Injúria renal aguda em cadelas com piometra: a importância do diagnóstico precoce

Detalhes bibliográficos
Ano de defesa: 2019
Autor(a) principal: Ribeiro, Luana de Sousa lattes
Orientador(a): Martins, Danieli Brolo lattes
Banca de defesa: Crivellenti, Leandro Zuccolotto, Borges, Naida Cristina, Martins, Danieli Brolo
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
dARK ID: ark:/38995/001300000bb0d
Idioma: por
Instituição de defesa: Universidade Federal de Goiás
Programa de Pós-Graduação: Programa de Pós-graduação em Ciência Animal (EVZ)
Departamento: Escola de Veterinária e Zootecnia - EVZ (RG)
País: Brasil
Palavras-chave em Português:
Canino
Doppler pulsado
Injúria renal aguda
Dimetil-arginina simétrica
Relação proteína creatinina urinária
Palavras-chave em Inglês:
Canine
Pulsed doppler
Acute renal injury
Symmetrical dimethylarginine
Urinary protein-to-creatinine ratio
Área do conhecimento CNPq:
PATOLOGIA ANIMAL::PATOLOGIA CLINICA ANIMAL
Link de acesso: http://repositorio.bc.ufg.br/tede/handle/tede/9886
Resumo: Acute renal injury (ARF) causes the prognosis of female dogs with pyometra to be reserved, with a greater probability of death. The diagnosis of this complication is a challenge for the veterinarian because the disease is clinically silent. In this sense, the use of laboratory and ultrasonographic exams helps to detect the initial phase of the disease. Therefore, this article had the objective to evaluate the symmetrical dimethylarginine (SDMA) as an early biomarker in an acute kidney cells injury in female dogs with pyometra. To do this, nine animals with pyometra without renal azotemia, but with diagnosed acute renal insufficiency (ARI) by the resistivity (RI) and pulsability (PI) indexes in color Doppler and pulse modes, where compared to 10 healthy animals submitted to elective ovarianhisterectomie (OSH). The results were compared with other laboratory indicators of impairment of the kidneys in non-azotemic renal animals. It is concluded from the data obtained that the relation protein/urinary creatinine (RPCU) is more precocious than SDMA, which makes it the laboratory analysis of choice for the detection of ARI in dogs with pyometra.
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spelling Martins, Danieli Brolohttp://lattes.cnpq.br/2159963349521553Silva, Carla Afonsohttp://lattes.cnpq.br/7673897995590123Lima, Aline Maria Vasconceloshttp://lattes.cnpq.br/9400081245263251Crivellenti, Leandro ZuccolottoBorges, Naida CristinaMartins, Danieli Brolohttp://lattes.cnpq.br/0466042867131499Ribeiro, Luana de Sousa2019-08-02T14:20:58Z2019-06-05RIBEIRO, L. S. Injúria renal aguda em cadelas com piometra: a importância do diagnóstico precoce. 2019. 40 f. Dissertação (Mestrado em Ciência Animal) - Universidade Federal de Goiás, Goiânia, 2019.http://repositorio.bc.ufg.br/tede/handle/tede/9886ark:/38995/001300000bb0dAcute renal injury (ARF) causes the prognosis of female dogs with pyometra to be reserved, with a greater probability of death. The diagnosis of this complication is a challenge for the veterinarian because the disease is clinically silent. In this sense, the use of laboratory and ultrasonographic exams helps to detect the initial phase of the disease. Therefore, this article had the objective to evaluate the symmetrical dimethylarginine (SDMA) as an early biomarker in an acute kidney cells injury in female dogs with pyometra. To do this, nine animals with pyometra without renal azotemia, but with diagnosed acute renal insufficiency (ARI) by the resistivity (RI) and pulsability (PI) indexes in color Doppler and pulse modes, where compared to 10 healthy animals submitted to elective ovarianhisterectomie (OSH). The results were compared with other laboratory indicators of impairment of the