Perfil sorológico e avaliação pós-vacinal de lobos-guarás Chrysocyon brachyurus (Illiger, 1811) para os vírus da Cinomose e Parvovirose caninas

• Ano de defesa: 1998
• Autor(a) principal: Otavio Borges Maia
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de Minas Gerais
• Palavras-chave em Português: Veterinária; Parvovirose Vacinação; Sorodiagnostico; Cinomose Vacinação
• Link de acesso: https://hdl.handle.net/1843/BUOS-8PJFVF

Serological survey of captive maned wolves Crysocyon brachyurus (Illiger, 1811) for canine distemper virus (CDV) and canine parvovirus (CPV) and post-vaccination evaluation The maned wolf is the largest South American canid and one of the most typical species from Brazilian savannah, included in the Offcial List of the Threatened of Extinction Brazilian Fauna. According to analysis of the International Studbook for the Maned Wolf, CDV and CPV are the most frequent infectious diseases in this species in the 1980-94 period, both being responsible for 10% of death in captivity. The objective of this study was to establish the serological status of maned wolves prior to vaccination and post-vaccination evaluation with modified-live vaccine against CDV and CPV, developed for domestic dogs. Samples of serum of 55 specimens of maned wolves 38 adults and 17 pups - coming from the seven Brazilian Zoos and of the nature, were used for serological profile verification. For the post-vacinal evaluation, 361 samples were tsted for CDV, and 353 samples for CPV, obtained from 47 specimens of different ages 36 adults and 13 pups maintained by six zoos. The adult animals and pups (younger than six month), were vaccinated with two and three doses, respectively, of mixed vaccine produced for domatic dogs (EURICAN®, Merial), at intervals of 30 days. Blood sarnples were collected in the day of the vaccinations and at different intervals along two years. The samples of serum were submitted to the microneutralization and hemaggIutination-inibition tests. Out of the 47 maned wolfs vaccinated during the experiment, none presented any type of undesirable reaction after the vaccination. The results about serologicalsurvey showed that: a) 68% of the maned wolves had neutralizing_ antibodis (NA) against CDV higher than 30 prior to vaccination; b) 80% of the specimens had antibodies measurable titers against CPV equal or higher · than B0. Post-vaccinal raponse demonstrated that the maned wolves are Y capable to develop antibodies against CDV and CPV after the vaccination. The modihedlive vaccine used in this experiment proved to be safe and immunogenic to the maned wolves.