Avaliação físico-química, microbiológica e ecotoxicológica de efluentes oriundos de clínicas de oncologia do município de Goiânia
Ano de defesa: | 2013 |
---|---|
Autor(a) principal: | |
Orientador(a): | |
Banca de defesa: | , , , |
Tipo de documento: | Dissertação |
Tipo de acesso: | Acesso aberto |
Idioma: | por |
Instituição de defesa: |
Universidade Federal de Goiás
|
Programa de Pós-Graduação: |
Programa de Pós-graduação em Engenharia do Meio Ambiente (EEC)
|
Departamento: |
Escola de Engenharia Civil - EEC (RG)
|
País: |
Brasil
|
Palavras-chave em Português: | |
Palavras-chave em Inglês: | |
Área do conhecimento CNPq: | |
Link de acesso: | http://repositorio.bc.ufg.br/tede/handle/tede/3837 |
Resumo: | The oncology institutions work with medicines of high capacity teratogenic, mutagenic and carcinogenic drugs. Antineoplastic agents are referred to as emerging contaminants, and the disturbing factor is that 10 to 50% of the quantity of chemotherapeutic inserted into the human body passes by the metabolism without changes. The human excretions and disposal incorrect of anticancer drugs are a concern due because the potential risk that characterizes this category of effluent in the environment. In Goiânia, wastewater from oncological institutions do not receive specific treatment, being carried by collector networks to Municipal Sewage Treatment Stations, which has no ability to withdraw these contaminants. Given the above, this study aims to characterize the effluent from two oncology clinics and compare them with a source of domestic wastewater through physical, chemical, microbiological and ecotoxicological properties. The physical, chemical and microbiological characteristics were chosen in order to consider the resolution CONAMA 430/2011, using the methodology proposed by Standard Methods for the Examination of Water and Wastewater, and the Environmental Protection Agency, and ecotoxicological analyzes were made on two test organisms, Ceriodaphnia dubia, second the Norm 13373/2010, for chronic and acute toxicity, and Allium cepa, second Fiskejö (1985) for cytotoxicity and genotoxity. As a result, it was found that the effluent from oncology clinics, although do not present differences in physical, chemical and microbiological tests in front of domestic effluent, showed high toxicity, with 100% mortality in Ceriodaphnia dubia, and aberrations of cytotoxic and genotoxic character in Allium cepa, at concentrations in the range of 6.25% in ecotoxicological tests. This shows the importance of this treatment before reaching the collecting public. |
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Kopp, Katia Alcionehttp://lattes.cnpq.br/1861626532483595Kopp, Katia AlcioneSilva, Cláudio Carlos daSiqueira, Eduardo Queija deBrito, Núbia Natália dehttp://lattes.cnpq.br/1325167041316491Michelini, Lidiane Jorge2014-12-29T15:39:44Z2013-07-09MICHELINI, Lidiane Jorge. Avaliação físico-química, microbiológica e ecotoxicológica de efluentes oriundos de clínicas de oncologia do município de Goiânia. 2013. 101 f. Dissertação (Mestrado em Engenharia do Meio Ambiente) - Universidade Federal de Goiás, Goiânia, 2014.http://repositorio.bc.ufg.br/tede/handle/tede/3837The oncology institutions work with medicines of high capacity teratogenic, mutagenic and carcinogenic drugs. Antineoplastic agents are referred to as emerging contaminants, and the disturbing factor is that 10 to 50% of the quantity of chemotherapeutic inserted into the human body passes by the metabolism without changes. The human excretions and disposal incorrect of anticancer drugs are a concern due because the potential risk that characterizes this category of effluent in the environment. In Goiânia, wastewater from oncological institutions do not receive specific treatment, being carried by collector networks to Municipal Sewage Treatment Stations, which has no ability to withdraw these