Indicadores de alterações auditivas em crianças com síndrome congênita do Zika vírus
| Ano de defesa: | 2020 |
|---|---|
| Autor(a) principal: | |
| Orientador(a): | |
| Banca de defesa: | , , |
| Tipo de documento: | Dissertação |
| Tipo de acesso: | Acesso aberto |
| Idioma: | por |
| Instituição de defesa: |
Universidade Federal de Goiás
|
| Programa de Pós-Graduação: |
Programa de Pós-graduação em Ciências da Saúde (FM)
|
| Departamento: |
Faculdade de Medicina - FM (RG)
|
| País: |
Brasil
|
| Palavras-chave em Português: | |
| Palavras-chave em Inglês: | |
| Área do conhecimento CNPq: | |
| Link de acesso: | http://repositorio.bc.ufg.br/tede/handle/tede/10862 |
Resumo: | Congenital Zika Syndrome is the result of congenital anomalies caused by Zika virus infection by vertical transmission. It is a clinical spectrum ranging from asymptomatic patients to syndromic manifestations. The aim of the study was to evaluate the risk indicators for hearing impairment in children with Congenital Zika Virus Syndrome treated at the Rehabilitation and Rehabilitation Center Dr. Henrique Santillo, from January 2015 to October 2019. The data of the clinical examination and the results of the audiological examinations were obtained by assisting patients referred to the multidisciplinary rehabilitation service by an otorhinolaryngologist. These data were presented in simple frequency. Fisher's Exact test was used at statistical analysis to assess whether the presence of another risk indicator for hearing loss was determinant in the occurrence of the hearing impairment found. For the conclusion regarding the test, the 95% confidence level was set. The most prevalent risk indicator for hearing loss in this population was neonatal jaundice. The prevalence of hearing disorders in children with ZIKV infection was 17.91% with an estimated 17.9:1000 children. These changes were not better justified by the presence of another risk indicator for hearing loss in addition to Zika virus infection. Longitudinal follow-up studies are suggested to assess the potential effects of the interaction between the virus and the host as a progressive worsening of hearing loss or the appearance of late hearing loss. |
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Guimarães, Valeriana de Castrohttp://lattes.cnpq.br/6222102545181441Guimarães, Valeriana de CastroTorres, Lisa Valéria VieiraSilva, Maria Sebastianahttp://lattes.cnpq.br/9754469497103231Daher, Valéria Barcelos2020-10-15T12:07:44Z2020-10-15T12:07:44Z2020-08-28DAHER, V. B. Indicadores de alterações auditivas em crianças com síndrome congênita do Zika vírus. 2020. 73 f. Dissertação (Mestrado em Ciências da Saúde) - Universidade Federal de Goiás, Goiânia, 2020.http://repositorio.bc.ufg.br/tede/handle/tede/10862Congenital Zika Syndrome is the result of congenital anomalies caused by Zika virus infection by vertical transmission. It is a clinical spectrum ranging from asymptomatic patients to syndromic manifestations. The aim of the study was to evaluate the risk indicators for hearing impairment in children with Congenital Zika Virus Syndrome treated at the Rehabilitation and Rehabilitation Center Dr. Henrique Santillo, from January 2015 to October 2019. The data of the clinical examination and the results of the audiological examinations were obtained by assisting patients referred to the multidisciplinary rehabilitation service by an otorhinolaryngologist. These data were presented in simple frequency. Fisher's Exact test was used at statistical analysis to assess whether the presence of another risk indicator for hearing loss was determinant in the occurrence of the hearing impairment found. For the conclusion regarding the test, the 95% confidence level was set. The most prevalent risk indicator for hearing loss in this population was neonatal jaundice. The prevalence of hearing disorders in children with ZIKV infection was 17.91% with an estimated 17.9:1000 children. These changes were not better justified by the presence of another risk indicator for hearing loss in addition to Zika virus infection. Longitudinal follow-up studies are suggested to assess the potential effects of the interaction between the virus and the host as a progressive worsening of hearing loss or the appearance of late hearing loss.A Síndrome Congênita do Zika Vírus é o resultado de anomalias congênitas pela infecção por Zika vírus, por transmissão vertical, com espectro clínico que