Efeito da administração de deslorelina na indução de estro em cadelas no anestro
| Ano de defesa: | 2008 |
|---|---|
| Autor(a) principal: | |
| Orientador(a): | |
| Banca de defesa: | |
| Tipo de documento: | Dissertação |
| Tipo de acesso: | Acesso aberto |
| Idioma: | por |
| Instituição de defesa: |
Universidade Federal de Minas Gerais
|
| Programa de Pós-Graduação: |
Não Informado pela instituição
|
| Departamento: |
Não Informado pela instituição
|
| País: |
Não Informado pela instituição
|
| Palavras-chave em Português: | |
| Link de acesso: | https://hdl.handle.net/1843/LGPD-7Q2MRC |
Resumo: | The efficacy of an injectable formulation of deslorelin (a GnRH agonist) was evaluated to induce estrus in anestrous bitches, with one or multiple deslorelin doses. Thirteen animals composed three groups: Group 1 (n=5, single IM injection of 2,0mg of deslorelin), Group 2 (n=5, four IM injections of 2,0mg of deslorelin in alternate days) and Control Group (n=3, four IM saline injections in alternate days). Daily clinical evaluations, sexual behavior, vaginal cytology, plasma progesterone concentration, ovaryhysterectomy and macroscopic evaluation of the uterus and ovaries were done. In Group 1 none of the bitches showed signs of estrus, while two developed clinical signs and vaginal cytology of proestrus. In Group 2 all animals presented proestrus, four presented estrus and three ovulated, resulting in a functional corpus luteum, and high progesterone concentration until day 25 of diestrus, when ovaryhysterectomy was performed. The duration of the stages of deslorelin induced cycles and the progesterone profile were similar to those described in the literature, and no side effects were observed. In conclusion, deslorelin injectable formulation in multiple injections was effective to induce fertile estrus in anestrous bitches |
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Efeito da administração de deslorelina na indução de estro em cadelas no anestroVeterináriaReprodução animalEstroCadela ReproduçãoCiclo estralcadelasdeslorelinaindução de estroThe efficacy of an injectable formulation of deslorelin (a GnRH agonist) was evaluated to induce estrus in anestrous bitches, with one or multiple deslorelin doses. Thirteen animals composed three groups: Group 1 (n=5, single IM injection of 2,0mg of deslorelin), Group 2 (n=5, four IM injections of 2,0mg of deslorelin in alternate days) and Control Group (n=3, four IM saline injections in alternate days). Daily clinical evaluations, sexual behavior, vaginal cytology, plasma progesterone concentration, ovaryhysterectomy and macroscopic evaluation of the uterus and ovaries were done. In Group 1 none of the bitches showed signs of estrus, while two developed clinical signs and vaginal cytology of proestrus. In Group 2 all animals presented proestrus, four presented estrus and three ovulated, resulting in a functional corpus luteum, and high progesterone concentration until day 25 of diestrus, when ovaryhysterectomy was performed. The duration of the stages of deslorelin induced cycles and the progesterone profile were similar to those described in the literature, and no side effects were observed. In conclusion, deslorelin injectable formulation in multiple injections was effective to induce fertile estrus in anestrous bitchesUniversidade Federal de Minas Gerais2019-08-12T12:50:59Z2025-09-08T22:52:32Z2019-08-12T12:50:59Z2008-01-30info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisapplication/pdfhttps://hdl.handle.net/1843/LGPD-7Q2MRCLeonardo Lara e Lannainfo:eu-repo/semantics/openAccessporreponame:Repositório Institucional da UFMGinstname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMG2025-09-08T22:52:32Zoai:repositorio.ufmg.br:1843/LGPD-7Q2MRCRepositório InstitucionalPUBhttps://repositorio.ufmg.br/oairepositorio@ufmg.bropendoar:2025-09-08T22:52:32Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)false |
| dc.title.none.fl_str_mv |
Efeito da administração de deslorelina na indução de estro em cadelas no anestro |
| title |
Efeito da administração de deslorelina na indução de estro em cadelas no anestro |
| spellingShingle |
Efeito da administração de deslorelina na indução de estro em cadelas no anestro Leonardo Lara e Lanna Veterinária Reprodução animal Estro Cadela Reprodução Ciclo estral cadelas deslorelina indução de estro |
| title_short |
Efeito da administração de deslorelina na indução de estro em cadelas no anestro |
| title_full |
Efeito da administração de deslorelina na indução de estro em cadelas no anestro |
| title_fullStr |
Efeito da administração de deslorelina na indução de estro em cadelas no anestro |
| title_full_unstemmed |
Efeito da administração de deslorelina na indução de estro em cadelas no anestro |
| title_sort |
Efeito da administração de deslorelina na indução de estro em cadelas no anestro |
| author |
Leonardo Lara e Lanna |
| author_facet |
Leonardo Lara e Lanna |
| author_role |
author |
| dc.contributor.author.fl_str_mv |
Leonardo Lara e Lanna |
| dc.subject.por.fl_str_mv |
Veterinária Reprodução animal Estro Cadela Reprodução Ciclo estral cadelas deslorelina indução de estro |
| topic |
Veterinária Reprodução animal Estro Cadela Reprodução Ciclo estral cadelas deslorelina indução de estro |
| description |
The efficacy of an injectable formulation of deslorelin (a GnRH agonist) was evaluated to induce estrus in anestrous bitches, with one or multiple deslorelin doses. Thirteen animals composed three groups: Group 1 (n=5, single IM injection of 2,0mg of deslorelin), Group 2 (n=5, four IM injections of 2,0mg of deslorelin in alternate days) and Control Group (n=3, four IM saline injections in alternate days). Daily clinical evaluations, sexual behavior, vaginal cytology, plasma progesterone concentration, ovaryhysterectomy and macroscopic evaluation of the uterus and ovaries were done. In Group 1 none of the bitches showed signs of estrus, while two developed clinical signs and vaginal cytology of proestrus. In Group 2 all animals presented proestrus, four presented estrus and three ovulated, resulting in a functional corpus luteum, and high progesterone concentration until day 25 of diestrus, when ovaryhysterectomy was performed. The duration of the stages of deslorelin induced cycles and the progesterone profile were similar to those described in the literature, and no side effects were observed. In conclusion, deslorelin injectable formulation in multiple injections was effective to induce fertile estrus in anestrous bitches |
| publishDate |
2008 |
| dc.date.none.fl_str_mv |
2008-01-30 2019-08-12T12:50:59Z 2019-08-12T12:50:59Z 2025-09-08T22:52:32Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
| format |
masterThesis |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
https://hdl.handle.net/1843/LGPD-7Q2MRC |
| url |
https://hdl.handle.net/1843/LGPD-7Q2MRC |
| dc.language.iso.fl_str_mv |
por |
| language |
por |
| dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.format.none.fl_str_mv |
application/pdf |
| dc.publisher.none.fl_str_mv |
Universidade Federal de Minas Gerais |
| publisher.none.fl_str_mv |
Universidade Federal de Minas Gerais |
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reponame:Repositório Institucional da UFMG instname:Universidade Federal de Minas Gerais (UFMG) instacron:UFMG |
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Universidade Federal de Minas Gerais (UFMG) |
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UFMG |
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UFMG |
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Repositório Institucional da UFMG |
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Repositório Institucional da UFMG |
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Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG) |
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repositorio@ufmg.br |
| _version_ |
1879513127968571392 |