CARACTERIZAÇÃO DE EXTRATOS DA GEOPRÓPOLIS DE Melipona fasciculata Smith de biomas maranhenses.

Detalhes bibliográficos
Ano de defesa: 2017
Autor(a) principal: ROCHA, Aliny Oliveira lattes
Orientador(a): AMARAL, Flavia Maria Mendonça do lattes
Banca de defesa: AMARAL, Flavia Maria Mendonça do lattes, MORAES, Denise Fernandes Coutinho lattes, CARTAGENES, Maria do Socorro de Sousa lattes, SOUZA, Neuton da Silva lattes
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Federal do Maranhão
Programa de Pós-Graduação: PROGRAMA DE PÓS-GRADUAÇÃO EM SAÚDE E AMBIENTE/CCBS
Departamento: DEPARTAMENTO DE FARMÁCIA/CCBS
País: Brasil
Palavras-chave em Português:
Palavras-chave em Inglês:
Área do conhecimento CNPq:
Link de acesso: https://riufma.ufma.br/handle/tede/2745
Resumo: Melipona fasciculata Smith, a stingless social bee, is cultivated in the state of Maranhão for honey production, but also produces wax and geoprópolis besides accumulating pollen (source of protein, lipids and vitamins) and nectar (carbohydrate source). Representing source of income for several rural families. Geopropolis is formed by collecting resinous plant material, mixed with wax and salivary secretions and added soil. Antibacterial, anti-inflammatory, antioxidant, antitumoral and leishmanicidal actions were reported for Melipona fasciculata geoprópolis; Being demonstrated the presence of phenolic acids, flavonoids, triterpenes and tannins. Given the representativeness of the geopropolis and the need to add value, this work aimed to characterize the geoprópolis of Melipona fasciculata from different biomes of the state of Maranhão, aiming to contribute with parameters of product quality. The geopropolis samples were collected in 04 (four) municipalities located in 03 (three) biomes (Transition Zone between Amazonia-Cerrado-Caatinga-Costeiro, Amazônia and Cerrado Maranhense); submitted to the evaluation of the chemical composition (spectrophotometry and absorption in the ultraviolet / visible region, high performance liquid chromatography with ultraviolet / visible detector, high efficiency liquid chromatography with diode arrangement detector coupled to mass spectrometry with Ionization by electrospray) and antioxidant activity (DPPH, ABTS and FRAP). The results show that the samples of the Transition Zone between Amazonia-Cerrado-Caatinga-Costeiro Maranhense show antioxidant activity, being the sample with more characteristics of Cerrado of the municipality of Belágua with better antioxidant content, probably given to the polyphenolic compounds evidenced in this sample; Showing a good correlation of the total polyphenol contents with the DPPH and ABTS methods. Among the polyphenols, hydrolysable tannins were identified in the extract of the municipality of Belágua. The geopropolis extract from the municipality of Belágua, transition zone, presented more significant results. The results obtained allow to add value of the geopropolis of, as potential antioxidant products. Melipona fasciculata.
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spelling 2019-06-26T12:19:27Z2026-09-19T13:19:59Z2017-02-22ROCHA, Aliny Oliveira.Caracterização de extratos da geoprópolis de Melipona fasciculata Smith de biomas maranhenses.. 2017. 66 folhas. Dissertação( Programa de Pós-Graduação em Saúde e Ambiente/CCBS) - Universidade Federal do Maranhão, São Luis.https://riufma.ufma.br/handle/tede/2745Melipona fasciculata Smith, a stingless social bee, is cultivated in the state of Maranhão for honey production, but also produces wax and geoprópolis besides accumulating pollen (source of protein, lipids and vitamins) and nectar (carbohydrate source). Representing source of income for several rural families. Geopropolis is formed by collecting resinous plant material, mixed with wax and salivary secretions and added soil. Antibacterial, anti-inflammatory, antioxidant, antitumoral and leishmanicidal actions were reported for Melipona fasciculata geoprópolis; Being demonstrated the presence of phenolic acids, flavonoids, triterpenes and tannins. Given the representativeness of the geopropolis and the need to add value, this work aimed to characterize the geoprópolis of Melipona fasciculata from different biomes of the state of Maranhão, aiming to contribute