Avaliação histológica da polpa dental de suínos após capeamento com Agregado Trióxido Mineral ou Hidróxido de Cálcio

Detalhes bibliográficos
Ano de defesa: 2006
Autor(a) principal: Leites, Antonio Cesar Bortowiski Rosa
Orientador(a): Piva, Evandro
Banca de defesa: Não Informado pela instituição
Tipo de documento: Tese
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Federal de Pelotas
Programa de Pós-Graduação: Programa de Pós-Graduação em Odontologia
Departamento: Odontologia
País: BR
Palavras-chave em Português:
Palavras-chave em Inglês:
Área do conhecimento CNPq:
Link de acesso: http://guaiaca.ufpel.edu.br/handle/123456789/2299
Resumo: The main objectives of this study were to evaluate the use of the Sus scrofa domesticus swine in dental pulp experiments and analyze the histological pulp reaction to the direct application of mineral trioxide aggregate (MTA Angelus) and cement containing calcium hydroxide (Dycal). Class V cavities were prepared on incisors and pre-molar deciduous teeth of swine originated from crossbreed between Landrace and Large White of about 105 (±10 days) days old. Pulp exposures were obtained and after their homeostasis with saline, pulp capping was done with direct application of either MTA or Dycal. The animals were slaughtered after a period ranging within 7 and 70 days according to ISO 7405:1997. Four groups were created combining times and materials (HC_7d, HC_70d, MTA_7d and MTA_70d). The teeth were extracted and processed by HE histological technique; randomized cuts were examined under optical microscope with 100X enlargement by two different examiners. The criteria evaluated were: inflammatory response, tissue organization, reactive and reparative dentin being them all classified according to ISO 7405:1997 criteria. The Mann-Whitney Statistical test was used to compare both groups (α=5%). The MTA showed a tendency to accelerate the pulp healing process, being reparative dentin apposition initiated in the early stages of the healing process. Both materials showed similar pulp healing characteristics after 70 days. Despite higher levels of initial inflammation, specially related to Calcium Hydroxide (p<0.05), there was a remarkable formation of tertiary dentin after the period of 70 days, which shows the ability of swine dental pulp to respond to stimuli provoked by the materials used. The kind of animal used may give us an economically feasible model for further pulp response studies.
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spelling Antonio Cesar Bortowiski Rosa Leiteshttp://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4701753T0Piva, EvandroLeites, Antonio Cesar Bortowiski Rosa2014-08-20T14:30:18Z2013-12-132014-08-20T14:30:18Z2006-07-05LEITES, Antonio Cesar Bortowiski Rosa. Histological evaluation of swine dental pulp after their capping either with mineral trioxide aggregate or calcium hydroxide. 2006. 112 f. Tese (Doutorado em Odontologia) - Universidade Federal de Pelotas, Pelotas, 2006.http://guaiaca.ufpel.edu.br/handle/123456789/2299The main objectives of this study were to evaluate the use of the Sus scrofa domesticus swine in dental pulp experiments and analyze the histological pulp reaction to the direct application of mineral trioxide aggregate (MTA Angelus) and cement containing calcium hydroxide (Dycal). Class V cavities were prepared on incisors and pre-molar deciduous teeth of swine originated from crossbreed between Landrace and Large White of about 105 (±10 days) days old. Pulp exposures were obtained and after their homeostasis with saline, pulp capping was done with direct application of either MTA or Dycal. The animals were slaughtered after a period ranging within 7 and 70 days according to ISO 7405:1997. Four groups were created combining times and materials (HC_7d, HC_70d, MTA_7d and MTA_70d). The teeth were extracted and processed by HE histological technique; randomized cuts were examined under optical microscope with 100X enlargement by two different examiners. The criteria evaluated were: inflammatory response, tissue organization, reactive and reparative dentin being them all classified according to ISO 7405:1997 criteria. The Mann-Whitney Statistical test was used to compare both groups (α=5%). The MTA showed a tendency to accelerate the pulp healing process, being reparative dentin apposition initiated in the early stages of the healing process. Both materials showed similar pulp healing characteristics after 70 days. Despite higher levels of initial inflammation, specially related to Calcium Hydroxide (p<0.05), there was a remarkable formation of tertiary dentin after the period of 70 days, which shows the ability of swine dental pulp to respond to stimuli