kidneys in non-azotemic renal animals. It is concluded from the data obtained that the relation protein/urinary creatinine (RPCU) is more precocious than SDMA, which makes it the laboratory analysis of choice for the detection of ARI in dogs with pyometra.A injúria renal aguda (IRA) faz com que o prognóstico de cadelas com piometra passe a ser reservado, com maior probabilidade de óbito. O diagnóstico dessa complicação nos rins é um desafio para o clínico veterinário, pois a doença é clinicamente silenciosa. Nesse sentido, o uso de exames laboratoriais e ultrassonografia auxiliam na detecção da fase inicial da doença. Portanto, o presente trabalho teve por objetivo avaliar a dimetil-arginina simétrica (SDMA) como biomarcador precoce em lesão renal aguda de cadelas com piometra. Para tanto, comparou-se nove animais com piometra sem azotemia renal, mas com diagnóstico de IRA pelos índices de resistividade (IR) e pulsabilidade (IP) em modo Doppler colorido e pulsado no ultrassom, com 10 animais hígidos submetidos a ovariohisterectomia (OSH) eletiva. Os resultados foram confrontados com outros parâmetros laboratoriais indicadores de comprometimento funcional dos rins, em animais não azotêmicos renais. Concluiu-se, a partir dos dados obtidos, que a relação proteína creatinina urinária (RPCU) é mais precoce que a SDMA, o que a torna a análise laboratorial de escolha para a detecção de IRA em cadelas com piometra.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPESapplication/pdfporUniversidade Federal de GoiásPrograma de Pós-graduação em Ciência Animal (EVZ)UFGBrasilEscola de Veterinária e Zootecnia - EVZ (RG)http://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessCaninoDoppler pulsadoInjúria renal agudaDimetil-arginina simétricaRelação proteína creatinina urináriaCaninePulsed dopplerAcute renal injurySymmetrical dimethylarginineUrinary protein-to-creatinine ratioPATOLOGIA ANIMAL::PATOLOGIA CLINICA ANIMALInjúria renal aguda em cadelas com piometra: a importância do diagnóstico precoceAcute renal injury in bitches with pyometra: the importance of early diagnosisinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesis4581960685150189167600600600600-62175521142490945826109832347911310612075167498588264571reponame:Repositório Institucional da UFGinstname:Universidade Federal de Goiás (UFG)instacron:UFGLICENSElicense.txtlicense.txttext/plain; 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dc.title.eng.fl_str_mv Injúria renal aguda em cadelas com piometra: a importância do diagnóstico precoce
dc.title.alternative.eng.fl_str_mv Acute renal injury in bitches with pyometra: the importance of early diagnosis
title Injúria renal aguda em cadelas com piometra: a importância do diagnóstico precoce
spellingShingle Injúria renal aguda em cadelas com piometra: a importância do diagnóstico precoce
Ribeiro, Luana de Sousa
Canino
Doppler pulsado
Injúria renal aguda
Dimetil-arginina simétrica
Relação proteína creatinina urinária
Canine
Pulsed doppler
Acute renal injury
Symmetrical dimethylarginine
Urinary protein-to-creatinine ratio
PATOLOGIA ANIMAL::PATOLOGIA CLINICA ANIMAL
title_short Injúria renal aguda em cadelas com piometra: a importância do diagnóstico precoce
title_full Injúria renal aguda em cadelas com piometra: a importância do diagnóstico precoce
title_fullStr Injúria renal aguda em cadelas com piometra: a importância do diagnóstico precoce
title_full_unstemmed Injúria renal aguda em cadelas com piometra: a importância do diagnóstico precoce
title_sort Injúria renal aguda em cadelas com piometra: a importância do diagnóstico precoce
author Ribeiro, Luana de Sousa
author_facet Ribeiro, Luana de Sousa
author_role author
dc.contributor.advisor1.fl_str_mv Martins, Danieli Brolo