contaminants. Given the above, this study aims to characterize the effluent from two oncology clinics and compare them with a source of domestic wastewater through physical, chemical, microbiological and ecotoxicological properties. The physical, chemical and microbiological characteristics were chosen in order to consider the resolution CONAMA 430/2011, using the methodology proposed by Standard Methods for the Examination of Water and Wastewater, and the Environmental Protection Agency, and ecotoxicological analyzes were made on two test organisms, Ceriodaphnia dubia, second the Norm 13373/2010, for chronic and acute toxicity, and Allium cepa, second Fiskejö (1985) for cytotoxicity and genotoxity. As a result, it was found that the effluent from oncology clinics, although do not present differences in physical, chemical and microbiological tests in front of domestic effluent, showed high toxicity, with 100% mortality in Ceriodaphnia dubia, and aberrations of cytotoxic and genotoxic character in Allium cepa, at concentrations in the range of 6.25% in ecotoxicological tests. This shows the importance of this treatment before reaching the collecting public.As instituições de oncologia trabalham com fármacos de alta capacidade teratogênica, mutagênica e carcinogênica. Os antineoplásicos são denominados como contaminantes emergentes, e o fator preocupante é que de 10 a 50% da quantidade de quimioterápicos inseridos no organismo passam pelo metabolismo humano sem sofrerem alteração. As excretas humanas e despejos incorretos de drogas quimioterápicas são motivos de preocupação devido ao risco potencial que essa categoria de efluente caracteriza para o meio ambiente. No município de Goiânia, as águas residuárias provenientes de instituições oncológicas não recebem tratamento específico, sendo transportadas por redes coletoras até Estações de Tratamento de Esgoto municipais, que não tem capacidade de retirada completa desses contaminantes. Diante do exposto, este trabalho objetiva caracterizar o efluente de duas clínicas de oncologia e compará-los com um efluente de origem doméstica por meio de análises físicas, químicas, microbiológicas e ecotoxicológicas. As análises físicas, químicas e microbiológicas foram escolhidas de forma a contemplar a resolução Conama 430/2011, utilizando a metodologia proposta pelo Standard Methods for the Examination of Water and Wastewater e pela Environmental Protection Agency e as análises ecotoxicológicas foram feitas em dois organismos testes, Ceriodaphnia dubia, para análise da toxicidade crônica e aguda, segundo a Norma NBR 13373/2010 e Allium cepa para ensaio de citotoxicidade e genotoxidade, segundo Fiskejö (1985). Como resultado, constatou-se que os efluentes das clínicas de oncologia, apesar de não apresentarem diferenças físicas, químicas e microbiológicas frente ao efluente doméstico, apresentaram alta toxicidade, com mortalidade de 100% em Ceriodaphnia dubia, e aberrações de caráter citotóxico e genotóxico em Allium cepa, em concentrações na faixa de 6,25% nas análises ecotoxicológicas. O que denota a importância do tratamento deste antes de atingir a rede pública coletora.Submitted by Erika Demachki (erikademachki@gmail.com) on 2014-12-29T15:33:45Z No. of bitstreams: 2 license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5) Dissertação - Lidiane Jorge Michelini - 2013.pdf: 2488951 bytes, checksum: 5602f2e03b8690a88ef19a4e7dab60e4 (MD5)Approved for entry into archive by Erika Demachki (erikademachki@gmail.com) on 2014-12-29T15:39:44Z (GMT) No. of bitstreams: 2 license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5) Dissertação - Lidiane Jorge Michelini - 2013.pdf: 2488951 bytes, checksum: 5602f2e03b8690a88ef19a4e7dab60e4 (MD5)Made available in DSpace on 2014-12-29T15:39:44Z (GMT). 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dc.title.por.fl_str_mv |
