Avaliação físico-química, microbiológica e ecotoxicológica de efluentes oriundos de clínicas de oncologia do município de Goiânia

Detalhes bibliográficos
Ano de defesa: 2013
Autor(a) principal: Michelini, Lidiane Jorge lattes
Orientador(a): Kopp, Katia Alcione lattes
Banca de defesa: Kopp, Katia Alcione, Silva, Cláudio Carlos da, Siqueira, Eduardo Queija de, Brito, Núbia Natália de
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Federal de Goiás
Programa de Pós-Graduação: Programa de Pós-graduação em Engenharia do Meio Ambiente (EEC)
Departamento: Escola de Engenharia Civil - EEC (RG)
País: Brasil
Palavras-chave em Português:
Palavras-chave em Inglês:
Área do conhecimento CNPq:
Link de acesso: http://repositorio.bc.ufg.br/tede/handle/tede/3837
Resumo: The oncology institutions work with medicines of high capacity teratogenic, mutagenic and carcinogenic drugs. Antineoplastic agents are referred to as emerging contaminants, and the disturbing factor is that 10 to 50% of the quantity of chemotherapeutic inserted into the human body passes by the metabolism without changes. The human excretions and disposal incorrect of anticancer drugs are a concern due because the potential risk that characterizes this category of effluent in the environment. In Goiânia, wastewater from oncological institutions do not receive specific treatment, being carried by collector networks to Municipal Sewage Treatment Stations, which has no ability to withdraw these contaminants. Given the above, this study aims to characterize the effluent from two oncology clinics and compare them with a source of domestic wastewater through physical, chemical, microbiological and ecotoxicological properties. The physical, chemical and microbiological characteristics were chosen in order to consider the resolution CONAMA 430/2011, using the methodology proposed by Standard Methods for the Examination of Water and Wastewater, and the Environmental Protection Agency, and ecotoxicological analyzes were made on two test organisms, Ceriodaphnia dubia, second the Norm 13373/2010, for chronic and acute toxicity, and Allium cepa, second Fiskejö (1985) for cytotoxicity and genotoxity. As a result, it was found that the effluent from oncology clinics, although do not present differences in physical, chemical and microbiological tests in front of domestic effluent, showed high toxicity, with 100% mortality in Ceriodaphnia dubia, and aberrations of cytotoxic and genotoxic character in Allium cepa, at concentrations in the range of 6.25% in ecotoxicological tests. This shows the importance of this treatment before reaching the collecting public.
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spelling Kopp, Katia Alcionehttp://lattes.cnpq.br/1861626532483595Kopp, Katia AlcioneSilva, Cláudio Carlos daSiqueira, Eduardo Queija deBrito, Núbia Natália dehttp://lattes.cnpq.br/1325167041316491Michelini, Lidiane Jorge2014-12-29T15:39:44Z2013-07-09MICHELINI, Lidiane Jorge. Avaliação físico-química, microbiológica e ecotoxicológica de efluentes oriundos de clínicas de oncologia do município de Goiânia. 2013. 101 f. Dissertação (Mestrado em Engenharia do Meio Ambiente) - Universidade Federal de Goiás, Goiânia, 2014.http://repositorio.bc.ufg.br/tede/handle/tede/3837The oncology institutions work with medicines of high capacity teratogenic, mutagenic and carcinogenic drugs. Antineoplastic agents are referred to as emerging contaminants, and the disturbing factor is that 10 to 50% of the quantity of chemotherapeutic inserted into the human body passes by the metabolism without changes. The human excretions and disposal incorrect of anticancer drugs are a concern due because the potential risk that characterizes this category of effluent in the environment. In Goiânia, wastewater from oncological institutions do not receive specific treatment, being carried by collector networks to Municipal Sewage Treatment Stations, which has no ability to withdraw these contaminants. Given the above, this study aims to characterize the effluent from two oncology clinics and compare them with a source of domestic wastewater through physical, chemical, microbiological and ecotoxicological properties. The physical, chemical and microbiological characteristics were chosen in order to consider the resolution CONAMA 430/2011, using the methodology proposed by Standard Methods for the Examination of Water and Wastewater, and the Environmental Protection Agency, and ecotoxicological analyzes were made on two test organisms, Ceriodaphnia dubia, second