Dinâmica de expressão de interleucinas no intestino de pintainhos de diferentes linhagens desafiados com salmonella enteritidis

• Ano de defesa: 2018
• Autor(a) principal: Santos, Maylane Rayane Brito dos
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal da Paraíba; Brasil; Zootecnia; Programa de Pós-Graduação em Zootecnia; UFPB
• Palavras-chave em Português: ceco; genótipos; inoculação; linhagens; pro-inflamatórias; tolerância; CNPQ::CIENCIAS AGRARIAS
• Link de acesso: https://repositorio.ufpb.br/jspui/handle/123456789/30645

The objective of this study was to evaluate the behavior of interleukins in poultry commercial and neck naked challenged Salmonella Enteritidis challenged. A total of 200 eggs from the Cobb500® and Label Rouge® lines were used in the incubation, of these 100 chickens were used in the experiment. The evaluations were performed in the pre-initial phase (1-9 days). The parameters analyzed were bacterial count (CFU / mL) and relative expression of interleukins (IL-1, IL-8, IL-17 and IL-22). The animals were arranged in a completely randomized design (CRD) with 25 replicates, forming 4 treatments: Cobb500® line without challenge of Salmonella after hatching (Cobb-SS); Cobb500® line and challenge with post-hatching Salmonella (Cobb-CS); Label Rouge® line without challenge of Salmonella after hatching (LR-SS); Label Rouge® line and post-hatch Salmonella challenge (LR-CS). The Cobb500® line presented higher cecal bacterial counts in the period of 168 hpi. The different genotypes use differentiated routes in the two challenge situations, Label Rouge® is linked to the cytokines that are expressed by heterophiles. The relative expression of interleukins showed that there is a different dynamics between the lines. The Label Rouge® line shows earlier development of tolerance to S. Enteritidis than the Cobb500® lineage.