Panamericano da Visão. Data have been stored for later analysis by software SPSS (Statistical Package of Social Science) for Windows 15.0. Only the eyes receiving two rings with 250 μ thickness showed significant statistical difference (p = 0,008). The remaining eyes showed no statistical difference (initial x final). In relation to the thickness and to the number of implanted rings, a decrease in the final coefficient was observed in most implanted rings. However, only the eyes that received two rings 250 μ thick showed significant difference (p=0,003), with a decrease of 10,1% in the coefficients of variation average. In relation to the thickness and number of implanted rings, a decrease in the percentage of hexagonal cells was observed (before and after surgery). Only the eyes that received two rings 250 μ thick showed a highly significant decrease (p=0,001) in relation to the hexagonal percentage of 9,7%. Although the parameters in the specular microscopy showed alterations mainly in the thicker rings, all the patients showed transparent corneas without clinical signs of endothelial suffering along the six months of follow-up. A longer period of study must be considered for better understanding and interpretation of the results obtained, in order to establish any relationship between eventual complications and the thickness of the implanted ring.