the Norm 13373/2010, for chronic and acute toxicity, and Allium cepa, second Fiskejö (1985) for cytotoxicity and genotoxity. As a result, it was found that the effluent from oncology clinics, although do not present differences in physical, chemical and microbiological tests in front of domestic effluent, showed high toxicity, with 100% mortality in Ceriodaphnia dubia, and aberrations of cytotoxic and genotoxic character in Allium cepa, at concentrations in the range of 6.25% in ecotoxicological tests. This shows the importance of this treatment before reaching the collecting public.As instituições de oncologia trabalham com fármacos de alta capacidade teratogênica, mutagênica e carcinogênica. Os antineoplásicos são denominados como contaminantes emergentes, e o fator preocupante é que de 10 a 50% da quantidade de quimioterápicos inseridos no organismo passam pelo metabolismo humano sem sofrerem alteração. As excretas humanas e despejos incorretos de drogas quimioterápicas são motivos de preocupação devido ao risco potencial que essa categoria de efluente caracteriza para o meio ambiente. No município de Goiânia, as águas residuárias provenientes de instituições oncológicas não recebem tratamento específico, sendo transportadas por redes coletoras até Estações de Tratamento de Esgoto municipais, que não tem capacidade de retirada completa desses contaminantes. Diante do exposto, este trabalho objetiva caracterizar o efluente de duas clínicas de oncologia e compará-los com um efluente de origem doméstica por meio de análises físicas, químicas, microbiológicas e ecotoxicológicas. As análises físicas, químicas e microbiológicas foram escolhidas de forma a contemplar a resolução Conama 430/2011, utilizando a metodologia proposta pelo Standard Methods for the Examination of Water and Wastewater e pela Environmental Protection Agency e as análises ecotoxicológicas foram feitas em dois organismos testes, Ceriodaphnia dubia, para análise da toxicidade crônica e aguda, segundo a Norma NBR 13373/2010 e Allium cepa para ensaio de citotoxicidade e genotoxidade, segundo Fiskejö (1985). Como resultado, constatou-se que os efluentes das clínicas de oncologia, apesar de não apresentarem diferenças físicas, químicas e microbiológicas frente ao efluente doméstico, apresentaram alta toxicidade, com mortalidade de 100% em Ceriodaphnia dubia, e aberrações de caráter citotóxico e genotóxico em Allium cepa, em concentrações na faixa de 6,25% nas análises ecotoxicológicas. 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dc.title.por.fl_str_mv Avaliação físico-química, microbiológica e ecotoxicológica de efluentes oriundos de clínicas de oncologia do município de Goiânia
dc.title.alternative.eng.fl_str_mv Physico-chemical, microbiological and ecotoxicological evaluation of effluent coming from oncology clinics in the city of Goiânia
title Avaliação físico-química, microbiológica e ecotoxicológica de efluentes oriundos de clínicas de oncologia do município de Goiânia
spellingShingle Avaliação físico-química, microbiológica e ecotoxicológica de efluentes oriundos de clínicas de oncologia do município de Goiânia
Michelini, Lidiane Jorge
Efluente
Oncologia
Caracterização
Contaminantes emergentes
Effluent
Oncology
Characterization
Emerging contaminants
ENGENHARIA SANITARIA::SANEAMENTO AMBIENTAL
title_short Avaliação físico-química, microbiológica e ecotoxicológica de efluentes oriundos de clínicas de oncologia do município de Goiânia
title_full Avaliação físico-química, microbiológica e ecotoxicológica de efluentes oriundos de clínicas de oncologia do município de Goiânia
title_fullStr Avaliação físico-química, microbiológica e ecotoxicológica de efluentes oriundos de clínicas de oncologia do município de Goiânia
title_full_unstemmed Avaliação físico-química, microbiológica e ecotoxicológica de efluentes oriundos de clínicas de oncologia do município de Goiânia
title_sort Avaliação físico-química, microbiológica e ecotoxicológica de efluentes oriundos de clínicas de oncologia do município de Goiânia
author Michelini, Lidiane Jorge
author_facet Michelini, Lidiane Jorge
author_role author
dc.contributor.advisor1.fl_str_mv Kopp, Katia Alcione
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/1861626532483595
dc.contributor.referee1.fl_str_mv Kopp, Katia Alcione
dc.contributor.referee2.fl_str_mv Silva, Cláudio Carlos da
dc.contributor.referee3.fl_str_mv Siqueira, Eduardo Queija de
dc.contributor.referee4.fl_str_mv Brito, Núbia Natália de
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/1325167041316491