with parameters of product quality. The geopropolis samples were collected in 04 (four) municipalities located in 03 (three) biomes (Transition Zone between Amazonia-Cerrado-Caatinga-Costeiro, Amazônia and Cerrado Maranhense); submitted to the evaluation of the chemical composition (spectrophotometry and absorption in the ultraviolet / visible region, high performance liquid chromatography with ultraviolet / visible detector, high efficiency liquid chromatography with diode arrangement detector coupled to mass spectrometry with Ionization by electrospray) and antioxidant activity (DPPH, ABTS and FRAP). The results show that the samples of the Transition Zone between Amazonia-Cerrado-Caatinga-Costeiro Maranhense show antioxidant activity, being the sample with more characteristics of Cerrado of the municipality of Belágua with better antioxidant content, probably given to the polyphenolic compounds evidenced in this sample; Showing a good correlation of the total polyphenol contents with the DPPH and ABTS methods. Among the polyphenols, hydrolysable tannins were identified in the extract of the municipality of Belágua. The geopropolis extract from the municipality of Belágua, transition zone, presented more significant results. The results obtained allow to add value of the geopropolis of, as potential antioxidant products. Melipona fasciculata.Melipona fasciculata Smith (tiúba), abelha social sem ferrão, é cultivada no estado do Maranhão para produção de mel, mas produz também cera e geoprópolis além de acumularem pólen (fonte de proteína, lipídios e vitaminas) e néctar (fonte de carboidrato), representando fonte de renda para várias famílias rurais. Geoprópolis é formada através da coleta de material resinoso de plantas, misturado com cera e secreções salivares e adicionada terra. Ações antibacterianas, antiinflamatória, antioxidante, antitumoral e leishmanicida foram referidas para geoprópolis de Melipona fasciculata; sendo demonstrado a presença de ácidos fenólicos, flavonoides, triterpenos e taninos. Dada à representatividade da geoprópolis e necessidade de agregar valor, este trabalho teve como objetivo realizar ensaios de caracterização com geoprópolis de Melipona fasciculata de diferentes biomas do estado do Maranhão, visando contribuir com parâmetros de qualidade do produto. As amostras de geoprópolis foram coletadas em (quatro) municípios localizados em 03 (três) biomas (Zona de Transição entre Amazônia-Cerrado-Caatinga-Costeiro, Amazônia e Cerrado Maranhense); submetidas à avaliação da composição química (espectrofotometria e absorção na região do Ultravioleta/Visível, cromatografia líquida de alta eficiência com detector de Ultravioleta/Visível, cromatografia líquida de alta eficiência com detector de arranjo de diodo acoplado a espectrômetria de massas com ionização por eletrospray) e atividade antioxidante (DPPH, ABTS e FRAP). Os resultados demonstram que as amostras da Zona de Transição entre Amazônia-Cerrado-Caatinga-Costeiro Maranhense apresentam atividade antioxidante sendo a amostra com mais características de Cerrado do município de Belágua com melhor teor antioxidante, provavelmente dada aos compostos polifenólicos evidenciados nessa amostra; sendo demonstrada boa correlação dos teores de polifenóis totais com os métodos DPPH e ABTS. Dentre os polifenóis foram identificados taninos hidrolisáveis no extrato do município de Belágua. O extrato de geoprópolis oriundo do município de Belágua, zona de transição, apresentou resultados mais significativos. Os resultados obtidos permitem agregar valor da geoprópolis de Melipona fasciculata, como potenciais produtos antioxidantes.application/pdfporUniversidade Federal do MaranhãoPROGRAMA DE PÓS-GRADUAÇÃO EM SAÚDE E AMBIENTE/CCBSUFMABrasilDEPARTAMENTO DE FARMÁCIA/CCBSabelha sem ferrão; atividade antioxidante; taninos hidrolisáveisstingless bee; antioxidant activity; hydrolysable tanninsEcologia Aplicada.CARACTERIZAÇÃO DE EXTRATOS DA GEOPRÓPOLIS DE Melipona fasciculata Smith de biomas maranhenses.CHARACTERIZATION OF GEOPROPOLIS EXTRACTS FROM Melipona fasciculata Smith of Maranhenses bioms.info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisAMARAL, Flavia Maria Mendonça dohttp://lattes.cnpq.br/9334507801916334AMARAL, Flavia Maria