Síntese de compostos heteroazóicos substituídos no solvente alternativo PEG 400

Detalhes bibliográficos
Ano de defesa: 2018
Autor(a) principal: Ferreira, Achiles Silva lattes
Orientador(a): Barros, Olga Soares do Rêgo lattes
Banca de defesa: Barros, Olga Soares do Rêgo lattes, Chagas, Rafael Pavão das, Milani, Jorge Luiz Sônego, Costa, Maisa Borges
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
dARK ID: ark:/38995/0013000005t8t
Idioma: por
Instituição de defesa: Universidade Federal de Goiás
Programa de Pós-Graduação: Programa de Pós-graduação em Química (IQ)
Departamento: Instituto de Química - IQ (RG)
País: Brasil
Palavras-chave em Português:
Síntese
Heterocíclicos
Palavras-chave em Inglês:
Synthesis
Heterocyclics
Área do conhecimento CNPq:
QUIMICA::QUIMICA ORGANICA
Link de acesso: http://repositorio.bc.ufg.br/tede/handle/tede/8679
Resumo: The present work describes the development of a simple and efficient methodology for the synthesis of 2-aminoheteroazoic compounds using the solvent PEG 400 as an alternative to toxic and flammable organic solvents. Several media and reactional conditions were compared. A series of substituted 2-aminothiazoic compounds was obtained in good yields (60 to 96%) by a 3 hour reaction procedure using PEG 400 at room temperature and without the need for additives or catalysts. A selenium analogue and a 2-imino-1,3-thiazoline were also obtained by this method. The products were characterized by 1H and 13C NMR and infrared spectroscopies and mass spectrometry. The method covers some points of Green Chemistry, such as: safe synthesis, prevention in the formation of residues or derivatives, development of products that do not harm the environment, energy efficiency and accident prevention.
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spelling Barros, Olga Soares do Rêgohttp://lattes.cnpq.br/8311808341863723Chagas, Rafael Pavão dashttp://lattes.cnpq.br/9712618482518275Barros, Olga Soares do Rêgohttp://lattes.cnpq.br/8311808341863723Chagas, Rafael Pavão dasMilani, Jorge Luiz SônegoCosta, Maisa Borgeshttp://lattes.cnpq.br/7794429925120494Ferreira, Achiles Silva2018-07-11T10:40:15Z2018-04-27FERREIRA, A. S. Síntese de compostos heteroazóicos substituídos no solvente alternativo PEG 400. 2018. 76 f. Dissertação (Mestrado em Química) - Universidade Federal de Goiás, Goiânia, 2018.http://repositorio.bc.ufg.br/tede/handle/tede/8679ark:/38995/0013000005t8tThe present work describes the development of a simple and efficient methodology for the synthesis of 2-aminoheteroazoic compounds using the solvent PEG 400 as an alternative to toxic and flammable organic solvents. Several media and reactional conditions were compared. A series of substituted 2-aminothiazoic compounds was obtained in good yields (60 to 96%) by a 3 hour reaction procedure using PEG 400 at room temperature and without the need for additives or catalysts. A selenium analogue and a 2-imino-1,3-thiazoline were also obtained by this method. The products were characterized by 1H and 13C NMR and infrared spectroscopies and mass spectrometry. The method covers some points of Green Chemistry, such as: safe synthesis, prevention in the formation of residues or derivatives, development of products that do not harm the environment, energy efficiency and accident prevention.O presente trabalho descreve o desenvolvimento de uma metodologia simples e eficiente para a síntese de compostos 2-amino-heteroazóicos, utilizando o solvente PEG 400 como alternativa a solventes orgânicos tóxicos e inflamáveis. Diversos meios e condições reacionais foram comparados. Uma série de compostos 2-amino-tioazóicos substituídos foi obtida, em bons rendimentos (60 a 96%), através de procedimento reacional com 3 horas de duração, utilizando PEG 400 à temperatura ambiente e sem a necessidade de aditivos ou catalisadores. Um análogo de selênio e uma 2-imino-1,3-tiazolina também foram obtidos através desse método. Os produtos foram caracterizados por espectroscopias de RMN de 1H e 13C e infravermelho e espectrometria de massas. O método abrange alguns pontos da Química Verde, como: síntese segura, prevenção na formação de resíduos ou derivados, desenvolvimento de produtos que não agridem o meio ambiente, eficiência energética e prevenção de acidentes.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPESapplication/pdfporUniversidade Federal de GoiásPrograma de Pós-graduação em Química (IQ)UFGBrasilInstituto de Química - IQ (RG)http://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessSínteseHeterocíclicosSynthesisHeterocyclicsQUIMICA::QUIMICA ORGANICASíntese de compostos heteroazóicos substituídos no solvente alternativo PEG 400Synthesis of heteroazo compounds in alternative solvent PEG 400info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesis6636939213254151586006006006007826066743741197278-81940697172828021542075167498588264571reponame:Repositório Institucional da UFGinstname:Universidade Federal de Goiás (UFG)instacron:UFGORIGINALDissertação - Achiles Silva Ferreira - 2018.pdfDissertação - Achiles Silva Ferreira - 2018.pdfapplication/pdf3183279http://repositorio.bc.ufg.br/tede/bitstreams/6f29713c-89b4-4379-afbb-522c1cb21dee/download59976d2d13952581ed03b3a3f2983a22MD55LICENSElicense.txtlicense.txttext/plain; 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dc.title.eng.fl_str_mv Síntese de compostos heteroazóicos substituídos no solvente alternativo PEG 400