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/2159963349521553
dc.contributor.advisor-co1.fl_str_mv Silva, Carla Afonso
dc.contributor.advisor-co1Lattes.fl_str_mv http://lattes.cnpq.br/7673897995590123
dc.contributor.advisor-co2.fl_str_mv Lima, Aline Maria Vasconcelos
dc.contributor.advisor-co2Lattes.fl_str_mv http://lattes.cnpq.br/9400081245263251
dc.contributor.referee1.fl_str_mv Crivellenti, Leandro Zuccolotto
dc.contributor.referee2.fl_str_mv Borges, Naida Cristina
dc.contributor.referee3.fl_str_mv Martins, Danieli Brolo
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/0466042867131499
dc.contributor.author.fl_str_mv Ribeiro, Luana de Sousa
contributor_str_mv Martins, Danieli Brolo
Silva, Carla Afonso
Lima, Aline Maria Vasconcelos
Crivellenti, Leandro Zuccolotto
Borges, Naida Cristina
Martins, Danieli Brolo
dc.subject.por.fl_str_mv Canino
Doppler pulsado
Injúria renal aguda
Dimetil-arginina simétrica
Relação proteína creatinina urinária
topic Canino
Doppler pulsado
Injúria renal aguda
Dimetil-arginina simétrica
Relação proteína creatinina urinária
Canine
Pulsed doppler
Acute renal injury
Symmetrical dimethylarginine
Urinary protein-to-creatinine ratio
PATOLOGIA ANIMAL::PATOLOGIA CLINICA ANIMAL
dc.subject.eng.fl_str_mv Canine
Pulsed doppler
Acute renal injury
Symmetrical dimethylarginine
Urinary protein-to-creatinine ratio
dc.subject.cnpq.fl_str_mv PATOLOGIA ANIMAL::PATOLOGIA CLINICA ANIMAL
description Acute renal injury (ARF) causes the prognosis of female dogs with pyometra to be reserved, with a greater probability of death. The diagnosis of this complication is a challenge for the veterinarian because the disease is clinically silent. In this sense, the use of laboratory and ultrasonographic exams helps to detect the initial phase of the disease. Therefore, this article had the objective to evaluate the symmetrical dimethylarginine (SDMA) as an early biomarker in an acute kidney cells injury in female dogs with pyometra. To do this, nine animals with pyometra without renal azotemia, but with diagnosed acute renal insufficiency (ARI) by the resistivity (RI) and pulsability (PI) indexes in color Doppler and pulse modes, where compared to 10 healthy animals submitted to elective ovarianhisterectomie (OSH). The results were compared with other laboratory indicators of impairment of the kidneys in non-azotemic renal animals. It is concluded from the data obtained that the relation protein/urinary creatinine (RPCU) is more precocious than SDMA, which makes it the laboratory analysis of choice for the detection of ARI in dogs with pyometra.
publishDate 2019
dc.date.accessioned.fl_str_mv 2019-08-02T14:20:58Z
dc.date.issued.fl_str_mv 2019-06-05
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.citation.fl_str_mv RIBEIRO, L. S. Injúria renal aguda em cadelas com piometra: a importância do diagnóstico precoce. 2019. 40 f. Dissertação (Mestrado em Ciência Animal) - Universidade Federal de Goiás, Goiânia, 2019.
dc.identifier.uri.fl_str_mv http://repositorio.bc.ufg.br/tede/handle/tede/9886
dc.identifier.dark.fl_str_mv ark:/38995/001300000bb0d
identifier_str_mv RIBEIRO, L. S. Injúria renal aguda em cadelas com piometra: a importância do diagnóstico precoce. 2019. 40 f. Dissertação (Mestrado em Ciência Animal) - Universidade Federal de Goiás, Goiânia, 2019.
ark:/38995/001300000bb0d
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dc.publisher.none.fl_str_mv Universidade Federal de Goiás
dc.publisher.program.fl_str_mv Programa de Pós-graduação em Ciência Animal (EVZ)
dc.publisher.initials.fl_str_mv UFG
dc.publisher.country.fl_str_mv Brasil
dc.publisher.department.fl_str_mv Escola de Veterinária e Zootecnia - EVZ (RG)
publisher.none.fl_str_mv Universidade Federal de Goiás
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