Mendonça dohttp://lattes.cnpq.br/9334507801916334MORAES, Denise Fernandes Coutinhohttp://lattes.cnpq.br/7346399893912346CARTAGENES, Maria do Socorro de Sousahttp://lattes.cnpq.br/3013333572719007SOUZA, Neuton da Silvahttp://lattes.cnpq.br/6314817497876535http://lattes.cnpq.br/3539521317503070ROCHA, Aliny Oliveirainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMAinstname:Universidade Federal do Maranhão (UFMA)instacron:UFMALICENSElicense.txttext/plain; charset=utf-82393https://riufma.ufma.br/bitstreams/c7a85988-01e6-43e4-84f7-c4f615c30289/downloadb8cec2d454e25b568428ee63784602fdMD55falseAnonymousREADORIGINALAliny Oliveira R..pdfDissertação de Mestrado.application/pdf1463870https://riufma.ufma.br/bitstreams/ac192d80-1def-42ef-91ba-4fb0a5d5f585/download0e7f55261e417d9b9ca8194cd64cfa38MD52trueAnonymousREADTEXTAliny Oliveira R..pdf.txtWritten by FormatFilter org.dspace.app.mediafilter.TikaTextExtractionFilter on 2026-09-24T01:36:15Z (GMT).Extracted texttext/plain102725https://riufma.ufma.br/bitstreams/b64d226a-53ba-400b-8270-1bddbbd65af8/download34bbc598f48267ea04c214bd8cd44fb3MD53falseAnonymousREADTHUMBNAILAliny Oliveira R..pdf.jpgWritten by FormatFilter org.dspace.app.mediafilter.PDFBoxThumbnail on 2026-09-24T01:36:15Z (GMT).Generated Thumbnailimage/jpeg2578https://riufma.ufma.br/bitstreams/c9b580e6-aa81-493b-bdc4-8245d74bcdc2/download2bf802fe3d5353c0f92d58e6b75d610fMD54falseAnonymousREADtede/27452026-10-16T22:34:47.138035Zopen.accessoai:riufma.ufma.br:tede/2745https://riufma.ufma.brRepositório InstitucionalPUBhttp://repositorio.ufma.br:8080/oai/requestrepositorio@ufma.bropendoar:2026-10-16T22:34:47Repositório Institucional da UFMA - Universidade Federal do Maranhão (UFMA)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
dc.title.por.fl_str_mv CARACTERIZAÇÃO DE EXTRATOS DA GEOPRÓPOLIS DE Melipona fasciculata Smith de biomas maranhenses.
dc.title.alternative.eng.fl_str_mv CHARACTERIZATION OF GEOPROPOLIS EXTRACTS FROM Melipona fasciculata Smith of Maranhenses bioms.
title CARACTERIZAÇÃO DE EXTRATOS DA GEOPRÓPOLIS DE Melipona fasciculata Smith de biomas maranhenses.
spellingShingle CARACTERIZAÇÃO DE EXTRATOS DA GEOPRÓPOLIS DE Melipona fasciculata Smith de biomas maranhenses.
ROCHA, Aliny Oliveira
abelha sem ferrão; atividade antioxidante; taninos hidrolisáveis
stingless bee; antioxidant activity; hydrolysable tannins
Ecologia Aplicada.
title_short CARACTERIZAÇÃO DE EXTRATOS DA GEOPRÓPOLIS DE Melipona fasciculata Smith de biomas maranhenses.
title_full CARACTERIZAÇÃO DE EXTRATOS DA GEOPRÓPOLIS DE Melipona fasciculata Smith de biomas maranhenses.
title_fullStr CARACTERIZAÇÃO DE EXTRATOS DA GEOPRÓPOLIS DE Melipona fasciculata Smith de biomas maranhenses.
title_full_unstemmed CARACTERIZAÇÃO DE EXTRATOS DA GEOPRÓPOLIS DE Melipona fasciculata Smith de biomas maranhenses.
title_sort CARACTERIZAÇÃO DE EXTRATOS DA GEOPRÓPOLIS DE Melipona fasciculata Smith de biomas maranhenses.
author ROCHA, Aliny Oliveira
author_facet ROCHA, Aliny Oliveira
author_role author
dc.contributor.advisor1.fl_str_mv AMARAL, Flavia Maria Mendonça do
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/9334507801916334
dc.contributor.referee1.fl_str_mv AMARAL, Flavia Maria Mendonça do
dc.contributor.referee1Lattes.fl_str_mv http://lattes.cnpq.br/9334507801916334
dc.contributor.referee2.fl_str_mv MORAES, Denise Fernandes Coutinho
dc.contributor.referee2Lattes.fl_str_mv http://lattes.cnpq.br/7346399893912346
dc.contributor.referee3.fl_str_mv CARTAGENES, Maria do Socorro de Sousa
dc.contributor.referee3Lattes.fl_str_mv http://lattes.cnpq.br/3013333572719007
dc.contributor.referee4.fl_str_mv SOUZA, Neuton da Silva
dc.contributor.referee4Lattes.fl_str_mv http://lattes.cnpq.br/6314817497876535
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/3539521317503070
dc.contributor.author.fl_str_mv ROCHA, Aliny Oliveira
contributor_str_mv AMARAL, Flavia Maria Mendonça do
AMARAL, Flavia Maria Mendonça do
MORAES, Denise Fernandes Coutinho
CARTAGENES, Maria do Socorro de Sousa
SOUZA, Neuton da Silva
dc.subject.por.fl_str_mv abelha sem ferrão; atividade antioxidante; taninos hidrolisáveis
topic abelha sem ferrão; atividade antioxidante; taninos hidrolisáveis
stingless bee; antioxidant activity; hydrolysable tannins
Ecologia Aplicada.
