FENÓTIPO DA CINTURA HIPERTRIGLICERIDÊMICA E LESÃO RENAL EM PACIENTES HIPERTENSOS ASSISTIDOS EM UM CENTRO DE PREVENÇÃO DE DOENÇA RENAL.

• Ano de defesa: 2019
• Autor(a) principal: MEDEIROS, Thaynara Helena Ribeiro e Silva
• Orientador(a): MONTEIRO, Sally Cristina Moutinho
• Banca de defesa: MONTEIRO, Sally Cristina Moutinho , FONTENELE, Andrea Melo Martins , SARDINHA, Ana Helia de Lima , CHAGAS, Deysianne Costa das
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal do Maranhão
• Programa de Pós-Graduação: PROGRAMA DE PÓS-GRADUAÇÃO EM SAÚDE DO ADULTO E DA CRIANÇA/CCBS
• Departamento: DEPARTAMENTO DE FARMÁCIA/CCBS
• País: Brasil
• Palavras-chave em Português: Cintura Hipertrigliceridêmica; Insuficiência Renal Crônica; Obesidade abdominal; Hipertensão
• Palavras-chave em Inglês: Hypertriglyceridemic waist; Chronic Renal Failure; Abdominal Obesity; Hypertension
• Área do conhecimento CNPq: Nefrologia
• Link de acesso: https://tedebc.ufma.br/jspui/handle/tede/2980

Chronic kidney disease (CKD) has become an important public health problem in the world population due to the increase in its prevalence and its significant association with other important chronic diseases. This study aims to verify the association between the hypertriglyceridemic waist phenotype (FCH) and the estimated glomerular filtration rate (eTFG) in a population of hypertensive patients attended at a center for the prevention of renal diseases in the city of São Luís / MA. Methodology: This is a cross-sectional, retrospective and quantitative study conducted at the Center for the Prevention of Renal Disease at the Presidente Dutra University Hospital - UFMA. Socio-demographic data, clinical conditions and laboratory tests were collected from the medical charts between the years 2013-2017. The data obtained were analyzed from the SPSS 21.0® statistical program using Student's t test to relate the serum and anthropometric variables to changes in the Rhythm of Glomerular Filtration and Shapiro-Wilk test for normality. Differences were considered significant when p value <0.05. RESULTS: 146 medical records were selected, 84.2% had FCH and 15.8% did not present the phenotype. The eRFG presented a mean of 91.4 ± 42.6 mL / min by 1.73 m² in the group without FCH and in the group with FCH the mean of 69.3 ± 23.9 mL / min by 1.73 m², with significant association (p <0.0047). All the anthropometric variables investigated were associated with the presence of the hypertriglyceridemic waist phenotype. In the present study, the hypertriglyceridemic waist phenotype was associated with an estimate of the glomerular filtration rate in hypertensive individuals. The hypertriglyceridemic waist phenotype (HCF) was also associated with increased anthropometric indexes such as CER, HF and IAP as well as increased biochemical variables, such as fasting blood glucose, TyG index, LAP index, and IAC.