dc.contributor.author.fl_str_mv Michelini, Lidiane Jorge
contributor_str_mv Kopp, Katia Alcione
Kopp, Katia Alcione
Silva, Cláudio Carlos da
Siqueira, Eduardo Queija de
Brito, Núbia Natália de
dc.subject.por.fl_str_mv Efluente
Oncologia
Caracterização
Contaminantes emergentes
topic Efluente
Oncologia
Caracterização
Contaminantes emergentes
Effluent
Oncology
Characterization
Emerging contaminants
ENGENHARIA SANITARIA::SANEAMENTO AMBIENTAL
dc.subject.eng.fl_str_mv Effluent
Oncology
Characterization
Emerging contaminants
dc.subject.cnpq.fl_str_mv ENGENHARIA SANITARIA::SANEAMENTO AMBIENTAL
description The oncology institutions work with medicines of high capacity teratogenic, mutagenic and carcinogenic drugs. Antineoplastic agents are referred to as emerging contaminants, and the disturbing factor is that 10 to 50% of the quantity of chemotherapeutic inserted into the human body passes by the metabolism without changes. The human excretions and disposal incorrect of anticancer drugs are a concern due because the potential risk that characterizes this category of effluent in the environment. In Goiânia, wastewater from oncological institutions do not receive specific treatment, being carried by collector networks to Municipal Sewage Treatment Stations, which has no ability to withdraw these contaminants. Given the above, this study aims to characterize the effluent from two oncology clinics and compare them with a source of domestic wastewater through physical, chemical, microbiological and ecotoxicological properties. The physical, chemical and microbiological characteristics were chosen in order to consider the resolution CONAMA 430/2011, using the methodology proposed by Standard Methods for the Examination of Water and Wastewater, and the Environmental Protection Agency, and ecotoxicological analyzes were made on two test organisms, Ceriodaphnia dubia, second the Norm 13373/2010, for chronic and acute toxicity, and Allium cepa, second Fiskejö (1985) for cytotoxicity and genotoxity. As a result, it was found that the effluent from oncology clinics, although do not present differences in physical, chemical and microbiological tests in front of domestic effluent, showed high toxicity, with 100% mortality in Ceriodaphnia dubia, and aberrations of cytotoxic and genotoxic character in Allium cepa, at concentrations in the range of 6.25% in ecotoxicological tests. This shows the importance of this treatment before reaching the collecting public.
publishDate 2013
dc.date.issued.fl_str_mv 2013-07-09
dc.date.accessioned.fl_str_mv 2014-12-29T15:39:44Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
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dc.identifier.citation.fl_str_mv MICHELINI, Lidiane Jorge. Avaliação físico-química, microbiológica e ecotoxicológica de efluentes oriundos de clínicas de oncologia do município de Goiânia. 2013. 101 f. Dissertação (Mestrado em Engenharia do Meio Ambiente) - Universidade Federal de Goiás, Goiânia, 2014.
dc.identifier.uri.fl_str_mv http://repositorio.bc.ufg.br/tede/handle/tede/3837
identifier_str_mv MICHELINI, Lidiane Jorge. Avaliação físico-química, microbiológica e ecotoxicológica de efluentes oriundos de clínicas de oncologia do município de Goiânia. 2013. 101 f. Dissertação (Mestrado em Engenharia do Meio Ambiente) - Universidade Federal de Goiás, Goiânia, 2014.
url http://repositorio.bc.ufg.br/tede/handle/tede/3837
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dc.relation.confidence.fl_str_mv 600
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600
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dc.relation.cnpq.fl_str_mv 8018064043757118887
dc.relation.sponsorship.fl_str_mv 2075167498588264571
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dc.publisher.none.fl_str_mv Universidade Federal de Goiás
dc.publisher.program.fl_str_mv Programa de Pós-graduação em Engenharia do Meio Ambiente (EEC)
dc.publisher.initials.fl_str_mv UFG
dc.publisher.country.fl_str_mv Brasil
dc.publisher.department.fl_str_mv Escola de Engenharia Civil - EEC (RG)
publisher.none.fl_str_mv Universidade Federal de Goiás
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http://repositorio.bc.ufg.br/tede/bitstreams/7aa8e5d1-bbf3-4f63-9ed9-49592fc546ae/download
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repository.name.fl_str_mv Repositório Institucional da UFG - Universidade Federal de Goiás (UFG)
repository.mail.fl_str_mv tasesdissertacoes.bc@ufg.br
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