Avaliação físico-química, microbiológica e ecotoxicológica de efluentes oriundos de clínicas de oncologia do município de Goiânia |
dc.title.alternative.eng.fl_str_mv |
Physico-chemical, microbiological and ecotoxicological evaluation of effluent coming from oncology clinics in the city of Goiânia |
title |
Avaliação físico-química, microbiológica e ecotoxicológica de efluentes oriundos de clínicas de oncologia do município de Goiânia |
spellingShingle |
Avaliação físico-química, microbiológica e ecotoxicológica de efluentes oriundos de clínicas de oncologia do município de Goiânia Michelini, Lidiane Jorge Efluente Oncologia Caracterização Contaminantes emergentes Effluent Oncology Characterization Emerging contaminants ENGENHARIA SANITARIA::SANEAMENTO AMBIENTAL |
title_short |
Avaliação físico-química, microbiológica e ecotoxicológica de efluentes oriundos de clínicas de oncologia do município de Goiânia |
title_full |
Avaliação físico-química, microbiológica e ecotoxicológica de efluentes oriundos de clínicas de oncologia do município de Goiânia |
title_fullStr |
Avaliação físico-química, microbiológica e ecotoxicológica de efluentes oriundos de clínicas de oncologia do município de Goiânia |
title_full_unstemmed |
Avaliação físico-química, microbiológica e ecotoxicológica de efluentes oriundos de clínicas de oncologia do município de Goiânia |
title_sort |
Avaliação físico-química, microbiológica e ecotoxicológica de efluentes oriundos de clínicas de oncologia do município de Goiânia |
author |
Michelini, Lidiane Jorge |
author_facet |
Michelini, Lidiane Jorge |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Kopp, Katia Alcione |
dc.contributor.advisor1Lattes.fl_str_mv |
http://lattes.cnpq.br/1861626532483595 |
dc.contributor.referee1.fl_str_mv |
Kopp, Katia Alcione |
dc.contributor.referee2.fl_str_mv |
Silva, Cláudio Carlos da |
dc.contributor.referee3.fl_str_mv |
Siqueira, Eduardo Queija de |
dc.contributor.referee4.fl_str_mv |
Brito, Núbia Natália de |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/1325167041316491 |
dc.contributor.author.fl_str_mv |
Michelini, Lidiane Jorge |
contributor_str_mv |
Kopp, Katia Alcione Kopp, Katia Alcione Silva, Cláudio Carlos da Siqueira, Eduardo Queija de Brito, Núbia Natália de |
dc.subject.por.fl_str_mv |
Efluente Oncologia Caracterização Contaminantes emergentes |
topic |
Efluente Oncologia Caracterização Contaminantes emergentes Effluent Oncology Characterization Emerging contaminants ENGENHARIA SANITARIA::SANEAMENTO AMBIENTAL |
dc.subject.eng.fl_str_mv |
Effluent Oncology Characterization Emerging contaminants |
dc.subject.cnpq.fl_str_mv |
ENGENHARIA SANITARIA::SANEAMENTO AMBIENTAL |
description |
The oncology institutions work with medicines of high capacity teratogenic, mutagenic and carcinogenic drugs. Antineoplastic agents are referred to as emerging contaminants, and the disturbing factor is that 10 to 50% of the quantity of chemotherapeutic inserted into the human body passes by the metabolism without changes. The human excretions and disposal incorrect of anticancer drugs are a concern due because the potential risk that characterizes this category of effluent in the environment. In Goiânia, wastewater from oncological institutions do not receive specific treatment, being carried by collector networks to Municipal Sewage Treatment Stations, which has no ability to withdraw these contaminants. Given the above, this study aims to characterize the effluent from two oncology clinics and compare them with a source of domestic wastewater through physical, chemical, microbiological and ecotoxicological properties. The physical, chemical and microbiological characteristics were chosen in order to consider the resolution CONAMA 430/2011, using the methodology proposed by Standard Methods for the Examination of Water and Wastewater, and the Environmental Protection Agency, and ecotoxicological analyzes were made on two test