varia de pacientes assintomáticos às manifestações sindrômicas. O objetivo deste estudo foi avaliar os indicadores de risco para deficiência auditiva em crianças com Síndrome Congênita do Zika Vírus atendidas no Centro de Reabilitação e Readaptação Dr. Henrique Santillo, no período de janeiro de 2015 a outubro de 2019. Os dados do exame clínico e os resultados dos exames audiológicos foram obtidos através da assistência aos pacientes encaminhados ao serviço multidisciplinar de reabilitação por médico otorrinolaringologista. Estes dados foram apresentados em frequência simples. O teste Exato de Fisher foi utilizado na análise estatística para avaliação se a presença de outro indicador de risco para deficiência auditiva além da infecção pelo Zika vírus foi determinante na ocorrência da alteração auditiva encontrada. Para a conclusão quanto ao teste, fixou-se o nível de 95% de confiança. O indicador de risco para deficiência auditiva mais prevalente nesta população foi a icterícia neonatal. A prevalência de alterações auditivas em crianças com infecção pelo ZIKV foi de 17,91%. Essas alterações não foram melhores justificados pela presença de outro indicador de risco para deficiência auditiva além da infecção pelo Zika vírus. Sugere-se estudos de seguimento longitudinal para avaliar os potenciais efeitos da interação entre o vírus e o hospedeiro como uma piora progressiva da perda auditiva ou o surgimento de perda auditiva tardia.porUniversidade Federal de GoiásPrograma de Pós-graduação em Ciências da Saúde (FM)UFGBrasilFaculdade de Medicina - FM (RG)Attribution-NonCommercial-NoDerivatives 4.0 Internationalinfo:eu-repo/semantics/openAccessZika vírusSurdezMicrocefaliaCriançaMicrocephalyDeafnessChildZika vírusCIENCIAS DA SAUDEIndicadores de alterações auditivas em crianças com síndrome congênita do Zika vírusHearing impairment indicators in children with congenital Zika virus syndromeinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesis2450050050019182reponame:Repositório Institucional da UFGinstname:Universidade Federal de Goiás (UFG)instacron:UFGLICENSElicense.txtlicense.txttext/plain; charset=utf-81748http://repositorio.bc.ufg.br/tede/bitstreams/5a7bed40-f66a-4f63-810a-3eb94412805a/download8a4605be74aa9ea9d79846c1fba20a33MD51CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8805http://repositorio.bc.ufg.br/tede/bitstreams/36604bbc-ea08-46fc-be66-8b09e640bfcd/download4460e5956bc1d1639be9ae6146a50347MD52ORIGINALDissertação - Valéria Barcelos Daher - 2020.pdfDissertação - Valéria Barcelos Daher - 2020.pdfapplication/pdf7369520http://repositorio.bc.ufg.br/tede/bitstreams/7f625ca3-c502-470a-9f71-06bb988d7f6d/downloadacdd68129d7b4c0927418d418fc04198MD53tede/108622020-10-15 09:07:44.615http://creativecommons.org/licenses/by-nc-nd/4.0/Attribution-NonCommercial-NoDerivatives 4.0 Internationalopen.accessoai:repositorio.bc.ufg.br:tede/10862http://repositorio.bc.ufg.br/tedeRepositório InstitucionalPUBhttps://repositorio.bc.ufg.br/tedeserver/oai/requestgrt.bc@ufg.bropendoar:oai:repositorio.bc.ufg.br:tede/12342020-10-15T12:07:44Repositório Institucional da UFG - Universidade Federal de Goiás (UFG)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 |
| dc.title.pt_BR.fl_str_mv |
Indicadores de alterações auditivas em crianças com síndrome congênita do Zika vírus |
| dc.title.alternative.eng.fl_str_mv |
Hearing impairment indicators in children with congenital Zika virus syndrome |
| title |
Indicadores de alterações auditivas em crianças com síndrome congênita do Zika vírus |
| spellingShingle |
Indicadores de alterações auditivas em crianças com síndrome congênita do Zika vírus Daher, Valéria Barcelos Zika vírus Surdez Microcefalia Criança Microcephaly Deafness Child Zika vírus CIENCIAS DA SAUDE |
| title_short |
Indicadores de alterações auditivas em crianças com síndrome congênita do Zika vírus |
| title_full |
Indicadores de alterações auditivas em crianças com síndrome congênita do Zika vírus |
| title_fullStr |
Indicadores de alterações auditivas em crianças com síndrome congênita do Zika vírus |
| title_full_unstemmed |
Indicadores de alterações auditivas em crianças com síndrome congênita do Zika vírus |
| title_sort |
Indicadores de alterações auditivas em crianças com síndrome congênita do Zika vírus |
| author |
Daher, Valéria Barcelos |
| author_facet |
Daher, Valéria Barcelos |
| author_role |
author |
| dc.contributor.advisor1.fl_str_mv |
Guimarães, Valeriana de Castro |
