State dependent complexity of local field potentials in the primary visual cortex
| Ano de defesa: | 2024 |
|---|---|
| Autor(a) principal: | |
| Orientador(a): | |
| Banca de defesa: | |
| Tipo de documento: | Tese |
| Tipo de acesso: | Acesso aberto |
| Idioma: | eng |
| Instituição de defesa: |
Universidade Federal de Pernambuco
UFPE Brasil Programa de Pos Graduacao em Fisica |
| Programa de Pós-Graduação: |
Não Informado pela instituição
|
| Departamento: |
Não Informado pela instituição
|
| País: |
Não Informado pela instituição
|
| Palavras-chave em Português: | |
| Link de acesso: | https://repositorio.ufpe.br/handle/123456789/59229 |
Resumo: | The Local field potential (LFP) captures the combined electric activity of neurons in a region of brain tissue. Although widely used to study brain rhythms and neural circuits, the precise relationship between LFPs and spiking activity remains poorly understood, in particular, regarding cortical state. Using a symbolic representation based on Bandt-Pompe technique, this work bridges that gap by finding consistent relations between cortical state, as proxied by the coefficient of variation (CV) of spiking activity and information-theory quantifiers-Shannon entropy and statistical complexity—of LFP data from urethane-anesthetized rats and freely moving mice. Our findings demonstrate that LFP’s statistical complexity and Shannon entropy in the deep layers of the primary visual cortex (V1) vary consistently with spiking variability. We further explored these quantifiers across cortical layers in V1, showing that statistical complexity is sensitive to depth, peaking in mid-layer 5 as CV increases. Additionally, we show LFP’s statistical complexity varies across behavioral states of freely moving mice. |
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State dependent complexity of local field potentials in the primary visual cortexLFPEstado corticalComplexidade estatísticaVariabilidade de disparoThe Local field potential (LFP) captures the combined electric activity of neurons in a region of brain tissue. Although widely used to study brain rhythms and neural circuits, the precise relationship between LFPs and spiking activity remains poorly understood, in particular, regarding cortical state. Using a symbolic representation based on Bandt-Pompe technique, this work bridges that gap by finding consistent relations between cortical state, as proxied by the coefficient of variation (CV) of spiking activity and information-theory quantifiers-Shannon entropy and statistical complexity—of LFP data from urethane-anesthetized rats and freely moving mice. Our findings demonstrate that LFP’s statistical complexity and Shannon entropy in the deep layers of the primary visual cortex (V1) vary consistently with spiking variability. We further explored these quantifiers across cortical layers in V1, showing that statistical complexity is sensitive to depth, peaking in mid-layer 5 as CV increases. Additionally, we show LFP’s statistical complexity varies across behavioral states of freely moving mice.O potencial de campo local (LFP) captura a atividade elétrica combinada dos neurônios em uma região do tecido cerebral. Embora amplamente utilizado para estudar ritmos cerebrais e circuitos neurais, a relação precisa entre os LFPs e a atividade de disparo de neurônios ainda é pouco compreendida, especialmente no que diz respeito ao estado cortical. Utilizando uma rep- resentação simbólica baseada na técnica de Bandt-Pompe, este trabalho preenche essa lacuna ao encontrar relações consistentes entre o estado cortical, representado pelo coeficiente de variação (CV) da atividade de disparo, e os quantificadores de teoria da informação—entropia de Shannon e complexidade estatística—de dados de LFP obtidos de ratos anestesiados com uretana e camundongos em movimento livre. Nossos resultados demonstram que a complex- idade estatística e a entropia de Shannon dos LFPs nas camadas profundas do córtex visual primário (V1) variam consistentemente com a variabilidade de disparo dos neurônios. Explo- ramos ainda esses quantificadores ao longo das camadas corticais no V1, mostrando que a complexidade estatística é sensível à profundidade, atingindo seu pico na metade da camada 5 à medida que o CV aumenta. Além disso, mostramos que a complexidade estatística dos LFPs varia entre diferentes estados comportamentais dos camundongos em movimento livre.Universidade Federal de PernambucoUFPEBrasilPrograma de Pos Graduacao em FisicaCARELLI, Pedro ValadãoVASCONCELOS, Nivaldo Antônio Portela dehttp://lattes.cnpq.br/3576318910439025http://lattes.cnpq.br/0869469262114149http://lattes.cnpq.br/4110109220389767JUNGMANN, Rafael Magalhães2024-12-17T15:35:15Z2024-12-17T15:35:15Z2024-12-02info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/doctoralThesisapplication/pdfJUNGMANN, Rafael Magalhães. State dependent complexity of local field potentials in the primary visual cortex. 2024. Tese (Doutorado em Física) – Universidade Federal de Pernambuco, Recife, 2024.https://repositorio.ufpe.br/handle/123456789/59229enghttp://creativecommons.org/licenses/by-nc-nd/3.0/br/info:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFPEinstname:Universidade Federal de Pernambuco (UFPE)instacron:UFPE2025-01-23T05:36:57Zoai:repositorio.ufpe.br:123456789/59229Repositório InstitucionalPUBhttps://repositorio.ufpe.br/oai/requestattena@ufpe.bropendoar:22212025-01-23T05:36:57Repositório Institucional da UFPE - Universidade Federal de Pernambuco (UFPE)false |