organisms, Ceriodaphnia dubia, second the Norm 13373/2010, for chronic and acute toxicity, and Allium cepa, second Fiskejö (1985) for cytotoxicity and genotoxity. As a result, it was found that the effluent from oncology clinics, although do not present differences in physical, chemical and microbiological tests in front of domestic effluent, showed high toxicity, with 100% mortality in Ceriodaphnia dubia, and aberrations of cytotoxic and genotoxic character in Allium cepa, at concentrations in the range of 6.25% in ecotoxicological tests. This shows the importance of this treatment before reaching the collecting public. |
publishDate |
2013 |
dc.date.issued.fl_str_mv |
2013-07-09 |
dc.date.accessioned.fl_str_mv |
2014-12-29T15:39:44Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
format |
masterThesis |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
MICHELINI, Lidiane Jorge. Avaliação físico-química, microbiológica e ecotoxicológica de efluentes oriundos de clínicas de oncologia do município de Goiânia. 2013. 101 f. Dissertação (Mestrado em Engenharia do Meio Ambiente) - Universidade Federal de Goiás, Goiânia, 2014. |
dc.identifier.uri.fl_str_mv |
http://repositorio.bc.ufg.br/tede/handle/tede/3837 |
identifier_str_mv |
MICHELINI, Lidiane Jorge. Avaliação físico-química, microbiológica e ecotoxicológica de efluentes oriundos de clínicas de oncologia do município de Goiânia. 2013. 101 f. Dissertação (Mestrado em Engenharia do Meio Ambiente) - Universidade Federal de Goiás, Goiânia, 2014. |
url |
http://repositorio.bc.ufg.br/tede/handle/tede/3837 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.program.fl_str_mv |
1009702091972874847 |
dc.relation.confidence.fl_str_mv |
600 600 600 600 |
dc.relation.department.fl_str_mv |
724087251626315585 |
dc.relation.cnpq.fl_str_mv |
8018064043757118887 |
dc.relation.sponsorship.fl_str_mv |
2075167498588264571 |
dc.rights.driver.fl_str_mv |
http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
http://creativecommons.org/licenses/by-nc-nd/4.0/ |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Federal de Goiás |
dc.publisher.program.fl_str_mv |
Programa de Pós-graduação em Engenharia do Meio Ambiente (EEC) |
dc.publisher.initials.fl_str_mv |
UFG |
dc.publisher.country.fl_str_mv |
Brasil |
dc.publisher.department.fl_str_mv |
Escola de Engenharia Civil - EEC (RG) |
publisher.none.fl_str_mv |
Universidade Federal de Goiás |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UFG instname:Universidade Federal de Goiás (UFG) instacron:UFG |
instname_str |
Universidade Federal de Goiás (UFG) |
instacron_str |
UFG |
institution |
UFG |
reponame_str |
Repositório Institucional da UFG |
collection |
Repositório Institucional da UFG |
bitstream.url.fl_str_mv |
http://repositorio.bc.ufg.br/tede/bitstreams/3323198a-2b4c-46a2-8dd9-4fed8dc06d30/download http://repositorio.bc.ufg.br/tede/bitstreams/a0656259-3b4c-465b-b48a-fda6362353ef/download http://repositorio.bc.ufg.br/tede/bitstreams/4459b9e9-cf59-465b-86de-b69da6f51de3/download http://repositorio.bc.ufg.br/tede/bitstreams/72c26b3c-7c70-47d6-b935-dc7294ceca0f/download http://repositorio.bc.ufg.br/tede/bitstreams/76709b97-0746-4a84-8b80-d886c563ad91/download http://repositorio.bc.ufg.br/tede/bitstreams/5032da54-8744-40de-8536-ddbc30354873/download http://repositorio.bc.ufg.br/tede/bitstreams/7aa8e5d1-bbf3-4f63-9ed9-49592fc546ae/download |
bitstream.checksum.fl_str_mv |
5602f2e03b8690a88ef19a4e7dab60e4 3fcea78dc0f81277f8f1b0df880f26b2 c10b38c5fbbddeddeea5e672850128f0 bd3efa91386c1718a7f26a329fdcb468 4afdbb8c545fd630ea7db775da747b2f 29b9d5e95be03707f9d4a2e110421c11 9da0b6dfac957114c6a7714714b86306 |
bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 MD5 MD5 MD5 MD5 |
repository.name.fl_str_mv |
Repositório Institucional da UFG - Universidade Federal de Goiás (UFG) |
repository.mail.fl_str_mv |
tasesdissertacoes.bc@ufg.br |
_version_ |
1798045041937088512 |