dc.title.alternative.eng.fl_str_mv Synthesis of heteroazo compounds in alternative solvent PEG 400
title Síntese de compostos heteroazóicos substituídos no solvente alternativo PEG 400
spellingShingle Síntese de compostos heteroazóicos substituídos no solvente alternativo PEG 400
Ferreira, Achiles Silva
Síntese
Heterocíclicos
Synthesis
Heterocyclics
QUIMICA::QUIMICA ORGANICA
title_short Síntese de compostos heteroazóicos substituídos no solvente alternativo PEG 400
title_full Síntese de compostos heteroazóicos substituídos no solvente alternativo PEG 400
title_fullStr Síntese de compostos heteroazóicos substituídos no solvente alternativo PEG 400
title_full_unstemmed Síntese de compostos heteroazóicos substituídos no solvente alternativo PEG 400
title_sort Síntese de compostos heteroazóicos substituídos no solvente alternativo PEG 400
author Ferreira, Achiles Silva
author_facet Ferreira, Achiles Silva
author_role author
dc.contributor.advisor1.fl_str_mv Barros, Olga Soares do Rêgo
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/8311808341863723
dc.contributor.advisor-co1.fl_str_mv Chagas, Rafael Pavão das
dc.contributor.advisor-co1Lattes.fl_str_mv http://lattes.cnpq.br/9712618482518275
dc.contributor.referee1.fl_str_mv Barros, Olga Soares do Rêgo
dc.contributor.referee1Lattes.fl_str_mv http://lattes.cnpq.br/8311808341863723
dc.contributor.referee2.fl_str_mv Chagas, Rafael Pavão das
dc.contributor.referee3.fl_str_mv Milani, Jorge Luiz Sônego
dc.contributor.referee4.fl_str_mv Costa, Maisa Borges
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/7794429925120494
dc.contributor.author.fl_str_mv Ferreira, Achiles Silva
contributor_str_mv Barros, Olga Soares do Rêgo
Chagas, Rafael Pavão das
Barros, Olga Soares do Rêgo
Chagas, Rafael Pavão das
Milani, Jorge Luiz Sônego
Costa, Maisa Borges
dc.subject.por.fl_str_mv Síntese
Heterocíclicos
topic Síntese
Heterocíclicos
Synthesis
Heterocyclics
QUIMICA::QUIMICA ORGANICA
dc.subject.eng.fl_str_mv Synthesis
Heterocyclics
dc.subject.cnpq.fl_str_mv QUIMICA::QUIMICA ORGANICA
description The present work describes the development of a simple and efficient methodology for the synthesis of 2-aminoheteroazoic compounds using the solvent PEG 400 as an alternative to toxic and flammable organic solvents. Several media and reactional conditions were compared. A series of substituted 2-aminothiazoic compounds was obtained in good yields (60 to 96%) by a 3 hour reaction procedure using PEG 400 at room temperature and without the need for additives or catalysts. A selenium analogue and a 2-imino-1,3-thiazoline were also obtained by this method. The products were characterized by 1H and 13C NMR and infrared spectroscopies and mass spectrometry. The method covers some points of Green Chemistry, such as: safe synthesis, prevention in the formation of residues or derivatives, development of products that do not harm the environment, energy efficiency and accident prevention.
publishDate 2018
dc.date.accessioned.fl_str_mv 2018-07-11T10:40:15Z
dc.date.issued.fl_str_mv 2018-04-27
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
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status_str publishedVersion
dc.identifier.citation.fl_str_mv FERREIRA, A. S. Síntese de compostos heteroazóicos substituídos no solvente alternativo PEG 400. 2018. 76 f. Dissertação (Mestrado em Química) - Universidade Federal de Goiás, Goiânia, 2018.
dc.identifier.uri.fl_str_mv http://repositorio.bc.ufg.br/tede/handle/tede/8679
dc.identifier.dark.fl_str_mv ark:/38995/0013000005t8t
identifier_str_mv FERREIRA, A. S. Síntese de compostos heteroazóicos substituídos no solvente alternativo PEG 400. 2018. 76 f. Dissertação (Mestrado em Química) - Universidade Federal de Goiás, Goiânia, 2018.
ark:/38995/0013000005t8t
url http://repositorio.bc.ufg.br/tede/handle/tede/8679
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language por
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dc.publisher.country.fl_str_mv Brasil
dc.publisher.department.fl_str_mv Instituto de Química - IQ (RG)
publisher.none.fl_str_mv Universidade Federal de Goiás
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