provoked by the materials used. The kind of animal used may give us an economically feasible model for further pulp response studies.O presente trabalho teve como objetivos avaliar o uso de suínos da espécie Sus scrofa domesticus para experimentos em polpa dental e analisar a resposta histológica pulpar mediante a aplicação direta de agregado trióxido mineral (MTA Angelus®) e cimento contendo Hidróxido de Cálcio (Dycal®). Cavidades classes V foram preparadas em dentes incisivos e pré-molares decíduos inferiores de suínos oriundos do cruzamento de raças Landrace e Large White com idade aproximada de 105 dias (±10 dias). Exposições pulpares foram obtidas e após hemostasia com soro fisiológico, foi realizado capeamento pulpar com a aplicação direta de MTA ou Dycal. Os animais foram abatidos após o período de 7 ou 70 dias de acordo com a ISO 7405:1997. Quatro grupos foram criados a partir da combinação de tempos e materiais (HC_7d, HC_70d, MTA_7d e MTA_70d). Os dentes foram extraídos e processados pela técnica histológica de HE, com cortes aleatorizados sendo examinados ao microscópio óptico em 100x de aumento por dois examinadores. Os critérios avaliados foram: resposta inflamatória, organização tecidual, dentina reacional e reparativa, classificados de acordo com os critérios da ISO 7405:1997. Foi utilizado o teste estatístico de Mann-Whitney para realizar as comparações entre dois grupos (?=5%). O MTA demonstrou uma tendência em acelerar o processo de regeneração pulpar, iniciando a deposição de dentina reparativa ainda nas primeiras fases do reparo. Ambos materiais apresentaram características de reparo pulpar similar após 70 dias. Apesar de maiores níveis significantes deinflamação inicial, especialmente associado ao Hidróxido de Cálcio (p< 0,05), houve uma marcante formação de dentina terciária ao final de 70 dias, demonstrando a capacidade da polpa dental de suínos em responder aos estímulos provocados pelos materiais utilizados. O tipo de animal empregado parece fornecer um modelo economicamente viável para estudos de resposta pulpar.application/pdfporUniversidade Federal de PelotasPrograma de Pós-Graduação em OdontologiaUFPelBROdontologiaAgregado trióxido mineralCapeamento pulpar diretoCimentos dentáriosDentição decícuaHidróxido de cálciosuínoDentísticaMineral trioxide aggregateDirect pulp cappingDental cementDeciduous teethingCalcium hydroxideSwineCNPQ::CIENCIAS DA SAUDE::ODONTOLOGIAAvaliação histológica da polpa dental de suínos após capeamento com Agregado Trióxido Mineral ou Hidróxido de CálcioHistological evaluation of swine dental pulp after their capping either with mineral trioxide aggregate or calcium hydroxideinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/doctoralThesisinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFPel - Guaiacainstname:Universidade Federal de Pelotas (UFPEL)instacron:UFPELTEXTAntonio Cesar Bortowiski Rosa Leites.pdf.txtAntonio Cesar Bortowiski Rosa Leites.pdf.txtExtracted texttext/plain178404http://guaiaca.ufpel.edu.br/xmlui/bitstream/123456789/2299/3/Antonio%20Cesar%20Bortowiski%20Rosa%20Leites.pdf.txte70cfef65a286321e0afdb2f9c12a6caMD53open accessORIGINALAntonio Cesar Bortowiski Rosa Leites.pdfapplication/pdf1822145http://guaiaca.ufpel.edu.br/xmlui/bitstream/123456789/2299/1/Antonio%20Cesar%20Bortowiski%20Rosa%20Leites.pdf915d378526f9e0881629bd5697d4d9e1MD51open accessTHUMBNAILAntonio Cesar Bortowiski Rosa Leites.pdf.jpgAntonio Cesar Bortowiski Rosa Leites.pdf.jpgGenerated Thumbnailimage/jpeg2034http://guaiaca.ufpel.edu.br/xmlui/bitstream/123456789/2299/2/Antonio%20Cesar%20Bortowiski%20Rosa%20Leites.pdf.jpgdcbb687d19643dae871036493a44858fMD52open access123456789/22992023-07-13 05:19:58.831open accessoai:guaiaca.ufpel.edu.br:123456789/2299Repositório InstitucionalPUBhttp://repositorio.ufpel.edu.br/oai/requestrippel@ufpel.edu.br || repositorio@ufpel.edu.br || aline.batista@ufpel.edu.bropendoar:2023-07-13T08:19:58Repositório Institucional da UFPel - Guaiaca - Universidade Federal de Pelotas (UFPEL)false
dc.title.por.fl_str_mv Avaliação histológica da polpa dental de suínos após capeamento com Agregado Trióxido Mineral ou Hidróxido de Cálcio
dc.title.alternative.eng.fl_str_mv Histological evaluation of swine dental pulp after their capping either with mineral trioxide aggregate or calcium hydroxide
title Avaliação histológica da polpa dental de suínos após capeamento com Agregado Trióxido Mineral ou Hidróxido de Cálcio
spellingShingle Avaliação histológica da polpa dental de suínos após capeamento com Agregado Trióxido Mineral ou Hidróxido de Cálcio
Leites, Antonio Cesar Bortowiski Rosa
Agregado trióxido mineral
Capeamento pulpar direto
Cimentos dentários
Dentição decícua
Hidróxido de cálcio
suíno