dc.subject.eng.fl_str_mv stingless bee; antioxidant activity; hydrolysable tannins
dc.subject.cnpq.fl_str_mv Ecologia Aplicada.
description Melipona fasciculata Smith, a stingless social bee, is cultivated in the state of Maranhão for honey production, but also produces wax and geoprópolis besides accumulating pollen (source of protein, lipids and vitamins) and nectar (carbohydrate source). Representing source of income for several rural families. Geopropolis is formed by collecting resinous plant material, mixed with wax and salivary secretions and added soil. Antibacterial, anti-inflammatory, antioxidant, antitumoral and leishmanicidal actions were reported for Melipona fasciculata geoprópolis; Being demonstrated the presence of phenolic acids, flavonoids, triterpenes and tannins. Given the representativeness of the geopropolis and the need to add value, this work aimed to characterize the geoprópolis of Melipona fasciculata from different biomes of the state of Maranhão, aiming to contribute with parameters of product quality. The geopropolis samples were collected in 04 (four) municipalities located in 03 (three) biomes (Transition Zone between Amazonia-Cerrado-Caatinga-Costeiro, Amazônia and Cerrado Maranhense); submitted to the evaluation of the chemical composition (spectrophotometry and absorption in the ultraviolet / visible region, high performance liquid chromatography with ultraviolet / visible detector, high efficiency liquid chromatography with diode arrangement detector coupled to mass spectrometry with Ionization by electrospray) and antioxidant activity (DPPH, ABTS and FRAP). The results show that the samples of the Transition Zone between Amazonia-Cerrado-Caatinga-Costeiro Maranhense show antioxidant activity, being the sample with more characteristics of Cerrado of the municipality of Belágua with better antioxidant content, probably given to the polyphenolic compounds evidenced in this sample; Showing a good correlation of the total polyphenol contents with the DPPH and ABTS methods. Among the polyphenols, hydrolysable tannins were identified in the extract of the municipality of Belágua. The geopropolis extract from the municipality of Belágua, transition zone, presented more significant results. The results obtained allow to add value of the geopropolis of, as potential antioxidant products. Melipona fasciculata.
publishDate 2017
dc.date.issued.fl_str_mv 2017-02-22
dc.date.accessioned.fl_str_mv 2019-06-26T12:19:27Z
2026-09-19T13:19:59Z
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dc.identifier.citation.fl_str_mv ROCHA, Aliny Oliveira.Caracterização de extratos da geoprópolis de Melipona fasciculata Smith de biomas maranhenses.. 2017. 66 folhas. Dissertação( Programa de Pós-Graduação em Saúde e Ambiente/CCBS) - Universidade Federal do Maranhão, São Luis.
dc.identifier.uri.fl_str_mv https://riufma.ufma.br/handle/tede/2745
identifier_str_mv ROCHA, Aliny Oliveira.Caracterização de extratos da geoprópolis de Melipona fasciculata Smith de biomas maranhenses.. 2017. 66 folhas. Dissertação( Programa de Pós-Graduação em Saúde e Ambiente/CCBS) - Universidade Federal do Maranhão, São Luis.
url https://riufma.ufma.br/handle/tede/2745
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dc.publisher.none.fl_str_mv Universidade Federal do Maranhão
dc.publisher.program.fl_str_mv PROGRAMA DE PÓS-GRADUAÇÃO EM SAÚDE E AMBIENTE/CCBS
dc.publisher.initials.fl_str_mv UFMA
dc.publisher.country.fl_str_mv Brasil
dc.publisher.department.fl_str_mv DEPARTAMENTO DE FARMÁCIA/CCBS
publisher.none.fl_str_mv Universidade Federal do Maranhão
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