| dc.contributor.advisor1Lattes.fl_str_mv |
http://lattes.cnpq.br/6222102545181441 |
| dc.contributor.referee1.fl_str_mv |
Guimarães, Valeriana de Castro |
| dc.contributor.referee2.fl_str_mv |
Torres, Lisa Valéria Vieira |
| dc.contributor.referee3.fl_str_mv |
Silva, Maria Sebastiana |
| dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/9754469497103231 |
| dc.contributor.author.fl_str_mv |
Daher, Valéria Barcelos |
| contributor_str_mv |
Guimarães, Valeriana de Castro Guimarães, Valeriana de Castro Torres, Lisa Valéria Vieira Silva, Maria Sebastiana |
| dc.subject.por.fl_str_mv |
Zika vírus Surdez Microcefalia Criança |
| topic |
Zika vírus Surdez Microcefalia Criança Microcephaly Deafness Child Zika vírus CIENCIAS DA SAUDE |
| dc.subject.eng.fl_str_mv |
Microcephaly Deafness Child Zika vírus |
| dc.subject.cnpq.fl_str_mv |
CIENCIAS DA SAUDE |
| description |
Congenital Zika Syndrome is the result of congenital anomalies caused by Zika virus infection by vertical transmission. It is a clinical spectrum ranging from asymptomatic patients to syndromic manifestations. The aim of the study was to evaluate the risk indicators for hearing impairment in children with Congenital Zika Virus Syndrome treated at the Rehabilitation and Rehabilitation Center Dr. Henrique Santillo, from January 2015 to October 2019. The data of the clinical examination and the results of the audiological examinations were obtained by assisting patients referred to the multidisciplinary rehabilitation service by an otorhinolaryngologist. These data were presented in simple frequency. Fisher's Exact test was used at statistical analysis to assess whether the presence of another risk indicator for hearing loss was determinant in the occurrence of the hearing impairment found. For the conclusion regarding the test, the 95% confidence level was set. The most prevalent risk indicator for hearing loss in this population was neonatal jaundice. The prevalence of hearing disorders in children with ZIKV infection was 17.91% with an estimated 17.9:1000 children. These changes were not better justified by the presence of another risk indicator for hearing loss in addition to Zika virus infection. Longitudinal follow-up studies are suggested to assess the potential effects of the interaction between the virus and the host as a progressive worsening of hearing loss or the appearance of late hearing loss. |
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2020 |
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2020-10-15T12:07:44Z |
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2020-10-15T12:07:44Z |
| dc.date.issued.fl_str_mv |
2020-08-28 |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/masterThesis |
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publishedVersion |
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DAHER, V. B. Indicadores de alterações auditivas em crianças com síndrome congênita do Zika vírus. 2020. 73 f. Dissertação (Mestrado em Ciências da Saúde) - Universidade Federal de Goiás, Goiânia, 2020. |
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http://repositorio.bc.ufg.br/tede/handle/tede/10862 |
| identifier_str_mv |
DAHER, V. B. Indicadores de alterações auditivas em crianças com síndrome congênita do Zika vírus. 2020. 73 f. Dissertação (Mestrado em Ciências da Saúde) - Universidade Federal de Goiás, Goiânia, 2020. |
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http://repositorio.bc.ufg.br/tede/handle/tede/10862 |
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por |
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por |
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24 |
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500 500 500 |
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19 |
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182 |
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Attribution-NonCommercial-NoDerivatives 4.0 International info:eu-repo/semantics/openAccess |
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Attribution-NonCommercial-NoDerivatives 4.0 International |
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openAccess |
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Universidade Federal de Goiás |
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Brasil |
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Universidade Federal de Goiás |
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