Dentística
Mineral trioxide aggregate
Direct pulp capping
Dental cement
Deciduous teething
Calcium hydroxide
Swine
CNPQ::CIENCIAS DA SAUDE::ODONTOLOGIA
title_short Avaliação histológica da polpa dental de suínos após capeamento com Agregado Trióxido Mineral ou Hidróxido de Cálcio
title_full Avaliação histológica da polpa dental de suínos após capeamento com Agregado Trióxido Mineral ou Hidróxido de Cálcio
title_fullStr Avaliação histológica da polpa dental de suínos após capeamento com Agregado Trióxido Mineral ou Hidróxido de Cálcio
title_full_unstemmed Avaliação histológica da polpa dental de suínos após capeamento com Agregado Trióxido Mineral ou Hidróxido de Cálcio
title_sort Avaliação histológica da polpa dental de suínos após capeamento com Agregado Trióxido Mineral ou Hidróxido de Cálcio
author Leites, Antonio Cesar Bortowiski Rosa
author_facet Leites, Antonio Cesar Bortowiski Rosa
author_role author
dc.contributor.authorLattes.por.fl_str_mv Antonio Cesar Bortowiski Rosa Leites
dc.contributor.advisorLattes.por.fl_str_mv http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4701753T0
dc.contributor.advisor1.fl_str_mv Piva, Evandro
dc.contributor.author.fl_str_mv Leites, Antonio Cesar Bortowiski Rosa
contributor_str_mv Piva, Evandro
dc.subject.por.fl_str_mv Agregado trióxido mineral
Capeamento pulpar direto
Cimentos dentários
Dentição decícua
Hidróxido de cálcio
suíno
Dentística
topic Agregado trióxido mineral
Capeamento pulpar direto
Cimentos dentários
Dentição decícua
Hidróxido de cálcio
suíno
Dentística
Mineral trioxide aggregate
Direct pulp capping
Dental cement
Deciduous teething
Calcium hydroxide
Swine
CNPQ::CIENCIAS DA SAUDE::ODONTOLOGIA
dc.subject.eng.fl_str_mv Mineral trioxide aggregate
Direct pulp capping
Dental cement
Deciduous teething
Calcium hydroxide
Swine
dc.subject.cnpq.fl_str_mv CNPQ::CIENCIAS DA SAUDE::ODONTOLOGIA
description The main objectives of this study were to evaluate the use of the Sus scrofa domesticus swine in dental pulp experiments and analyze the histological pulp reaction to the direct application of mineral trioxide aggregate (MTA Angelus) and cement containing calcium hydroxide (Dycal). Class V cavities were prepared on incisors and pre-molar deciduous teeth of swine originated from crossbreed between Landrace and Large White of about 105 (±10 days) days old. Pulp exposures were obtained and after their homeostasis with saline, pulp capping was done with direct application of either MTA or Dycal. The animals were slaughtered after a period ranging within 7 and 70 days according to ISO 7405:1997. Four groups were created combining times and materials (HC_7d, HC_70d, MTA_7d and MTA_70d). The teeth were extracted and processed by HE histological technique; randomized cuts were examined under optical microscope with 100X enlargement by two different examiners. The criteria evaluated were: inflammatory response, tissue organization, reactive and reparative dentin being them all classified according to ISO 7405:1997 criteria. The Mann-Whitney Statistical test was used to compare both groups (α=5%). The MTA showed a tendency to accelerate the pulp healing process, being reparative dentin apposition initiated in the early stages of the healing process. Both materials showed similar pulp healing characteristics after 70 days. Despite higher levels of initial inflammation, specially related to Calcium Hydroxide (p<0.05), there was a remarkable formation of tertiary dentin after the period of 70 days, which shows the ability of swine dental pulp to respond to stimuli provoked by the materials used. The kind of animal used may give us an economically feasible model for further pulp response studies.
publishDate 2006
dc.date.issued.fl_str_mv 2006-07-05
dc.date.available.fl_str_mv 2013-12-13
2014-08-20T14:30:18Z
dc.date.accessioned.fl_str_mv 2014-08-20T14:30:18Z
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dc.type.driver.fl_str_mv info:eu-repo/semantics/doctoralThesis
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dc.identifier.citation.fl_str_mv LEITES, Antonio Cesar Bortowiski Rosa. Histological evaluation of swine dental pulp after their capping either with mineral trioxide aggregate or calcium hydroxide. 2006. 112 f. Tese (Doutorado em Odontologia) - Universidade Federal de Pelotas, Pelotas, 2006.
dc.identifier.uri.fl_str_mv http://guaiaca.ufpel.edu.br/handle/123456789/2299
identifier_str_mv LEITES, Antonio Cesar Bortowiski Rosa. Histological evaluation of swine dental pulp after their capping either with mineral trioxide aggregate or calcium hydroxide. 2006. 112 f. Tese (Doutorado em Odontologia) - Universidade Federal de Pelotas, Pelotas, 2006.
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