| dc.title.none.fl_str_mv |
State dependent complexity of local field potentials in the primary visual cortex |
| title |
State dependent complexity of local field potentials in the primary visual cortex |
| spellingShingle |
State dependent complexity of local field potentials in the primary visual cortex JUNGMANN, Rafael Magalhães LFP Estado cortical Complexidade estatística Variabilidade de disparo |
| title_short |
State dependent complexity of local field potentials in the primary visual cortex |
| title_full |
State dependent complexity of local field potentials in the primary visual cortex |
| title_fullStr |
State dependent complexity of local field potentials in the primary visual cortex |
| title_full_unstemmed |
State dependent complexity of local field potentials in the primary visual cortex |
| title_sort |
State dependent complexity of local field potentials in the primary visual cortex |
| author |
JUNGMANN, Rafael Magalhães |
| author_facet |
JUNGMANN, Rafael Magalhães |
| author_role |
author |
| dc.contributor.none.fl_str_mv |
CARELLI, Pedro Valadão VASCONCELOS, Nivaldo Antônio Portela de http://lattes.cnpq.br/3576318910439025 http://lattes.cnpq.br/0869469262114149 http://lattes.cnpq.br/4110109220389767 |
| dc.contributor.author.fl_str_mv |
JUNGMANN, Rafael Magalhães |
| dc.subject.por.fl_str_mv |
LFP Estado cortical Complexidade estatística Variabilidade de disparo |
| topic |
LFP Estado cortical Complexidade estatística Variabilidade de disparo |
| description |
The Local field potential (LFP) captures the combined electric activity of neurons in a region of brain tissue. Although widely used to study brain rhythms and neural circuits, the precise relationship between LFPs and spiking activity remains poorly understood, in particular, regarding cortical state. Using a symbolic representation based on Bandt-Pompe technique, this work bridges that gap by finding consistent relations between cortical state, as proxied by the coefficient of variation (CV) of spiking activity and information-theory quantifiers-Shannon entropy and statistical complexity—of LFP data from urethane-anesthetized rats and freely moving mice. Our findings demonstrate that LFP’s statistical complexity and Shannon entropy in the deep layers of the primary visual cortex (V1) vary consistently with spiking variability. We further explored these quantifiers across cortical layers in V1, showing that statistical complexity is sensitive to depth, peaking in mid-layer 5 as CV increases. Additionally, we show LFP’s statistical complexity varies across behavioral states of freely moving mice. |
| publishDate |
2024 |
| dc.date.none.fl_str_mv |
2024-12-17T15:35:15Z 2024-12-17T15:35:15Z 2024-12-02 |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/doctoralThesis |
| format |
doctoralThesis |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
JUNGMANN, Rafael Magalhães. State dependent complexity of local field potentials in the primary visual cortex. 2024. Tese (Doutorado em Física) – Universidade Federal de Pernambuco, Recife, 2024. https://repositorio.ufpe.br/handle/123456789/59229 |
| identifier_str_mv |
JUNGMANN, Rafael Magalhães. State dependent complexity of local field potentials in the primary visual cortex. 2024. Tese (Doutorado em Física) – Universidade Federal de Pernambuco, Recife, 2024. |
| url |
https://repositorio.ufpe.br/handle/123456789/59229 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
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http://creativecommons.org/licenses/by-nc-nd/3.0/br/ info:eu-repo/semantics/openAccess |
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http://creativecommons.org/licenses/by-nc-nd/3.0/br/ |
| eu_rights_str_mv |
openAccess |
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application/pdf |
| dc.publisher.none.fl_str_mv |
Universidade Federal de Pernambuco UFPE Brasil Programa de Pos Graduacao em Fisica |
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Universidade Federal de Pernambuco UFPE Brasil Programa de Pos Graduacao em Fisica |
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reponame:Repositório Institucional da UFPE instname:Universidade Federal de Pernambuco (UFPE) instacron:UFPE |
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Universidade Federal de Pernambuco (UFPE) |
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UFPE |
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Repositório Institucional da UFPE - Universidade Federal de Pernambuco (UFPE) |
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attena@ufpe.br |
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